Edgewise TherapeuticsEWTX

13F holders, Q2 2026 (June 30)
226holders +12
38new positions
27sold out
5famous investors
$40.46avg. 13F price*

At the end of Q2 2026, 226 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, up 12 from Q1 2026. 38 opened new positions and 27 sold out. The largest holders were Orbimed Advisors LLC ($630.5M), Paradigm Biocapital Advisors LP ($415.1M) and Ra Capital Management, L.P. ($341.0M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Edgewise Therapeutics Inc.
CUSIP
28036F105
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 129Q1 2024Q2 2024: 140Q2 2024Q3 2024: 177Q3 2024Q4 2024: 200Q4 2024Q1 2025: 192Q1 2025Q2 2025: 178Q2 2025Q3 2025: 173Q3 2025Q4 2025: 199Q4 2025Q1 2026: 214Q1 2026Q2 2026: 226Q2 2026

Total Exit/New Position Q1 2026 → Q2 2026

InstitutionsTotal Value
New Positions38$82.4M
Exits27$118.9M

All 13F filers, Q1 2026 → Q2 2026: 15,120,133 shares bought and 15,112,052 shares sold, net +8,081 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 226 holders

Orbimed Advisors LLC 11.97% No change 15,518,492 $630.5M
Paradigm Biocapital Advisors LP 7.77% Add +38.7% 10,215,455 $415.1M
Ra Capital Management, L.P. 2.97% Reduce -19.5% 8,392,730 $341.0M
BlackRock, Inc. 0.00% Add +2.1% 6,606,336 $268.4M
Jupiter Topco LLC 0.10% — 6,075,331 $246.9M
FMR LLC 0.01% Add +439.7% 5,489,135 $223.0M
Novo Holdings A/S 12.62% No change 5,350,000 $217.4M
Driehaus Capital Management LLC 1.11% Add +5.6% 4,728,623 $192.1M
Perceptive Advisors LLC 2.77% Reduce -1.1% 4,373,974 $177.7M
Vanguard Capital Management LLC 0.00% Add +1.9% 3,860,670 $156.9M
Baker Bros. Advisors LP 0.76% Reduce -43.7% 3,701,719 $150.4M
Siren, L.L.C. 2.63% Reduce -28.1% 3,184,629 $129.4M
Cormorant Asset Management, LP 5.23% Reduce -23.0% 2,510,000 $102.0M
Geode Capital Management, LLC 0.00% Add +21.5% 2,174,051 $88.3M
Integral Health Asset Management, LLC 3.33% Add +25.0% 2,000,000 $81.3M
Braidwell LP 3.12% Reduce -14.9% 1,996,965 $81.1M
Morgan Stanley 0.00% Reduce -13.2% 1,948,597 $79.2M
State Street Corp. 0.00% Add +6.5% 1,827,927 $74.3M
Alliancebernstein L.P. 0.02% Add +23.0% 2,119,024 $66.7M
MPM Bioimpact LLC 4.02% Reduce -2.4% 1,620,780 $65.9M
Bank of America Corp. 0.00% Add +17.4% 1,558,260 $63.3M
Qube Research & Technologies Ltd 0.06% Add +51.6% 1,252,507 $50.9M
Dimensional Fund Advisors LP 0.01% Reduce -6.6% 1,139,726 $46.3M
American Century Companies Inc. 0.02% Reduce -1.8% 1,127,078 $45.8M
First Light Asset Management, LLC 2.70% Add +9.3% 1,095,171 $44.5M
Victory Capital Management Inc. 0.02% Add +14.4% 902,870 $36.7M
T. Rowe Price Associates Inc. 0.00% Add +1076.1% 816,518 $33.2M
Vanguard Portfolio Management LLC 0.00% Add +41.1% 786,456 $32.0M
Northern Trust Corp. 0.00% Add +16.4% 671,270 $27.3M
