Krystal BiotechKRYS
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 299 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 35 from Q4 2024. 61 opened new positions and 27 sold out. The largest holders were FMR LLC ($779.0M), BlackRock, Inc. ($711.0M) and Vanguard Group Inc. ($509.4M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Krystal Biotech Inc.
- CUSIP
- 501147102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 61 | $98.6M |
| Exits | 27 | $61.1M |
All 13F filers, Q4 2024 → Q1 2025: 1,874,111 shares bought and 1,977,096 shares sold, net −102,985 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 299 holders
| FMR LLC | 0.05% | Add +0.2% | 4,320,832 | $779.0M |
| BlackRock, Inc. | 0.01% | Reduce -2.3% | 3,943,165 | $711.0M |
| Vanguard Group Inc. | 0.01% | Reduce -1.9% | 2,825,282 | $509.4M |
| Avoro Capital Advisors LLC | 7.69% | Add +3.9% | 2,731,000 | $492.4M |
| State Street Corp. | 0.01% | Reduce -4.1% | 1,226,707 | $221.2M |
| Capital World Investors | 0.03% | Add +8.6% | 954,468 | $172.1M |
| Redmile Group, LLC | 12.57% | Reduce -2.1% | 737,675 | $133.0M |
| Frazier Life Sciences Management, L.P. | 5.69% | Reduce -12.7% | 688,460 | $124.1M |
| Geode Capital Management, LLC | 0.01% | Add +3.5% | 612,353 | $110.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.03% | Add +173.8% | 575,506 | $103.8M |
| Dimensional Fund Advisors LP | 0.02% | Reduce -9.3% | 533,919 | $96.3M |
| Hood River Capital Management LLC | 1.61% | Add +2.3% | 524,644 | $94.6M |
| Soleus Capital Management, L.P. | 6.25% | Add +23.3% | 441,758 | $79.6M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -19.4% | 410,861 | $74.1M |
| Braidwell LP | 3.77% | Add +99.9% | 400,744 | $72.3M |
| Morgan Stanley | 0.00% | Add +16.4% | 298,205 | $53.8M |
| Norges Bank | 0.01% | Add +24.4% | 273,209 | $49.3M |
| Northern Trust Corp. | 0.01% | Reduce -0.9% | 259,995 | $46.9M |
| Invesco Ltd. | 0.01% | Reduce -7.5% | 254,486 | $45.9M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.0% | 250,514 | $45.2M |
| Nuveen, LLC | 0.01% | — | 234,180 | $42.2M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -15.7% | 233,640 | $42.1M |
| Woodline Partners LP | 0.26% | Add +0.4% | 222,043 | $40.0M |
| T. Rowe Price Investment Management, Inc. | 0.02% | New | 185,550 | $33.5M |
| Bank of New York Mellon Corp | 0.01% | Reduce -0.1% | 169,179 | $30.5M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -29.9% | 151,225 | $27.3M |
| Segall Bryant & Hamill, LLC | 0.40% | Reduce -2.7% | 145,337 | $26.2M |
| TimesSquare Capital Management, LLC | 0.41% | Reduce -10.5% | 142,183 | $25.6M |
| 1832 Asset Management L.P. | 0.05% | New | 136,000 | $24.5M |
| Principal Financial Group Inc. | 0.01% | Add +2.3% | 126,337 | $22.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -33.6% | 100,774 | $18.2M |
| S Squared Technology, LLC | 8.97% | Add +2.1% | 97,215 | $17.5M |
| Eventide Asset Management, LLC | 0.34% | No change | 95,781 | $17.3M |
