Prime MedicinePRME
13F holders, Q2 2026 (June 30)187holders −5
21new positions
23sold out
7famous investors
$3.69avg. 13F price*
At the end of Q2 2026, 187 institutions reported holding Prime Medicine Inc. (PRME) in their 13F filings, down 5 from Q1 2026. 21 opened new positions and 23 sold out. The largest holders were Alphabet Inc. ($61.1M), BlackRock, Inc. ($35.4M) and ARK Investment Management ($30.8M). 7 famous investors held it, including Cathie Wood (0.2% of ARK Investment Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Prime Medicine Inc.
- CUSIP
- 74168J101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $11.8M |
| Exits | 23 | $1.8M |
All 13F filers, Q1 2026 → Q2 2026: 13,721,636 shares bought and 5,606,744 shares sold, net +8,114,892 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 187 holders
| Alphabet Inc. | 0.06% | No change | 16,562,498 | $61.1M |
| BlackRock, Inc. | 0.00% | Add +12.9% | 9,602,041 | $35.4M |
| ARK Investment Management | 0.20% | Add +33.6% | 8,348,746 | $30.8M |
| State Street Corp. | 0.00% | Add +19.4% | 7,576,460 | $28.0M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Reduce -4.5% | 5,237,332 | $19.3M |
| Vanguard Capital Management LLC | 0.00% | Add +1.1% | 4,522,640 | $16.7M |
| Balyasny Asset Management L.P. | 0.03% | Reduce -3.7% | 3,969,082 | $14.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +253.5% | 3,430,518 | $12.7M |
| Casdin Capital, LLC | 0.58% | No change | 3,167,175 | $11.7M |
| Woodline Partners LP | 0.03% | Add +0.0% | 3,003,904 | $11.1M |
| UBS Group AG | 0.00% | Reduce -3.2% | 2,794,689 | $10.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -1.1% | 2,712,446 | $10.0M |
| Sumitomo Mitsui Trust Group, Inc. | 0.01% | Reduce -17.9% | 2,412,984 | $8.9M |
| Amova Asset Management Americas, Inc. | 0.11% | Reduce -18.1% | 2,407,018 | $8.9M |
| Citadel Advisors | 0.00% | Add +510.8% | 2,054,543 | $7.6M |
| ADAR1 Capital Management, LLC | 0.35% | Add +1.2% | 1,997,552 | $7.4M |
| FMR LLC | 0.00% | Reduce -0.4% | 1,761,884 | $6.5M |
| Two Sigma Investments, LP | 0.00% | Reduce -3.1% | 1,524,511 | $5.6M |
| Redmile Group, LLC | 0.34% | Reduce -12.7% | 1,389,632 | $5.1M |
| Farallon Capital Management, L.L.C. | 0.03% | No change | 1,240,843 | $4.6M |
| Jump Financial, LLC | 0.04% | New | 1,240,429 | $4.6M |
| Bank of America Corp. | 0.00% | Add +70.1% | 981,335 | $3.6M |
| Vanguard Portfolio Management LLC | 0.00% | Add +11.6% | 961,826 | $3.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.1% | 927,538 | $3.4M |
| Northern Trust Corp. | 0.00% | Add +2.9% | 912,597 | $3.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -4.0% | 810,095 | $3.0M |
| Greenwich Wealth Management LLC | 0.10% | Add +2.4% | 768,001 | $2.8M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +6.6% | 764,633 | $2.8M |
| Morgan Stanley | 0.00% | Add +10.9% | 708,963 | $2.6M |
| Alessandra Capital Management, LLC | 1.74% | Add +56.7% | 666,603 | $2.5M |
| D. E. Shaw & Co. | 0.00% | Reduce -53.4% | 648,940 | $2.4M |
| Susquehanna International Group, LLP | 0.00% | Reduce -9.4% | 648,479 | $2.4M |
| Point72 Asset Management | 0.00% | New | 533,553 | $2.0M |
| Moore Capital Management, LP | 0.04% | No change | 500,000 | $1.8M |
| Chelsea Counsel Co. | 0.70% | Reduce -2.9% | 449,060 | $1.7M |
| Millennium Management | 0.00% | New | 427,097 | $1.6M |
| HighTower Advisors, LLC | 0.00% | Add +0.0% | 340,365 | $1.3M |
