Prelude TherapeuticsPRLD
13F holders, Q4 2024 (December 31)61holders −9
5new positions
15sold out
4famous investors
$1.28avg. 13F price*
At the end of Q4 2024, 61 institutions reported holding Prelude Therapeutics Inc. (PRLD) in their 13F filings, down 9 from Q3 2024. 5 opened new positions and 15 sold out. The largest holders were Orbimed Advisors LLC ($13.9M), Baker Bros. Advisors LP ($12.9M) and Boxer Capital Management, LLC ($2.2M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Prelude Therapeutics Inc.
- CUSIP
- 74065P101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 5 | $151K |
| Exits | 15 | $12.5M |
All 13F filers, Q3 2024 → Q4 2024: 2,747,864 shares bought and 6,339,237 shares sold, net −3,591,373 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 61 holders
| Orbimed Advisors LLC | 0.29% | No change | 10,909,256 | $13.9M |
| Baker Bros. Advisors LP | 0.14% | No change | 10,123,824 | $12.9M |
| Boxer Capital Management, LLC | 0.19% | — | 1,708,187 | $2.2M |
| BlackRock, Inc. | 0.00% | Add +1.1% | 1,069,773 | $1.4M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -6.2% | 1,029,199 | $1.3M |
| Vanguard Group Inc. | 0.00% | Reduce -1.1% | 1,010,392 | $1.3M |
| Jacobs Levy Equity Management, Inc. | 0.00% | Add +280.9% | 666,574 | $850K |
| Renaissance Technologies | 0.00% | Add +222.2% | 634,500 | $809K |
| Massachusetts Financial Services Co. | 0.00% | Reduce -10.0% | 494,497 | $630K |
| Acadian Asset Management LLC | 0.00% | Add +554.7% | 485,381 | $617K |
| Millennium Management | 0.00% | Add +188.2% | 462,555 | $590K |
| Geode Capital Management, LLC | 0.00% | Add +2.7% | 402,336 | $513K |
| Marshall Wace, LLP | 0.00% | Add +9.2% | 392,155 | $498K |
| Morgan Stanley | 0.00% | Add +12.8% | 365,159 | $466K |
| Two Sigma Advisers, LP | 0.00% | Add +526.3% | 300,000 | $383K |
| State Street Corp. | 0.00% | Add +2.6% | 293,396 | $374K |
| Two Sigma Investments, LP | 0.00% | Add +307.2% | 231,839 | $296K |
| Rhumbline Advisers | 0.00% | Add +1289.8% | 166,830 | $213K |
| TD Asset Management Inc | 0.00% | No change | 160,652 | $205K |
| Goldman Sachs Group Inc. | 0.00% | Add +55.9% | 148,326 | $189K |
| Deutsche Bank AG | 0.00% | Add +747.6% | 123,899 | $159K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -12.0% | 117,200 | $149K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -37.0% | 111,000 | $142K |
| Northern Trust Corp. | 0.00% | Reduce -21.6% | 83,387 | $106K |
| Susquehanna International Group, LLP | 0.00% | New | 72,799 | $93K |
| Manufacturers Life Insurance Company, The | 0.00% | No change | 70,045 | $89K |
| UBS Group AG | 0.00% | Add +860.5% | 67,390 | $86K |
| Exchange Traded Concepts, LLC | 0.00% | No change | 64,409 | $82K |
| JPMorgan Chase & Co. | 0.00% | Add +925.0% | 61,149 | $78K |
| Cerity Partners LLC | 0.00% | Add +0.0% | 32,877 | $68K |
| XTX Topco Ltd | 0.00% | Reduce -20.5% | 38,339 | $49K |
| Barclays PLC | 0.00% | Add +9.6% | 29,773 | $38K |
| Bank of New York Mellon Corp | 0.00% | No change | 28,613 | $36K |
| Bank of America Corp. | 0.00% | Reduce -17.2% | 20,654 | $26K |
| BNP Paribas Financial Markets | 0.00% | New | 20,572 | $26K |
| HSBC Holdings PLC | 0.00% | Reduce -0.6% | 20,640 | $26K |
| Simplex Trading, LLC | 0.00% | Add +101.6% | 18,814 | $23K |
| Nuveen Asset Management, LLC | 0.00% | No change | 16,797 | $21K |
| AQR Capital Management | 0.00% | New | 12,493 | $16K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 11,925 | $15K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -62.2% | 10,981 | $14K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +95.7% | 10,376 | $13K |
| Citadel Advisors | 0.00% | Reduce -32.4% | 10,297 | $13K |
| Citigroup Inc. | 0.00% | Add +5.8% | 10,215 | $13K |
| FMR LLC | 0.00% | Add +11.6% | 8,502 | $11K |
| Wells Fargo & Company | 0.00% | Add +27.8% | 7,737 | $10K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.2% | 7,575 | $10K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 6,554 | $8K |
| New York State Common Retirement Fund | 0.00% | No change | 3,622 | $5K |
| Royal Bank of Canada | 0.00% | Add +30.3% | 3,721 | $4K |
| SBI Securities Co., Ltd. | 0.00% | — | 2,741 | $3K |
| Cwm, LLC | 0.00% | Add +18890.0% | 1,899 | $2K |
| Legal & General Group Plc | 0.00% | No change | 962 | $1K |
| California State Teachers Retirement System | 0.00% | No change | 955 | $1K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 819 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | New | 508 | $648 |
| Group One Trading LLC | 0.00% | No change | 500 | $638 |
| PNC Financial Services Group, Inc. | 0.00% | No change | 64 | $82 |
| HighMark Wealth Management LLC | 0.00% | No change | 50 | $64 |
| Sterling Capital Management LLC | 0.00% | No change | 42 | $54 |
| Amalgamated Bank | 0.00% | No change | 334 | $0 |
"% of holder's portfolio" is PRLD's weight in each manager's 13F, not the share of Prelude Therapeutics Inc. the manager owns.