Taysha Gene TherapiesTSHA
13F holders, Q1 2026 (March 31)191holders −4
26new positions
33sold out
7famous investors
$4.54avg. 13F price*
At the end of Q1 2026, 191 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, down 4 from Q4 2025. 26 opened new positions and 33 sold out. The largest holders were Ra Capital Management, L.P. ($105.3M), Goldman Sachs Group Inc. ($100.0M) and Avoro Capital Advisors LLC ($97.0M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 26 | $3.5M |
| Exits | 33 | $32.0M |
All 13F filers, Q4 2025 → Q1 2026: 24,353,068 shares bought and 26,259,720 shares sold, net −1,906,652 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 191 holders
| Ra Capital Management, L.P. | 1.12% | No change | 23,555,648 | $105.3M |
| Goldman Sachs Group Inc. | 0.01% | Add +63.4% | 22,369,645 | $100.0M |
| Avoro Capital Advisors LLC | 0.96% | No change | 21,700,000 | $97.0M |
| BlackRock, Inc. | 0.00% | Reduce -1.5% | 18,365,608 | $82.1M |
| Vestal Point Capital, LP | 2.25% | Add +30.9% | 18,000,000 | $80.5M |
| Morgan Stanley | 0.00% | Reduce -0.6% | 17,965,371 | $80.3M |
| FMR LLC | 0.00% | Add +5.9% | 14,321,255 | $64.0M |
| RTW Investments, LP | 0.61% | Reduce -16.6% | 13,680,248 | $61.2M |
| State Street Corp. | 0.00% | Add +3.9% | 11,209,078 | $50.1M |
| Vanguard Capital Management LLC | 0.00% | — | 10,231,502 | $45.7M |
| Octagon Capital Advisors LP | 4.38% | No change | 8,859,911 | $39.6M |
| Siren, L.L.C. | 1.09% | Reduce -12.8% | 8,829,913 | $39.5M |
| Polar Capital Holdings Plc | 0.11% | Reduce -28.7% | 5,654,340 | $25.3M |
| Geode Capital Management, LLC | 0.00% | Add +2.7% | 5,531,955 | $24.7M |
| GordonMD Global Investments LP | 15.47% | Reduce -44.6% | 737,550 | $22.2M |
| D. E. Shaw & Co. | 0.02% | Add +10.3% | 4,427,301 | $19.8M |
| Baker Bros. Advisors LP | 0.10% | No change | 4,004,756 | $17.9M |
| Millennium Management | 0.01% | Add +3.2% | 3,281,820 | $14.7M |
| Casdin Capital, LLC | 1.10% | Add +116.7% | 3,250,000 | $14.5M |
| ADAR1 Capital Management, LLC | 0.81% | Add +19.4% | 2,979,429 | $13.3M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.02% | Reduce -22.5% | 2,883,301 | $12.9M |
| Deerfield Management Company, L.P. | 0.17% | No change | 2,722,165 | $12.2M |
| Barclays PLC | 0.00% | Reduce -49.2% | 2,812,010 | $11.4M |
| SG Americas Securities, LLC | 0.01% | Add +178.5% | 2,176,742 | $9.7M |
| Vanguard Portfolio Management LLC | 0.00% | — | 2,022,498 | $9.0M |
| Rice Hall James & Associates, LLC | 0.48% | Add +53.0% | 1,944,671 | $8.7M |
| Northern Trust Corp. | 0.00% | Add +46.5% | 1,814,318 | $8.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -5.0% | 1,808,599 | $8.1M |
| B Group, Inc. | 5.97% | No change | 1,800,556 | $8.0M |
| Bank of America Corp. | 0.00% | Add +45.5% | 1,677,046 | $7.5M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 1,530,461 | $6.8M |
| Palo Alto Investors LP | 0.95% | Add +17.6% | 1,391,382 | $6.2M |
| Aberdeen Group plc | 0.01% | No change | 1,021,063 | $4.6M |
| Affinity Asset Advisors, LLC | 0.27% | Reduce -69.7% | 1,000,000 | $4.5M |
| Granahan Investment Management, LLC | 0.19% | Add +25.5% | 883,241 | $3.9M |
| Quantum Private Wealth, LLC | 1.17% | Add +3.6% | 849,212 | $3.8M |
| Two Sigma Investments, LP | 0.00% | Add +111.3% | 742,081 | $3.3M |
| Sands Capital Alternatives, LLC | 0.77% | No change | 724,873 | $3.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -2.5% | 754,782 | $3.1M |
| Wellington Management Group LLP | 0.00% | Reduce -11.9% | 626,361 | $2.8M |
| Seven Fleet Capital Management LP | 0.88% | Add +274.2% | 625,708 | $2.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.6% | 608,123 | $2.7M |
| Nuveen, LLC | 0.00% | Add +0.7% | 549,153 | $2.5M |
| UBS Group AG | 0.00% | Add +35.1% | 517,698 | $2.3M |
| Woodline Partners LP | 0.01% | Add +2.8% | 513,828 | $2.3M |
| Voya Investment Management LLC | 0.00% | Add +134.7% | 511,983 | $2.3M |
