Xeris Biopharma HoldingsXERS
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 200 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 1 from Q1 2025. 23 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($53.9M), Vanguard Group Inc. ($45.8M) and D. E. Shaw & Co. ($17.9M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Xeris Biopharma Holdings Inc.
- CUSIP
- 98422E103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $3.2M |
| Exits | 24 | $14.5M |
All 13F filers, Q1 2025 → Q2 2025: 13,969,335 shares bought and 11,099,696 shares sold, net +2,869,639 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 200 holders
| BlackRock, Inc. | 0.00% | Add +6.9% | 11,536,321 | $53.9M |
| Vanguard Group Inc. | 0.00% | Add +21.1% | 9,816,937 | $45.8M |
| D. E. Shaw & Co. | 0.02% | Add +25.6% | 3,835,407 | $17.9M |
| State Street Corp. | 0.00% | Add +13.8% | 3,783,200 | $17.7M |
| Geode Capital Management, LLC | 0.00% | Add +7.2% | 3,650,688 | $17.1M |
| Morgan Stanley | 0.00% | Reduce -15.1% | 3,642,584 | $17.0M |
| Qube Research & Technologies Ltd | 0.02% | Add +67.5% | 3,089,771 | $14.4M |
| Millennium Management | 0.01% | Add +26.6% | 2,933,620 | $13.7M |
| Nuveen, LLC | 0.00% | Add +16.6% | 2,600,442 | $12.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -18.6% | 2,271,486 | $10.6M |
| Rosalind Advisors, Inc. | 4.87% | Reduce -13.6% | 2,155,594 | $10.1M |
| Parkman Healthcare Partners LLC | 1.14% | Add +18.4% | 2,107,483 | $9.8M |
| Driehaus Capital Management LLC | 0.08% | Add +46.7% | 2,071,075 | $9.7M |
| Renaissance Technologies | 0.01% | Reduce -5.0% | 2,055,340 | $9.6M |
| Legal & General Group Plc | 0.00% | Add +27.8% | 1,804,203 | $8.4M |
| Bank of America Corp. | 0.00% | Reduce -2.7% | 1,663,490 | $7.8M |
| CenterBook Partners LP | 0.41% | Add +237.7% | 1,594,229 | $7.4M |
| Prudential Financial Inc. | 0.01% | Add +41.7% | 1,556,629 | $7.3M |
| Northern Trust Corp. | 0.00% | Add +7.7% | 1,293,530 | $6.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +108.3% | 1,227,959 | $5.7M |
| Two Sigma Investments, LP | 0.01% | Add +36.4% | 1,214,699 | $5.7M |
| Knott David M Jr | 2.24% | Reduce -4.5% | 1,060,000 | $5.0M |
| Two Sigma Advisers, LP | 0.01% | Add +14.2% | 1,056,779 | $4.9M |
| AQR Capital Management | 0.00% | Add +10.8% | 1,048,993 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -51.2% | 1,032,262 | $4.8M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -26.4% | 994,381 | $4.6M |
| Cubist Systematic Strategies, LLC | 0.04% | Add +8.5% | 880,314 | $4.1M |
| Kennedy Capital Management LLC | 0.09% | Add +11.0% | 816,147 | $3.8M |
| Jump Financial, LLC | 0.04% | Add +78.6% | 756,403 | $3.5M |
| Deutsche Bank AG | 0.00% | Reduce -2.6% | 736,927 | $3.4M |
| Essex Investment Management Co. LLC | 0.62% | Reduce -0.6% | 725,774 | $3.4M |
| Federated Hermes, Inc. | 0.01% | Add +0.5% | 691,381 | $3.2M |
| Informed Momentum Co LLC | 0.42% | Reduce -37.2% | 586,865 | $2.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +33.9% | 567,538 | $2.7M |
| Norges Bank | 0.00% | Reduce -31.8% | 561,700 | $2.6M |
| Redmile Group, LLC | 0.22% | No change | 451,099 | $2.1M |
| Barclays PLC | 0.00% | Add +51.2% | 424,248 | $2.0M |
| Susquehanna International Group, LLP | 0.00% | Reduce -36.3% | 406,202 | $1.9M |
| Wellington Management Group LLP | 0.00% | Add +1.8% | 399,291 | $1.9M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -35.2% | 389,066 | $1.8M |
| Acadian Asset Management LLC | 0.00% | Add +2078.0% | 383,237 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Add +4.7% | 377,127 | $1.8M |
