Tyra BiosciencesTYRA
13F holders, Q2 2025 (June 30)121holders +4
18new positions
15sold out
6famous investors
$9.57avg. 13F price*
At the end of Q2 2025, 121 institutions reported holding Tyra Biosciences Inc. (TYRA) in their 13F filings, up 4 from Q1 2025. 18 opened new positions and 15 sold out. The largest holders were Ra Capital Management, L.P. ($116.7M), Alta Partners Management Company, L.P. ($39.0M) and Nextech Invest Ltd. ($38.8M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Tyra Biosciences Inc.
- CUSIP
- 90240B106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 18 | $4.1M |
| Exits | 15 | $8.1M |
All 13F filers, Q1 2025 → Q2 2025: 7,430,079 shares bought and 4,414,909 shares sold, net +3,015,170 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 121 holders
| Ra Capital Management, L.P. | 1.97% | Add +14.7% | 12,198,625 | $116.7M |
| Alta Partners Management Company, L.P. | 93.82% | No change | 4,080,296 | $39.0M |
| Nextech Invest Ltd. | 7.35% | No change | 4,055,861 | $38.8M |
| BVF Inc. | 1.35% | No change | 3,944,194 | $37.7M |
| Canaan Partners XI LLC | 20.10% | Reduce -12.9% | 3,608,109 | $34.5M |
| Commodore Capital LP | 2.09% | Add +226.3% | 3,100,000 | $29.7M |
| TCG Crossover Management, LLC | 3.17% | No change | 2,898,103 | $27.7M |
| Janus Henderson Group PLC | 0.01% | Add +6.0% | 2,856,290 | $27.3M |
| Vestal Point Capital, LP | 1.34% | Reduce -7.8% | 2,655,000 | $25.4M |
| Kynam Capital Management, LP | 2.40% | Reduce -3.2% | 2,329,998 | $22.3M |
| BlackRock, Inc. | 0.00% | Add +11.6% | 1,893,328 | $18.1M |
| Vanguard Group Inc. | 0.00% | Add +15.1% | 1,401,693 | $13.4M |
| Farallon Capital Management, L.L.C. | 0.05% | No change | 1,143,818 | $10.9M |
| 5AM Venture Management, LLC | 3.46% | No change | 939,298 | $9.0M |
| Sio Capital Management, LLC | 3.11% | Add +94.5% | 810,274 | $7.8M |
| Orbimed Advisors LLC | 0.19% | Reduce -54.1% | 804,603 | $7.7M |
| Balyasny Asset Management L.P. | 0.01% | Add +139.8% | 583,386 | $5.6M |
| Geode Capital Management, LLC | 0.00% | Add +9.8% | 567,126 | $5.4M |
| Marshall Wace, LLP | 0.00% | Add +12.4% | 428,108 | $4.1M |
| State Street Corp. | 0.00% | Add +1.2% | 418,984 | $4.0M |
| Millennium Management | 0.00% | Add +0.8% | 407,464 | $3.9M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +31.0% | 395,299 | $3.8M |
| Morgan Stanley | 0.00% | Add +109.5% | 378,402 | $3.6M |
| Bank of America Corp. | 0.00% | Add +346.6% | 372,967 | $3.6M |
| Walleye Capital LLC | 0.04% | Add +163.2% | 370,408 | $3.5M |
| Point72 Asset Management | 0.01% | Add +353.0% | 224,700 | $2.2M |
| Citadel Advisors | 0.00% | Add +124.5% | 216,136 | $2.1M |
| Northern Trust Corp. | 0.00% | Reduce -5.2% | 205,308 | $2.0M |
| Caligan Partners LP | 0.35% | Add +659.8% | 189,950 | $1.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +8.5% | 178,104 | $1.7M |
| Renaissance Technologies | 0.00% | Add +162.8% | 135,100 | $1.3M |
| AXA S.A. | 0.00% | Add +0.2% | 128,400 | $1.2M |
| Cubist Systematic Strategies, LLC | 0.01% | Add +32.9% | 122,036 | $1.2M |
| Two Sigma Investments, LP | 0.00% | Add +63.3% | 105,825 | $1.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +35.4% | 105,595 | $1.0M |
| Wellington Management Group LLP | 0.00% | Reduce -1.0% | 103,078 | $986K |
| JPMorgan Chase & Co. | 0.00% | Add +20.4% | 102,917 | $985K |
| Woodline Partners LP | 0.01% | No change | 100,108 | $958K |
| BNP Paribas Financial Markets | 0.00% | Add +41.8% | 97,736 | $935K |
| Two Sigma Advisers, LP | 0.00% | Add +73.7% | 87,000 | $833K |
| Investment Counsel Co. of Nevada | 1.67% | No change | 85,020 | $814K |
| Ameriprise Financial Inc. | 0.00% | New | 80,602 | $771K |
| Nuveen, LLC | 0.00% | Add +60.9% | 80,441 | $770K |
| State of Wisconsin Investment Board | 0.00% | Add +30.2% | 76,449 | $732K |