| Dimensional Fund Advisors LP | 0.00% | Add +0.1% | 304,678 | $1.1M |
| Wellington Management Group LLP | 0.00% | Add +9.5% | 304,444 | $1.1M |
| Nuveen, LLC | 0.00% | No change | 275,931 | $1.0M |
| Wells Fargo & Company | 0.00% | Reduce -21.2% | 251,747 | $929K |
| Bank of New York Mellon Corp | 0.00% | Reduce -7.8% | 246,344 | $909K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.05% | Add +9.9% | 225,799 | $833K |
| Marshall Wace, LLP | 0.00% | Add +52.8% | 216,841 | $800K |
| XTX Topco Ltd | 0.01% | Add +37.1% | 215,708 | $796K |
| Jain Global LLC | 0.01% | New | 215,218 | $794K |
| Jupiter Asset Management Ltd. | 0.00% | New | 209,490 | $773K |
| Swiss National Bank | 0.00% | Add +16.6% | 208,300 | $769K |
| PEAK6 LLC | 0.02% | New | 208,057 | $768K |
| Citigroup Inc. | 0.00% | Add +314.3% | 195,664 | $722K |
| Green Alpha Advisors, LLC | 0.46% | Reduce -3.2% | 185,023 | $683K |
| Keystone Financial Group | 0.04% | Add +0.3% | 166,510 | $614K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +32.6% | 162,338 | $600K |
| T. Rowe Price Associates Inc. | 0.00% | Add +21.4% | 162,325 | $599K |
| HRT Financial LP | 0.00% | Reduce -73.6% | 161,510 | $595K |
| California State Teachers Retirement System | 0.00% | Add +81.6% | 157,049 | $580K |
| Bollard Group LLC | 0.02% | Reduce -58.1% | 151,136 | $558K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -32.6% | 145,275 | $536K |
| Alliancebernstein L.P. | 0.00% | Add +22.7% | 150,300 | $523K |
| Invesco Ltd. | 0.00% | Add +44.8% | 140,308 | $518K |
| Concurrent Investment Advisors, LLC | 0.00% | Add +77.6% | 131,722 | $486K |
| ExodusPoint Capital Management, LP | 0.00% | New | 118,464 | $437K |
| AQR Capital Management | 0.00% | Reduce -78.7% | 117,998 | $435K |
| Virtus Investment Advisers, LLC | 0.10% | Add +77.3% | 117,909 | $435K |
| Renaissance Technologies | 0.00% | Reduce -84.2% | 117,412 | $433K |
| Rhumbline Advisers | 0.00% | Add +2.2% | 116,754 | $431K |
| FIL Ltd | 0.00% | No change | 115,206 | $425K |
| Deutsche Bank AG | 0.00% | Reduce -27.3% | 114,472 | $422K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -7.8% | 108,290 | $400K |
| Palumbo Wealth Management LLC | 0.08% | Add +1.5% | 103,801 | $383K |
| Milestone Asset Management, LLC | 0.06% | New | 100,035 | $369K |
| TD Asset Management Inc | 0.00% | No change | 94,148 | $347K |
| LPL Financial LLC | 0.00% | Add +38.8% | 92,174 | $340K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -0.7% | 90,735 | $335K |
| Barclays PLC | 0.00% | Add +38.1% | 88,058 | $325K |
| Squarepoint Ops LLC | 0.00% | Reduce -6.4% | 88,029 | $325K |
| Commonwealth Equity Services, LLC | 0.00% | Add +431.2% | 87,310 | $322K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | No change | 85,300 | $315K |
| Los Angeles Capital Management LLC | 0.00% | Add +56.4% | 82,305 | $304K |
| Profund Advisors LLC | 0.01% | Reduce -24.2% | 72,624 | $268K |
| Legal & General Group Plc | 0.00% | No change | 66,444 | $245K |
| BNP Paribas Financial Markets | 0.00% | Add +92.1% | 66,101 | $244K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -51.9% | 64,800 | $239K |
| Jupiter Topco LLC | 0.00% | — | 60,900 | $224K |
| Engineers Gate Manager LP | 0.00% | Reduce -46.4% | 59,133 | $218K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | No change | 59,021 | $218K |
| SG Americas Securities, LLC | 0.00% | New | 58,922 | $217K |
