Krystal BiotechKRYS
13F holders, Q1 2025 (March 31)299holders +35
61new positions
27sold out
6famous investors
$180.30avg. 13F price*
At the end of Q1 2025, 299 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 35 from Q4 2024. 61 opened new positions and 27 sold out. The largest holders were FMR LLC ($779.0M), BlackRock, Inc. ($711.0M) and Vanguard Group Inc. ($509.4M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 61 | $98.6M |
| Exits | 27 | $61.1M |
All 13F filers, Q4 2024 → Q1 2025: 1,874,111 shares bought and 1,977,096 shares sold, net −102,985 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 299 holders
| FMR LLC | 0.05% | Add +0.2% | 4,320,832 | $779.0M |
| BlackRock, Inc. | 0.01% | Reduce -2.3% | 3,943,165 | $711.0M |
| Vanguard Group Inc. | 0.01% | Reduce -1.9% | 2,825,282 | $509.4M |
| Avoro Capital Advisors LLC | 7.69% | Add +3.9% | 2,731,000 | $492.4M |
| State Street Corp. | 0.01% | Reduce -4.1% | 1,226,707 | $221.2M |
| Capital World Investors | 0.03% | Add +8.6% | 954,468 | $172.1M |
| Redmile Group, LLC | 12.57% | Reduce -2.1% | 737,675 | $133.0M |
| Frazier Life Sciences Management, L.P. | 5.69% | Reduce -12.7% | 688,460 | $124.1M |
| Geode Capital Management, LLC | 0.01% | Add +3.5% | 612,353 | $110.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.03% | Add +173.8% | 575,506 | $103.8M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -9.3% | 533,919 | $96.3M |
| Hood River Capital Management LLC | 1.61% | Add +2.3% | 524,644 | $94.6M |
| Soleus Capital Management, L.P. | 6.25% | Add +23.3% | 441,758 | $79.6M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -19.4% | 410,861 | $74.1M |
| Braidwell LP | 3.77% | Add +99.9% | 400,744 | $72.3M |
| Morgan Stanley | 0.00% | Add +16.4% | 298,205 | $53.8M |
| Norges Bank | 0.01% | Add +24.4% | 273,209 | $49.3M |
| Northern Trust Corp. | 0.01% | Reduce -0.9% | 259,995 | $46.9M |
| Invesco Ltd. | 0.01% | Reduce -7.5% | 254,486 | $45.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.0% | 250,514 | $45.2M |
| Nuveen, LLC | 0.01% | — | 234,180 | $42.2M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -15.7% | 233,640 | $42.1M |
| Woodline Partners LP | 0.26% | Add +0.4% | 222,043 | $40.0M |
| T. Rowe Price Investment Management, Inc. | 0.02% | New | 185,550 | $33.5M |
| Bank of New York Mellon Corp | 0.01% | Reduce -0.1% | 169,179 | $30.5M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -29.9% | 151,225 | $27.3M |
| Segall Bryant & Hamill, LLC | 0.40% | Reduce -2.7% | 145,337 | $26.2M |
| TimesSquare Capital Management, LLC | 0.41% | Reduce -10.5% | 142,183 | $25.6M |
| 1832 Asset Management L.P. | 0.05% | New | 136,000 | $24.5M |
| Principal Financial Group Inc. | 0.01% | Add +2.3% | 126,337 | $22.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -33.6% | 100,774 | $18.2M |
| S Squared Technology, LLC | 8.97% | Add +2.1% | 97,215 | $17.5M |
| Eventide Asset Management, LLC | 0.34% | No change | 95,781 | $17.3M |
| Bank of America Corp. | 0.00% | Add +22.1% | 92,561 | $16.7M |
| C WorldWide Group Holding A/S | 0.19% | Reduce -18.9% | 85,809 | $15.5M |
| Squarepoint Ops LLC | 0.04% | Add +757.8% | 81,999 | $14.8M |
| UBS Group AG | 0.00% | Reduce -19.0% | 81,119 | $14.6M |
| Public Sector Pension Investment Board | 0.06% | Add +27.4% | 80,264 | $14.5M |
| Handelsbanken Fonder AB | 0.06% | Reduce -12.9% | 74,300 | $13.4M |
| Citigroup Inc. | 0.01% | Reduce -26.2% | 73,525 | $13.3M |
| Victory Capital Management Inc. | 0.01% | Reduce -10.5% | 72,815 | $13.1M |
| Rhumbline Advisers | 0.01% | Reduce -0.6% | 68,727 | $12.4M |
| Legal & General Group Plc | 0.00% | Reduce -4.2% | 66,509 | $12.0M |
| Raymond James Financial Inc. | 0.00% | Reduce -35.4% | 65,961 | $11.9M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -41.8% | 65,262 | $11.8M |
| Decheng Capital LLC | 3.29% | Reduce -15.3% | 65,000 | $11.7M |
