Krystal BiotechKRYS
13F holders, Q2 2025 (June 30)275holders −24
40new positions
63sold out
5famous investors
$137.49avg. 13F price*
At the end of Q2 2025, 275 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, down 24 from Q1 2025. 40 opened new positions and 63 sold out. The largest holders were FMR LLC ($595.9M), BlackRock, Inc. ($528.6M) and Vanguard Group Inc. ($388.0M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 40 | $77.2M |
| Exits | 63 | $192.4M |
All 13F filers, Q1 2025 → Q2 2025: 2,646,331 shares bought and 2,589,793 shares sold, net +56,538 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 275 holders
| FMR LLC | 0.03% | Add +0.3% | 4,334,761 | $595.9M |
| BlackRock, Inc. | 0.01% | Reduce -2.5% | 3,845,155 | $528.6M |
| Vanguard Group Inc. | 0.01% | Reduce -0.1% | 2,822,888 | $388.0M |
| Avoro Capital Advisors LLC | 6.40% | Reduce -2.6% | 2,660,000 | $365.6M |
| State Street Corp. | 0.01% | Add +10.5% | 1,355,346 | $186.3M |
| Capital World Investors | 0.02% | Reduce -1.3% | 942,249 | $129.5M |
| Soleus Capital Management, L.P. | 8.76% | Add +108.9% | 922,958 | $126.9M |
| Braidwell LP | 4.78% | Add +81.6% | 727,811 | $100.0M |
| Frazier Life Sciences Management, L.P. | 3.79% | No change | 688,460 | $94.6M |
| Redmile Group, LLC | 9.71% | Reduce -10.1% | 663,471 | $91.2M |
| Geode Capital Management, LLC | 0.01% | Add +1.2% | 619,547 | $85.2M |
| Hood River Capital Management LLC | 1.02% | Add +1.6% | 533,023 | $73.3M |
| Goldman Sachs Group Inc. | 0.01% | Add +127.0% | 530,361 | $72.9M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -5.3% | 505,889 | $69.5M |
| Norges Bank | 0.00% | Add +3.5% | 282,706 | $38.9M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -36.4% | 261,383 | $35.9M |
| Northern Trust Corp. | 0.00% | Reduce -3.3% | 251,408 | $34.6M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -1.7% | 246,180 | $33.8M |
| Morgan Stanley | 0.00% | Reduce -21.4% | 234,421 | $32.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -59.3% | 234,320 | $32.2M |
| First Trust Advisors LP | 0.02% | Add +571.3% | 222,370 | $30.6M |
| Nuveen, LLC | 0.01% | Reduce -19.7% | 188,019 | $25.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -5.1% | 160,517 | $22.1M |
| Woodline Partners LP | 0.11% | Reduce -32.2% | 150,616 | $20.7M |
| Segall Bryant & Hamill, LLC | 0.29% | Add +2.3% | 148,614 | $20.4M |
| Readystate Asset Management LP | 1.53% | New | 147,980 | $20.3M |
| Principal Financial Group Inc. | 0.01% | Add +11.5% | 140,883 | $19.4M |
| Pictet Asset Management Holding SA | 0.02% | Add +100.0% | 130,537 | $17.9M |
| Bank of America Corp. | 0.00% | Add +31.6% | 121,812 | $16.7M |
| TimesSquare Capital Management, LLC | 0.23% | Reduce -19.7% | 114,204 | $15.7M |
| Marshall Wace, LLP | 0.02% | Add +552.5% | 112,382 | $15.4M |
| S Squared Technology, LLC | 6.33% | Add +12.3% | 109,215 | $15.0M |
| Aberdeen Group plc | 0.03% | Add +190.9% | 108,518 | $14.9M |
| Logos Global Management LP | 1.84% | New | 100,000 | $13.7M |
| UBS Group AG | 0.00% | Add +19.9% | 97,240 | $13.4M |
| Barclays PLC | 0.01% | Add +106.4% | 92,871 | $12.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -9.6% | 91,153 | $12.5M |
| William Blair Investment Management, LLC | 0.03% | New | 91,099 | $12.5M |
| Renaissance Technologies | 0.02% | Add +701.8% | 89,800 | $12.3M |
| Public Sector Pension Investment Board | 0.05% | Add +8.0% | 86,688 | $11.9M |
| C WorldWide Group Holding A/S | 0.16% | No change | 85,809 | $11.8M |
| Victory Capital Management Inc. | 0.01% | Add +10.0% | 80,123 | $11.0M |
| Invesco Ltd. | 0.00% | Reduce -72.1% | 70,888 | $9.7M |
| Rhumbline Advisers | 0.01% | Add +3.0% | 70,753 | $9.7M |
| Raymond James Financial Inc. | 0.00% | Add +4.2% | 68,735 | $9.4M |
| Legal & General Group Plc | 0.00% | Add +2.8% | 68,393 | $9.4M |
| Handelsbanken Fonder AB | 0.03% | Reduce -10.1% | 66,800 | $9.2M |