| Y-Intercept (Hong Kong) Ltd | 0.04% | Add +655.2% | 336,214 | $1.6M |
| FMR LLC | 0.00% | Add +4.8% | 326,420 | $1.5M |
| Voss Capital, LP | 0.10% | Add +16.3% | 319,800 | $1.5M |
| Squarepoint Ops LLC | 0.00% | Add +1679.1% | 284,567 | $1.3M |
| State of Wisconsin Investment Board | 0.00% | Add +1271.3% | 278,020 | $1.3M |
| Thompson Siegel & Walmsley LLC | 0.02% | Add +54.2% | 266,387 | $1.2M |
| IHT Wealth Management, LLC | 0.03% | Add +0.4% | 263,805 | $1.2M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | No change | 252,000 | $1.2M |
| Walleye Capital LLC | 0.01% | Reduce -64.8% | 243,275 | $1.1M |
| UBS Group AG | 0.00% | Reduce -73.6% | 227,865 | $1.1M |
| Tudor Investment Corporation | 0.01% | No change | 225,186 | $1.1M |
| Legato Capital Management LLC | 0.12% | Reduce -0.2% | 216,805 | $1.0M |
| Rhumbline Advisers | 0.00% | Add +12.2% | 215,691 | $1.0M |
| Raymond James Financial Inc. | 0.00% | Add +16.0% | 209,146 | $977K |
| Stonepine Capital Management, LLC | 0.94% | Add +100.6% | 205,100 | $958K |
| Brevan Howard Capital Management LP | 0.01% | Add +6.6% | 205,024 | $957K |
| Commonwealth Equity Services, LLC | 0.00% | Add +0.1% | 197,743 | $923K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -28.8% | 181,877 | $849K |
| Occudo Quantitative Strategies LP | 0.09% | Add +48.9% | 179,354 | $838K |
| Diversified Trust Co. | 0.02% | Reduce -3.1% | 170,235 | $795K |
| Quarry LP | 0.18% | Add +129.7% | 162,500 | $759K |
| Principal Financial Group Inc. | 0.00% | Add +35.3% | 153,937 | $719K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -13.1% | 153,271 | $716K |
| Alpine Global Management, LLC | 0.18% | Add +50.0% | 150,000 | $701K |
| Ameriprise Financial Inc. | 0.00% | Reduce -11.3% | 149,028 | $696K |
| Alliancebernstein L.P. | 0.00% | No change | 144,830 | $676K |
| Mackenzie Financial Corp. | 0.00% | Reduce -2.8% | 138,092 | $645K |
| Bantamac Capital, LLC | 0.22% | Add +56.3% | 132,994 | $621K |
| Polen Capital Management LLC | 0.00% | New | 132,994 | $621K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 132,382 | $618K |
| Man Group plc | 0.00% | Reduce -25.3% | 130,849 | $611K |
| Graham Capital Management, L.P. | 0.02% | Reduce -6.2% | 125,417 | $586K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -6.5% | 123,189 | $575K |
| Roundview Capital LLC | 0.04% | No change | 120,000 | $560K |
| Creative Planning | 0.00% | Add +10.3% | 117,755 | $550K |
| Sei Investments Co. | 0.00% | Add +19.5% | 116,534 | $544K |
| Brown Advisory Inc. | 0.00% | No change | 114,698 | $536K |
| Harvest Investment Services, LLC | 0.12% | Add +141.0% | 111,970 | $523K |
| Ieq Capital, LLC | 0.00% | Reduce -30.1% | 108,495 | $507K |
| Franklin Resources Inc. | 0.00% | Reduce -4.3% | 103,278 | $482K |
| Intech Investment Management LLC | 0.00% | Add +88.5% | 94,437 | $441K |
| Invesco Ltd. | 0.00% | Reduce -91.6% | 86,194 | $403K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -2.2% | 82,138 | $384K |
| Globeflex Capital L P | 0.03% | Reduce -35.8% | 80,431 | $376K |
| Orbimed Advisors LLC | 0.01% | No change | 80,420 | $376K |
| Wells Fargo & Company | 0.00% | Add +15.0% | 80,366 | $375K |
| Citigroup Inc. | 0.00% | Reduce -34.4% | 77,534 | $362K |
| Simplex Trading, LLC | 0.01% | New | 76,644 | $357K |
| EntryPoint Capital, LLC | 0.17% | Reduce -3.7% | 72,899 | $340K |
| STRS Ohio | 0.00% | Add +7.5% | 65,500 | $306K |
| GPS Wealth Strategies Group, LLC | 0.03% | Reduce -3.0% | 64,925 | $303K |
| Gsa Capital Partners LLP | 0.02% | Reduce -55.1% | 62,322 | $291K |