| Bank of America Corp. | 0.00% | Add +22.1% | 92,561 | $16.7M |
| C WorldWide Group Holding A/S | 0.19% | Reduce -18.9% | 85,809 | $15.5M |
| Squarepoint Ops LLC | 0.04% | Add +757.8% | 81,999 | $14.8M |
| UBS Group AG | 0.00% | Reduce -19.0% | 81,119 | $14.6M |
| Public Sector Pension Investment Board | 0.06% | Add +27.4% | 80,264 | $14.5M |
| Handelsbanken Fonder AB | 0.06% | Reduce -12.9% | 74,300 | $13.4M |
| Citigroup Inc. | 0.01% | Reduce -26.2% | 73,525 | $13.3M |
| Victory Capital Management Inc. | 0.01% | Reduce -10.5% | 72,815 | $13.1M |
| Rhumbline Advisers | 0.01% | Reduce -0.6% | 68,727 | $12.4M |
| Legal & General Group Plc | 0.00% | Reduce -4.2% | 66,509 | $12.0M |
| Raymond James Financial Inc. | 0.00% | Reduce -35.4% | 65,961 | $11.9M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -41.8% | 65,262 | $11.8M |
| Decheng Capital LLC | 3.29% | Reduce -15.3% | 65,000 | $11.7M |
| Voya Investment Management LLC | 0.02% | Reduce -13.5% | 64,601 | $11.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -46.7% | 60,508 | $10.9M |
| Millennium Management | 0.01% | Add +218.6% | 60,388 | $10.9M |
| Integral Health Asset Management, LLC | 1.20% | Add +9.1% | 60,000 | $10.8M |
| Skandinaviska Enskilda Banken AB (publ) | 0.05% | Reduce -32.6% | 59,978 | $10.8M |
| D. E. Shaw & Co. | 0.01% | Add +571.8% | 49,892 | $9.0M |
| Oberweis Asset Management Inc./ | 0.42% | No change | 46,800 | $8.4M |
| Janney Montgomery Scott LLC | 0.02% | Reduce -12.7% | 45,935 | $8.3M |
| Barclays PLC | 0.00% | Reduce -14.2% | 44,997 | $8.1M |
| Corient Private Wealth LP | 0.01% | Reduce -2.0% | 42,127 | $7.6M |
| Swiss National Bank | 0.01% | Reduce -1.4% | 41,800 | $7.5M |
| Kennedy Capital Management LLC | 0.18% | Add +49.8% | 41,518 | $7.5M |
| Palisades Investment Partners, LLC | 3.68% | Add +0.5% | 40,696 | $7.3M |
| TD Asset Management Inc | 0.01% | Reduce -7.4% | 40,268 | $7.3M |
| Russell Investments Group, Ltd. | 0.01% | Add +8390.1% | 37,781 | $6.8M |
| Aberdeen Group plc | 0.01% | Reduce -34.6% | 37,301 | $6.7M |
| Mutual of America Capital Management LLC | 0.08% | Reduce -0.2% | 36,431 | $6.6M |
| GW&K Investment Management, LLC | 0.06% | Reduce -2.4% | 34,100 | $6.1M |
| Susquehanna International Group, LLP | 0.01% | Reduce -12.1% | 33,829 | $6.1M |
| Jennison Associates LLC | 0.00% | Reduce -88.9% | 33,594 | $6.1M |
| First Trust Advisors LP | 0.01% | Add +43.0% | 33,125 | $6.0M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -8.1% | 32,366 | $5.8M |
| Beacon Harbor Wealth Advisors, Inc. | 1.35% | New | 32,235 | $5.8M |
| Alliancebernstein L.P. | 0.00% | No change | 31,120 | $5.6M |
| Lisanti Capital Growth, LLC | 1.63% | New | 30,410 | $5.5M |
| Prudential Financial Inc. | 0.01% | Reduce -33.7% | 27,311 | $4.9M |
| Castleark Management LLC | 0.16% | New | 26,120 | $4.7M |
| Los Angeles Capital Management LLC | 0.02% | Add +152.2% | 24,929 | $4.5M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -8.0% | 24,609 | $4.4M |