Aberdeen Group plc 0.04% Reduce -21.6% 647,926 $26.3M
Charles Schwab Investment Management Inc. 0.00% Add +4.1% 620,532 $25.2M
Tyro Capital Management LLC 5.59% New 612,965 $24.9M
Goldman Sachs Group Inc. 0.00% Reduce -4.8% 599,469 $24.4M
Parkman Healthcare Partners LLC 2.41% Add +78.7% 577,036 $23.4M
Artisan Partners Limited Partnership 0.04% Reduce -12.8% 574,925 $23.4M
Vanguard Fiduciary Trust Co. 0.00% Add +5.1% 548,285 $22.3M
Norges Bank 0.00% — 510,140 $20.7M
Opaleye Management Inc. 1.84% No change 500,000 $20.3M
Citadel Advisors 0.01% Add +9.5% 469,707 $19.1M
Adage Capital Partners Gp, L.L.C. 0.03% New 462,000 $18.8M
Soleus Capital Management, L.P. 0.63% Reduce -68.9% 450,889 $18.3M
Nuveen, LLC 0.00% Add +23.5% 414,706 $16.8M
Sofinnova Investments, Inc. 0.83% Reduce -1.4% 380,923 $15.5M
Healthcare of Ontario Pension Plan Trust Fund 0.02% Reduce -17.4% 334,014 $13.6M
Raymond James Financial Inc. 0.00% Add +1513.8% 317,565 $12.9M
Squadron Capital Management LLC 4.03% Reduce -17.1% 290,000 $11.8M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.02% Add +0.0% 283,333 $11.5M
Diadema Partners LP 4.18% New 272,214 $11.1M
Prudential Financial Inc. 0.01% Add +2358.5% 260,725 $10.6M
Kennedy Capital Management LLC 0.18% Reduce -2.9% 256,608 $10.4M
Schonfeld Strategic Advisors LLC 0.06% Add +157.6% 255,202 $10.4M
Deutsche Bank AG 0.00% Add +10.4% 244,995 $10.0M
DAFNA Capital Management LLC 1.76% Add +102.1% 226,819 $9.2M
Woodline Partners LP 0.03% No change 224,290 $9.1M
Bank of New York Mellon Corp 0.00% Add +10.3% 212,347 $8.6M
JPMorgan Chase & Co. 0.00% Add +37.7% 203,151 $8.5M
Peregrine Capital Management LLC 0.26% Reduce -4.8% 198,570 $8.1M
SEB Asset Management AB 0.03% Reduce -6.0% 194,063 $7.9M
Granahan Investment Management, LLC 0.28% Reduce -3.5% 193,778 $7.9M
Neuberger Berman Group LLC 0.01% Add +13.3% 191,195 $7.8M
Barclays PLC 0.00% Add +7.3% 190,205 $7.7M
D. E. Shaw & Co. 0.01% Add +80.3% 189,115 $7.7M
UBS Group AG 0.00% Reduce -86.7% 174,967 $7.1M
ADAR1 Capital Management, LLC 0.28% Add +58.1% 143,199 $5.8M
KVP Capital Advisors, LP 3.97% No change 133,000 $5.4M
Invesco Ltd. 0.00% Reduce -12.6% 120,932 $4.9M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +3.0% 118,209 $4.8M
Point72 Asset Management 0.01% New 117,262 $4.8M
Quantum Private Wealth, LLC 1.18% Reduce -2.8% 113,380 $4.6M
Alps Advisors Inc. 0.02% Add +24.6% 108,795 $4.4M
Moody Aldrich Partners LLC 0.77% Reduce -8.1% 104,952 $4.3M
Artia Global Partners LP 0.76% Add +50.8% 98,800 $4.0M
Swiss National Bank 0.00% Reduce -6.8% 96,800 $3.9M
Voya Investment Management LLC 0.00% Add +141.8% 94,671 $3.8M
HSBC Holdings PLC 0.00% New 91,638 $3.7M
HighVista Strategies LLC 0.84% Reduce -1.0% 90,996 $3.7M
Rhumbline Advisers 0.00% Add +8.0% 90,232 $3.7M
