Tyra BiosciencesTYRA
13F holders, Q1 2025 (March 31)117holders +4
20new positions
16sold out
5famous investors
$9.32avg. 13F price*
At the end of Q1 2025, 117 institutions reported holding Tyra Biosciences Inc. (TYRA) in their 13F filings, up 4 from Q4 2024. 20 opened new positions and 16 sold out. The largest holders were Ra Capital Management, L.P. ($98.9M), Canaan Partners XI LLC ($38.5M) and Alta Partners Management Company, L.P. ($37.9M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Tyra Biosciences Inc.
- CUSIP
- 90240B106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $15.5M |
| Exits | 16 | $34.1M |
All 13F filers, Q4 2024 → Q1 2025: 9,034,055 shares bought and 4,074,194 shares sold, net +4,959,861 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 117 holders
| Ra Capital Management, L.P. | 1.65% | No change | 10,637,290 | $98.9M |
| Canaan Partners XI LLC | 58.09% | Reduce -0.8% | 4,144,590 | $38.5M |
| Alta Partners Management Company, L.P. | 90.83% | No change | 4,080,296 | $37.9M |
| Nextech Invest Ltd. | 8.77% | — | 4,055,861 | $37.7M |
| BVF Inc. | 1.50% | No change | 3,944,194 | $36.7M |
| TCG Crossover Management, LLC | 3.68% | Add +45.7% | 2,898,103 | $27.0M |
| Vestal Point Capital, LP | 1.91% | Add +190.9% | 2,879,829 | $26.8M |
| Janus Henderson Group PLC | 0.01% | Add +54.2% | 2,693,237 | $26.3M |
| Kynam Capital Management, LP | 1.91% | Add +353.6% | 2,406,067 | $22.4M |
| Orbimed Advisors LLC | 0.39% | Add +19.2% | 1,752,831 | $16.3M |
| FMR LLC | 0.00% | Reduce -45.1% | 1,707,148 | $15.9M |
| BlackRock, Inc. | 0.00% | Reduce -1.3% | 1,695,917 | $15.8M |
| Vanguard Group Inc. | 0.00% | Add +0.9% | 1,218,371 | $11.3M |
| Farallon Capital Management, L.L.C. | 0.06% | Add +14.3% | 1,143,818 | $10.6M |
| Commodore Capital LP | 0.65% | New | 950,000 | $8.8M |
| 5AM Venture Management, LLC | 3.30% | No change | 939,298 | $8.7M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.3% | 516,290 | $4.8M |
| Pictet Asset Management Holding SA | 0.00% | Add +29.7% | 459,113 | $4.3M |
| Sio Capital Management, LLC | 1.17% | Add +73.0% | 416,617 | $3.9M |
| State Street Corp. | 0.00% | Add +1.6% | 413,988 | $3.9M |
| Millennium Management | 0.00% | Add +28.3% | 404,165 | $3.8M |
| Marshall Wace, LLP | 0.00% | Add +604.0% | 380,700 | $3.5M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +23.6% | 301,801 | $2.8M |
| Balyasny Asset Management L.P. | 0.01% | New | 243,244 | $2.3M |
| Northern Trust Corp. | 0.00% | Reduce -2.8% | 216,447 | $2.0M |
| Morgan Stanley | 0.00% | Add +143.6% | 180,590 | $1.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.8% | 164,108 | $1.5M |
| Polar Asset Management Partners Inc. | 0.06% | Add +27.1% | 141,241 | $1.3M |
| Walleye Capital LLC | 0.02% | Add +123.5% | 140,742 | $1.3M |
| AXA S.A. | 0.00% | New | 128,189 | $1.2M |
| Ally Bridge Group (NY) LLC | 0.90% | Reduce -38.7% | 107,244 | $997K |
| Wellington Management Group LLP | 0.00% | Add +9.7% | 104,087 | $968K |
| Woodline Partners LP | 0.01% | New | 100,108 | $931K |
| Citadel Advisors | 0.00% | Add +73.2% | 96,282 | $895K |
| Cubist Systematic Strategies, LLC | 0.01% | Reduce -16.3% | 91,844 | $854K |
| JPMorgan Chase & Co. | 0.00% | Reduce -6.2% | 85,490 | $795K |
| Investment Counsel Co. of Nevada | 1.80% | No change | 85,020 | $791K |
| Bank of America Corp. | 0.00% | Add +26.3% | 83,521 | $777K |
| Goldman Sachs Group Inc. | 0.00% | Add +21.7% | 78,006 | $725K |
| Oppenheimer & Co. Inc. | 0.01% | Reduce -0.8% | 74,805 | $696K |
| BNP Paribas Financial Markets | 0.00% | Add +1496.8% | 68,950 | $641K |
| Two Sigma Investments, LP | 0.00% | Add +40.1% | 64,818 | $603K |
| State of Wisconsin Investment Board | 0.00% | Reduce -9.7% | 58,712 | $546K |
| Victory Capital Management Inc. | 0.00% | Reduce -0.9% | 56,150 | $522K |
