Taysha Gene TherapiesTSHA
13F holders, Q1 2025 (March 31)127holders −4
21new positions
25sold out
4famous investors
$1.39avg. 13F price*
At the end of Q1 2025, 127 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, down 4 from Q4 2024. 21 opened new positions and 25 sold out. The largest holders were Avoro Capital Advisors LLC ($27.8M), RTW Investments, LP ($26.1M) and Morgan Stanley ($23.4M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $8.9M |
| Exits | 25 | $22.0M |
All 13F filers, Q4 2024 → Q1 2025: 21,368,284 shares bought and 21,988,910 shares sold, net −620,626 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 127 holders
| Avoro Capital Advisors LLC | 0.43% | No change | 19,999,999 | $27.8M |
| RTW Investments, LP | 0.40% | Add +116.6% | 18,787,866 | $26.1M |
| Morgan Stanley | 0.00% | Reduce -4.5% | 16,846,374 | $23.4M |
| FMR LLC | 0.00% | Reduce -4.5% | 15,631,954 | $21.7M |
| BlackRock, Inc. | 0.00% | Add +0.4% | 13,589,178 | $18.9M |
| Ra Capital Management, L.P. | 0.25% | No change | 10,872,503 | $15.1M |
| Octagon Capital Advisors LP | 3.23% | Add +2.4% | 10,700,000 | $14.9M |
| Vanguard Group Inc. | 0.00% | Reduce -1.5% | 8,770,921 | $12.2M |
| Siren, L.L.C. | 0.51% | Reduce -1.3% | 6,514,737 | $9.1M |
| Point72 Asset Management | 0.02% | New | 4,569,678 | $6.4M |
| Baker Bros. Advisors LP | 0.06% | No change | 4,004,756 | $5.6M |
| Tybourne Capital Management (hk) Ltd. | 21.83% | No change | 3,700,000 | $5.1M |
| Geode Capital Management, LLC | 0.00% | Add +2.6% | 3,664,732 | $5.1M |
| State Street Corp. | 0.00% | Reduce -50.1% | 3,233,512 | $4.5M |
| Polar Capital Holdings Plc | 0.03% | No change | 3,000,000 | $4.2M |
| Millennium Management | 0.00% | Add +1069.2% | 1,772,654 | $2.5M |
| Granahan Investment Management, LLC | 0.11% | Add +0.3% | 1,640,793 | $2.3M |
| Northern Trust Corp. | 0.00% | Reduce -1.9% | 1,431,666 | $2.0M |
| Palo Alto Investors LP | 0.38% | Add +75.0% | 1,419,468 | $2.0M |
| B Group, Inc. | 1.52% | Add +30.0% | 1,255,556 | $1.7M |
| ADAR1 Capital Management, LLC | 0.29% | Add +500.0% | 1,066,309 | $1.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -62.1% | 1,003,067 | $1.4M |
| Woodline Partners LP | 0.01% | Reduce -16.5% | 858,254 | $1.2M |
| Quantum Private Wealth, LLC | 0.42% | Reduce -0.4% | 791,476 | $1.1M |
| Superstring Capital Management LP | 1.25% | New | 755,599 | $1.1M |
| Sands Capital Alternatives, LLC | 0.25% | No change | 724,873 | $1.0M |
| Barclays PLC | 0.00% | Add +111.5% | 708,966 | $985K |
| Alphabet Inc. | 0.06% | No change | 640,882 | $891K |
| Bank of America Corp. | 0.00% | Reduce -62.8% | 636,842 | $885K |
| Wellington Management Group LLP | 0.00% | Add +6.8% | 625,198 | $869K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +15.4% | 547,128 | $761K |
| Nuveen, LLC | 0.00% | — | 546,414 | $760K |
| DAFNA Capital Management LLC | 0.21% | No change | 522,500 | $726K |
| Bank of New York Mellon Corp | 0.00% | Add +0.7% | 453,420 | $630K |
| UBS Group AG | 0.00% | Reduce -0.8% | 418,132 | $581K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -62.9% | 359,007 | $499K |
| NorthCoast Asset Management LLC | 0.00% | No change | 292,778 | $407K |
| Jefferies Financial Group Inc. | 0.01% | New | 245,254 | $341K |
| Susquehanna International Group, LLP | 0.00% | Add +59.7% | 227,472 | $316K |
| Citadel Advisors | 0.00% | Reduce -70.9% | 216,611 | $301K |
| Rhumbline Advisers | 0.00% | Add +7.0% | 205,462 | $286K |
| XTX Topco Ltd | 0.01% | New | 203,129 | $282K |
| Invesco Ltd. | 0.00% | Add +83.0% | 159,899 | $222K |
| Chicago Partners Investment Group LLC | 0.01% | Add +0.5% | 116,565 | $221K |
| Los Angeles Capital Management LLC | 0.00% | Add +3.9% | 142,810 | $199K |
