Krystal BiotechKRYS
13F holders, Q1 2026 (March 31)368holders +34
65new positions
34sold out
9famous investors
$258.13avg. 13F price*
At the end of Q1 2026, 368 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 34 from Q4 2025. 65 opened new positions and 34 sold out. The largest holders were FMR LLC ($1.1B), BlackRock, Inc. ($1.0B) and Avoro Capital Advisors LLC ($746.3M). 9 famous investors held it, including Ray Dalio (0.1% of Bridgewater Associates's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 65 | $56.0M |
| Exits | 34 | $40.4M |
All 13F filers, Q4 2025 → Q1 2026: 1,508,601 shares bought and 1,377,135 shares sold, net +131,466 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 368 holders
| FMR LLC | 0.06% | Add +0.6% | 4,373,987 | $1.1B |
| BlackRock, Inc. | 0.02% | Add +0.1% | 3,940,456 | $1.0B |
| Avoro Capital Advisors LLC | 7.35% | No change | 2,888,888 | $746.3M |
| Vanguard Portfolio Management LLC | 0.02% | — | 1,456,727 | $376.3M |
| State Street Corp. | 0.01% | Reduce -2.1% | 1,314,434 | $339.5M |
| Vanguard Capital Management LLC | 0.01% | — | 1,165,324 | $301.0M |
| Soleus Capital Management, L.P. | 12.06% | Add +22.5% | 1,153,087 | $297.9M |
| Capital World Investors | 0.03% | Add +1.9% | 824,720 | $213.0M |
| Redmile Group, LLC | 11.52% | Reduce -0.6% | 673,505 | $174.0M |
| Geode Capital Management, LLC | 0.01% | Add +5.3% | 643,975 | $166.4M |
| Hood River Capital Management LLC | 1.60% | Add +1.0% | 619,586 | $160.1M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -8.5% | 485,074 | $125.3M |
| Bellevue Group AG | 2.96% | Add +17.4% | 481,785 | $124.5M |
| Frazier Life Sciences Management, L.P. | 3.21% | Reduce -1.5% | 481,307 | $124.3M |
| Dimensional Fund Advisors LP | 0.03% | Reduce -4.9% | 468,990 | $121.1M |
| William Blair Investment Management, LLC | 0.35% | Add +8.2% | 407,178 | $105.2M |
| First Trust Advisors LP | 0.06% | Add +42.9% | 350,521 | $90.5M |
| Janus Henderson Group PLC | 0.03% | Add +21.5% | 266,659 | $68.9M |
| Bank of America Corp. | 0.00% | Add +36.6% | 260,647 | $67.3M |
| Northern Trust Corp. | 0.01% | Add +2.0% | 252,463 | $65.2M |
| Invesco Ltd. | 0.01% | Add +318.9% | 251,373 | $64.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -0.3% | 241,986 | $62.5M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -26.8% | 214,949 | $55.5M |
| Morgan Stanley | 0.00% | Reduce -5.6% | 209,082 | $54.0M |
| Braidwell LP | 1.79% | Reduce -9.7% | 182,425 | $47.1M |
| Franklin Resources Inc. | 0.01% | Add +42.6% | 179,265 | $46.3M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 179,161 | $46.3M |
| Principal Financial Group Inc. | 0.02% | Reduce -1.8% | 162,070 | $41.9M |
| Raymond James Financial Inc. | 0.01% | Add +103.9% | 156,064 | $39.5M |
| Woodline Partners LP | 0.15% | No change | 150,616 | $38.9M |
| Bank of New York Mellon Corp | 0.01% | Reduce -1.3% | 149,307 | $38.6M |
| UBS Group AG | 0.01% | Reduce -10.1% | 143,525 | $37.1M |
| Nuveen, LLC | 0.01% | Reduce -24.2% | 143,368 | $37.0M |
| TimesSquare Capital Management, LLC | 0.49% | Add +15.3% | 112,342 | $29.0M |
| Pictet Asset Management Holding SA | 0.03% | Reduce -29.3% | 110,665 | $28.6M |
| Voya Investment Management LLC | 0.03% | Add +5.0% | 108,397 | $28.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -26.4% | 99,105 | $24.5M |
| BNP Paribas Financial Markets | 0.02% | Add +72.6% | 93,031 | $24.0M |
| Public Sector Pension Investment Board | 0.07% | Add +3.3% | 92,286 | $23.8M |
| Handelsbanken Fonder AB | 0.08% | Reduce -13.6% | 91,400 | $23.6M |
| S Squared Technology, LLC | 8.43% | Reduce -10.4% | 86,215 | $22.3M |
| Segall Bryant & Hamill, LLC | 0.29% | Reduce -4.5% | 79,497 | $20.5M |
| Biondo Investment Advisors, LLC | 2.39% | Add +5.8% | 72,045 | $18.6M |
| Orbimed Advisors LLC | 0.40% | Reduce -42.3% | 69,100 | $17.8M |
| Marshall Wace, LLP | 0.02% | Reduce -62.8% | 68,343 | $17.7M |
