Xeris Biopharma HoldingsXERS

13F holders, Q2 2025 (June 30)
200holders +1
23new positions
24sold out
7famous investors
$4.67avg. 13F price*

At the end of Q2 2025, 200 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 1 from Q1 2025. 23 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($53.9M), Vanguard Group Inc. ($45.8M) and D. E. Shaw & Co. ($17.9M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Xeris Biopharma Holdings Inc.
CUSIP
98422E103
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 142Q1 2024Q2 2024: 135Q2 2024Q3 2024: 144Q3 2024Q4 2024: 162Q4 2024Q1 2025: 199Q1 2025Q2 2025: 200Q2 2025Q3 2025: 230Q3 2025Q4 2025: 224Q4 2025Q1 2026: 237Q1 2026Q2 2026: 240Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions23$3.2M
Exits24$14.5M

All 13F filers, Q1 2025 → Q2 2025: 13,969,335 shares bought and 11,099,696 shares sold, net +2,869,639 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 200 holders

BlackRock, Inc. 0.00% Add +6.9% 11,536,321 $53.9M
Vanguard Group Inc. 0.00% Add +21.1% 9,816,937 $45.8M
D. E. Shaw & Co. 0.02% Add +25.6% 3,835,407 $17.9M
State Street Corp. 0.00% Add +13.8% 3,783,200 $17.7M
Geode Capital Management, LLC 0.00% Add +7.2% 3,650,688 $17.1M
Morgan Stanley 0.00% Reduce -15.1% 3,642,584 $17.0M
Qube Research & Technologies Ltd 0.02% Add +67.5% 3,089,771 $14.4M
Millennium Management 0.01% Add +26.6% 2,933,620 $13.7M
Nuveen, LLC 0.00% Add +16.6% 2,600,442 $12.1M
Goldman Sachs Group Inc. 0.00% Reduce -18.6% 2,271,486 $10.6M
Rosalind Advisors, Inc. 4.87% Reduce -13.6% 2,155,594 $10.1M
Parkman Healthcare Partners LLC 1.14% Add +18.4% 2,107,483 $9.8M
Driehaus Capital Management LLC 0.08% Add +46.7% 2,071,075 $9.7M
Renaissance Technologies 0.01% Reduce -5.0% 2,055,340 $9.6M
Legal & General Group Plc 0.00% Add +27.8% 1,804,203 $8.4M
Bank of America Corp. 0.00% Reduce -2.7% 1,663,490 $7.8M
CenterBook Partners LP 0.41% Add +237.7% 1,594,229 $7.4M
Prudential Financial Inc. 0.01% Add +41.7% 1,556,629 $7.3M
Northern Trust Corp. 0.00% Add +7.7% 1,293,530 $6.0M
Connor, Clark & Lunn Investment Management Ltd. 0.02% Add +108.3% 1,227,959 $5.7M
Two Sigma Investments, LP 0.01% Add +36.4% 1,214,699 $5.7M
Knott David M Jr 2.24% Reduce -4.5% 1,060,000 $5.0M
Two Sigma Advisers, LP 0.01% Add +14.2% 1,056,779 $4.9M
AQR Capital Management 0.00% Add +10.8% 1,048,993 $4.9M
JPMorgan Chase & Co. 0.00% Reduce -51.2% 1,032,262 $4.8M
Voloridge Investment Management, LLC 0.02% Reduce -26.4% 994,381 $4.6M
Cubist Systematic Strategies, LLC 0.04% Add +8.5% 880,314 $4.1M
Kennedy Capital Management LLC 0.09% Add +11.0% 816,147 $3.8M
Jump Financial, LLC 0.04% Add +78.6% 756,403 $3.5M
Deutsche Bank AG 0.00% Reduce -2.6% 736,927 $3.4M
Essex Investment Management Co. LLC 0.62% Reduce -0.6% 725,774 $3.4M
Federated Hermes, Inc. 0.01% Add +0.5% 691,381 $3.2M
Informed Momentum Co LLC 0.42% Reduce -37.2% 586,865 $2.7M
Charles Schwab Investment Management Inc. 0.00% Add +33.9% 567,538 $2.7M
Norges Bank 0.00% Reduce -31.8% 561,700 $2.6M
Redmile Group, LLC 0.22% No change 451,099 $2.1M
Barclays PLC 0.00% Add +51.2% 424,248 $2.0M