| Dimensional Fund Advisors LP | 0.00% | No change | 490,472 | $2.2M |
| Jefferies Financial Group Inc. | 0.03% | Add +1816.0% | 479,000 | $2.1M |
| Point72 Asset Management | 0.00% | Reduce -88.1% | 461,856 | $2.1M |
| Acuta Capital Partners, LLC | 1.40% | Reduce -3.4% | 439,464 | $2.0M |
| Renaissance Technologies | 0.00% | Add +141.5% | 413,203 | $1.8M |
| Citadel Advisors | 0.00% | Reduce -77.8% | 411,135 | $1.8M |
| Squarepoint Ops LLC | 0.00% | Reduce -13.0% | 410,282 | $1.8M |
| Hennion & Walsh Asset Management, Inc. | 0.06% | Add +26.9% | 391,476 | $1.7M |
| Invesco Ltd. | 0.00% | Reduce -72.4% | 368,021 | $1.6M |
| Moore Capital Management, LP | 0.06% | New | 328,831 | $1.5M |
| Polen Capital Management LLC | 0.01% | Add +104.2% | 319,748 | $1.4M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -13.0% | 299,903 | $1.3M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 275,111 | $1.2M |
| Swiss National Bank | 0.00% | No change | 268,800 | $1.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +58.7% | 265,795 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Add +132.7% | 263,332 | $1.2M |
| Rhumbline Advisers | 0.00% | Add +0.4% | 258,530 | $1.2M |
| Superstring Capital Management LP | 0.82% | Reduce -73.7% | 258,269 | $1.2M |
| Chicago Partners Investment Group LLC | 0.03% | Add +2.5% | 170,751 | $1.1M |
| Alliancebernstein L.P. | 0.00% | Add +5.3% | 189,240 | $1.0M |
| Alps Advisors Inc. | 0.00% | Reduce -0.9% | 222,986 | $997K |
| Victory Capital Management Inc. | 0.00% | Reduce -0.0% | 195,745 | $875K |
| Wells Fargo & Company | 0.00% | Reduce -39.9% | 183,334 | $820K |
| Panagora Asset Management Inc. | 0.00% | Add +1473.9% | 182,164 | $814K |
| Privium Fund Management B.V. | 0.17% | Add +10.3% | 181,900 | $813K |
| Deutsche Bank AG | 0.00% | Add +13.1% | 181,769 | $813K |
| AQR Capital Management | 0.00% | Add +5.0% | 177,309 | $793K |
| Wexford Capital LP | 0.12% | Reduce -11.2% | 160,654 | $718K |
| T. Rowe Price Associates Inc. | 0.00% | Add +30.5% | 158,954 | $711K |
| Palumbo Wealth Management LLC | 0.16% | Reduce -17.6% | 146,709 | $656K |
| Tudor Investment Corporation | 0.00% | New | 143,575 | $642K |
| California State Teachers Retirement System | 0.00% | Reduce -1.2% | 136,933 | $612K |
| Profund Advisors LLC | 0.02% | Add +4.7% | 134,671 | $602K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.7% | 124,730 | $549K |
| BNP Paribas Financial Markets | 0.00% | Reduce -30.3% | 120,200 | $537K |
| MetLife Investment Management, LLC | 0.00% | Add +6.0% | 120,116 | $537K |
| Vanguard Global Advisers, LLC | 0.00% | — | 116,691 | $522K |
| Susquehanna International Group, LLP | 0.00% | Reduce -6.9% | 116,297 | $520K |
| Franklin Resources Inc. | 0.00% | No change | 108,399 | $485K |
| Legal & General Group Plc | 0.00% | Reduce -21.7% | 104,308 | $466K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +48.1% | 99,371 | $444K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 90,474 | $404K |
| Balyasny Asset Management L.P. | 0.00% | Add +97.3% | 83,019 | $371K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +19.7% | 80,779 | $361K |
| Janus Henderson Group PLC | 0.00% | No change | 69,000 | $308K |
| New York State Common Retirement Fund | 0.00% | No change | 67,500 | $302K |
| Red Reef Advisors LLC | 0.31% | No change | 65,950 | $295K |
| Creative Planning | 0.00% | Reduce -5.4% | 59,801 | $267K |
| VARCOV Co. | 0.10% | New | 58,511 | $262K |
| Commonwealth Equity Services, LLC | 0.00% | Add +5.0% | 58,442 | $261K |
| Abacus Wealth Partners, LLC | 0.02% | Add +5.6% | 58,241 | $260K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 57,168 | $256K |
| Citigroup Inc. | 0.00% | Reduce -9.4% | 57,080 | $255K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Reduce -2.4% | 56,577 | $253K |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.