| State of Wisconsin Investment Board | 0.01% | Reduce -1.3% | 24,183 | $4.4M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -11.2% | 24,161 | $4.4M |
| Jane Street Group, LLC | 0.01% | Reduce -34.0% | 23,663 | $4.3M |
| Orbimed Advisors LLC | 0.10% | No change | 23,500 | $4.2M |
| Atle Fund Management AB | 1.87% | Add +155.3% | 23,491 | $4.2M |
| New York State Common Retirement Fund | 0.01% | No change | 23,382 | $4.2M |
| Deutsche Bank AG | 0.00% | Reduce -14.3% | 21,737 | $3.9M |
| California State Teachers Retirement System | 0.00% | Reduce -1.3% | 20,126 | $3.6M |
| Franklin Resources Inc. | 0.00% | Reduce -89.7% | 19,013 | $3.4M |
| Sei Investments Co. | 0.00% | Reduce -11.7% | 18,691 | $3.4M |
| Verition Fund Management LLC | 0.02% | Reduce -25.2% | 18,625 | $3.4M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +144.9% | 18,624 | $3.4M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -5.0% | 18,590 | $3.4M |
| Erste Asset Management GmbH | 0.04% | No change | 18,200 | $3.3M |
| Rhenman & Partners Asset Management AB | 0.37% | Reduce -25.3% | 17,750 | $3.2M |
| EFG Asset Management (North America) Corp. | 0.52% | Reduce -1.9% | 17,371 | $3.1M |
| Marshall Wace, LLP | 0.00% | Add +66.7% | 17,224 | $3.1M |
| Wells Fargo & Company | 0.00% | Add +1.2% | 17,135 | $3.1M |
| Fieldview Capital Management, LLC | 0.42% | New | 16,342 | $2.9M |
| New York State Teachers Retirement System | 0.01% | Add +0.6% | 15,979 | $2.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +4.5% | 15,893 | $2.9M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 15,503 | $2.8M |
| Fiera Capital Corp | 0.01% | Reduce -0.2% | 15,645 | $2.8M |
| MetLife Investment Management, LLC | 0.01% | Reduce -3.1% | 14,524 | $2.6M |
| State of Alaska, Department of Revenue | 0.03% | Reduce -2.8% | 14,024 | $2.5M |
| Evolutionary Tree Capital Management, LLC | 2.80% | Add +24.7% | 13,343 | $2.4M |
| Schroder Investment Management Group | 0.00% | Add +3.5% | 13,048 | $2.4M |
| Trexquant Investment LP | 0.03% | New | 13,122 | $2.4M |
| Corebridge Financial, Inc. | 0.01% | Reduce -1.9% | 12,970 | $2.3M |
| Federated Hermes, Inc. | 0.01% | Reduce -2.0% | 12,781 | $2.3M |
| Illinois Municipal Retirement Fund | 0.03% | Reduce -9.8% | 12,762 | $2.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -45.0% | 12,753 | $2.3M |
| Envestnet Asset Management Inc. | 0.00% | Add +6.6% | 12,399 | $2.2M |
| AQR Capital Management | 0.00% | Add +29.9% | 12,131 | $2.2M |
| Creative Planning | 0.00% | Add +123.9% | 12,086 | $2.2M |
| Intech Investment Management LLC | 0.02% | Add +11.4% | 12,078 | $2.2M |
| Louisiana State Employees Retirement System | 0.04% | Reduce -2.5% | 11,900 | $2.1M |
| Redwood Investments, LLC | 0.76% | Reduce -0.7% | 11,267 | $2.0M |
| Renaissance Technologies | 0.00% | Add +2.8% | 11,200 | $2.0M |
| State of Tennessee, Department of Treasury | 0.01% | Reduce -1.2% | 11,162 | $2.0M |