| Cwm, LLC | 0.00% | Reduce -17.7% | 55,111 | $257K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.0% | 54,472 | $254K |
| Chevy Chase Trust Holdings, LLC | 0.00% | No change | 51,243 | $239K |
| Weiss Asset Management LP | 0.00% | No change | 50,001 | $234K |
| Quadrature Capital Ltd | 0.00% | Add +50.2% | 46,756 | $219K |
| Cetera Investment Advisers | 0.00% | Add +3.9% | 46,332 | $216K |
| Point72 Asset Management | 0.00% | Reduce -49.0% | 45,100 | $211K |
| Royal Bank of Canada | 0.00% | Reduce -79.2% | 44,353 | $206K |
| New York State Common Retirement Fund | 0.00% | No change | 43,422 | $203K |
| LPL Financial LLC | 0.00% | Add +10.9% | 43,052 | $201K |
| Quantbot Technologies LP | 0.01% | Reduce -20.6% | 42,945 | $201K |
| Osaic Holdings, Inc. | 0.00% | Add +9.7% | 42,709 | $199K |
| LJI Wealth Management, LLC | 0.03% | No change | 42,350 | $198K |
| Profund Advisors LLC | 0.01% | Add +108.4% | 42,080 | $197K |
| Voya Investment Management LLC | 0.00% | Add +4.0% | 41,390 | $193K |
| Savvy Advisors, Inc. | 0.01% | New | 40,465 | $189K |
| Centiva Capital, LP | 0.01% | Reduce -37.0% | 39,086 | $183K |
| Engineers Gate Manager LP | 0.00% | New | 38,040 | $178K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 37,970 | $177K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 37,619 | $176K |
| ProShare Advisors LLC | 0.00% | Reduce -1.0% | 36,723 | $171K |
| State of Wyoming | 0.02% | New | 35,206 | $164K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.3% | 34,642 | $162K |
| Gotham Asset Management | 0.00% | Add +101.9% | 32,766 | $153K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +7.6% | 32,167 | $150K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 31,659 | $148K |
| Jane Street Group, LLC | 0.00% | Reduce -96.2% | 31,165 | $146K |
| Cerity Partners LLC | 0.00% | Reduce -11.7% | 28,128 | $131K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -14.4% | 26,758 | $127K |
| Asset Management Group, Inc. | 0.02% | No change | 26,480 | $124K |
| Rafferty Asset Management, LLC | 0.00% | Add +72.7% | 25,903 | $121K |
| Janney Montgomery Scott LLC | 0.00% | New | 25,200 | $118K |
| XTX Topco Ltd | 0.00% | Reduce -88.6% | 24,662 | $115K |
| Sherbrooke Park Advisers LLC | 0.05% | Add +63.5% | 24,325 | $114K |
| Apollon Wealth Management, LLC | 0.00% | Add +0.2% | 24,201 | $113K |
| Deerfield Management Company, L.P. | 0.00% | New | 22,574 | $105K |
| Catalyst Funds Management Pty Ltd | 0.03% | New | 21,645 | $101K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -55.9% | 21,274 | $99K |
| Sunpointe, LLC | 0.04% | No change | 21,000 | $98K |
| Nebula Research & Development LLC | 0.01% | New | 20,751 | $97K |
| Los Angeles Capital Management LLC | 0.00% | New | 20,382 | $95K |
| SG Americas Securities, LLC | 0.00% | Reduce -72.6% | 19,293 | $90K |
| Cibc World Markets Corp. | 0.00% | Reduce -40.6% | 18,473 | $86K |
| Atom Investors LP | 0.01% | New | 18,155 | $85K |
| Modern Wealth Management, LLC | 0.00% | New | 17,704 | $83K |
| Victory Capital Management Inc. | 0.00% | Add +2.8% | 17,608 | $82K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +913.1% | 17,395 | $81K |
| Van Hulzen Asset Management, LLC | 0.01% | Add +5.2% | 17,124 | $80K |
| Susquehanna Fundamental Investments, LLC | 0.00% | No change | 17,087 | $80K |
| BNP Paribas Financial Markets | 0.00% | Reduce -95.3% | 16,310 | $76K |
| Landscape Capital Management, L.L.C. | 0.01% | No change | 15,709 | $73K |
| Prelude Capital Management, LLC | 0.01% | New | 15,500 | $72K |