| Raymond James Financial Inc. | 0.00% | Reduce -0.8% | 54,344 | $505K |
| Renaissance Technologies | 0.00% | Add +76.6% | 51,400 | $478K |
| Two Sigma Advisers, LP | 0.00% | Add +307.3% | 50,100 | $466K |
| Nuveen, LLC | 0.00% | — | 49,998 | $465K |
| Point72 Asset Management | 0.00% | Add +288.0% | 49,600 | $461K |
| Brevan Howard Capital Management LP | 0.01% | New | 46,371 | $431K |
| UBS Group AG | 0.00% | Reduce -3.3% | 46,286 | $430K |
| Barclays PLC | 0.00% | Reduce -1.3% | 42,511 | $395K |
| Verition Fund Management LLC | 0.00% | New | 42,174 | $392K |
| Bank of New York Mellon Corp | 0.00% | Reduce -8.7% | 41,083 | $382K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | No change | 35,635 | $331K |
| Ikarian Capital, LLC | 0.11% | Reduce -41.7% | 35,000 | $326K |
| Jane Street Group, LLC | 0.00% | New | 34,813 | $324K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -8.6% | 34,712 | $323K |
| ExodusPoint Capital Management, LP | 0.00% | New | 30,235 | $281K |
| AlphaQuest LLC | 0.03% | Add +489.7% | 29,622 | $275K |
| Swiss National Bank | 0.00% | Add +42.0% | 29,400 | $273K |
| Rhumbline Advisers | 0.00% | Add +7.2% | 28,081 | $261K |
| Jump Financial, LLC | 0.00% | Add +84.4% | 27,949 | $260K |
| Caligan Partners LP | 0.05% | New | 25,000 | $233K |
| HighVista Strategies LLC | 0.09% | No change | 23,941 | $223K |
| Susquehanna International Group, LLP | 0.00% | New | 23,526 | $219K |
| American Century Companies Inc. | 0.00% | Add +5.8% | 23,431 | $218K |
| Auour Investments LLC | 0.08% | No change | 21,020 | $217K |
| Alliancebernstein L.P. | 0.00% | No change | 17,570 | $163K |
| Deutsche Bank AG | 0.00% | Reduce -10.2% | 16,979 | $158K |
| Citigroup Inc. | 0.00% | Reduce -7.7% | 15,507 | $144K |
| SG Americas Securities, LLC | 0.00% | Add +56.3% | 15,120 | $141K |
| EntryPoint Capital, LLC | 0.06% | Reduce -18.2% | 14,892 | $138K |
| Intech Investment Management LLC | 0.00% | New | 13,597 | $126K |
| MetLife Investment Management, LLC | 0.00% | No change | 12,207 | $114K |
| Tudor Investment Corporation | 0.00% | Reduce -22.4% | 12,093 | $112K |
| Exchange Traded Concepts, LLC | 0.00% | Add +42.7% | 11,861 | $110K |
| Aquatic Capital Management LLC | 0.00% | Add +156.9% | 11,781 | $110K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -1.1% | 11,514 | $107K |
| Virtus Investment Advisers, LLC | 0.03% | New | 10,818 | $101K |
| Baker Bros. Advisors LP | 0.00% | No change | 10,607 | $99K |
| California State Teachers Retirement System | 0.00% | No change | 10,570 | $98K |
| Axq Capital, LP | 0.04% | New | 10,302 | $96K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -2.1% | 10,239 | $95K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.4% | 10,150 | $94K |
| Corebridge Financial, Inc. | 0.00% | Reduce -5.1% | 9,590 | $89K |
| Wells Fargo & Company | 0.00% | Reduce -1.5% | 9,353 | $87K |
| Legal & General Group Plc | 0.00% | Reduce -0.8% | 9,261 | $86K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | New | 9,047 | $84K |
| New York State Common Retirement Fund | 0.00% | No change | 7,423 | $69K |
| US Bancorp \de | 0.00% | Add +50.5% | 5,435 | $51K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 5,049 | $47K |
| Point72 (DIFC) Ltd | 0.00% | Add +305.2% | 2,273 | $21K |
| KLP Kapitalforvaltning As | 0.00% | No change | 2,200 | $20K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +47.0% | 2,083 | $19K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,991 | $19K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 1,693 | $17K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,296 | $12K |
| Osaic Holdings, Inc. | 0.00% | Add +3695.4% | 835 | $8K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | New | 792 | $7K |
"% of holder's portfolio" is TYRA's weight in each manager's 13F, not the share of Tyra Biosciences Inc. the manager owns.