| Wellington Management Group LLP | 0.00% | Reduce -9.4% | 10,599 | $1.9M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -12.3% | 10,351 | $1.9M |
| Janus Henderson Group PLC | 0.00% | No change | 10,071 | $1.9M |
| Hennion & Walsh Asset Management, Inc. | 0.08% | Reduce -25.4% | 10,205 | $1.8M |
| ExodusPoint Capital Management, LP | 0.02% | Add +2.0% | 9,952 | $1.8M |
| Yousif Capital Management, LLC | 0.02% | Reduce -2.1% | 9,570 | $1.7M |
| Dark Forest Capital Management LP | 0.08% | New | 9,437 | $1.7M |
| Blair William & Co. | 0.01% | Add +26.7% | 9,433 | $1.7M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 9,010 | $1.6M |
| Comerica Bank | 0.01% | Reduce -2.1% | 8,701 | $1.6M |
| Perigon Wealth Management, LLC | 0.04% | Add +2.4% | 8,491 | $1.5M |
| Pathstone Holdings, LLC | 0.01% | Add +90.7% | 8,109 | $1.5M |
| Jackson Creek Investment Advisors LLC | 0.46% | Reduce -0.1% | 8,048 | $1.5M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | — | 7,800 | $1.4M |
| Privium Fund Management B.V. | 0.35% | Reduce -18.8% | 7,510 | $1.4M |
| Maryland State Retirement & Pension System | 0.03% | Reduce -13.8% | 7,351 | $1.3M |
| Commonwealth Equity Services, LLC | 0.00% | Add +50.1% | 7,303 | $1.3M |
| WINTON GROUP Ltd | 0.08% | Add +10.8% | 7,274 | $1.3M |
| Quantum Private Wealth, LLC | 0.49% | No change | 7,205 | $1.3M |
| Amalgamated Bank | 0.01% | Reduce -3.2% | 7,200 | $1.3M |
| ProShare Advisors LLC | 0.00% | Reduce -19.2% | 7,151 | $1.3M |
| STRS Ohio | 0.01% | Reduce -5.5% | 6,900 | $1.2M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 6,569 | $1.2M |
| Nebula Research & Development LLC | 0.10% | Add +133.0% | 6,220 | $1.1M |
| Arizona State Retirement System | 0.01% | Reduce -1.1% | 6,171 | $1.1M |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.01% | Add +12.1% | 6,057 | $1.1M |
| Profund Advisors LLC | 0.05% | Reduce -5.7% | 5,963 | $1.1M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 5,807 | $1.0M |
| Teacher Retirement System of Texas | 0.00% | Reduce -9.1% | 5,805 | $1.0M |
| Oregon Public Employees Retirement Fund | 0.02% | Reduce -2.9% | 5,802 | $1.0M |
| China Universal Asset Management Co., Ltd. | 0.10% | Reduce -5.3% | 5,778 | $1.0M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -5.2% | 5,742 | $1.0M |
| Cibc World Markets Corp. | 0.01% | Add +137.1% | 5,504 | $992K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +2.6% | 5,420 | $977K |
| Legato Capital Management LLC | 0.13% | New | 5,190 | $936K |
| Martingale Asset Management L P | 0.02% | No change | 5,136 | $926K |
| Main Management ETF Advisors, LLC | 0.04% | Add +41.8% | 5,047 | $910K |
| Allspring Global Investments Holdings, LLC | 0.00% | Reduce -82.6% | 5,180 | $904K |
| Gotham Asset Management | 0.01% | New | 4,804 | $866K |
| Summit Global Investments | 0.06% | Add +36.4% | 4,711 | $849K |
| HRT Financial LP | 0.01% | Reduce -78.7% | 4,680 | $843K |
| Prime Capital Investment Advisors, LLC | 0.01% | New | 4,504 | $812K |
| BNP Paribas Financial Markets | 0.00% | Reduce -43.0% | 4,437 | $800K |
