SS SPDR S&P Biotech ETFXBIETF
13F holders, Q4 2025 (December 31)816holders +160
188new positions
51sold out
4famous investors
$122.30avg. 13F price*
At the end of Q4 2025, 816 institutions reported holding SS SPDR S&P Biotech ETF (XBI) in their 13F filings, up 160 from Q3 2025. 188 opened new positions and 51 sold out. The largest holders were Goldman Sachs Group Inc. ($2.4B), BNP Paribas Financial Markets ($2.0B) and Bank of America Corp. ($1.6B). 4 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- SS SPDR S&P Biotech ETF
- Filed as
- SPDR SERIES TRUST (Q4 2025)
- CUSIP
- 78464A870
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 188 | $746.8M |
| Exits | 51 | $128.2M |
All 13F filers, Q3 2025 → Q4 2025: 31,307,689 shares bought and 20,998,463 shares sold, net +10,309,226 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 816 holders
| Goldman Sachs Group Inc. | 0.35% | Reduce -12.5% | 19,896,418 | $2.4B |
| BNP Paribas Financial Markets | 1.30% | Add +178.1% | 16,587,354 | $2.0B |
| Bank of America Corp. | 0.11% | Add +36.3% | 12,817,176 | $1.6B |
| Healthcare of Ontario Pension Plan Trust Fund | 2.62% | Reduce -8.9% | 12,592,500 | $1.5B |
| Citigroup Inc. | 1.05% | Add +15.0% | 12,527,210 | $1.5B |
| Morgan Stanley | 0.08% | Add +8.3% | 11,491,683 | $1.4B |
| Wells Fargo & Company | 0.09% | Add +28.3% | 3,566,265 | $434.8M |
| JPMorgan Chase & Co. | 0.03% | Reduce -75.9% | 3,265,689 | $398.2M |
| UBS Group AG | 0.07% | Add +23.7% | 2,977,121 | $363.0M |
| Avoro Capital Advisors LLC | 2.52% | New | 2,100,000 | $256.1M |
| Barclays PLC | 0.09% | Reduce -5.7% | 1,890,408 | $230.5M |
| Bessemer Group Inc. | 0.35% | Add +13.5% | 1,853,232 | $226.0M |
| Two Sigma Investments, LP | 0.34% | Add +21136.1% | 1,762,600 | $214.9M |
| Canada Pension Plan Investment Board | 0.14% | No change | 1,758,000 | $214.4M |
| Jefferies Financial Group Inc. | 1.76% | Add +13.9% | 1,715,089 | $209.1M |
| OMERS ADMINISTRATION Corp | 1.03% | Add +42425.3% | 1,190,707 | $145.1M |
| Meitav Investment House Ltd. | 1.36% | Add +42.1% | 969,419 | $118.2M |
| LPL Financial LLC | 0.03% | Add +28.4% | 875,547 | $106.8M |
| D. E. Shaw & Co. | 0.07% | New | 737,777 | $90.0M |
| Employees Retirement System of Texas | 0.84% | Reduce -1.8% | 725,272 | $88.4M |
| Clal Insurance Enterprises Holdings Ltd | 0.54% | Add +61.5% | 691,000 | $84.3M |
| Greenhouse Funds LLLP | 3.24% | Add +1.7% | 687,524 | $83.8M |
| Ameriprise Financial Inc. | 0.02% | Reduce -44.6% | 678,726 | $82.7M |
| HSBC Holdings PLC | 0.04% | Add +7.8% | 638,529 | $78.0M |
| Assetmark, Inc. | 0.16% | Add +1042265.6% | 635,843 | $77.5M |
| Sumitomo Mitsui Financial Group, Inc. | 1.14% | Reduce -17.4% | 9,424 | $64.4M |
| Natixis | 0.24% | Reduce -1.0% | 493,049 | $60.1M |
| Royal Bank of Canada | 0.01% | Add +11.1% | 491,613 | $59.9M |
| Raymond James Financial Inc. | 0.02% | Add +22.1% | 466,018 | $56.8M |
| Investure, LLC | 2.81% | No change | 412,250 | $50.3M |
| Clearbridge Investments, LLC | 0.04% | Add +9.8% | 395,991 | $48.3M |
| STRS Ohio | 0.18% | Reduce -3.4% | 391,200 | $47.7M |
| Susquehanna International Group, LLP | 0.06% | Reduce -68.1% | 367,910 | $44.9M |
| Main Street Research LLC | 2.51% | New | 360,526 | $44.0M |
| DAFNA Capital Management LLC | 9.65% | Reduce -16.2% | 336,505 | $41.0M |
| SG Americas Securities, LLC | 0.05% | Add +142.8% | 305,105 | $37.2M |
| Stifel Financial Corp. | 0.03% | Reduce -5.9% | 304,503 | $37.1M |
| LMR Partners LLP | 0.46% | New | 298,647 | $36.4M |
| Strategic Financial Services, Inc. | 1.51% | Reduce -8.5% | 260,924 | $32.7M |
| Gendell Jeffrey L | 0.56% | Add +12.9% | 262,278 | $32.0M |
| Jain Global LLC | 0.31% | Add +165.9% | 249,894 | $30.5M |
| Neuberger Berman Group LLC | 0.02% | Reduce -1.8% | 243,257 | $29.7M |
| Whittier Trust Co. | 0.31% | Add +2.3% | 237,935 | $29.0M |
| Marks Wealth, LLC | 9.66% | New | 236,668 | $28.9M |
| Rockefeller Capital Management L.P. | 0.05% | Add +44.5% | 236,057 | $28.8M |
