Apogee TherapeuticsAPGE

13F holders, Q4 2024 (December 31)
157holders +18
30new positions
20sold out
5famous investors
$45.30avg. 13F price*

At the end of Q4 2024, 157 institutions reported holding Apogee Therapeutics Inc. (APGE) in their 13F filings, up 18 from Q3 2024. 30 opened new positions and 20 sold out. The largest holders were Venrock Adviser, LLC ($384.7M), FMR LLC ($339.7M) and Wellington Management Group LLP ($204.6M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Apogee Therapeutics Inc.
CUSIP
03770N101
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 139Q1 2024Q2 2024: 139Q2 2024Q3 2024: 139Q3 2024Q4 2024: 157Q4 2024Q1 2025: 168Q1 2025Q2 2025: 182Q2 2025Q3 2025: 174Q3 2025Q4 2025: 207Q4 2025Q1 2026: 224Q1 2026Q2 2026: 288Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions30$132.7M
Exits20$103.2M

All 13F filers, Q3 2024 → Q4 2024: 6,951,947 shares bought and 4,798,610 shares sold, net +2,153,337 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 157 holders

Venrock Adviser, LLC 26.40% No change 8,493,321 $384.7M
FMR LLC 0.02% Reduce -0.0% 7,499,382 $339.7M
Wellington Management Group LLP 0.04% Reduce -6.2% 4,517,363 $204.6M
BlackRock, Inc. 0.00% Add +2.3% 3,044,958 $137.9M
RTW Investments, LP 1.86% Add +0.0% 2,712,097 $122.9M
Driehaus Capital Management LLC 0.97% Add +2.8% 2,605,310 $118.0M
Vanguard Group Inc. 0.00% Reduce -1.4% 2,097,597 $95.0M
Fairmount Funds Management LLC 9.23% No change 2,048,647 $92.8M
Ra Capital Management, L.P. 0.95% Reduce -20.0% 1,569,491 $71.1M
Braidwell LP 3.12% Reduce -6.3% 1,540,362 $69.8M
State Street Corp. 0.00% Add +3.9% 1,467,114 $66.5M
Alliancebernstein L.P. 0.02% Add +13.5% 1,355,185 $61.4M
Paradigm Biocapital Advisors LP 2.02% Add +82.9% 1,283,766 $58.2M
Janus Henderson Group PLC 0.03% Add +141.7% 1,135,100 $51.5M
T. Rowe Price Associates Inc. 0.01% Add +38.9% 1,052,595 $47.7M
Perceptive Advisors LLC 1.32% Reduce -48.0% 1,047,232 $47.4M
Woodline Partners LP 0.31% Add +4.0% 1,015,608 $46.0M
Affinity Asset Advisors, LLC 7.17% Add +40.3% 931,728 $42.2M
Jefferies Financial Group Inc. 0.46% Add +140.4% 887,497 $40.2M
Franklin Resources Inc. 0.01% Add +0.6% 866,188 $39.2M
Geode Capital Management, LLC 0.00% Reduce -0.9% 816,113 $37.0M
Siren, L.L.C. 1.50% New 747,325 $33.9M
Mercer Global Advisors Inc. 0.08% New 720,101 $32.6M
UBS Group AG 0.01% Add +944.5% 541,286 $24.5M
Barclays PLC 0.01% Add +30.6% 476,760 $21.6M
Goldman Sachs Group Inc. 0.00% Add +159.1% 408,019 $18.5M
Northern Trust Corp. 0.00% Add +6.8% 327,292 $14.8M
Jennison Associates LLC 0.01% Reduce -0.1% 312,391 $14.2M
Point72 Asset Management 0.04% Reduce -57.2% 302,735 $13.7M
Logos Global Management LP 1.59% New 300,000 $13.6M
Commodore Capital LP 0.96% No change 290,000 $13.1M
Charles Schwab Investment Management Inc. 0.00% Reduce -1.1% 277,492 $12.6M
Two Sigma Investments, LP 0.03% Add +33.7% 266,482 $12.1M
First Turn Management, LLC 2.05% New 252,725 $11.4M
Adage Capital Partners Gp, L.L.C. 0.02% New 240,200 $10.9M
Victory Capital Management Inc. 0.01% Reduce -35.6% 223,062 $10.1M
Morgan Stanley 0.00% Reduce -12.1% 209,534 $9.5M
Capital World Investors 0.00% New 205,100 $9.3M
Frontier Capital Management Co. LLC 0.07% Reduce -44.5% 172,711 $7.8M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% — 143,952 $6.5M