| Pier 88 Investment Partners LLC | 0.96% | Add +18.1% | 4,430 | $799K |
| Bank of Montreal | 0.00% | Add +32.9% | 4,418 | $797K |
| Eschler Asset Management LLP | 1.97% | New | 4,403 | $794K |
| Bryce Point Capital, LLC | 0.59% | New | 4,286 | $790K |
| Regal Investment Advisors LLC | 0.06% | New | 4,307 | $777K |
| KLP Kapitalforvaltning As | 0.00% | No change | 4,300 | $775K |
| Jefferies Financial Group Inc. | 0.01% | New | 4,200 | $757K |
| Guggenheim Capital LLC | 0.01% | Reduce -14.6% | 4,153 | $749K |
| Cynosure Group, LLC | 0.10% | Add +7.5% | 3,902 | $704K |
| Quadrant Capital Group LLC | 0.03% | Add +2373.3% | 3,883 | $700K |
| Fred Alger Management, LLC | 0.00% | New | 3,728 | $672K |
| Allianz Asset Management GmbH | 0.00% | Reduce -9.4% | 3,715 | $670K |
| M&T Bank Corp | 0.00% | New | 3,700 | $667K |
| Mariner, LLC | 0.00% | Add +7.8% | 3,637 | $656K |
| Roman Butler Fullerton & Co. | 0.25% | New | 3,867 | $654K |
| Advantage Alpha Capital Partners LP | 0.16% | New | 3,569 | $643K |
| Jain Global LLC | 0.01% | Reduce -28.3% | 3,442 | $621K |
| Aviva PLC | 0.00% | New | 3,256 | $587K |
| Jump Financial, LLC | 0.01% | New | 2,983 | $538K |
| HSBC Holdings PLC | 0.00% | Reduce -36.4% | 2,875 | $508K |
| Vident Advisory, LLC | 0.01% | Add +11.8% | 2,787 | $502K |
| Aster Capital Management (DIFC) Ltd | 0.09% | New | 2,776 | $498K |
| Scientech Research LLC | 0.13% | New | 2,737 | $493K |
| Vontobel Holding Ltd. | 0.00% | Reduce -9.5% | 2,700 | $487K |
| Confluence Wealth Services, Inc. | 0.03% | No change | 2,920 | $484K |
| Bellevue Group AG | 0.01% | Reduce -47.5% | 2,650 | $478K |
| EP Wealth Advisors, LLC | 0.00% | New | 2,621 | $473K |
| Certuity, LLC | 0.05% | Add +89.4% | 2,585 | $466K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 2,582 | $466K |
| Ameritas Investment Partners, Inc. | 0.02% | Reduce -3.3% | 2,509 | $452K |
| Crossmark Global Holdings, Inc. | 0.01% | Add +2.7% | 2,370 | $427K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 2,363 | $426K |
| Fox Run Management, L.L.C. | 0.07% | Add +8.9% | 2,354 | $424K |
| Entropy Technologies, LP | 0.04% | Reduce -34.3% | 2,300 | $415K |
| E Fund Management Co., Ltd. | 0.02% | Add +16.8% | 2,258 | $407K |
| Susquehanna Fundamental Investments, LLC | 0.01% | New | 2,242 | $404K |
| Graham Capital Management, L.P. | 0.02% | Add +4.7% | 2,179 | $393K |
| PNC Financial Services Group, Inc. | 0.00% | Add +27.4% | 2,141 | $386K |
| Ballentine Partners, LLC | 0.01% | Reduce -0.4% | 2,136 | $385K |
| Cetera Investment Advisers | 0.00% | Reduce -4.0% | 2,089 | $377K |
| Virtus Investment Advisers, LLC | 0.10% | New | 2,068 | $373K |
| OmniStar Financial Group, Inc. | 0.29% | New | 2,026 | $365K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 2,000 | $361K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +39.0% | 1,946 | $351K |
| Alps Advisors Inc. | 0.00% | New | 1,920 | $346K |
| Xponance LLC | 0.00% | Add +4.9% | 1,873 | $338K |