| Oppenheimer & Co. Inc. | 0.01% | Reduce -1.0% | 74,033 | $708K |
| AlphaQuest LLC | 0.07% | Add +146.7% | 73,073 | $699K |
| Jump Financial, LLC | 0.01% | Add +154.5% | 71,119 | $681K |
| ExodusPoint Capital Management, LP | 0.01% | Add +123.1% | 67,442 | $645K |
| Raymond James Financial Inc. | 0.00% | Add +16.3% | 63,187 | $605K |
| Barclays PLC | 0.00% | Add +44.8% | 61,555 | $589K |
| Jane Street Group, LLC | 0.00% | Add +67.1% | 58,168 | $557K |
| Bank of New York Mellon Corp | 0.00% | Add +31.5% | 54,039 | $517K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | New | 48,644 | $466K |
| UBS Group AG | 0.00% | Reduce -0.0% | 46,268 | $443K |
| Trexquant Investment LP | 0.00% | New | 44,681 | $428K |
| Victory Capital Management Inc. | 0.00% | Reduce -21.3% | 44,190 | $423K |
| PDT Partners, LLC | 0.02% | New | 43,310 | $414K |
| Dimensional Fund Advisors LP | 0.00% | Add +20.1% | 41,681 | $399K |
| Verition Fund Management LLC | 0.00% | Reduce -2.9% | 40,939 | $392K |
| Rhumbline Advisers | 0.00% | Add +44.9% | 40,685 | $389K |
| Susquehanna International Group, LLP | 0.00% | Add +60.6% | 37,782 | $362K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -21.1% | 36,594 | $350K |
| Alliancebernstein L.P. | 0.00% | Add +102.8% | 35,640 | $341K |
| XTX Topco Ltd | 0.01% | New | 34,601 | $331K |
| Dynamic Technology Lab Private Ltd | 0.04% | New | 34,115 | $326K |
| Squarepoint Ops LLC | 0.00% | New | 31,408 | $301K |
| American Century Companies Inc. | 0.00% | Add +23.1% | 28,854 | $276K |
| Alps Advisors Inc. | 0.00% | New | 28,729 | $275K |
| AQR Capital Management | 0.00% | New | 28,712 | $275K |
| Tudor Investment Corporation | 0.00% | Add +117.2% | 26,265 | $251K |
| HighVista Strategies LLC | 0.09% | Add +4.3% | 24,962 | $239K |
| Corton Capital Inc. | 0.27% | New | 24,346 | $233K |
| Auour Investments LLC | 0.07% | No change | 21,020 | $201K |
| Intech Investment Management LLC | 0.00% | Add +46.5% | 19,919 | $191K |
| Public Employees Retirement System of Ohio | 0.00% | New | 18,512 | $177K |
| Royal Bank of Canada | 0.00% | Add +2294.8% | 16,213 | $156K |
| Wells Fargo & Company | 0.00% | Add +65.3% | 15,457 | $148K |
| MetLife Investment Management, LLC | 0.00% | Add +19.9% | 14,631 | $140K |
| Aquatic Capital Management LLC | 0.00% | Add +16.7% | 13,744 | $132K |
| Deutsche Bank AG | 0.00% | Reduce -21.7% | 13,300 | $127K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +14.5% | 13,182 | $126K |
| Axq Capital, LP | 0.04% | Add +19.9% | 12,350 | $118K |
| FMR LLC | 0.00% | Reduce -99.3% | 12,202 | $117K |
| T. Rowe Price Associates Inc. | 0.00% | New | 12,022 | $116K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +5.2% | 10,681 | $102K |
| Baker Bros. Advisors LP | 0.00% | No change | 10,607 | $102K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -2.6% | 9,975 | $95K |
| Citigroup Inc. | 0.00% | Reduce -38.8% | 9,497 | $91K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -15.8% | 9,103 | $87K |
| US Bancorp \de | 0.00% | Add +39.1% | 7,561 | $72K |
| New York State Common Retirement Fund | 0.00% | No change | 7,423 | $71K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 5,049 | $48K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | Add +340.7% | 3,490 | $33K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +36.3% | 2,840 | $27K |
| Point72 (DIFC) Ltd | 0.00% | Add +2.5% | 2,330 | $22K |
| Legal & General Group Plc | 0.00% | Reduce -76.3% | 2,192 | $21K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +21.3% | 2,054 | $20K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,991 | $19K |
| Cwm, LLC | 0.00% | Add +302.4% | 1,541 | $15K |
| California State Teachers Retirement System | 0.00% | Reduce -86.1% | 1,472 | $14K |
"% of holder's portfolio" is TYRA's weight in each manager's 13F, not the share of Tyra Biosciences Inc. the manager owns.