Ally Bridge Group (NY) LLC 4.36% Reduce -48.3% 83,300 $3.4M
Boothbay Fund Management, LLC 0.07% New 82,734 $3.4M
New York State Common Retirement Fund 0.00% Reduce -9.8% 80,197 $3.3M
Wells Fargo & Company 0.00% Add +212.5% 78,898 $3.2M
Russell Investments Group, Ltd. 0.00% Add +1082.4% 77,733 $3.2M
Jefferies Financial Group Inc. 0.03% New 71,389 $2.9M
California State Teachers Retirement System 0.00% Reduce -2.9% 71,306 $2.9M
Persistent Asset Partners Ltd 0.89% Add +590.8% 69,441 $2.8M
Nomura Asset Management International Inc. 0.00% Reduce -3.7% 64,918 $2.6M
DekaBank Deutsche Girozentrale 0.00% No change 80,000 $2.5M
Citigroup Inc. 0.00% Add +221.7% 59,563 $2.4M
Tudor Investment Corporation 0.01% Add +90.5% 56,934 $2.3M
State of Wisconsin Investment Board 0.00% Add +73.0% 56,910 $2.3M
HighMark Wealth Management LLC 0.72% No change 53,179 $2.2M
Two Sigma Investments, LP 0.00% Reduce -2.6% 49,548 $2.0M
Sei Investments Co. 0.00% Reduce -3.1% 47,543 $1.9M
Algert Global LLC 0.02% Add +45.3% 47,240 $1.9M
XTX Topco Ltd 0.02% Add +139.9% 45,832 $1.9M
Legal & General Group Plc 0.00% Add +5.1% 44,688 $1.8M
Gsa Capital Partners LLP 0.11% New 44,466 $1.8M
BNP Paribas Financial Markets 0.00% Add +82.3% 43,587 $1.8M
MetLife Investment Management, LLC 0.01% Add +9.8% 41,804 $1.7M
Manufacturers Life Insurance Company, The 0.00% Add +15.0% 40,757 $1.7M
Ensign Peak Advisors, Inc 0.00% New 40,379 $1.6M
Creative Planning 0.00% Add +25.4% 39,198 $1.6M
Knights of Columbus Asset Advisors LLC 0.08% Add +0.6% 38,641 $1.6M
Franklin Resources Inc. 0.00% Reduce -9.9% 37,605 $1.5M
Aquatic Capital Management LLC 0.05% New 36,918 $1.5M
VANGUARD ASSET MANAGEMENT, Ltd 0.00% No change 35,744 $1.5M
Vanguard Global Advisers, LLC 0.00% Add +20.4% 35,303 $1.4M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.2% 32,939 $1.3M
Handelsbanken Fonder AB 0.00% Reduce -1.9% 30,500 $1.2M
Jane Street Group, LLC 0.00% Reduce -15.9% 29,934 $1.2M
Verdad Advisers, LP 1.06% Add +108.7% 27,234 $1.1M
Brevan Howard Capital Management LP 0.02% New 26,566 $1.1M
Wellington Management Group LLP 0.00% Reduce -6.4% 25,659 $1.0M
Glenmede Trust Co. NA 0.00% Add +27.4% 24,484 $995K
Campbell & CO Investment Adviser LLC 0.05% New 23,829 $968K
Envestnet Asset Management Inc. 0.00% Add +44.2% 22,685 $922K
STRS Ohio 0.00% Add +205.8% 21,100 $857K
Police & Firemen's Retirement System of New Jersey 0.01% Add +11.8% 21,096 $857K
Quantinno Capital Management LP 0.00% Add +172.3% 20,299 $825K
LMR Partners LLP 0.01% No change 20,000 $813K
Longaeva Partners L.P. 0.02% Reduce -49.1% 18,790 $763K
AQR Capital Management 0.00% Add +116.1% 18,456 $750K
China Universal Asset Management Co., Ltd. 0.04% Reduce -27.8% 18,373 $746K
Odyssean, LLC 0.12% No change 17,867 $726K
