Krystal BiotechKRYS
13F holders, Q3 2025 (September 30)284holders +9
43new positions
30sold out
6famous investors
$176.29avg. 13F price*
At the end of Q3 2025, 284 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 9 from Q2 2025. 43 opened new positions and 30 sold out. The largest holders were FMR LLC ($766.4M), BlackRock, Inc. ($676.8M) and Vanguard Group Inc. ($492.9M). 6 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ray Dalio (0.0% of Bridgewater Associates's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 43 | $34.8M |
| Exits | 30 | $47.8M |
All 13F filers, Q2 2025 → Q3 2025: 2,096,277 shares bought and 1,448,289 shares sold, net +647,988 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 284 holders
| FMR LLC | 0.04% | Add +0.1% | 4,341,447 | $766.4M |
| BlackRock, Inc. | 0.01% | Reduce -0.3% | 3,834,128 | $676.8M |
| Vanguard Group Inc. | 0.01% | Reduce -1.1% | 2,792,208 | $492.9M |
| Avoro Capital Advisors LLC | 6.34% | Add +4.4% | 2,777,777 | $490.4M |
| State Street Corp. | 0.01% | Add +3.0% | 1,395,967 | $246.4M |
| Soleus Capital Management, L.P. | 9.61% | Add +10.4% | 1,018,831 | $179.9M |
| Capital World Investors | 0.02% | Reduce -14.1% | 809,240 | $142.9M |
| Frazier Life Sciences Management, L.P. | 3.65% | No change | 688,460 | $121.5M |
| Redmile Group, LLC | 11.36% | Reduce -0.3% | 661,388 | $116.8M |
| Citadel Advisors | 0.09% | Add +1743.1% | 636,988 | $112.4M |
| Geode Capital Management, LLC | 0.01% | Reduce -1.3% | 611,244 | $107.9M |
| Hood River Capital Management LLC | 1.27% | Add +13.9% | 606,946 | $107.1M |
| Dimensional Fund Advisors LP | 0.02% | Add +5.5% | 533,964 | $94.3M |
| Braidwell LP | 3.72% | Reduce -28.5% | 520,401 | $91.9M |
| T. Rowe Price Associates Inc. | 0.01% | Add +78.7% | 467,058 | $82.5M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -34.3% | 348,250 | $61.5M |
| First Trust Advisors LP | 0.03% | Add +11.7% | 248,392 | $43.8M |
| Northern Trust Corp. | 0.01% | Reduce -1.3% | 248,165 | $43.8M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -1.4% | 242,863 | $42.9M |
| Morgan Stanley | 0.00% | Add +0.1% | 234,578 | $41.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -13.5% | 202,589 | $35.8M |
| Nuveen, LLC | 0.01% | Add +5.0% | 197,378 | $34.8M |
| Pictet Asset Management Holding SA | 0.03% | Add +50.8% | 196,904 | $34.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.1% | 155,553 | $27.5M |
| Woodline Partners LP | 0.13% | No change | 150,616 | $26.6M |
| William Blair Investment Management, LLC | 0.07% | Add +63.9% | 149,302 | $26.4M |
| Millennium Management | 0.02% | Add +1083.8% | 148,713 | $26.3M |
| JPMorgan Chase & Co. | 0.00% | Add +60.6% | 146,354 | $25.8M |
| Principal Financial Group Inc. | 0.01% | Add +1.4% | 142,843 | $25.2M |
| Bank of America Corp. | 0.00% | Add +13.3% | 137,995 | $24.4M |
| UBS Group AG | 0.00% | Add +33.9% | 130,173 | $23.0M |
| Marshall Wace, LLP | 0.03% | Add +14.8% | 128,960 | $22.8M |
| TimesSquare Capital Management, LLC | 0.30% | Add +3.8% | 118,514 | $20.9M |
| S Squared Technology, LLC | 7.33% | No change | 109,215 | $19.3M |
| Orbimed Advisors LLC | 0.44% | Add +1016.8% | 102,745 | $18.1M |
| Public Sector Pension Investment Board | 0.07% | Add +15.8% | 100,431 | $17.7M |
| Voya Investment Management LLC | 0.02% | Add +46.8% | 93,908 | $16.6M |
| C WorldWide Group Holding A/S | 0.23% | No change | 85,809 | $15.1M |
| Segall Bryant & Hamill, LLC | 0.20% | Reduce -42.6% | 85,263 | $15.1M |
| Barclays PLC | 0.01% | Reduce -18.3% | 75,896 | $13.4M |
| Rhumbline Advisers | 0.01% | Reduce -0.3% | 70,552 | $12.5M |
| Readystate Asset Management LP | 1.21% | Reduce -52.5% | 70,349 | $12.4M |
| Invesco Ltd. | 0.00% | Reduce -5.7% | 66,880 | $11.8M |
| Handelsbanken Fonder AB | 0.04% | No change | 66,800 | $11.8M |
| Legal & General Group Plc | 0.00% | Reduce -3.8% | 65,815 | $11.6M |
| Raymond James Financial Inc. | 0.00% | Reduce -6.4% | 64,363 | $11.4M |