| &partners | 0.00% | Reduce -3.4% | 57,460 | $211K |
| MetLife Investment Management, LLC | 0.00% | Add +27.1% | 56,192 | $207K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -20.7% | 50,994 | $188K |
| Ameriprise Financial Inc. | 0.00% | Add +0.7% | 49,941 | $184K |
| Mutual Advisors, LLC | 0.00% | Reduce -0.4% | 45,000 | $166K |
| Vanguard Global Advisers, LLC | 0.00% | No change | 44,269 | $163K |
| Quadrature Capital Ltd | 0.00% | Reduce -6.9% | 43,663 | $161K |
| IvyRock Asset Management (HK) Ltd | 0.09% | No change | 41,800 | $154K |
| Corient Private Wealth LP | 0.00% | Reduce -5.2% | 39,078 | $144K |
| Jones Financial Companies LLLP | 0.00% | Add +1.4% | 40,867 | $140K |
| State of New Jersey Common Pension Fund D | 0.00% | Add +8.8% | 33,569 | $124K |
| Crestwood Advisors Group, LLC | 0.00% | Reduce -1.0% | 32,041 | $118K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 30,751 | $113K |
| Oppenheimer & Co. Inc. | 0.00% | Reduce -11.9% | 29,650 | $109K |
| Raymond James Financial Inc. | 0.00% | Add +142.3% | 29,184 | $108K |
| Sei Investments Co. | 0.00% | No change | 29,183 | $108K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -10.3% | 28,745 | $106K |
| Arizona State Retirement System | 0.00% | Add +15.6% | 28,646 | $106K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -2.6% | 28,278 | $104K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -5.3% | 27,353 | $101K |
| Vanguard Investments Australia, Ltd. | 0.00% | No change | 26,124 | $96K |
| Blue Bell Private Wealth Management, LLC | 0.01% | Reduce -4.4% | 25,830 | $95K |
| Mariner, LLC | 0.00% | Reduce -67.6% | 25,389 | $94K |
| Abacus Planning Group, Inc. | 0.01% | No change | 25,188 | $93K |
| Intech Investment Management LLC | 0.00% | Reduce -20.2% | 24,363 | $90K |
| Creative Planning | 0.00% | Reduce -24.6% | 21,295 | $79K |
| Magnetar Financial LLC | 0.00% | Add +34.1% | 21,174 | $78K |
| E Fund Management Co., Ltd. | 0.00% | Reduce -24.4% | 20,484 | $76K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 20,189 | $74K |
| Voya Investment Management LLC | 0.00% | Add +16.1% | 20,138 | $74K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -8.5% | 20,083 | $74K |
| Shelton Wealth Management, LLC | 0.03% | Reduce -4.8% | 19,105 | $70K |
| Cibc World Market Inc. | 0.00% | New | 18,662 | $69K |
| Graham Capital Management, L.P. | 0.00% | Add +15.6% | 18,516 | $68K |
| KLP Kapitalforvaltning As | 0.00% | No change | 18,500 | $68K |
| ProShare Advisors LLC | 0.00% | Reduce -20.6% | 18,243 | $67K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 18,225 | $67K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +33.1% | 16,427 | $61K |
| Ieq Capital, LLC | 0.00% | Reduce -77.7% | 16,503 | $61K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -59.9% | 15,096 | $57K |
| Levin Capital Strategies, L.P. | 0.00% | No change | 15,000 | $55K |
| Prudential Financial Inc. | 0.00% | No change | 14,755 | $54K |
| Thompson Davis & Co., Inc. | 0.03% | Reduce -15.4% | 14,590 | $54K |
| Sanctuary Advisors, LLC | 0.00% | Reduce -3.6% | 13,400 | $49K |
| JTC Employer Solutions Trustee Ltd | 0.00% | No change | 13,249 | $49K |
| DRW Securities, LLC | 0.00% | Reduce -68.0% | 13,106 | $48K |
| Prime Capital Investment Advisors, LLC | 0.00% | No change | 12,945 | $48K |
| Brevan Howard Capital Management LP | 0.00% | New | 12,910 | $48K |