Susquehanna International Group, LLP 0.00% Reduce -36.3% 406,202 $1.9M
Wellington Management Group LLP 0.00% Add +1.8% 399,291 $1.9M
Schonfeld Strategic Advisors LLC 0.01% Reduce -35.2% 389,066 $1.8M
Acadian Asset Management LLC 0.00% Add +2078.0% 383,237 $1.8M
Bank of New York Mellon Corp 0.00% Add +4.7% 377,127 $1.8M
Y-Intercept (Hong Kong) Ltd 0.04% Add +655.2% 336,214 $1.6M
FMR LLC 0.00% Add +4.8% 326,420 $1.5M
Voss Capital, LP 0.10% Add +16.3% 319,800 $1.5M
Squarepoint Ops LLC 0.00% Add +1679.1% 284,567 $1.3M
State of Wisconsin Investment Board 0.00% Add +1271.3% 278,020 $1.3M
Thompson Siegel & Walmsley LLC 0.02% Add +54.2% 266,387 $1.2M
IHT Wealth Management, LLC 0.03% Add +0.4% 263,805 $1.2M
Healthcare of Ontario Pension Plan Trust Fund 0.00% No change 252,000 $1.2M
Walleye Capital LLC 0.01% Reduce -64.8% 243,275 $1.1M
UBS Group AG 0.00% Reduce -73.6% 227,865 $1.1M
Tudor Investment Corporation 0.01% No change 225,186 $1.1M
Legato Capital Management LLC 0.12% Reduce -0.2% 216,805 $1.0M
Rhumbline Advisers 0.00% Add +12.2% 215,691 $1.0M
Raymond James Financial Inc. 0.00% Add +16.0% 209,146 $977K
Stonepine Capital Management, LLC 0.94% Add +100.6% 205,100 $958K
Brevan Howard Capital Management LP 0.01% Add +6.6% 205,024 $957K
Commonwealth Equity Services, LLC 0.00% Add +0.1% 197,743 $923K
Jacobs Levy Equity Management, Inc. 0.00% Reduce -28.8% 181,877 $849K
Occudo Quantitative Strategies LP 0.09% Add +48.9% 179,354 $838K
Diversified Trust Co. 0.02% Reduce -3.1% 170,235 $795K
Quarry LP 0.18% Add +129.7% 162,500 $759K
Principal Financial Group Inc. 0.00% Add +35.3% 153,937 $719K
T. Rowe Price Associates Inc. 0.00% Reduce -13.1% 153,271 $716K
Alpine Global Management, LLC 0.18% Add +50.0% 150,000 $701K
Ameriprise Financial Inc. 0.00% Reduce -11.3% 149,028 $696K
Alliancebernstein L.P. 0.00% No change 144,830 $676K
Mackenzie Financial Corp. 0.00% Reduce -2.8% 138,092 $645K
Bantamac Capital, LLC 0.22% Add +56.3% 132,994 $621K
Polen Capital Management LLC 0.00% New 132,994 $621K
Campbell & CO Investment Adviser LLC 0.04% New 132,382 $618K
Man Group plc 0.00% Reduce -25.3% 130,849 $611K
Graham Capital Management, L.P. 0.02% Reduce -6.2% 125,417 $586K
Russell Investments Group, Ltd. 0.00% Reduce -6.5% 123,189 $575K
Roundview Capital LLC 0.04% No change 120,000 $560K
Creative Planning 0.00% Add +10.3% 117,755 $550K
Sei Investments Co. 0.00% Add +19.5% 116,534 $544K
Brown Advisory Inc. 0.00% No change 114,698 $536K
Harvest Investment Services, LLC 0.12% Add +141.0% 111,970 $523K
Ieq Capital, LLC 0.00% Reduce -30.1% 108,495 $507K
Franklin Resources Inc. 0.00% Reduce -4.3% 103,278 $482K
Intech Investment Management LLC 0.00% Add +88.5% 94,437 $441K
Invesco Ltd. 0.00% Reduce -91.6% 86,194 $403K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -2.2% 82,138 $384K
Globeflex Capital L P 0.03% Reduce -35.8% 80,431 $376K
Orbimed Advisors LLC 0.01% No change 80,420 $376K
Wells Fargo & Company 0.00% Add +15.0% 80,366 $375K
Citigroup Inc. 0.00% Reduce -34.4% 77,534 $362K
Simplex Trading, LLC 0.01% New 76,644 $357K
EntryPoint Capital, LLC 0.17% Reduce -3.7% 72,899 $340K