State Board of Administration of Florida Retirement System 0.00% No change 16,870 $685K
Intech Investment Management LLC 0.01% Reduce -10.3% 16,578 $674K
Captrust Financial Advisors 0.00% New 16,288 $662K
AlphaCentric Advisors LLC 0.55% Add +1.4% 15,840 $644K
State of New Jersey Common Pension Fund D 0.00% Reduce -13.7% 15,608 $634K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +3.7% 15,288 $621K
SummitTX Capital, L.P. 0.02% New 14,738 $599K
Vanguard Investments Australia, Ltd. 0.00% No change 13,686 $556K
Guggenheim Capital LLC 0.00% Add +18.4% 13,649 $555K
Arizona State Retirement System 0.00% Reduce -8.4% 13,320 $541K
State of Wyoming 0.05% New 12,913 $525K
ProShare Advisors LLC 0.00% Reduce -11.6% 12,890 $524K
Corient Private Wealth LP 0.00% New 12,365 $502K
Advisory Services Network, LLC 0.01% Add +7985.4% 12,209 $496K
KLP Kapitalforvaltning As 0.00% No change 11,300 $459K
J. Goldman & Co LP 0.01% Reduce -83.4% 10,183 $414K
Verition Fund Management LLC 0.00% New 10,000 $406K
First Trust Advisors LP 0.00% Add +8.2% 9,877 $401K
Connecticut Capital Management Group, LLC 0.32% Reduce -0.1% 9,824 $399K
Virtus Investment Advisers, LLC 0.09% Reduce -18.6% 9,395 $382K
Private Advisor Group, LLC 0.00% New 9,341 $380K
Bridgefront Capital, LLC 0.10% Reduce -22.2% 9,184 $373K
Profund Advisors LLC 0.01% Add +5.5% 9,164 $372K
Lion Point Capital, LP 1.77% No change 9,100 $370K
Allianz Asset Management GmbH 0.00% New 9,100 $370K
Osaic Holdings, Inc. 0.00% Add +2.5% 8,694 $353K
Xponance LLC 0.00% New 7,027 $286K
VARCOV Co. 0.11% New 7,009 $285K
Orion Porfolio Solutions, LLC 0.00% Add +7.5% 6,930 $282K
Engineers Gate Manager LP 0.00% New 6,670 $271K
Ameritas Investment Partners, Inc. 0.01% Add +15.1% 6,491 $264K
Pictet Asset Management Holding SA 0.00% Reduce -17.6% 6,280 $255K
Marex Group Ltd 0.00% New 6,274 $255K
Marshall Wace, LLP 0.00% Reduce -99.1% 6,100 $248K
Rafferty Asset Management, LLC 0.00% New 6,035 $245K
Fox Run Management, L.L.C. 0.04% Reduce -24.6% 6,014 $244K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% New 5,900 $240K
Susquehanna International Group, LLP 0.00% Reduce -78.7% 5,692 $231K
Squarepoint Ops LLC 0.00% New 5,655 $230K
Teacher Retirement System of Texas 0.00% Reduce -17.1% 5,569 $226K
Axq Capital, LP 0.02% Reduce -41.8% 5,537 $225K
Principal Financial Group Inc. 0.00% New 5,470 $222K
Y-Intercept (Hong Kong) Ltd 0.00% New 5,466 $222K
PSP Research LLC 0.11% Reduce -23.1% 5,000 $203K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -14.0% 4,812 $196K
Group One Trading LLC 0.01% New 4,477 $182K
Royal Bank of Canada 0.00% Reduce -35.9% 3,762 $153K
US Bancorp \de 0.00% Add +13.9% 3,386 $138K
Public Employees Retirement Association of Colorado 0.00% No change 2,849 $116K
Tower Research Capital LLC (TRC) 0.00% Reduce -48.6% 2,812 $114K