| State of Wisconsin Investment Board | 0.00% | New | 12,681 | $47K |
| Pictet Asset Management Holding SA | 0.00% | No change | 12,107 | $45K |
| Sequoia Financial Advisors, LLC | 0.00% | Add +0.1% | 11,686 | $43K |
| Teacher Retirement System of Texas | 0.00% | Add +3.5% | 11,440 | $42K |
| Wealthfront Advisers LLC | 0.00% | Add +8.9% | 11,301 | $42K |
| Syon Capital LLC | 0.00% | New | 11,077 | $41K |
| Victory Capital Management Inc. | 0.00% | Add +1.5% | 10,979 | $41K |
| Benjamin Edwards Inc. | 0.00% | Reduce -25.4% | 10,329 | $38K |
| Lanark Financial, Inc. | 0.00% | Add +100.0% | 10,000 | $37K |
| Forum Financial Management, LP | 0.00% | No change | 10,000 | $37K |
| Kingsview Wealth Management, LLC | 0.00% | Reduce -71.4% | 10,000 | $37K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 9,500 | $35K |
| Osaic Holdings, Inc. | 0.00% | Add +129.4% | 9,398 | $35K |
| New York State Common Retirement Fund | 0.00% | No change | 8,434 | $31K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 8,407 | $31K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -14.2% | 8,078 | $30K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -69.4% | 6,683 | $25K |
| Royal Bank of Canada | 0.00% | Reduce -36.8% | 5,853 | $22K |
| Glen Eagle Advisors, LLC | 0.00% | Reduce -50.0% | 5,000 | $18K |
| Signaturefd, LLC | 0.00% | No change | 5,000 | $18K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -51.4% | 4,544 | $17K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -5.3% | 3,822 | $14K |
| Owl Creek Wealth Partners LLC | 0.00% | No change | 2,615 | $10K |
| Pacer Advisors, Inc. | 0.00% | New | 2,426 | $9K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +329.2% | 1,644 | $6K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -31.2% | 1,376 | $5K |
| Allworth Financial LP | 0.00% | Reduce -71.0% | 1,278 | $5K |
| NewEdge Advisors, LLC | 0.00% | No change | 1,000 | $4K |
| Arax Advisory Partners | 0.00% | Add +317.8% | 961 | $4K |
| GAMMA Investing LLC | 0.00% | Reduce -9.4% | 586 | $2K |
| SBI Securities Co., Ltd. | 0.00% | Add +48.3% | 580 | $2K |
| Quarry LP | 0.00% | New | 540 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -84.5% | 536 | $2K |
| Fairman Group, LLC | 0.00% | No change | 500 | $2K |
| Rothschild Investment LLC | 0.00% | Add +0.5% | 384 | $1K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 319 | $1K |
| Fortitude Family Office, LLC | 0.00% | Reduce -29.4% | 308 | $1K |
| Basecamp Wealth Advisors LLC | 0.00% | Add +1.7% | 292 | $1K |
| Parkside Financial Bank & Trust | 0.00% | No change | 285 | $1K |
| Optiver Holding B.V. | 0.00% | Reduce -70.8% | 260 | $959 |
| Eastern Bank | 0.00% | New | 134 | $494 |
| Sachetta, LLC | 0.00% | New | 100 | $369 |
| Harbour Investments, Inc. | 0.00% | Add +5.4% | 78 | $288 |
| Farther Finance Advisors, LLC | 0.00% | Reduce -64.3% | 55 | $203 |
| Natixis | 0.00% | New | 45 | $166 |
| NFSG Corp | 0.00% | No change | 45 | $166 |
| National Bank of Canada | 0.00% | Add +320.0% | 42 | $155 |
| Essential Partners LLC | 0.00% | Reduce -97.3% | 27 | $100 |
| IFP Advisors, Inc | 0.00% | Add +1050.0% | 23 | $85 |
| Clearstead Advisors, LLC | 0.00% | New | 9 | $34 |
| Wealth Enhancement Trust Services, Inc. | 0.00% | New | 3 | $11 |
| Covestor Ltd | 0.00% | Add +238.7% | 105 | $0 |
"% of holder's portfolio" is PRME's weight in each manager's 13F, not the share of Prime Medicine Inc. the manager owns.