Taysha Gene TherapiesTSHA
13F holders, Q2 2025 (June 30)150holders +23
43new positions
20sold out
6famous investors
$2.31avg. 13F price*
At the end of Q2 2025, 150 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, up 23 from Q1 2025. 43 opened new positions and 20 sold out. The largest holders were RTW Investments, LP ($57.8M), Ra Capital Management, L.P. ($54.4M) and Avoro Capital Advisors LLC ($50.1M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 43 | $73.7M |
| Exits | 20 | $2.7M |
All 13F filers, Q1 2025 → Q2 2025: 95,675,958 shares bought and 4,816,623 shares sold, net +90,859,335 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 150 holders
| RTW Investments, LP | 0.82% | Add +33.2% | 25,021,584 | $57.8M |
| Ra Capital Management, L.P. | 0.92% | Add +116.7% | 23,555,648 | $54.4M |
| Avoro Capital Advisors LLC | 0.88% | Add +8.5% | 21,700,000 | $50.1M |
| Morgan Stanley | 0.00% | Add +0.1% | 16,865,082 | $39.0M |
| FMR LLC | 0.00% | Reduce -0.0% | 15,627,822 | $36.1M |
| BlackRock, Inc. | 0.00% | Reduce -2.1% | 13,303,775 | $30.7M |
| Octagon Capital Advisors LP | 6.39% | Add +17.7% | 12,592,500 | $29.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +3406.3% | 12,587,700 | $29.1M |
| Siren, L.L.C. | 1.32% | Add +69.1% | 11,014,737 | $25.4M |
| Vanguard Group Inc. | 0.00% | Add +24.2% | 10,894,127 | $25.2M |
| Jefferies Financial Group Inc. | 0.41% | Add +4105.3% | 10,313,733 | $23.8M |
| Point72 Asset Management | 0.04% | Add +60.1% | 7,317,614 | $16.9M |
| Deerfield Management Company, L.P. | 0.25% | New | 5,386,000 | $12.4M |
| State Street Corp. | 0.00% | Add +58.9% | 5,138,310 | $11.9M |
| Polar Capital Holdings Plc | 0.06% | Add +66.7% | 5,000,000 | $11.6M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | New | 4,839,000 | $11.2M |
| Toronto Dominion Bank | 0.02% | New | 4,728,806 | $10.9M |
| Tybourne Capital Management (hk) Ltd. | 27.39% | Add +10.7% | 4,095,000 | $9.5M |
| Baker Bros. Advisors LP | 0.09% | No change | 4,004,756 | $9.3M |
| Geode Capital Management, LLC | 0.00% | Add +3.5% | 3,793,572 | $8.8M |
| Montanova Capital, LLC | 0.28% | New | 3,217,449 | $7.4M |
| ADAR1 Capital Management, LLC | 1.14% | Add +182.3% | 3,009,870 | $7.0M |
| Vestal Point Capital, LP | 0.36% | New | 3,000,000 | $6.9M |
| MPM Bioimpact LLC | 1.18% | New | 2,953,562 | $6.8M |
| Millennium Management | 0.01% | Add +65.6% | 2,935,728 | $6.8M |
| B Group, Inc. | 3.59% | Add +43.4% | 1,800,556 | $4.2M |
| Great Point Partners LLC | 2.25% | New | 1,500,000 | $3.5M |
| Northern Trust Corp. | 0.00% | Reduce -7.2% | 1,328,741 | $3.1M |
| Palo Alto Investors LP | 0.61% | Reduce -12.2% | 1,246,033 | $2.9M |
| Stempoint Capital LP | 0.90% | New | 1,203,941 | $2.8M |
| Woodline Partners LP | 0.01% | Add +16.6% | 1,000,254 | $2.3M |
| Granahan Investment Management, LLC | 0.09% | Reduce -41.6% | 958,493 | $2.2M |
| Tang Capital Management LLC | 0.11% | New | 900,000 | $2.1M |
| Quantum Private Wealth, LLC | 0.61% | Add +3.1% | 815,976 | $1.9M |
| Anson Funds Management LP | 0.34% | New | 803,500 | $1.9M |
| Bank of America Corp. | 0.00% | Add +14.7% | 730,728 | $1.7M |
| Sands Capital Alternatives, LLC | 0.33% | No change | 724,873 | $1.7M |
| Alphabet Inc. | 0.07% | No change | 640,882 | $1.5M |
| Wellington Management Group LLP | 0.00% | Add +1.7% | 635,968 | $1.5M |
| Citadel Advisors | 0.00% | Add +144.2% | 528,993 | $1.2M |
| Royal Bank of Canada | 0.00% | Add +33779.0% | 495,311 | $1.1M |
| SG Americas Securities, LLC | 0.01% | New | 493,301 | $1.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -10.1% | 491,709 | $1.1M |
| Acuta Capital Partners, LLC | 1.57% | New | 485,669 | $1.1M |
| Nuveen, LLC | 0.00% | Reduce -14.9% | 465,144 | $1.1M |
