Taysha Gene TherapiesTSHA
13F holders, Q4 2024 (December 31)131holders +12
23new positions
15sold out
4famous investors
$1.73avg. 13F price*
At the end of Q4 2024, 131 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, up 12 from Q3 2024. 23 opened new positions and 15 sold out. The largest holders were Avoro Capital Advisors LLC ($34.6M), Morgan Stanley ($30.5M) and FMR LLC ($28.3M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $15.2M |
| Exits | 15 | $3.6M |
All 13F filers, Q3 2024 → Q4 2024: 34,834,000 shares bought and 23,212,839 shares sold, net +11,621,161 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 131 holders
| Avoro Capital Advisors LLC | 0.49% | Add +7.2% | 19,999,999 | $34.6M |
| Morgan Stanley | 0.00% | Add +130.2% | 17,640,366 | $30.5M |
| FMR LLC | 0.00% | Reduce -12.4% | 16,365,664 | $28.3M |
| BlackRock, Inc. | 0.00% | Add +0.1% | 13,531,467 | $23.4M |
| Ra Capital Management, L.P. | 0.25% | No change | 10,872,503 | $18.8M |
| Octagon Capital Advisors LP | 3.08% | Add +128.6% | 10,450,000 | $18.1M |
| Vanguard Group Inc. | 0.00% | Add +7.8% | 8,906,764 | $15.4M |
| RTW Investments, LP | 0.23% | Reduce -42.0% | 8,672,630 | $15.0M |
| Siren, L.L.C. | 0.50% | Add +35.3% | 6,602,475 | $11.4M |
| State Street Corp. | 0.00% | Add +86.6% | 6,474,367 | $11.2M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | New | 5,000,000 | $8.7M |
| Baker Bros. Advisors LP | 0.07% | No change | 4,004,756 | $6.9M |
| Tybourne Capital Management (hk) Ltd. | 1.61% | No change | 3,700,000 | $6.4M |
| Geode Capital Management, LLC | 0.00% | Add +0.3% | 3,572,349 | $6.2M |
| Venrock Adviser, LLC | 0.38% | Reduce -64.2% | 3,225,180 | $5.6M |
| Polar Capital Holdings Plc | 0.03% | Reduce -0.8% | 3,000,000 | $5.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -11.9% | 2,643,755 | $4.6M |
| Bank of America Corp. | 0.00% | Add +1178.9% | 1,710,303 | $3.0M |
| Granahan Investment Management, LLC | 0.12% | Add +43.5% | 1,636,381 | $2.8M |
| Norges Bank | 0.00% | New | 1,461,120 | $2.5M |
| Northern Trust Corp. | 0.00% | Add +6.3% | 1,458,732 | $2.5M |
| Woodline Partners LP | 0.01% | Add +0.0% | 1,027,522 | $1.8M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -19.8% | 967,144 | $1.7M |
| B Group, Inc. | 1.02% | — | 965,556 | $1.7M |
| Acuta Capital Partners, LLC | 1.54% | Reduce -58.3% | 884,244 | $1.5M |
| Renaissance Technologies | 0.00% | New | 878,448 | $1.5M |
| Palo Alto Investors LP | 0.22% | No change | 811,268 | $1.4M |
| Quantum Private Wealth, LLC | 0.44% | Add +3.6% | 794,976 | $1.4M |
| Citadel Advisors | 0.00% | Reduce -73.9% | 745,205 | $1.3M |
| Sands Capital Alternatives, LLC | 0.27% | No change | 724,873 | $1.3M |
| Alphabet Inc. | 0.06% | No change | 640,882 | $1.1M |
| Wellington Management Group LLP | 0.00% | Add +26.4% | 585,594 | $1.0M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -3.6% | 546,414 | $945K |
| DAFNA Capital Management LLC | 0.23% | New | 522,500 | $904K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.5% | 474,257 | $820K |
| Bank of New York Mellon Corp | 0.00% | Add +33.1% | 450,261 | $779K |
| UBS Group AG | 0.00% | Add +358.0% | 421,396 | $729K |
| Barclays PLC | 0.00% | Add +35.6% | 335,238 | $587K |
| NorthCoast Asset Management LLC | 0.00% | No change | 292,778 | $507K |
| Citigroup Inc. | 0.00% | Add +91.0% | 253,292 | $438K |
| Rafferty Asset Management, LLC | 0.00% | New | 252,257 | $436K |
| Squarepoint Ops LLC | 0.00% | Add +105.4% | 211,842 | $366K |
| Rhumbline Advisers | 0.00% | Add +3.1% | 192,079 | $332K |
| ADAR1 Capital Management, LLC | 0.07% | Reduce -29.3% | 177,707 | $307K |
| Jane Street Group, LLC | 0.00% | Add +57.6% | 169,575 | $293K |