| Decheng Capital LLC | 2.29% | Add +1.5% | 66,000 | $9.1M |
| Voya Investment Management LLC | 0.01% | Reduce -0.9% | 63,993 | $8.8M |
| Ameriprise Financial Inc. | 0.00% | Add +3.9% | 62,835 | $8.6M |
| Skandinaviska Enskilda Banken AB (publ) | 0.04% | No change | 59,978 | $8.2M |
| Alyeska Investment Group, L.P. | 0.03% | New | 53,934 | $7.4M |
| Citigroup Inc. | 0.01% | Reduce -28.6% | 52,533 | $7.2M |
| Federated Hermes, Inc. | 0.01% | Add +234.4% | 42,743 | $5.9M |
| Swiss National Bank | 0.00% | Reduce -1.0% | 41,400 | $5.7M |
| Corient Private Wealth LP | 0.01% | Reduce -3.8% | 40,538 | $5.6M |
| Palisades Investment Partners, LLC | 2.42% | Reduce -1.2% | 40,203 | $5.5M |
| Mutual of America Capital Management LLC | 0.06% | Add +5.3% | 38,357 | $5.3M |
| Kennedy Capital Management LLC | 0.13% | Reduce -8.1% | 38,146 | $5.2M |
| State of Wisconsin Investment Board | 0.01% | Add +49.2% | 36,089 | $5.0M |
| Rafferty Asset Management, LLC | 0.02% | Add +43.5% | 34,665 | $4.8M |
| Citadel Advisors | 0.00% | Add +35900.0% | 34,560 | $4.8M |
| Prudential Financial Inc. | 0.01% | Reduce -4.3% | 26,151 | $4.4M |
| Alliancebernstein L.P. | 0.00% | No change | 31,120 | $4.3M |
| Man Group plc | 0.01% | New | 30,481 | $4.2M |
| Susquehanna International Group, LLP | 0.01% | Reduce -10.6% | 30,252 | $4.2M |
| GW&K Investment Management, LLC | 0.04% | Reduce -11.5% | 30,175 | $4.1M |
| Los Angeles Capital Management LLC | 0.01% | Add +6.9% | 26,638 | $3.7M |
| Verition Fund Management LLC | 0.02% | Add +42.4% | 26,514 | $3.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -23.8% | 24,680 | $3.4M |
| New York State Common Retirement Fund | 0.00% | No change | 23,382 | $3.2M |
| EFG Asset Management (North America) Corp. | 0.44% | Add +31.7% | 22,878 | $3.1M |
| Biondo Investment Advisors, LLC | 0.38% | New | 21,240 | $2.9M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -15.3% | 20,847 | $2.9M |
| Synovus Financial Corp. | 0.03% | New | 20,643 | $2.8M |
| Atle Fund Management AB | 1.19% | Reduce -14.2% | 20,158 | $2.8M |
| California State Teachers Retirement System | 0.00% | No change | 20,126 | $2.8M |
| TD Asset Management Inc | 0.00% | Reduce -50.1% | 20,080 | $2.8M |
| Edgestream Partners, L.P. | 0.08% | New | 19,678 | $2.7M |
| Sei Investments Co. | 0.00% | Add +3.3% | 19,300 | $2.7M |
| Deutsche Bank AG | 0.00% | Reduce -12.0% | 19,135 | $2.6M |
| Thrivent Financial for Lutherans | 0.01% | Add +0.6% | 18,700 | $2.6M |
| Franklin Resources Inc. | 0.00% | Reduce -3.1% | 18,425 | $2.5M |
| Erste Asset Management GmbH | 0.02% | No change | 18,200 | $2.5M |
| Alps Advisors Inc. | 0.01% | Add +809.5% | 17,462 | $2.4M |
| Wells Fargo & Company | 0.00% | Reduce -3.4% | 16,547 | $2.3M |
| New York State Teachers Retirement System | 0.00% | Reduce -2.1% | 15,650 | $2.2M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 15,503 | $2.1M |
| Fiera Capital Corp | 0.01% | Reduce -0.9% | 15,511 | $2.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -3.8% | 15,283 | $2.1M |
| State of Alaska, Department of Revenue | 0.02% | Add +7.9% | 15,130 | $2.1M |
| Envestnet Asset Management Inc. | 0.00% | Add +21.9% | 15,116 | $2.1M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +45.2% | 15,033 | $2.1M |
| MetLife Investment Management, LLC | 0.01% | Add +1.5% | 14,746 | $2.0M |
| Fieldview Capital Management, LLC | 0.30% | Reduce -11.0% | 14,546 | $2.0M |
| Rhenman & Partners Asset Management AB | 0.22% | Reduce -28.2% | 12,750 | $1.8M |
| SG Americas Securities, LLC | 0.01% | Add +860.9% | 12,607 | $1.7M |
| Millennium Management | 0.00% | Reduce -79.2% | 12,562 | $1.7M |
| Illinois Municipal Retirement Fund | 0.02% | Reduce -3.5% | 12,311 | $1.7M |
| Evolutionary Tree Capital Management, LLC | 1.79% | Reduce -7.8% | 12,296 | $1.7M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.