Prothena Corp.PRTA
13F holders, Q4 2025 (December 31)182holders −5
22new positions
25sold out
7famous investors
$9.56avg. 13F price*
At the end of Q4 2025, 182 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, down 5 from Q3 2025. 22 opened new positions and 25 sold out. The largest holders were FMR LLC ($72.1M), BlackRock, Inc. ($39.2M) and Rubric Capital Management LP ($35.1M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Prothena Corp. PLC
- CUSIP
- G72800108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 22 | $6.9M |
| Exits | 25 | $10.4M |
All 13F filers, Q3 2025 → Q4 2025: 9,206,591 shares bought and 4,390,948 shares sold, net +4,815,643 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 182 holders
| FMR LLC | 0.00% | Reduce -4.4% | 7,551,218 | $72.1M |
| BlackRock, Inc. | 0.00% | Add +14.2% | 4,107,459 | $39.2M |
| Rubric Capital Management LP | 0.42% | Add +138.7% | 3,677,331 | $35.1M |
| State Street Corp. | 0.00% | Add +151.7% | 2,267,802 | $21.7M |
| Vanguard Group Inc. | 0.00% | Add +4.4% | 2,140,909 | $20.4M |
| D. E. Shaw & Co. | 0.01% | Add +27.8% | 1,681,369 | $16.1M |
| Armistice Capital, LLC | 0.35% | Reduce -17.8% | 1,500,000 | $14.3M |
| ADAR1 Capital Management, LLC | 1.04% | Reduce -0.8% | 1,457,764 | $13.9M |
| Acadian Asset Management LLC | 0.02% | Add +16.0% | 1,437,358 | $13.7M |
| Palo Alto Investors LP | 1.76% | Reduce -0.3% | 1,320,510 | $12.6M |
| Morgan Stanley | 0.00% | Add +55.9% | 1,246,775 | $11.9M |
| Geode Capital Management, LLC | 0.00% | Add +4.3% | 1,063,069 | $10.2M |
| Jacobs Levy Equity Management, Inc. | 0.04% | Add +11.6% | 978,011 | $9.3M |
| Federated Hermes, Inc. | 0.02% | Add +40.6% | 974,367 | $9.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +164.8% | 935,333 | $8.9M |
| Citadel Advisors | 0.01% | Add +18.9% | 912,382 | $8.7M |
| Point72 Asset Management | 0.01% | Add +33.0% | 860,018 | $8.2M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -3.9% | 775,207 | $7.4M |
| Nuveen, LLC | 0.00% | Add +13.6% | 759,107 | $7.2M |
| Two Sigma Investments, LP | 0.01% | Add +57.1% | 670,138 | $6.4M |
| Mariner, LLC | 0.01% | Reduce -2.2% | 577,938 | $5.5M |
| Rangeley Capital, LLC | 4.38% | Reduce -6.4% | 524,600 | $5.0M |
| Birchview Capital, LP | 2.47% | Reduce -19.7% | 441,019 | $4.2M |
| Renaissance Technologies | 0.01% | Add +17.3% | 435,515 | $4.2M |
| Jane Street Group, LLC | 0.00% | Reduce -30.8% | 428,651 | $4.1M |
| Two Sigma Advisers, LP | 0.01% | Add +60.9% | 427,400 | $4.1M |
| Bank of America Corp. | 0.00% | Add +54.2% | 427,360 | $4.1M |
| UBS Group AG | 0.00% | Add +6.4% | 426,360 | $4.1M |
| BNP Paribas Financial Markets | 0.00% | Add +85.9% | 423,955 | $4.0M |
| Qube Research & Technologies Ltd | 0.01% | Add +60.4% | 407,689 | $3.9M |
| Northern Trust Corp. | 0.00% | Add +8.5% | 363,241 | $3.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.9% | 357,335 | $3.4M |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -54.4% | 298,101 | $2.8M |
| Man Group plc | 0.01% | Add +104.2% | 269,513 | $2.6M |
| Monimus Capital Management, LP | 1.60% | Reduce -1.5% | 254,122 | $2.4M |
| Jump Financial, LLC | 0.03% | Add +27.7% | 237,828 | $2.3M |
| Squarepoint Ops LLC | 0.00% | Add +71.6% | 218,041 | $2.1M |