| Millennium Management | 0.00% | New | 151,614 | $262K |
| Deutsche Bank AG | 0.00% | Reduce -94.1% | 151,083 | $261K |
| Susquehanna International Group, LLP | 0.00% | Reduce -19.3% | 142,463 | $246K |
| Marshall Wace, LLP | 0.00% | Reduce -71.6% | 138,111 | $239K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -33.6% | 137,460 | $238K |
| Privium Fund Management B.V. | 0.05% | Add +12.4% | 134,900 | $233K |
| Chicago Partners Investment Group LLC | 0.01% | Reduce -1.8% | 116,044 | $224K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +23.3% | 108,604 | $188K |
| Alliancebernstein L.P. | 0.00% | No change | 108,250 | $187K |
| Virtu Financial LLC | 0.01% | New | 107,544 | $186K |
| Wells Fargo & Company | 0.00% | Add +43.7% | 103,384 | $179K |
| Invesco Ltd. | 0.00% | Add +1.9% | 87,355 | $151K |
| Corebridge Financial, Inc. | 0.00% | Reduce -5.4% | 87,150 | $151K |
| Leonteq Securities AG | 0.01% | Reduce 0.0% | 79,999 | $138K |
| Aquatic Capital Management LLC | 0.00% | New | 78,246 | $135K |
| Intech Investment Management LLC | 0.00% | Add +61.6% | 68,035 | $118K |
| T. Rowe Price Associates Inc. | 0.00% | Add +9.4% | 65,331 | $114K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +3.9% | 63,011 | $109K |
| MetLife Investment Management, LLC | 0.00% | Reduce -17.2% | 62,990 | $109K |
| EntryPoint Capital, LLC | 0.04% | Add +127.5% | 61,495 | $106K |
| LPL Financial LLC | 0.00% | New | 60,000 | $104K |
| ProShare Advisors LLC | 0.00% | Add +32.3% | 59,076 | $102K |
| Commonwealth Equity Services, LLC | 0.00% | Add +110.4% | 59,069 | $102K |
| Mariner, LLC | 0.00% | Add +337.5% | 58,342 | $101K |
| Voya Investment Management LLC | 0.00% | Reduce -7.0% | 51,216 | $89K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +268.8% | 51,085 | $88K |
| Profund Advisors LLC | 0.00% | New | 50,242 | $87K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 45,678 | $79K |
| Williams & Novak, LLC | 0.08% | No change | 45,000 | $78K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +10.3% | 43,456 | $75K |
| Engineers Gate Manager LP | 0.00% | New | 35,808 | $62K |
| Verition Fund Management LLC | 0.00% | New | 34,098 | $59K |
| Virtus Advisers, LLC | 0.02% | Add +43.0% | 31,597 | $55K |
| First Manhattan Co. Llc. | 0.00% | New | 28,500 | $49K |
| SG Americas Securities, LLC | 0.00% | Reduce -55.5% | 28,498 | $49K |
| AQR Capital Management | 0.00% | Reduce -63.5% | 25,354 | $44K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -0.1% | 23,490 | $41K |
| BNP Paribas Financial Markets | 0.00% | New | 23,644 | $41K |
| Ameriprise Financial Inc. | 0.00% | New | 22,993 | $40K |
| Axq Capital, LP | 0.02% | New | 22,432 | $39K |
| New York State Common Retirement Fund | 0.00% | No change | 21,100 | $37K |
| Creative Planning | 0.00% | Add +47.2% | 20,788 | $36K |
| HSBC Holdings PLC | 0.00% | Add +65.6% | 20,391 | $36K |
| Legal & General Group Plc | 0.00% | No change | 20,018 | $35K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 20,010 | $35K |
| Lee Financial Co | 0.00% | No change | 20,000 | $35K |
| Victory Capital Management Inc. | 0.00% | Reduce -5.0% | 19,001 | $33K |
| E Fund Management Co., Ltd. | 0.00% | New | 17,844 | $31K |
| Cibc World Markets Corp. | 0.00% | New | 16,405 | $28K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 15,672 | $27K |
| Principal Financial Group Inc. | 0.00% | Reduce -5.2% | 14,971 | $26K |
| Ground Swell Capital, LLC | 0.06% | New | 14,660 | $25K |
| Howard Capital Management, LLC | 0.00% | No change | 14,165 | $25K |
| Prudential Financial Inc. | 0.00% | Add +16.1% | 12,990 | $22K |
| California State Teachers Retirement System | 0.00% | No change | 12,635 | $22K |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.