GF Fund Management Co. LTD. 0.00% Reduce -4.5% 2,272 $92K
GAMMA Investing LLC 0.00% Reduce -8.0% 2,107 $86K
Acadian Asset Management LLC 0.00% Reduce -39.0% 1,669 $67K
KBC Group NV 0.00% No change 1,560 $63K
Parallel Advisors, LLC 0.00% Add +46.6% 1,513 $61K
BI Asset Management Fondsmaeglerselskab A/S 0.00% New 1,439 $58K
Eleva Capital SAS 0.02% No change 17,460 $55K
Nisa Investment Advisors, LLC 0.00% Reduce -27.4% 1,218 $49K
Centiva Capital, LP 0.00% Add +125.8% 1,217 $49K
Steward Partners Investment Advisory, LLC 0.00% Reduce -48.4% 1,214 $49K
Federated Hermes, Inc. 0.00% Reduce -98.0% 1,138 $46K
Kemnay Advisory Services Inc. 0.00% Add +9.7% 829 $34K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -19.6% 782 $32K
Farther Finance Advisors, LLC 0.00% Reduce -13.5% 558 $23K
Bessemer Group Inc. 0.00% Reduce -81.9% 426 $17K
Optiver Holding B.V. 0.00% Add +41.4% 369 $15K
Signaturefd, LLC 0.00% No change 363 $15K
Nykredit A/S 0.00% — 356 $14K
Rockefeller Capital Management L.P. 0.00% Reduce -55.7% 324 $13K
MassMutual Private Wealth & Trust, FSB 0.00% No change 294 $12K
SMA Capital LLC 0.00% New 252 $10K
Sterling Capital Management LLC 0.00% Reduce -42.7% 251 $10K
Los Angeles Capital Management LLC 0.00% Reduce -95.9% 230 $9K
Aster Capital Management (DIFC) Ltd 0.00% Reduce -31.9% 211 $9K
Caitong International Asset Management Co., Ltd 0.00% Reduce -95.1% 208 $8K
SBI Securities Co., Ltd. 0.00% No change 206 $8K
Fifth Third Bancorp 0.00% Add +484.9% 193 $8K
Larson Financial Group LLC 0.00% Add +2.3% 180 $7K
PNC Financial Services Group, Inc. 0.00% Add +2.3% 176 $7K
Allworth Financial LP 0.00% Add +109.5% 176 $7K
Smartleaf Asset Management LLC 0.00% No change 162 $7K
Fortitude Family Office, LLC 0.00% No change 160 $7K
Rothschild Investment LLC 0.00% Add +11.1% 150 $6K
Hurley Capital, LLC 0.00% New 149 $6K
Versant Capital Management, Inc 0.00% Add +26.3% 120 $5K
Bfsg, LLC 0.00% No change 100 $4K
Quarry LP 0.00% Reduce -98.8% 71 $3K
EverSource Wealth Advisors, LLC 0.00% Reduce -59.4% 71 $3K
Arax Advisory Partners 0.00% New 51 $2K
Parkside Financial Bank & Trust 0.00% No change 35 $1K
Covestor Ltd 0.00% Add +162.5% 21 $1K
Ares Financial Consulting, LLC 0.00% New 23 $934
Northwestern Mutual Wealth Management Co. 0.00% New 23 $934
Jones Financial Companies LLLP 0.00% New 22 $912
Bare Financial Services, Inc 0.00% No change 18 $731
Global Retirement Partners, LLC 0.00% — 17 $691
Bell Investment Advisors, Inc 0.00% New 15 $610
IFP Advisors, Inc 0.00% No change 4 $163
Essential Partners LLC 0.00% No change 3 $122
Clearstead Advisors, LLC 0.00% New 3 $122
GHP Investment Advisors, Inc. 0.00% No change 3 $122
Hughes Financial Services, LLC 0.00% Add +50.0% 3 $122

"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.