| Skandinaviska Enskilda Banken AB (publ) | 0.04% | No change | 59,978 | $10.6M |
| Aberdeen Group plc | 0.02% | Reduce -45.3% | 59,372 | $10.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -11.2% | 55,792 | $9.8M |
| Victory Capital Management Inc. | 0.01% | Reduce -31.6% | 54,816 | $9.7M |
| Biondo Investment Advisors, LLC | 1.15% | Add +144.3% | 51,885 | $9.2M |
| TD Asset Management Inc | 0.01% | Add +124.5% | 45,080 | $8.0M |
| Swiss National Bank | 0.00% | Add +1.4% | 42,000 | $7.4M |
| Palisades Investment Partners, LLC | 2.87% | Add +3.0% | 41,389 | $7.3M |
| Kennedy Capital Management LLC | 0.15% | Add +3.0% | 39,291 | $6.9M |
| Corient Private Wealth LP | 0.01% | Reduce -3.5% | 39,130 | $6.9M |
| Mutual of America Capital Management LLC | 0.07% | Reduce -1.1% | 37,934 | $6.7M |
| Perceptive Advisors LLC | 0.18% | New | 35,000 | $6.2M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -0.1% | 34,640 | $6.1M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +39.6% | 34,455 | $6.1M |
| Decheng Capital LLC | 0.99% | Reduce -51.1% | 32,300 | $5.7M |
| Verition Fund Management LLC | 0.03% | Add +18.2% | 31,333 | $5.5M |
| Alliancebernstein L.P. | 0.00% | Reduce -3.9% | 29,920 | $5.3M |
| State of Wisconsin Investment Board | 0.01% | Reduce -18.7% | 29,340 | $5.2M |
| EFG Asset Management (North America) Corp. | 0.62% | Add +18.4% | 27,095 | $4.8M |
| New York State Common Retirement Fund | 0.01% | Add +15.4% | 26,994 | $4.8M |
| Russell Investments Group, Ltd. | 0.01% | Add +156.3% | 26,549 | $4.7M |
| Prudential Financial Inc. | 0.01% | Reduce -2.5% | 25,496 | $4.5M |
| Ikarian Capital, LLC | 0.87% | New | 24,421 | $4.3M |
| Federated Hermes, Inc. | 0.01% | Reduce -43.9% | 23,981 | $4.2M |
| Sei Investments Co. | 0.00% | Add +21.2% | 23,393 | $4.1M |
| CANADA LIFE ASSURANCE Co | 0.01% | Add +2.6% | 21,398 | $3.8M |
| Deutsche Bank AG | 0.00% | Add +11.7% | 21,379 | $3.8M |
| California State Teachers Retirement System | 0.00% | Add +3.8% | 20,882 | $3.7M |
| Synovus Financial Corp. | 0.04% | Reduce -0.6% | 20,516 | $3.6M |
| AQR Capital Management | 0.00% | Add +68.2% | 20,133 | $3.6M |
| Franklin Resources Inc. | 0.00% | Add +7.7% | 19,850 | $3.5M |
| Wells Fargo & Company | 0.00% | Add +18.8% | 19,653 | $3.5M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -0.6% | 18,584 | $3.3M |
| ADAR1 Capital Management, LLC | 0.33% | New | 18,523 | $3.3M |
| Erste Asset Management GmbH | 0.03% | No change | 18,200 | $3.2M |
| New York State Teachers Retirement System | 0.01% | Reduce -0.6% | 15,550 | $2.7M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 15,503 | $2.7M |
| Fiera Capital Corp | 0.01% | Reduce -2.9% | 15,063 | $2.7M |
| Fieldview Capital Management, LLC | 0.42% | Add +1.1% | 14,705 | $2.6M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -2.9% | 14,599 | $2.6M |
| MetLife Investment Management, LLC | 0.01% | Reduce -2.1% | 14,430 | $2.5M |
| State of Alaska, Department of Revenue | 0.03% | Reduce -5.7% | 14,274 | $2.5M |
| Illinois Municipal Retirement Fund | 0.03% | Add +15.7% | 14,245 | $2.5M |
| Bridge City Capital, LLC | 0.67% | New | 14,154 | $2.5M |
| Alps Advisors Inc. | 0.01% | Reduce -23.4% | 13,367 | $2.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -13.0% | 13,290 | $2.3M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -13.3% | 13,108 | $2.3M |
| Evolutionary Tree Capital Management, LLC | 2.40% | Add +1.3% | 12,461 | $2.2M |
| Privium Fund Management B.V. | 0.39% | Add +30.6% | 12,170 | $2.1M |
| Torray Investment Partners LLC | 0.29% | Add +2.8% | 11,901 | $2.1M |
| Louisiana State Employees Retirement System | 0.04% | Reduce -0.8% | 11,800 | $2.1M |
| Rhenman & Partners Asset Management AB | 0.23% | Reduce -7.8% | 11,750 | $2.1M |
| Creative Planning | 0.00% | Add +38.9% | 11,609 | $2.0M |
| State of Tennessee, Department of Treasury | 0.01% | Add +1.5% | 11,118 | $2.0M |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.