| Voya Investment Management LLC | 0.02% | Reduce -13.5% | 64,601 | $11.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -46.7% | 60,508 | $10.9M |
| Millennium Management | 0.01% | Add +218.6% | 60,388 | $10.9M |
| Integral Health Asset Management, LLC | 1.20% | Add +9.1% | 60,000 | $10.8M |
| Skandinaviska Enskilda Banken AB (publ) | 0.05% | Reduce -32.6% | 59,978 | $10.8M |
| D. E. Shaw & Co. | 0.01% | Add +571.8% | 49,892 | $9.0M |
| Oberweis Asset Management Inc./ | 0.42% | No change | 46,800 | $8.4M |
| Janney Montgomery Scott LLC | 0.02% | Reduce -12.7% | 45,935 | $8.3M |
| Barclays PLC | 0.00% | Reduce -14.2% | 44,997 | $8.1M |
| Corient Private Wealth LP | 0.01% | Reduce -2.0% | 42,127 | $7.6M |
| Swiss National Bank | 0.01% | Reduce -1.4% | 41,800 | $7.5M |
| Kennedy Capital Management LLC | 0.18% | Add +49.8% | 41,518 | $7.5M |
| Palisades Investment Partners, LLC | 3.68% | Add +0.5% | 40,696 | $7.3M |
| TD Asset Management Inc | 0.01% | Reduce -7.4% | 40,268 | $7.3M |
| Russell Investments Group, Ltd. | 0.01% | Add +8390.1% | 37,781 | $6.8M |
| Aberdeen Group plc | 0.01% | Reduce -34.6% | 37,301 | $6.7M |
| Mutual of America Capital Management LLC | 0.08% | Reduce -0.2% | 36,431 | $6.6M |
| GW&K Investment Management, LLC | 0.06% | Reduce -2.4% | 34,100 | $6.1M |
| Susquehanna International Group, LLP | 0.01% | Reduce -12.1% | 33,829 | $6.1M |
| Jennison Associates LLC | 0.00% | Reduce -88.9% | 33,594 | $6.1M |
| First Trust Advisors LP | 0.01% | Add +43.0% | 33,125 | $6.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -8.1% | 32,366 | $5.8M |
| Beacon Harbor Wealth Advisors, Inc. | 1.35% | New | 32,235 | $5.8M |
| Alliancebernstein L.P. | 0.00% | No change | 31,120 | $5.6M |
| Lisanti Capital Growth, LLC | 1.63% | New | 30,410 | $5.5M |
| Prudential Financial Inc. | 0.01% | Reduce -33.7% | 27,311 | $4.9M |
| Castleark Management LLC | 0.16% | New | 26,120 | $4.7M |
| Los Angeles Capital Management LLC | 0.02% | Add +152.2% | 24,929 | $4.5M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -8.0% | 24,609 | $4.4M |
| State of Wisconsin Investment Board | 0.01% | Reduce -1.3% | 24,183 | $4.4M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -11.2% | 24,161 | $4.4M |
| Jane Street Group, LLC | 0.01% | Reduce -34.0% | 23,663 | $4.3M |
| Orbimed Advisors LLC | 0.10% | No change | 23,500 | $4.2M |
| Atle Fund Management AB | 1.87% | Add +155.3% | 23,491 | $4.2M |
| New York State Common Retirement Fund | 0.01% | No change | 23,382 | $4.2M |
| Deutsche Bank AG | 0.00% | Reduce -14.3% | 21,737 | $3.9M |
| California State Teachers Retirement System | 0.00% | Reduce -1.3% | 20,126 | $3.6M |
| Franklin Resources Inc. | 0.00% | Reduce -89.7% | 19,013 | $3.4M |
| Sei Investments Co. | 0.00% | Reduce -11.7% | 18,691 | $3.4M |
| Verition Fund Management LLC | 0.02% | Reduce -25.2% | 18,625 | $3.4M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +144.9% | 18,624 | $3.4M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -5.0% | 18,590 | $3.4M |
| Erste Asset Management GmbH | 0.04% | No change | 18,200 | $3.3M |
| Rhenman & Partners Asset Management AB | 0.37% | Reduce -25.3% | 17,750 | $3.2M |
| EFG Asset Management (North America) Corp. | 0.52% | Reduce -1.9% | 17,371 | $3.1M |
| Marshall Wace, LLP | 0.00% | Add +66.7% | 17,224 | $3.1M |
| Wells Fargo & Company | 0.00% | Add +1.2% | 17,135 | $3.1M |
| Fieldview Capital Management, LLC | 0.42% | New | 16,342 | $2.9M |
| New York State Teachers Retirement System | 0.01% | Add +0.6% | 15,979 | $2.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +4.5% | 15,893 | $2.9M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 15,503 | $2.8M |
| Fiera Capital Corp | 0.01% | Reduce -0.2% | 15,645 | $2.8M |
| MetLife Investment Management, LLC | 0.01% | Reduce -3.1% | 14,524 | $2.6M |
| State of Alaska, Department of Revenue | 0.03% | Reduce -2.8% | 14,024 | $2.5M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.