| DCF Advisers, LLC | 0.62% | Reduce -2.5% | 195,747 | $1.9M |
| AQR Capital Management | 0.00% | Reduce -12.9% | 186,785 | $1.8M |
| Barclays PLC | 0.00% | Add +87.2% | 183,625 | $1.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -76.9% | 169,955 | $1.6M |
| Walleye Capital LLC | 0.01% | Add +247574.6% | 156,035 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -13.7% | 132,700 | $1.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 125,890 | $1.2M |
| Focused Wealth Management, Inc | 0.11% | Add +88.1% | 107,479 | $1.0M |
| Diadema Partners LP | 0.61% | New | 106,539 | $1.0M |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.1% | 105,441 | $1.0M |
| Los Angeles Capital Management LLC | 0.00% | Reduce -20.1% | 95,406 | $1000K |
| Quantinno Capital Management LP | 0.00% | Add +2.4% | 103,618 | $990K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +725.8% | 100,510 | $960K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -22.2% | 99,350 | $949K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 94,155 | $899K |
| Hennion & Walsh Asset Management, Inc. | 0.03% | Add +7.9% | 91,284 | $872K |
| ExodusPoint Capital Management, LP | 0.01% | Add +190.8% | 87,990 | $840K |
| Rafferty Asset Management, LLC | 0.00% | New | 82,553 | $788K |
| T. Rowe Price Associates Inc. | 0.00% | Add +3.8% | 81,515 | $779K |
| American Century Companies Inc. | 0.00% | Add +9.1% | 78,804 | $753K |
| Assenagon Asset Management S.A. | 0.00% | Reduce -14.4% | 76,769 | $733K |
| Alliancebernstein L.P. | 0.00% | No change | 69,607 | $665K |
| Duncan Williams Asset Management, LLC | 0.16% | Reduce -20.4% | 70,281 | $625K |
| Martingale Asset Management L P | 0.02% | New | 63,453 | $606K |
| SG Americas Securities, LLC | 0.00% | Add +11.1% | 63,018 | $602K |
| Pinnacle Associates Ltd. | 0.01% | Reduce -12.0% | 62,724 | $599K |
| Creative Planning | 0.00% | Reduce -3.4% | 61,969 | $592K |
| Caption Management, LLC | 0.03% | No change | 61,009 | $583K |
| Wells Fargo & Company | 0.00% | Add +48.7% | 60,108 | $574K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | Add +103.1% | 58,853 | $562K |
| Rhumbline Advisers | 0.00% | Reduce -8.9% | 56,527 | $540K |
| XTX Topco Ltd | 0.01% | Add +247.2% | 54,881 | $524K |
| Marshall Wace, LLP | 0.00% | New | 54,778 | $523K |
| Quinn Opportunity Partners LLC | 0.02% | No change | 50,000 | $478K |
| Franklin Resources Inc. | 0.00% | Reduce -22.8% | 47,251 | $451K |
| Massachusetts Financial Services Co. | 0.00% | Reduce -3.2% | 45,970 | $439K |
| Seven Fleet Capital Management LP | 0.28% | — | 43,300 | $414K |
| Public Employees Retirement System of Ohio | 0.00% | No change | 42,158 | $403K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 14,000 | $383K |
| Deutsche Bank AG | 0.00% | Add +5.1% | 35,482 | $339K |
| Quadrature Capital Ltd | 0.00% | Add +14.2% | 31,090 | $297K |
| Profund Advisors LLC | 0.01% | New | 30,616 | $292K |
| RBF Capital, LLC | 0.01% | No change | 29,200 | $279K |
| Persistent Asset Partners Ltd | 0.13% | New | 28,589 | $273K |
| PNC Financial Services Group, Inc. | 0.00% | Add +55.1% | 28,128 | $269K |
| Graham Capital Management, L.P. | 0.01% | Reduce -48.0% | 27,756 | $265K |
| HSBC Holdings PLC | 0.00% | Reduce -25.9% | 27,733 | $261K |
