Krystal BiotechKRYS
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 264 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, down 19 from Q3 2024. 28 opened new positions and 51 sold out. The largest holders were FMR LLC ($675.8M), BlackRock, Inc. ($631.9M) and Vanguard Group Inc. ($450.9M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 28 | $25.5M |
| Exits | 51 | $59.0M |
All 13F filers, Q3 2024 → Q4 2024: 1,065,195 shares bought and 1,604,382 shares sold, net −539,187 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 264 holders
| FMR LLC | 0.04% | Add +0.5% | 4,314,014 | $675.8M |
| BlackRock, Inc. | 0.01% | Add +1.0% | 4,033,872 | $631.9M |
| Vanguard Group Inc. | 0.01% | Add +1.0% | 2,878,451 | $450.9M |
| Avoro Capital Advisors LLC | 5.83% | Add +0.3% | 2,628,822 | $411.8M |
| State Street Corp. | 0.01% | Reduce -12.0% | 1,278,975 | $200.4M |
| Capital World Investors | 0.02% | Add +0.0% | 879,203 | $137.7M |
| Frazier Life Sciences Management, L.P. | 5.14% | Reduce -20.2% | 788,460 | $123.5M |
| Redmile Group, LLC | 8.22% | Reduce -7.0% | 753,175 | $118.0M |
| Geode Capital Management, LLC | 0.01% | Reduce -0.0% | 591,596 | $92.7M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -1.9% | 588,599 | $92.2M |
| Hood River Capital Management LLC | 1.19% | Add +2.1% | 512,726 | $80.3M |
| T. Rowe Price Associates Inc. | 0.01% | Add +16.3% | 509,459 | $79.8M |
| Soleus Capital Management, L.P. | 4.25% | Add +65.2% | 358,379 | $56.1M |
| Nuveen Asset Management, LLC | 0.01% | Reduce -2.5% | 304,115 | $47.6M |
| Jennison Associates LLC | 0.03% | Reduce -26.0% | 303,521 | $47.5M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -8.0% | 277,175 | $43.4M |
| Invesco Ltd. | 0.01% | Reduce -24.7% | 275,195 | $43.1M |
| Northern Trust Corp. | 0.01% | Add +9.9% | 262,263 | $41.1M |
| Morgan Stanley | 0.00% | Reduce -7.1% | 256,275 | $40.1M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +1.2% | 243,170 | $38.1M |
| Woodline Partners LP | 0.23% | Add +23.0% | 221,102 | $34.6M |
| Norges Bank | 0.00% | Reduce -10.1% | 219,528 | $34.4M |
| Lord, Abbett & Co. LLC | 0.11% | Reduce -24.1% | 215,628 | $33.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -6.5% | 210,202 | $32.9M |
| Braidwell LP | 1.40% | Add +18.9% | 200,500 | $31.4M |
| Franklin Resources Inc. | 0.01% | Reduce -24.5% | 184,027 | $28.8M |
| Baker Bros. Advisors LP | 0.29% | No change | 169,934 | $26.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.3% | 169,346 | $26.5M |
| TimesSquare Capital Management, LLC | 0.36% | Add +39.1% | 158,868 | $24.9M |
| JPMorgan Chase & Co. | 0.00% | Add +18.7% | 151,835 | $23.8M |
| Segall Bryant & Hamill, LLC | 0.32% | Reduce -5.0% | 149,309 | $23.4M |
| Principal Financial Group Inc. | 0.01% | Add +3.1% | 123,453 | $19.3M |
| Driehaus Capital Management LLC | 0.16% | Reduce -25.5% | 121,702 | $19.1M |
| Ameriprise Financial Inc. | 0.00% | Add +26.4% | 113,476 | $17.8M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -2.8% | 112,089 | $17.6M |
| C WorldWide Group Holding A/S | 0.20% | Reduce -22.1% | 105,809 | $16.6M |
| Raymond James Financial Inc. | 0.01% | — | 102,061 | $16.0M |
| UBS Group AG | 0.00% | Add +175.6% | 100,131 | $15.7M |
| Citigroup Inc. | 0.01% | Add +184.0% | 99,633 | $15.6M |
| Eventide Asset Management, LLC | 0.27% | No change | 95,781 | $15.0M |
| S Squared Technology, LLC | 6.20% | Add +26.6% | 95,215 | $14.9M |
| Skandinaviska Enskilda Banken AB (publ) | 0.06% | Reduce -29.4% | 89,047 | $14.2M |
| Handelsbanken Fonder AB | 0.05% | Reduce -9.9% | 85,300 | $13.4M |
| Victory Capital Management Inc. | 0.01% | Reduce -17.3% | 81,328 | $12.7M |
| Decheng Capital LLC | 2.58% | Add +7.0% | 76,772 | $12.0M |
| Bank of America Corp. | 0.00% | Reduce -27.6% | 75,799 | $11.9M |
| Voya Investment Management LLC | 0.01% | Add +5.8% | 74,701 | $11.7M |