| Bank of New York Mellon Corp | 0.00% | Add +1.2% | 458,659 | $1.1M |
| Barclays PLC | 0.00% | Reduce -36.5% | 450,501 | $1.0M |
| Sphera Funds Management LTD. | 0.25% | New | 420,000 | $970K |
| D. E. Shaw & Co. | 0.00% | New | 401,509 | $927K |
| XTX Topco Ltd | 0.03% | Add +57.9% | 320,737 | $741K |
| NorthCoast Asset Management LLC | 0.00% | Add +2.0% | 298,667 | $690K |
| UBS Group AG | 0.00% | Reduce -37.5% | 261,239 | $603K |
| Rhumbline Advisers | 0.00% | Add +13.5% | 233,256 | $539K |
| JPMorgan Chase & Co. | 0.00% | Reduce -77.8% | 222,649 | $514K |
| Susquehanna International Group, LLP | 0.00% | Reduce -6.5% | 212,572 | $491K |
| Invesco Ltd. | 0.00% | Add +27.4% | 203,671 | $470K |
| Affinity Asset Advisors, LLC | 0.07% | New | 200,000 | $462K |
| Chicago Partners Investment Group LLC | 0.01% | Add +40.5% | 163,766 | $441K |
| Alliancebernstein L.P. | 0.00% | Add +65.9% | 179,620 | $415K |
| Quadrature Capital Ltd | 0.01% | New | 161,940 | $373K |
| ExodusPoint Capital Management, LP | 0.00% | New | 148,357 | $343K |
| Jane Street Group, LLC | 0.00% | New | 136,994 | $316K |
| Privium Fund Management B.V. | 0.07% | No change | 134,900 | $316K |
| AQR Capital Management | 0.00% | Add +25.8% | 135,766 | $314K |
| Citigroup Inc. | 0.00% | Reduce -2.2% | 130,317 | $301K |
| Rafferty Asset Management, LLC | 0.00% | New | 118,683 | $274K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -17.6% | 117,740 | $272K |
| Franklin Resources Inc. | 0.00% | Reduce -6.7% | 108,399 | $250K |
| MetLife Investment Management, LLC | 0.00% | Add +0.3% | 108,078 | $250K |
| Deutsche Bank AG | 0.00% | Reduce -19.9% | 107,716 | $249K |
| Wells Fargo & Company | 0.00% | Reduce -1.7% | 107,234 | $248K |
| Squarepoint Ops LLC | 0.00% | New | 100,226 | $232K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -6.3% | 96,543 | $223K |
| T. Rowe Price Associates Inc. | 0.00% | Add +14.3% | 84,603 | $196K |
| Intech Investment Management LLC | 0.00% | Reduce -17.7% | 82,195 | $190K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | New | 80,571 | $186K |
| Marshall Wace, LLP | 0.00% | New | 79,498 | $184K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 72,900 | $168K |
| EntryPoint Capital, LLC | 0.08% | Reduce -49.1% | 69,109 | $160K |
| Militia Capital Partners, LP | 0.07% | New | 66,800 | $154K |
| Engineers Gate Manager LP | 0.00% | New | 64,617 | $149K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.4% | 61,005 | $141K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -0.1% | 60,036 | $139K |
| Axq Capital, LP | 0.04% | New | 57,000 | $132K |
| Renaissance Technologies | 0.00% | New | 54,900 | $127K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +27.7% | 52,527 | $121K |
| Creative Planning | 0.00% | Reduce -33.6% | 51,981 | $120K |
| Voya Investment Management LLC | 0.00% | Reduce -3.0% | 47,169 | $109K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 45,678 | $106K |
| Williams & Novak, LLC | 0.09% | No change | 45,000 | $104K |
| Gsa Capital Partners LLP | 0.01% | New | 44,690 | $103K |
| ProShare Advisors LLC | 0.00% | Reduce -7.3% | 43,746 | $101K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -51.4% | 35,484 | $82K |
| Two Sigma Investments, LP | 0.00% | New | 32,682 | $75K |
| Ethic Inc. | 0.00% | New | 27,975 | $67K |
| First Manhattan Co. Llc. | 0.00% | No change | 28,500 | $66K |
| Leonteq Securities AG | 0.00% | Reduce -65.0% | 27,999 | $65K |
| Profund Advisors LLC | 0.00% | New | 26,599 | $61K |
| Victory Capital Management Inc. | 0.00% | Add +34.0% | 25,492 | $59K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | New | 25,252 | $58K |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.