| Invesco Ltd. | 0.00% | Reduce -15.0% | 26,609 | $254K |
| Tudor Investment Corporation | 0.00% | Reduce -2.2% | 26,473 | $253K |
| Gsa Capital Partners LLP | 0.02% | New | 26,354 | $252K |
| Virtus Investment Advisers, LLC | 0.07% | Add +14.4% | 25,679 | $245K |
| MetLife Investment Management, LLC | 0.00% | Add +31.7% | 25,501 | $244K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +34.0% | 25,240 | $240K |
| Purkiss Capital Advisors LLC | 0.11% | Reduce -1.2% | 25,086 | $240K |
| Edgewood Management LLC | 0.00% | No change | 24,060 | $230K |
| Polymer Capital Management (US) LLC | 0.03% | New | 23,513 | $225K |
| Headlands Technologies LLC | 0.02% | New | 23,352 | $223K |
| Millennium Management | 0.00% | Reduce -96.5% | 21,976 | $210K |
| Covestor Ltd | 0.11% | Reduce -30.7% | 21,793 | $208K |
| Mogy Joel R Investment Counsel Inc. | 0.01% | No change | 20,750 | $198K |
| Intech Investment Management LLC | 0.00% | Add +6.3% | 20,601 | $197K |
| Trexquant Investment LP | 0.00% | Reduce -93.0% | 19,384 | $185K |
| Ballentine Partners, LLC | 0.00% | Reduce -1.3% | 18,070 | $173K |
| STRS Ohio | 0.00% | Reduce -38.9% | 17,600 | $168K |
| Atom Investors LP | 0.01% | Reduce -20.1% | 17,026 | $163K |
| Entropy Technologies, LP | 0.01% | New | 16,900 | $161K |
| Raymond James Financial Inc. | 0.00% | Reduce -25.2% | 16,483 | $157K |
| Susquehanna International Group, LLP | 0.00% | Reduce -89.8% | 15,975 | $153K |
| Chicago Partners Investment Group LLC | 0.00% | Add +2.6% | 15,222 | $152K |
| Jones Financial Companies LLLP | 0.00% | Add +13.6% | 15,900 | $152K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,386 | $147K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -1.2% | 13,695 | $131K |
| Great Lakes Advisors, LLC | 0.00% | Reduce -0.7% | 13,189 | $126K |
| Cary Street Partners Financial LLC | 0.00% | No change | 12,500 | $119K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Reduce -0.1% | 12,453 | $119K |
| Citigroup Inc. | 0.00% | Add +242.9% | 12,318 | $118K |
| Brooklyn Investment Group | 0.01% | Add +8.4% | 12,047 | $114K |
| DRW Securities, LLC | 0.01% | New | 11,955 | $114K |
| PDT Partners, LLC | 0.01% | New | 11,334 | $108K |
| Inscription Capital, LLC | 0.01% | Add +1.6% | 10,652 | $102K |
| ProShare Advisors LLC | 0.00% | New | 10,425 | $100K |
| Cwm, LLC | 0.00% | Reduce -1.5% | 10,095 | $96K |
| Fox Run Management, L.L.C. | 0.01% | Reduce -77.3% | 10,045 | $96K |
| New York State Common Retirement Fund | 0.00% | No change | 8,979 | $86K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -7.0% | 8,772 | $84K |
| Canada Pension Plan Investment Board | 0.00% | New | 7,100 | $68K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,552 | $63K |
| Pinnacle Wealth Planning Services, Inc. | 0.01% | New | 5,668 | $54K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 5,000 | $48K |
| Rockefeller Capital Management L.P. | 0.00% | Add +4.2% | 4,590 | $44K |
| Royal Bank of Canada | 0.00% | Reduce -57.1% | 4,427 | $42K |
| Legal & General Group Plc | 0.00% | Add +12.4% | 4,044 | $39K |
| Signaturefd, LLC | 0.00% | Reduce -1.7% | 3,609 | $34K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,428 | $33K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +119.9% | 2,826 | $27K |