| SIH Partners, LLLP | 0.03% | New | 1,815 | $327K |
| DNB Asset Management AS | 0.00% | Add +15.7% | 1,779 | $321K |
| Parallel Advisors, LLC | 0.01% | Reduce -46.5% | 1,731 | $312K |
| United Services Automobile Association | 0.01% | New | 1,661 | $305K |
| Argent Trust Co | 0.01% | Reduce -10.9% | 1,692 | $305K |
| AlphaQuest LLC | 0.03% | Reduce -44.9% | 1,663 | $300K |
| LPL Financial LLC | 0.00% | Reduce -43.6% | 1,660 | $299K |
| Royal Bank of Canada | 0.00% | Add +145.2% | 1,628 | $294K |
| O'shaughnessy Asset Management, LLC | 0.00% | New | 1,538 | $277K |
| Mackenzie Financial Corp. | 0.00% | No change | 1,532 | $276K |
| Sound View Wealth Advisors Group, LLC | 0.02% | Add +6.7% | 1,515 | $273K |
| Syon Capital LLC | 0.02% | New | 1,506 | $272K |
| Covestor Ltd | 0.18% | Add +111.4% | 1,497 | $270K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Add +9.1% | 1,492 | $269K |
| Cwm, LLC | 0.00% | Reduce -81.7% | 1,476 | $266K |
| Mindset Wealth Management, LLC | 0.10% | New | 1,450 | $261K |
| Ethic Inc. | 0.01% | New | 1,431 | $250K |
| Transcend Capital Advisors, LLC | 0.02% | Add +0.1% | 1,383 | $249K |
| Two Sigma Securities, LLC | 0.04% | New | 1,361 | $245K |
| Evergreen Capital Management LLC | 0.01% | New | 1,348 | $243K |
| Shaker Investments LLC | 0.12% | New | 1,329 | $240K |
| SG Americas Securities, LLC | 0.00% | New | 1,312 | $237K |
| Canada Pension Plan Investment Board | 0.00% | New | 1,300 | $234K |
| Oppenheimer Asset Management Inc. | 0.00% | New | 1,269 | $229K |
| Avanza Fonder AB | 0.01% | Add +66.0% | 1,260 | $228K |
| Elevation Point Wealth Partners, LLC | 0.02% | New | 1,239 | $223K |
| Empowered Funds, LLC | 0.00% | New | 1,211 | $218K |
| Hilltop Holdings Inc. | 0.01% | New | 1,196 | $216K |
| Magnetar Financial LLC | 0.00% | New | 1,175 | $212K |
| Orion Porfolio Solutions, LLC | 0.00% | New | 1,160 | $209K |
| Orion Portfolio Solutions, LLC | 0.00% | New | 1,160 | $209K |
| Headlands Technologies LLC | 0.02% | Reduce -38.2% | 1,010 | $182K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.6% | 964 | $177K |
| KBC Group NV | 0.00% | No change | 939 | $169K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -8.7% | 920 | $166K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 736 | $133K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -89.6% | 730 | $132K |
| Pacer Advisors, Inc. | 0.00% | Reduce -49.4% | 708 | $128K |
| GAMMA Investing LLC | 0.01% | Add +179.3% | 673 | $121K |
| US Bancorp \de | 0.00% | Reduce -37.8% | 639 | $115K |
| Coldstream Capital Management Inc. | 0.00% | New | 556 | $100K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 408 | $74K |
| Lazard Asset Management LLC | 0.00% | Reduce -15.1% | 404 | $72K |
| Smartleaf Asset Management LLC | 0.01% | Add +128.3% | 315 | $58K |
| Osaic Holdings, Inc. | 0.00% | Reduce -9.2% | 278 | $50K |
| Caldwell Trust Co | 0.00% | No change | 250 | $45K |
| Wilmington Savings Fund Society, FSB | 0.00% | Add +3.2% | 225 | $41K |