STRS Ohio 0.00% Add +7.5% 65,500 $306K
GPS Wealth Strategies Group, LLC 0.03% Reduce -3.0% 64,925 $303K
Gsa Capital Partners LLP 0.02% Reduce -55.1% 62,322 $291K
Cwm, LLC 0.00% Reduce -17.7% 55,111 $257K
Manufacturers Life Insurance Company, The 0.00% Add +7.0% 54,472 $254K
Chevy Chase Trust Holdings, LLC 0.00% No change 51,243 $239K
Weiss Asset Management LP 0.00% No change 50,001 $234K
Quadrature Capital Ltd 0.00% Add +50.2% 46,756 $219K
Cetera Investment Advisers 0.00% Add +3.9% 46,332 $216K
Point72 Asset Management 0.00% Reduce -49.0% 45,100 $211K
Royal Bank of Canada 0.00% Reduce -79.2% 44,353 $206K
New York State Common Retirement Fund 0.00% No change 43,422 $203K
LPL Financial LLC 0.00% Add +10.9% 43,052 $201K
Quantbot Technologies LP 0.01% Reduce -20.6% 42,945 $201K
Osaic Holdings, Inc. 0.00% Add +9.7% 42,709 $199K
LJI Wealth Management, LLC 0.03% No change 42,350 $198K
Profund Advisors LLC 0.01% Add +108.4% 42,080 $197K
Voya Investment Management LLC 0.00% Add +4.0% 41,390 $193K
Savvy Advisors, Inc. 0.01% New 40,465 $189K
Centiva Capital, LP 0.01% Reduce -37.0% 39,086 $183K
Engineers Gate Manager LP 0.00% New 38,040 $178K
State Board of Administration of Florida Retirement System 0.00% No change 37,970 $177K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 37,619 $176K
ProShare Advisors LLC 0.00% Reduce -1.0% 36,723 $171K
State of Wyoming 0.02% New 35,206 $164K
Cambridge Investment Research Advisors, Inc. 0.00% Add +0.3% 34,642 $162K
Gotham Asset Management 0.00% Add +101.9% 32,766 $153K
China Universal Asset Management Co., Ltd. 0.01% Add +7.6% 32,167 $150K
Police & Firemen's Retirement System of New Jersey 0.00% No change 31,659 $148K
Jane Street Group, LLC 0.00% Reduce -96.2% 31,165 $146K
Cerity Partners LLC 0.00% Reduce -11.7% 28,128 $131K
Wealth Enhancement Advisory Services, LLC 0.00% Reduce -14.4% 26,758 $127K
Asset Management Group, Inc. 0.02% No change 26,480 $124K
Rafferty Asset Management, LLC 0.00% Add +72.7% 25,903 $121K
Janney Montgomery Scott LLC 0.00% New 25,200 $118K
XTX Topco Ltd 0.00% Reduce -88.6% 24,662 $115K
Sherbrooke Park Advisers LLC 0.05% Add +63.5% 24,325 $114K
Apollon Wealth Management, LLC 0.00% Add +0.2% 24,201 $113K
Deerfield Management Company, L.P. 0.00% New 22,574 $105K
Catalyst Funds Management Pty Ltd 0.03% New 21,645 $101K
Virtus Investment Advisers, LLC 0.03% Reduce -55.9% 21,274 $99K
Sunpointe, LLC 0.04% No change 21,000 $98K
Nebula Research & Development LLC 0.01% New 20,751 $97K
Los Angeles Capital Management LLC 0.00% New 20,382 $95K
SG Americas Securities, LLC 0.00% Reduce -72.6% 19,293 $90K
Cibc World Markets Corp. 0.00% Reduce -40.6% 18,473 $86K
Atom Investors LP 0.01% New 18,155 $85K
Modern Wealth Management, LLC 0.00% New 17,704 $83K
Victory Capital Management Inc. 0.00% Add +2.8% 17,608 $82K
Tower Research Capital LLC (TRC) 0.00% Add +913.1% 17,395 $81K
Van Hulzen Asset Management, LLC 0.01% Add +5.2% 17,124 $80K
Susquehanna Fundamental Investments, LLC 0.00% No change 17,087 $80K
BNP Paribas Financial Markets 0.00% Reduce -95.3% 16,310 $76K