| California State Teachers Retirement System | 0.00% | Add +12.2% | 2,710 | $26K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +25.7% | 2,616 | $25K |
| Farther Finance Advisors, LLC | 0.00% | No change | 2,434 | $23K |
| Sterling Capital Management LLC | 0.00% | Reduce -8.6% | 2,327 | $22K |
| Versant Capital Management, Inc | 0.00% | No change | 2,044 | $20K |
| Simplex Trading, LLC | 0.00% | Reduce -95.4% | 1,927 | $18K |
| Flagship Wealth Advisors, LLC | 0.00% | No change | 1,500 | $14K |
| Amalgamated Bank | 0.00% | Reduce -4.0% | 1,383 | $13K |
| Quadrant Capital Group LLC | 0.00% | No change | 1,260 | $12K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.5% | 1,057 | $10K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,000 | $10K |
| HighMark Wealth Management LLC | 0.00% | Reduce -55.2% | 900 | $9K |
| Allworth Financial LP | 0.00% | Add +2.3% | 885 | $8K |
| Torren Management, LLC | 0.00% | — | 884 | $8K |
| HM Payson & Co. | 0.00% | No change | 600 | $6K |
| GAMMA Investing LLC | 0.00% | Add +32.1% | 510 | $5K |
| US Bancorp \de | 0.00% | Add +14.3% | 359 | $3K |
| Essential Partners LLC | 0.00% | No change | 333 | $3K |
| Optiver Holding B.V. | 0.00% | Reduce -15.9% | 296 | $3K |
| Osaic Holdings, Inc. | 0.00% | Reduce -2.5% | 237 | $2K |
| Daiwa Securities Group Inc. | 0.00% | No change | 195 | $2K |
| Evelyn Partners Investment Management LLP | 0.00% | No change | 199 | $2K |
| Basecamp Wealth Advisors LLC | 0.00% | — | 197 | $2K |
| Asset Dedication, LLC | 0.00% | No change | 184 | $2K |
| Parallel Advisors, LLC | 0.00% | No change | 179 | $2K |
| Sittner & Nelson, LLC | 0.00% | Add +19.4% | 185 | $2K |
| Johnson Financial Group, Inc. | 0.00% | No change | 151 | $1K |
| Albion Financial Group | 0.00% | No change | 125 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -81.1% | 112 | $1K |
| True Wealth Design, LLC | 0.00% | No change | 103 | $984 |
| Gould Capital, LLC | 0.00% | No change | 100 | $955 |
| Harbor Investment Advisory, LLC | 0.00% | No change | 100 | $955 |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 90 | $860 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 71 | $678 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +8.0% | 54 | $516 |
| CIBC Private Wealth Group LLC | 0.00% | No change | 48 | $458 |
| Blue Trust, Inc. | 0.00% | No change | 33 | $315 |
| Larson Financial Group LLC | 0.00% | Add +333.3% | 26 | $248 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 23 | $220 |
| CoreCap Advisors, LLC | 0.00% | No change | 23 | $220 |
| IFP Advisors, Inc | 0.00% | No change | 15 | $143 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -48.3% | 15 | $143 |
| Arax Advisory Partners | 0.00% | Reduce -99.8% | 13 | $124 |
| Key Financial Inc | 0.00% | No change | 12 | $115 |
| Clearstead Advisors, LLC | 0.00% | Reduce -52.4% | 10 | $96 |
| MAI Capital Management | 0.00% | New | 10 | $96 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 6 | $57 |
| Harbour Investments, Inc. | 0.00% | No change | 1 | $10 |
| New Millennium Group LLC | 0.00% | New | 1 | $10 |
| Resources Management Corp. /CT/ | 0.00% | New | 3 | $0 |
"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.