| Huntington National Bank | 0.00% | Reduce -63.2% | 213 | $38K |
| Fifth Third Bancorp | 0.00% | Add +159.1% | 171 | $31K |
| Twin Tree Management, LP | 0.00% | New | 161 | $29K |
| Key Financial Inc | 0.01% | No change | 151 | $27K |
| Brooklyn Investment Group | 0.01% | Add +291.7% | 141 | $25K |
| MAI Capital Management | 0.00% | No change | 134 | $24K |
| Signaturefd, LLC | 0.00% | Add +21.5% | 130 | $23K |
| Citadel Advisors | 0.00% | Reduce -99.1% | 96 | $17K |
| Daiwa Securities Group Inc. | 0.00% | No change | 95 | $17K |
| First Horizon Advisors, Inc. | 0.00% | New | 78 | $14K |
| UMB Bank, n.a. | 0.00% | Add +108.6% | 73 | $13K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -40.3% | 71 | $13K |
| Bessemer Group Inc. | 0.00% | Add +27.8% | 69 | $12K |
| Rise Advisors, LLC | 0.01% | New | 66 | $12K |
| Quent Capital, LLC | 0.00% | New | 59 | $11K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +139.1% | 55 | $10K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +100.0% | 52 | $9K |
| Lindbrook Capital, LLC | 0.00% | Reduce -12.1% | 51 | $9K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 50 | $9K |
| Rothschild Investment LLC | 0.00% | Add +170.6% | 46 | $8K |
| Versant Capital Management, Inc | 0.00% | Reduce -30.2% | 37 | $7K |
| NewEdge Advisors, LLC | 0.00% | No change | 34 | $6K |
| Sterling Capital Management LLC | 0.00% | Add +4.0% | 26 | $5K |
| Allworth Financial LP | 0.00% | Add +333.3% | 26 | $4K |
| Clearstead Advisors, LLC | 0.00% | No change | 24 | $4K |
| Farther Finance Advisors, LLC | 0.00% | No change | 23 | $4K |
| Parkside Financial Bank & Trust | 0.00% | Add +600.0% | 21 | $4K |
| Trust Co. of Vermont | 0.00% | No change | 20 | $4K |
| Bell Investment Advisors, Inc | 0.00% | Reduce -32.1% | 19 | $3K |
| Farmers & Merchants Investments Inc. | 0.00% | No change | 15 | $3K |
| Lanark Financial, Inc. | 0.00% | — | 15 | $2K |
| Bare Financial Services, Inc | 0.00% | New | 11 | $2K |
| Highline Wealth Partners LLC | 0.00% | New | 10 | $2K |
| Sound Income Strategies, LLC | 0.00% | No change | 10 | $2K |
| Blue Trust, Inc. | 0.00% | Add +200.0% | 9 | $2K |
| Wolff Wiese Magana LLC | 0.00% | No change | 8 | $1K |
| Geneos Wealth Management Inc. | 0.00% | New | 8 | $1K |
| Principal Securities, Inc. | 0.00% | No change | 7 | $1K |
| Rakuten Securities, Inc. | 0.00% | Reduce -75.0% | 5 | $902 |
| Private Wealth Management Group, LLC | 0.00% | No change | 5 | $902 |
| Stephens Consulting, LLC | 0.00% | New | 5 | $902 |
| Glen Eagle Advisors, LLC | 0.00% | No change | 5 | $902 |
| Kestra Investment Management, LLC | 0.00% | New | 5 | $902 |
| Cornerstone Planning Group LLC | 0.00% | New | 4 | $663 |
| JFS Wealth Advisors, LLC | 0.00% | No change | 2 | $361 |
| Abound Wealth Management | 0.00% | Reduce -50.0% | 1 | $181 |
| TFC Financial Management, Inc. | 0.00% | New | 1 | $181 |
| Hantz Financial Services, Inc. | 0.00% | New | 2 | $0 |
"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.