| HRT Financial LP | 0.00% | New | 139,692 | $194K |
| EntryPoint Capital, LLC | 0.09% | Add +121.0% | 135,897 | $189K |
| Privium Fund Management B.V. | 0.05% | No change | 134,900 | $188K |
| Deutsche Bank AG | 0.00% | Reduce -11.0% | 134,418 | $187K |
| Citigroup Inc. | 0.00% | Reduce -47.4% | 133,194 | $185K |
| BIT Capital GmbH | 0.02% | New | 117,062 | $163K |
| Franklin Resources Inc. | 0.00% | New | 116,238 | $162K |
| Wells Fargo & Company | 0.00% | Add +5.5% | 109,048 | $152K |
| Alliancebernstein L.P. | 0.00% | No change | 108,250 | $150K |
| AQR Capital Management | 0.00% | Add +325.6% | 107,899 | $150K |
| MetLife Investment Management, LLC | 0.00% | Add +71.0% | 107,711 | $150K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -5.1% | 103,074 | $143K |
| Intech Investment Management LLC | 0.00% | Add +46.9% | 99,912 | $139K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 85,878 | $119K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 83,864 | $117K |
| Leonteq Securities AG | 0.01% | No change | 79,999 | $111K |
| Creative Planning | 0.00% | Add +276.8% | 78,335 | $109K |
| T. Rowe Price Associates Inc. | 0.00% | Add +13.3% | 74,025 | $103K |
| Virtus Investment Advisers, LLC | 0.03% | New | 72,957 | $101K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +1.3% | 63,797 | $89K |
| Commonwealth Equity Services, LLC | 0.00% | Add +1.7% | 60,069 | $83K |
| Mariner, LLC | 0.00% | Add +0.3% | 58,490 | $81K |
| Voya Investment Management LLC | 0.00% | Reduce -5.1% | 48,616 | $68K |
| ProShare Advisors LLC | 0.00% | Reduce -20.1% | 47,195 | $66K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 45,678 | $63K |
| Jain Global LLC | 0.00% | New | 45,200 | $63K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.4% | 41,120 | $57K |
| Williams & Novak, LLC | 0.06% | No change | 45,000 | $57K |
| Cibc World Markets Corp. | 0.00% | Add +137.1% | 38,897 | $54K |
| First Manhattan Co. Llc. | 0.00% | No change | 28,500 | $40K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 23,490 | $33K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.7% | 22,844 | $32K |
| State Board of Administration of Florida Retirement System | 0.00% | Add +13.4% | 22,700 | $32K |
| New York State Common Retirement Fund | 0.00% | No change | 21,100 | $29K |
| Lee Financial Co | 0.00% | No change | 20,000 | $28K |
| Legal & General Group Plc | 0.00% | Reduce -0.3% | 19,958 | $28K |
| HSBC Holdings PLC | 0.00% | Reduce -0.7% | 20,257 | $28K |
| Victory Capital Management Inc. | 0.00% | Add +0.1% | 19,017 | $26K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 15,672 | $22K |
| Point72 (DIFC) Ltd | 0.00% | New | 15,528 | $22K |
| Prudential Financial Inc. | 0.00% | Add +16.6% | 15,140 | $21K |
| Howard Capital Management, LLC | 0.00% | No change | 14,165 | $20K |
| Principal Financial Group Inc. | 0.00% | Reduce -6.6% | 13,989 | $19K |
| Two Sigma Securities, LLC | 0.00% | New | 13,071 | $18K |
| Xponance LLC | 0.00% | Add +6.0% | 12,639 | $18K |
| California State Teachers Retirement System | 0.00% | No change | 12,635 | $18K |
| Marex Group Ltd | 0.00% | No change | 12,500 | $17K |
| BNP Paribas Financial Markets | 0.00% | Reduce -48.2% | 12,241 | $17K |
| SIH Partners, LLLP | 0.00% | New | 12,173 | $17K |
| Catalyst Funds Management Pty Ltd | 0.00% | New | 11,900 | $17K |
| Camelot Portfolios, LLC | 0.01% | New | 11,000 | $15K |
| Cwm, LLC | 0.00% | Add +3872.4% | 10,527 | $15K |
| Bordeaux Wealth Advisors LLC | 0.00% | New | 10,109 | $14K |
| Capital Investment Advisors, LLC | 0.00% | No change | 10,000 | $14K |
| Mackenzie Financial Corp. | 0.00% | No change | 10,000 | $14K |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.