Landscape Capital Management, L.L.C. 0.01% No change 15,709 $73K
Prelude Capital Management, LLC 0.01% New 15,500 $72K
Summit Securities Group LLC 0.02% New 14,497 $68K
Ameritas Investment Partners, Inc. 0.00% No change 14,205 $66K
Veery Capital, LLC 0.02% No change 14,163 $66K
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 0.00% No change 13,650 $64K
Quantinno Capital Management LP 0.00% New 12,571 $59K
Mariner, LLC 0.00% Reduce -71.6% 11,737 $55K
Inceptionr LLC 0.01% Reduce -56.1% 11,639 $54K
Xponance LLC 0.00% Add +11.1% 11,460 $54K
Pallas Capital Advisors LLC 0.00% Reduce -28.3% 11,005 $51K
Captrust Financial Advisors 0.00% Reduce -8.3% 10,806 $50K
California State Teachers Retirement System 0.00% No change 10,161 $47K
Apella Capital, LLC 0.00% No change 10,000 $47K
Sigma Planning Corp 0.00% Reduce -86.4% 10,050 $47K
CIBC Private Wealth Group LLC 0.00% No change 6,664 $31K
Point72 Asia (Singapore) Pte. Ltd. 0.01% Reduce -76.9% 6,300 $29K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +24.0% 6,187 $29K
Amalgamated Bank 0.00% No change 4,834 $23K
GF Fund Management Co. LTD. 0.00% No change 3,817 $18K
Truvestments Capital LLC 0.00% New 3,573 $17K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -10.0% 3,299 $15K
Webster Bank, N. A. 0.00% No change 3,000 $14K
Northwestern Mutual Wealth Management Co. 0.00% No change 2,789 $13K
Nisa Investment Advisors, LLC 0.00% Add +206.5% 2,204 $10K
EverSource Wealth Advisors, LLC 0.00% Add +54.5% 2,191 $10K
Allworth Financial LP 0.00% Add +9.5% 2,076 $10K
SBI Securities Co., Ltd. 0.00% No change 1,907 $9K
Creative Financial Designs Inc. 0.00% Reduce -7.5% 1,900 $9K
Point72 (DIFC) Ltd 0.00% New 1,627 $8K
Fortitude Family Office, LLC 0.00% Reduce -7.1% 1,553 $7K
Jones Financial Companies LLLP 0.00% New 1,478 $7K
Caitong International Asset Management Co., Ltd 0.00% Add +365.5% 1,336 $6K
Hillsdale Investment Management Inc. 0.00% Add +18.2% 1,300 $6K
Tsfg, LLC 0.00% No change 1,058 $5K
Aster Capital Management (DIFC) Ltd 0.00% New 1,067 $5K
Essential Partners LLC 0.00% — 1,065 $5K
Headlands Technologies LLC 0.00% New 1,052 $5K
Activest Wealth Management 0.00% No change 1,000 $5K
Glenmede Investment Management, LP 0.00% — 975 $5K
True Wealth Design, LLC 0.00% Reduce -19.8% 967 $5K
Global Retirement Partners, LLC 0.00% — 700 $3K
Signaturefd, LLC 0.00% Add +61.4% 631 $3K
PNC Financial Services Group, Inc. 0.00% Add +482.4% 594 $3K
Clearstead Advisors, LLC 0.00% New 564 $3K
MassMutual Private Wealth & Trust, FSB 0.00% Add +31.9% 554 $3K
Daiwa Securities Group Inc. 0.00% No change 404 $2K
Rothschild Investment LLC 0.00% No change 420 $2K
Sterling Capital Management LLC 0.00% Add +154.9% 362 $2K
Covestor Ltd 0.00% Reduce -22.7% 293 $1K
Spurstone Advisory Services, LLC 0.01% No change 200 $934
Farther Finance Advisors, LLC 0.00% No change 181 $845
Parkside Financial Bank & Trust 0.00% No change 155 $724
IFP Advisors, Inc 0.00% Add +207.7% 80 $374
WealthTrak Capital Management LLC 0.00% No change 40 $187
Wilmington Savings Fund Society, FSB 0.00% No change 40 $187

"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.