| Rhumbline Advisers | 0.01% | Add +2.5% | 68,099 | $17.6M |
| C WorldWide Group Holding A/S | 0.38% | Reduce -21.0% | 67,809 | $17.5M |
| Act Capital Management, LLC | 12.28% | Reduce -0.0% | 60,477 | $15.6M |
| Legal & General Group Plc | 0.00% | Reduce -6.8% | 59,050 | $15.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -4.8% | 49,837 | $12.9M |
| Sei Investments Co. | 0.01% | Add +44.1% | 46,570 | $12.0M |
| Bridgewater Associates | 0.05% | Add +363.0% | 46,367 | $12.0M |
| SEB Asset Management AB | 0.05% | — | 46,343 | $12.0M |
| Palisades Investment Partners, LLC | 4.60% | Add +6.2% | 45,405 | $11.7M |
| TD Asset Management Inc | 0.01% | Reduce -20.0% | 43,318 | $11.2M |
| Swiss National Bank | 0.01% | Add +0.2% | 43,000 | $11.1M |
| 1832 Asset Management L.P. | 0.01% | Add +142.1% | 42,600 | $11.0M |
| Victory Capital Management Inc. | 0.01% | Add +53.9% | 40,715 | $10.5M |
| Gilder Gagnon Howe & Co. LLC | 0.12% | New | 40,128 | $10.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +9.9% | 36,937 | $9.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -11.2% | 36,069 | $9.3M |
| Mutual of America Capital Management LLC | 0.11% | Reduce -3.8% | 35,859 | $9.3M |
| Federated Hermes, Inc. | 0.01% | Add +2.8% | 35,495 | $9.2M |
| Neuberger Berman Group LLC | 0.01% | Add +3102.7% | 33,084 | $8.5M |
| Castleark Management LLC | 0.27% | Add +8.1% | 31,630 | $8.2M |
| New York State Common Retirement Fund | 0.01% | No change | 31,342 | $8.1M |
| Citigroup Inc. | 0.01% | Add +4.1% | 31,172 | $8.1M |
| Alliancebernstein L.P. | 0.00% | Add +1.3% | 31,929 | $7.9M |
| Aberdeen Group plc | 0.01% | Reduce -23.4% | 30,155 | $7.8M |
| Prudential Financial Inc. | 0.01% | Add +9.7% | 29,638 | $7.7M |
| Fisher Asset Management | 0.00% | Add +633.9% | 27,784 | $7.2M |
| Atle Fund Management AB | 2.19% | Add +11.0% | 37,579 | $6.8M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -9.5% | 26,210 | $6.8M |
| California State Teachers Retirement System | 0.01% | Add +27.2% | 26,186 | $6.8M |
| Deutsche Bank AG | 0.00% | Add +10.6% | 24,831 | $6.4M |
| Granite Investment Partners, LLC | 0.39% | Reduce -5.7% | 24,284 | $6.3M |
| Fiera Capital Corp | 0.02% | Add +28.1% | 24,146 | $6.2M |
| Elmind Capital, LP | 1.61% | No change | 22,000 | $5.7M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -3.0% | 21,413 | $5.5M |
| State of Wisconsin Investment Board | 0.01% | Add +43.0% | 20,691 | $5.3M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 20,606 | $5.3M |
| Bessemer Group Inc. | 0.01% | Add +0.1% | 20,285 | $5.2M |
| Pinnacle Financial Partners, Inc. | 0.04% | Add +18.8% | 20,180 | $5.2M |
| EFG International AG | 0.11% | Reduce -14.9% | 20,049 | $5.2M |
| ADAR1 Capital Management, LLC | 0.31% | No change | 20,014 | $5.2M |
| Tetragon Partners GP Ltd | 1.00% | Add +66.5% | 19,668 | $5.1M |
| GW&K Investment Management, LLC | 0.04% | Reduce -1.7% | 19,245 | $5.0M |
| Lisanti Capital Growth, LLC | 1.21% | New | 18,515 | $4.8M |
| Zacks Investment Management | 0.04% | New | 17,919 | $4.6M |
| Campbell & CO Investment Adviser LLC | 0.26% | New | 17,795 | $4.6M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -27.1% | 17,687 | $4.6M |
| State of Alaska, Department of Revenue | 0.05% | Reduce -2.3% | 17,484 | $4.5M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -2.9% | 17,226 | $4.5M |
| Rhenman & Partners Asset Management AB | 0.53% | Reduce -33.3% | 16,675 | $4.3M |
| Informed Momentum Co LLC | 0.49% | Reduce -33.2% | 16,483 | $4.3M |
| Creative Planning | 0.00% | Add +14.8% | 15,937 | $4.1M |
| State Board of Administration of Florida Retirement System | 0.01% | No change | 15,756 | $4.1M |
| New York State Teachers Retirement System | 0.01% | Reduce -0.1% | 15,637 | $4.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +16.7% | 15,121 | $3.9M |
| Cim, LLC | 0.56% | New | 14,990 | $3.9M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.