| Summit Securities Group LLC | 0.02% | New | 14,497 | $68K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 14,205 | $66K |
| Veery Capital, LLC | 0.02% | No change | 14,163 | $66K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.00% | No change | 13,650 | $64K |
| Quantinno Capital Management LP | 0.00% | New | 12,571 | $59K |
| Mariner, LLC | 0.00% | Reduce -71.6% | 11,737 | $55K |
| Inceptionr LLC | 0.01% | Reduce -56.1% | 11,639 | $54K |
| Xponance LLC | 0.00% | Add +11.1% | 11,460 | $54K |
| Pallas Capital Advisors LLC | 0.00% | Reduce -28.3% | 11,005 | $51K |
| Captrust Financial Advisors | 0.00% | Reduce -8.3% | 10,806 | $50K |
| California State Teachers Retirement System | 0.00% | No change | 10,161 | $47K |
| Apella Capital, LLC | 0.00% | No change | 10,000 | $47K |
| Sigma Planning Corp | 0.00% | Reduce -86.4% | 10,050 | $47K |
| CIBC Private Wealth Group LLC | 0.00% | No change | 6,664 | $31K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | Reduce -76.9% | 6,300 | $29K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +24.0% | 6,187 | $29K |
| Amalgamated Bank | 0.00% | No change | 4,834 | $23K |
| GF Fund Management Co. LTD. | 0.00% | No change | 3,817 | $18K |
| Truvestments Capital LLC | 0.00% | New | 3,573 | $17K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -10.0% | 3,299 | $15K |
| Webster Bank, N. A. | 0.00% | No change | 3,000 | $14K |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 2,789 | $13K |
| Nisa Investment Advisors, LLC | 0.00% | Add +206.5% | 2,204 | $10K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +54.5% | 2,191 | $10K |
| Allworth Financial LP | 0.00% | Add +9.5% | 2,076 | $10K |
| SBI Securities Co., Ltd. | 0.00% | No change | 1,907 | $9K |
| Creative Financial Designs Inc. | 0.00% | Reduce -7.5% | 1,900 | $9K |
| Point72 (DIFC) Ltd | 0.00% | New | 1,627 | $8K |
| Fortitude Family Office, LLC | 0.00% | Reduce -7.1% | 1,553 | $7K |
| Jones Financial Companies LLLP | 0.00% | New | 1,478 | $7K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +365.5% | 1,336 | $6K |
| Hillsdale Investment Management Inc. | 0.00% | Add +18.2% | 1,300 | $6K |
| Tsfg, LLC | 0.00% | No change | 1,058 | $5K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 1,067 | $5K |
| Essential Partners LLC | 0.00% | — | 1,065 | $5K |
| Headlands Technologies LLC | 0.00% | New | 1,052 | $5K |
| Activest Wealth Management | 0.00% | No change | 1,000 | $5K |
| Glenmede Investment Management, LP | 0.00% | — | 975 | $5K |
| True Wealth Design, LLC | 0.00% | Reduce -19.8% | 967 | $5K |
| Global Retirement Partners, LLC | 0.00% | — | 700 | $3K |
| Signaturefd, LLC | 0.00% | Add +61.4% | 631 | $3K |
| PNC Financial Services Group, Inc. | 0.00% | Add +482.4% | 594 | $3K |
| Clearstead Advisors, LLC | 0.00% | New | 564 | $3K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +31.9% | 554 | $3K |
| Daiwa Securities Group Inc. | 0.00% | No change | 404 | $2K |
| Rothschild Investment LLC | 0.00% | No change | 420 | $2K |
| Sterling Capital Management LLC | 0.00% | Add +154.9% | 362 | $2K |
| Covestor Ltd | 0.00% | Reduce -22.7% | 293 | $1K |
| Spurstone Advisory Services, LLC | 0.01% | No change | 200 | $934 |
| Farther Finance Advisors, LLC | 0.00% | No change | 181 | $845 |
| Parkside Financial Bank & Trust | 0.00% | No change | 155 | $724 |
| IFP Advisors, Inc | 0.00% | Add +207.7% | 80 | $374 |
| WealthTrak Capital Management LLC | 0.00% | No change | 40 | $187 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 40 | $187 |
"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.