Nuveen Asset Management, LLC 0.00% Add +1.8% 137,826 $6.2M
Millennium Management 0.01% Add +44.6% 130,171 $5.9M
TD Asset Management Inc 0.01% Add +35.3% 126,446 $5.7M
Bank of New York Mellon Corp 0.00% Reduce -1.6% 110,827 $5.0M
ArrowMark Colorado Holdings LLC 0.07% No change 109,410 $5.0M
Bank of America Corp. 0.00% Reduce -64.8% 105,540 $4.8M
Allostery Investments LP 8.89% — 100,000 $4.5M
Tang Capital Management LLC 0.30% No change 100,000 $4.5M
Platinum Investment Management Ltd. 0.25% Reduce -11.2% 95,646 $4.3M
Granahan Investment Management, LLC 0.18% Add +1.2% 92,854 $4.2M
Cubist Systematic Strategies, LLC 0.07% Add +8.6% 91,213 $4.1M
Manufacturers Life Insurance Company, The 0.00% Add +29.4% 87,953 $4.0M
Boxer Capital Management, LLC 0.33% — 86,000 $3.9M
Candriam S.C.A. 0.02% Reduce -4.8% 85,661 $3.9M
Parkman Healthcare Partners LLC 0.51% New 85,000 $3.9M
Blackstone Inc. 0.02% No change 80,000 $3.6M
Marshall Wace, LLP 0.00% Add +1963.9% 75,849 $3.4M
Citadel Advisors 0.00% New 72,724 $3.3M
Kennedy Capital Management LLC 0.07% Add +75.5% 72,307 $3.3M
Two Sigma Advisers, LP 0.01% Add +51.5% 71,500 $3.2M
Schonfeld Strategic Advisors LLC 0.02% New 70,766 $3.2M
Soleus Capital Management, L.P. 0.24% New 70,000 $3.2M
Ensign Peak Advisors, Inc 0.01% No change 69,750 $3.2M
Rafferty Asset Management, LLC 0.01% Add +5.7% 57,673 $2.6M
Schroder Investment Management Group 0.00% No change 58,466 $2.6M
Citigroup Inc. 0.00% Add +99.4% 56,102 $2.5M
Rhumbline Advisers 0.00% Add +3.4% 52,720 $2.4M
Diadema Partners LP 2.58% — 50,620 $2.3M
Voya Investment Management LLC 0.00% Reduce -18.7% 45,960 $2.1M
Swiss National Bank 0.00% Add +17.5% 44,300 $2.0M
HighVista Strategies LLC 0.73% Reduce -30.1% 43,190 $2.0M
ADAR1 Capital Management, LLC 0.40% Reduce -27.8% 41,274 $1.9M
Voloridge Investment Management, LLC 0.01% Reduce -1.5% 41,106 $1.9M
Neo Ivy Capital Management 0.35% New 38,523 $1.7M
JPMorgan Chase & Co. 0.00% Add +26.1% 37,255 $1.7M
Alps Advisors Inc. 0.01% Add +2.6% 36,410 $1.6M
Squarepoint Ops LLC 0.00% Add +90.8% 36,344 $1.6M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +0.1% 32,261 $1.5M
Deutsche Bank AG 0.00% Add +50.9% 31,739 $1.4M
Susquehanna International Group, LLP 0.00% Reduce -39.3% 31,288 $1.4M
Legal & General Group Plc 0.00% Add +24.0% 25,873 $1.2M
Prudential Financial Inc. 0.00% No change 24,535 $1.1M
Erste Asset Management GmbH 0.01% New 24,000 $1.1M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.1% 23,835 $1.1M
Readystate Asset Management LP 0.08% New 23,400 $1.1M
MetLife Investment Management, LLC 0.01% Add +8.7% 22,960 $1.0M
Point72 (DIFC) Ltd 0.09% Add +15.5% 22,191 $1.0M
California State Teachers Retirement System 0.00% Add +13.1% 22,178 $1.0M
Invesco Ltd. 0.00% Reduce -83.9% 21,256 $963K
Jump Financial, LLC 0.02% New 20,867 $945K
Comerica Bank 0.00% Reduce -26.8% 20,540 $930K
Verition Fund Management LLC 0.00% New 19,477 $882K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 18,839 $853K
Wells Fargo & Company 0.00% Reduce -82.0% 17,705 $802K
Intech Investment Management LLC 0.01% Add +232.0% 16,934 $767K
Persistent Asset Partners Ltd 0.64% — 17,940 $742K
B Group, Inc. 0.42% — 15,000 $680K
Natixis Advisors, LLC 0.00% Reduce -1.3% 14,778 $669K