| BlackRock, Inc. | 0.00% | Reduce -9.0% | 232,792 | $28.4M |
| Moore Capital Management, LP | 0.58% | Reduce -10.0% | 225,000 | $27.4M |
| Sivik Global Healthcare LLC | 13.39% | Reduce -10.0% | 225,000 | $27.4M |
| Rock Springs Capital Management LP | 1.39% | Add +46.3% | 222,000 | $27.1M |
| FIL Ltd | 0.02% | Add +2158.5% | 207,577 | $25.4M |
| State of Wisconsin Investment Board | 0.06% | New | 206,304 | $25.2M |
| United Capital Management of KS, Inc. | 3.18% | Reduce -1.3% | 186,145 | $22.7M |
| Osborne Partners Capital Management, LLC | 1.14% | Reduce -3.5% | 180,964 | $22.1M |
| Allspring Global Investments Holdings, LLC | 0.03% | Reduce -26.9% | 177,012 | $21.5M |
| GenTrust, LLC | 0.93% | Add +0.1% | 175,663 | $21.4M |
| Commonwealth Equity Services, LLC | 0.03% | Add +34.7% | 166,136 | $20.3M |
| Cetera Investment Advisers | 0.02% | Add +6.2% | 163,181 | $19.9M |
| Bank of Montreal | 0.01% | Add +42.1% | 162,623 | $19.8M |
| Weatherly Asset Management L. P. | 1.48% | Add +1.6% | 158,225 | $19.3M |
| Royal Fund Management, LLC | 1.61% | New | 143,713 | $17.5M |
| Williams Jones Wealth Management, LLC. | 0.20% | Add +1196.7% | 143,236 | $17.5M |
| Altfest L J & Co. Inc. | 1.90% | Add +13.8% | 142,171 | $17.3M |
| Thrivent Financial for Lutherans | 0.03% | Add +66.3% | 137,863 | $16.8M |
| L. Roy Papp & Associates, LLP | 1.84% | Reduce -1.7% | 136,229 | $16.6M |
| WS Management LLLP | 2.12% | Add +70.0% | 130,000 | $15.9M |
| Osaic Holdings, Inc. | 0.02% | Add +23.7% | 128,040 | $15.6M |
| Madrona Financial Services, LLC | 3.31% | Reduce -1.2% | 126,951 | $15.5M |
| Whittier Trust Co. of Nevada Inc. | 0.31% | Reduce -0.6% | 122,085 | $14.9M |
| Cambridge Investment Research Advisors, Inc. | 0.04% | Add +139.3% | 117,168 | $14.3M |
| Northwestern Mutual Wealth Management Co. | 0.01% | Reduce -3.4% | 116,119 | $14.2M |
| Zweig-DiMenna Associates LLC | 0.96% | New | 110,700 | $13.5M |
| Edge Wealth Management LLC | 2.37% | Reduce -2.0% | 110,031 | $13.4M |
| Riggs Asset Managment Co. Inc. | 2.62% | New | 106,548 | $13.0M |
| JBF Capital, Inc. | 1.85% | Add +600.0% | 105,000 | $12.8M |
| Yelin Lapidot Holdings Management Ltd. | 2.55% | No change | 104,532 | $12.7M |
| Blair William & Co. | 0.03% | Add +1.0% | 102,867 | $12.5M |
| S&co Inc. | 0.77% | Reduce -2.7% | 102,227 | $12.5M |
| Lalia Capital, LLC | 9.55% | — | 100,000 | $12.2M |
| Mirae Asset Securities (usa) Inc. | 0.48% | Reduce -93.3% | 100,000 | $12.2M |
| Walleye Trading LLC | 0.19% | Add +217.9% | 99,320 | $12.1M |
| Keystone Investors Pte Ltd. | 1.08% | New | 98,600 | $12.0M |
| Wealth Enhancement Advisory Services, LLC | 0.02% | Reduce -2.2% | 97,886 | $12.0M |
| Focus Partners Wealth | 0.01% | Add +212.3% | 94,563 | $11.4M |
| GTS Securities LLC | 0.39% | Add +678.3% | 93,078 | $11.3M |
| Investment House LLC | 0.53% | Reduce -0.5% | 91,495 | $11.2M |
| Ilmarinen Mutual Pension Insurance Co | 0.09% | No change | 90,329 | $11.0M |
| Janney Montgomery Scott LLC | 0.03% | Add +108.6% | 89,731 | $10.9M |
| JTC Employer Solutions Trustee Ltd | 0.70% | Add +5367.4% | 84,745 | $10.3M |
| Tocqueville Asset Management L.P. | 0.15% | Reduce -0.1% | 84,715 | $10.3M |
| Parkside Investments, LLC | 1.29% | Reduce -9.6% | 84,247 | $10.3M |
| Lhm, Inc. | 3.80% | Reduce -29.9% | 83,738 | $10.2M |
| Verition Fund Management LLC | 0.06% | No change | 83,176 | $10.1M |
| Strategic Wealth Partners, Ltd. | 0.69% | Add +13.9% | 83,163 | $10.1M |
| Rokos Capital Management LLP | 0.15% | New | 81,960 | $10.0M |
| Castleark Management LLC | 0.29% | No change | 80,890 | $9.9M |
| Envestnet Asset Management Inc. | 0.00% | Add +42.6% | 80,752 | $9.8M |
| Qube Research & Technologies Ltd | 0.01% | New | 77,500 | $9.4M |
| Virtus Wealth Solutions LLC | 1.74% | New | 75,205 | $9.2M |
| Spire Wealth Management | 0.31% | Add +507.2% | 75,082 | $9.2M |
| Geneva Partners, LLC | 3.23% | New | 74,465 | $9.1M |
"% of holder's portfolio" is XBI's weight in each manager's 13F, not the share of SS SPDR S&P Biotech ETF the manager owns.