| Legal & General Group Plc | 0.00% | Add +4.8% | 69,425 | $10.9M |
| Rhumbline Advisers | 0.01% | Reduce -1.7% | 69,136 | $10.8M |
| Public Sector Pension Investment Board | 0.04% | Add +17.4% | 63,010 | $9.9M |
| Aberdeen Group plc | 0.02% | Add +32.5% | 57,033 | $8.9M |
| Integral Health Asset Management, LLC | 0.76% | New | 55,000 | $8.6M |
| Janney Montgomery Scott LLC | 0.02% | Add +42.0% | 52,592 | $8.2M |
| Barclays PLC | 0.00% | Reduce -7.3% | 52,429 | $8.2M |
| Oberweis Asset Management Inc./ | 0.35% | No change | 46,800 | $7.3M |
| Prudential Financial Inc. | 0.01% | Add +8.6% | 41,193 | $6.8M |
| TD Asset Management Inc | 0.01% | Add +29.9% | 43,480 | $6.8M |
| Corient Private Wealth LP | 0.01% | Reduce -9.8% | 43,009 | $6.7M |
| Swiss National Bank | 0.00% | Add +8.4% | 42,400 | $6.6M |
| Palisades Investment Partners, LLC | 2.68% | Add +9.3% | 40,479 | $6.3M |
| Susquehanna International Group, LLP | 0.01% | Add +302.6% | 38,468 | $6.0M |
| Mutual of America Capital Management LLC | 0.06% | Reduce -0.1% | 36,518 | $5.7M |
| Jane Street Group, LLC | 0.01% | Add +97.2% | 35,855 | $5.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +12.8% | 35,206 | $5.5M |
| GW&K Investment Management, LLC | 0.05% | Reduce -3.0% | 34,930 | $5.5M |
| Alliancebernstein L.P. | 0.00% | Add +4.7% | 31,120 | $4.9M |
| Allspring Global Investments Holdings, LLC | 0.01% | Reduce -73.3% | 29,777 | $4.7M |
| Kennedy Capital Management LLC | 0.10% | Add +433.5% | 27,711 | $4.3M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -40.7% | 27,201 | $4.3M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -0.1% | 26,754 | $4.2M |
| Deutsche Bank AG | 0.00% | Add +62.5% | 25,361 | $4.0M |
| Verition Fund Management LLC | 0.02% | Add +55.6% | 24,902 | $3.9M |
| State of Wisconsin Investment Board | 0.01% | Add +6.2% | 24,502 | $3.8M |
| Edgestream Partners, L.P. | 0.16% | Reduce -26.2% | 23,810 | $3.7M |
| Rhenman & Partners Asset Management AB | 0.38% | Add +39.7% | 23,750 | $3.7M |
| Orbimed Advisors LLC | 0.08% | No change | 23,500 | $3.7M |
| New York State Common Retirement Fund | 0.00% | Reduce -9.6% | 23,382 | $3.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | — | 23,197 | $3.6M |
| First Trust Advisors LP | 0.00% | Reduce -41.2% | 23,169 | $3.6M |
| Caption Management, LLC | 0.14% | New | 22,339 | $3.5M |
| HRT Financial LP | 0.02% | New | 22,007 | $3.4M |
| Sei Investments Co. | 0.00% | Reduce -38.2% | 21,164 | $3.3M |
| California State Teachers Retirement System | 0.00% | Add +5.8% | 20,388 | $3.2M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -1.5% | 19,563 | $3.1M |
| Millennium Management | 0.00% | Reduce -60.2% | 18,956 | $3.0M |
| Erste Asset Management GmbH | 0.04% | No change | 18,200 | $2.9M |
| EFG Asset Management (North America) Corp. | 0.38% | Add +30.9% | 17,714 | $2.8M |
| Wells Fargo & Company | 0.00% | Add +21.3% | 16,928 | $2.7M |
| New York State Teachers Retirement System | 0.01% | No change | 15,879 | $2.5M |
| Fiera Capital Corp | 0.01% | Reduce -3.3% | 15,673 | $2.5M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 15,503 | $2.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Reduce -1.2% | 15,205 | $2.4M |
| MetLife Investment Management, LLC | 0.01% | Add +4.8% | 14,997 | $2.3M |
| State of Alaska, Department of Revenue | 0.03% | Reduce -0.0% | 14,423 | $2.3M |
| Illinois Municipal Retirement Fund | 0.03% | Add +11.9% | 14,146 | $2.2M |
| Hennion & Walsh Asset Management, Inc. | 0.10% | Reduce -1.7% | 13,678 | $2.1M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.2% | 13,225 | $2.1M |
| Federated Hermes, Inc. | 0.00% | Add +1.8% | 13,048 | $2.0M |
| Schroder Investment Management Group | 0.00% | No change | 12,607 | $2.0M |
| Louisiana State Employees Retirement System | 0.04% | No change | 12,200 | $1.9M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.