State of Wisconsin Investment Board 0.00% Add +63.5% 13,393 $607K
ProShare Advisors LLC 0.00% Add +30.4% 12,805 $580K
New York State Common Retirement Fund 0.00% Add +8.9% 12,187 $552K
Teachers Retirement System of the State of Kentucky 0.00% No change 11,644 $527K
Profund Advisors LLC 0.02% Add +2.9% 11,436 $518K
SG Americas Securities, LLC 0.00% Add +22.2% 9,890 $448K
D. E. Shaw & Co. 0.00% Reduce -80.2% 9,813 $445K
China Universal Asset Management Co., Ltd. 0.04% Add +10.3% 9,547 $432K
State Board of Administration of Florida Retirement System 0.00% No change 9,350 $424K
Police & Firemen's Retirement System of New Jersey 0.00% — 8,126 $368K
Global Endowment Management, LP 0.05% No change 7,797 $353K
Handelsbanken Fonder AB 0.00% Reduce -14.8% 7,500 $340K
Family Manage LLC 0.05% Reduce -13.2% 7,013 $318K
Allianz Asset Management GmbH 0.00% New 6,900 $313K
Teacher Retirement System of Texas 0.00% Add +38.2% 6,689 $303K
Arizona State Retirement System 0.00% Add +17.3% 6,517 $295K
XTX Topco Ltd 0.02% New 6,348 $288K
Tower Research Capital LLC (TRC) 0.01% Add +356.6% 6,287 $285K
Glenmede Trust Co. NA 0.00% No change 5,923 $268K
Ameriprise Financial Inc. 0.00% New 5,710 $259K
AlphaCentric Advisors LLC 0.26% Reduce -33.5% 5,649 $256K
Jane Street Group, LLC 0.00% Reduce -69.7% 5,568 $252K
STRS Ohio 0.00% Reduce -9.8% 5,500 $249K
AQR Capital Management 0.00% New 5,365 $243K
KLP Kapitalforvaltning As 0.00% — 5,000 $227K
Commonwealth Equity Services, LLC 0.00% New 4,906 $222K
BNP Paribas Financial Markets 0.00% New 4,824 $219K
Aigen Investment Management, LP 0.04% New 4,767 $216K
Optimize Financial Inc. 0.15% — 4,473 $203K
Ameritas Investment Partners, Inc. 0.01% No change 3,839 $174K
Virtus Advisers, LLC 0.03% Reduce -25.0% 1,604 $73K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.9% 1,500 $69K
Group One Trading LLC 0.00% Add +97.6% 1,324 $60K
Amalgamated Bank 0.00% No change 1,251 $57K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 1,207 $55K
GF Fund Management Co. LTD. 0.00% — 945 $43K
Royal Bank of Canada 0.00% Reduce -82.4% 776 $35K
Nisa Investment Advisors, LLC 0.00% Add +2.4% 428 $19K
Russell Investments Group, Ltd. 0.00% No change 188 $9K
Daiwa Securities Group Inc. 0.00% No change 171 $8K
GAMMA Investing LLC 0.00% Add +362.5% 148 $7K
Washington Trust Advisors, Inc. 0.00% No change 96 $4K
Red Tortoise LLC 0.00% No change 94 $4K
Aster Capital Management (DIFC) Ltd 0.00% New 90 $4K
Smartleaf Asset Management LLC 0.00% New 82 $4K
Simplex Trading, LLC 0.00% Add +92.1% 73 $3K
Caitong International Asset Management Co., Ltd 0.00% — 41 $2K
Sterling Capital Management LLC 0.00% Add +5.4% 39 $2K
Bellevue Asset Management, LLC 0.00% No change 36 $2K
Rothschild Investment LLC 0.00% Reduce -28.6% 25 $1K
Cwm, LLC 0.00% Reduce -44.1% 19 $1K
Osaic Holdings, Inc. 0.00% Reduce -46.1% 14 $634
Amundi 0.00% New 12 $591
EverSource Wealth Advisors, LLC 0.00% New 11 $498
Lindbrook Capital, LLC 0.00% New 11 $498
Federation des caisses Desjardins du Quebec 0.00% New 10 $453
Parallel Advisors, LLC 0.00% Reduce -45.5% 6 $272
US Bancorp \de 0.00% New 5 $227
Covestor Ltd 0.00% No change 3 $0

"% of holder's portfolio" is APGE's weight in each manager's 13F, not the share of Apogee Therapeutics Inc. the manager owns.