Prelude TherapeuticsPRLD
13F holders, Q1 2025 (March 31)58holders −3
4new positions
7sold out
4famous investors
$0.88avg. 13F price*
At the end of Q1 2025, 58 institutions reported holding Prelude Therapeutics Inc. (PRLD) in their 13F filings, down 3 from Q4 2024. 4 opened new positions and 7 sold out. The largest holders were Orbimed Advisors LLC ($8.4M), Baker Bros. Advisors LP ($7.8M) and Nuveen, LLC ($3.6M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Prelude Therapeutics Inc.
- CUSIP
- 74065P101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 4 | $56K |
| Exits | 7 | $2.1M |
All 13F filers, Q4 2024 → Q1 2025: 680,621 shares bought and 2,486,633 shares sold, net −1,806,012 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 58 holders
| Orbimed Advisors LLC | 0.20% | No change | 10,909,256 | $8.4M |
| Baker Bros. Advisors LP | 0.09% | No change | 10,123,824 | $7.8M |
| Nuveen, LLC | 0.00% | — | 187,613 | $3.6M |
| Boxer Capital Management, LLC | 0.49% | Add +23.4% | 2,108,014 | $1.6M |
| BlackRock, Inc. | 0.00% | Reduce -2.1% | 1,047,725 | $805K |
| Vanguard Group Inc. | 0.00% | Reduce -0.1% | 1,009,204 | $775K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -5.2% | 976,147 | $750K |
| Renaissance Technologies | 0.00% | Add +3.5% | 656,700 | $504K |
| Acadian Asset Management LLC | 0.00% | Add +9.1% | 529,327 | $405K |
| Geode Capital Management, LLC | 0.00% | Add +0.7% | 404,955 | $311K |
| Morgan Stanley | 0.00% | Reduce -17.1% | 302,779 | $233K |
| State Street Corp. | 0.00% | Reduce -2.5% | 286,046 | $220K |
| Two Sigma Advisers, LP | 0.00% | Reduce -13.2% | 260,400 | $200K |
| Two Sigma Investments, LP | 0.00% | Reduce -20.8% | 183,667 | $141K |
| TD Asset Management Inc | 0.00% | No change | 160,652 | $123K |
| Goldman Sachs Group Inc. | 0.00% | Add +4.6% | 155,215 | $119K |
| Millennium Management | 0.00% | Reduce -68.3% | 146,770 | $113K |
| Northern Trust Corp. | 0.00% | Add +40.2% | 116,907 | $90K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.7% | 114,050 | $88K |
| UBS Group AG | 0.00% | Add +42.7% | 96,156 | $74K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -20.3% | 88,500 | $68K |
| Deutsche Bank AG | 0.00% | Reduce -34.9% | 80,723 | $62K |
| Susquehanna International Group, LLP | 0.00% | Add +7.0% | 77,870 | $60K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -1.1% | 69,252 | $53K |
| Marex Group Ltd | 0.00% | New | 56,270 | $43K |
| Simplex Trading, LLC | 0.00% | Add +122.4% | 41,846 | $32K |
| Cerity Partners LLC | 0.00% | Add +5.1% | 34,565 | $27K |
| AQR Capital Management | 0.00% | Add +170.7% | 33,823 | $26K |
| Bank of New York Mellon Corp | 0.00% | No change | 28,613 | $22K |
| XTX Topco Ltd | 0.00% | Reduce -35.6% | 24,700 | $19K |
| JPMorgan Chase & Co. | 0.00% | Reduce -61.1% | 23,780 | $18K |
| Barclays PLC | 0.00% | Reduce -22.3% | 23,145 | $18K |
| HSBC Holdings PLC | 0.00% | Reduce -0.1% | 20,630 | $18K |
| FMR LLC | 0.00% | Add +138.0% | 20,238 | $16K |
| BNP Paribas Financial Markets | 0.00% | Reduce -4.4% | 19,668 | $15K |
| SG Americas Securities, LLC | 0.00% | New | 17,251 | $13K |
| Rhumbline Advisers | 0.00% | Reduce -90.7% | 15,499 | $12K |
| Bank of America Corp. | 0.00% | Reduce -25.2% | 15,446 | $12K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +30.9% | 13,586 | $10K |
| Citigroup Inc. | 0.00% | Reduce -9.0% | 9,300 | $7K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 7,912 | $6K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.1% | 7,887 | $6K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 6,458 | $5K |
| Cwm, LLC | 0.00% | Add +76.2% | 3,346 | $3K |
| New York State Common Retirement Fund | 0.00% | No change | 3,622 | $3K |
| SBI Securities Co., Ltd. | 0.00% | No change | 2,741 | $2K |
| Royal Bank of Canada | 0.00% | Reduce -10.1% | 3,344 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1762.5% | 1,192 | $915 |
| Legal & General Group Plc | 0.00% | No change | 962 | $739 |
| California State Teachers Retirement System | 0.00% | No change | 955 | $733 |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 819 | $629 |
| Group One Trading LLC | 0.00% | No change | 500 | $384 |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -21.3% | 400 | $307 |
| Sterling Capital Management LLC | 0.00% | Add +440.5% | 227 | $174 |
| Citadel Advisors | 0.00% | Reduce -99.7% | 34 | $26 |
| True Wealth Design, LLC | 0.00% | New | 10 | $8 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 9 | $7 |
| Amalgamated Bank | 0.00% | No change | 334 | $0 |
"% of holder's portfolio" is PRLD's weight in each manager's 13F, not the share of Prelude Therapeutics Inc. the manager owns.