Prelude TherapeuticsPRLD

13F holders, Q3 2024 (September 30)
70holders +9
15new positions
7sold out
3famous investors
$2.07avg. 13F price*

At the end of Q3 2024, 70 institutions reported holding Prelude Therapeutics Inc. (PRLD) in their 13F filings, up 9 from Q2 2024. 15 opened new positions and 7 sold out. The largest holders were Orbimed Advisors LLC ($22.6M), Baker Bros. Advisors LP ($21.0M) and Deerfield Management Company, L.P. ($7.8M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Prelude Therapeutics Inc.
CUSIP
74065P101
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 58Q1 2024Q2 2024: 61Q2 2024Q3 2024: 70Q3 2024Q4 2024: 61Q4 2024Q1 2025: 58Q1 2025Q2 2025: 50Q2 2025Q3 2025: 47Q3 2025Q4 2025: 48Q4 2025Q1 2026: 55Q1 2026Q2 2026: 75Q2 2026

Total Exit/New Position Q2 2024 → Q3 2024

InstitutionsTotal Value
New Positions15$5.8M
Exits7$1.6M

All 13F filers, Q2 2024 → Q3 2024: 3,590,224 shares bought and 1,742,491 shares sold, net +1,847,733 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 70 holders

Orbimed Advisors LLC 0.41% No change 10,909,256 $22.6M
Baker Bros. Advisors LP 0.22% No change 10,123,824 $21.0M
Deerfield Management Company, L.P. 0.13% Reduce -8.9% 3,766,120 $7.8M
Boxer Capital, LLC 0.17% Reduce -33.5% 1,708,187 $3.5M
T. Rowe Price Associates Inc. 0.00% Add +23.1% 1,097,599 $2.3M
BlackRock, Inc. 0.00% — 1,058,316 $2.2M
Vanguard Group Inc. 0.00% Add +1.1% 1,021,770 $2.1M
ExodusPoint Capital Management, LP 0.02% New 921,621 $1.9M
Avidity Partners Management LP 0.09% New 890,000 $1.8M
Massachusetts Financial Services Co. 0.00% Add +5.2% 549,530 $1.1M
Geode Capital Management, LLC 0.00% Add +8.2% 391,716 $811K
Marshall Wace, LLP 0.00% New 359,137 $743K
Morgan Stanley 0.00% Add +12.6% 323,689 $670K
State Street Corp. 0.00% Add +35.1% 286,046 $592K
T. Rowe Price Investment Management, Inc. 0.00% New 281,583 $583K
Renaissance Technologies 0.00% Reduce -4.7% 196,900 $408K
Bridgeway Capital Management, LLC 0.01% Add +42.5% 176,100 $365K
Jacobs Levy Equity Management, Inc. 0.00% Add +885.2% 174,979 $362K
TD Asset Management Inc 0.00% No change 160,652 $341K
Millennium Management 0.00% New 160,524 $332K
Charles Schwab Investment Management Inc. 0.00% Add +4.1% 133,249 $276K
Northern Trust Corp. 0.00% Reduce -14.7% 106,377 $220K
Goldman Sachs Group Inc. 0.00% Add +27.0% 95,161 $197K
Walleye Capital LLC 0.00% Add +446.2% 83,175 $172K
Acadian Asset Management LLC 0.00% Add +235.3% 74,143 $152K
Manufacturers Life Insurance Company, The 0.00% No change 70,045 $145K
Exchange Traded Concepts, LLC 0.00% Add +32.2% 64,409 $133K
Two Sigma Investments, LP 0.00% Add +32.0% 56,933 $118K
XTX Topco Ltd 0.01% New 48,239 $100K
Two Sigma Advisers, LP 0.00% Reduce -5.9% 47,900 $99K
Cubist Systematic Strategies, LLC 0.00% New 40,102 $83K
Cerity Partners LLC 0.00% New 32,875 $68K
Dimensional Fund Advisors LP 0.00% Add +0.0% 29,082 $60K
Bank of New York Mellon Corp 0.00% Reduce -21.1% 28,613 $59K
Barclays PLC 0.00% Add +86.0% 27,165 $56K
Bank of America Corp. 0.00% Reduce -27.2% 24,944 $52K
HSBC Holdings PLC 0.00% Reduce -16.6% 20,772 $44K
Sherbrooke Park Advisers LLC 0.01% New 20,048 $41K
Connor, Clark & Lunn Investment Management Ltd. 0.00% Add +40.1% 17,293 $36K
Nuveen Asset Management, LLC 0.00% No change 16,797 $35K
Jump Financial, LLC 0.00% New 15,534 $32K
Citadel Advisors 0.00% Reduce -51.5% 15,225 $32K
Deutsche Bank AG 0.00% No change 14,618 $30K
Rhumbline Advisers 0.00% Reduce -44.3% 12,004 $25K
Verition Fund Management LLC 0.00% New 11,295 $23K
Jane Street Group, LLC 0.00% Reduce -20.0% 10,361 $21K
Citigroup Inc. 0.00% Add +220.3% 9,655 $20K
Simplex Trading, LLC 0.00% New 9,332 $19K
FMR LLC 0.00% Reduce -20.4% 7,618 $16K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -10.6% 7,271 $15K
Corebridge Financial, Inc. 0.00% Reduce -0.6% 7,049 $15K
UBS Group AG 0.00% Reduce -35.8% 7,016 $15K
Wells Fargo & Company 0.00% Add +4.5% 6,053 $13K
JPMorgan Chase & Co. 0.00% Add +1.8% 5,966 $12K
Tower Research Capital LLC (TRC) 0.00% Reduce -24.9% 5,302 $11K
Point72 (DIFC) Ltd 0.00% New 5,206 $11K
New York State Common Retirement Fund 0.00% Reduce -81.1% 3,622 $7K
Royal Bank of Canada 0.00% Reduce -2.9% 2,855 $6K
Legal & General Group Plc 0.00% No change 962 $2K
California State Teachers Retirement System 0.00% No change 955 $2K
Ameritas Investment Partners, Inc. 0.00% No change 819 $2K
Group One Trading LLC 0.00% New 500 $1K
Amalgamated Bank 0.00% No change 334 $1K
Russell Investments Group, Ltd. 0.00% Reduce -94.9% 76 $157
PNC Financial Services Group, Inc. 0.00% No change 64 $132
HighMark Wealth Management LLC 0.00% No change 50 $104
Sterling Capital Management LLC 0.00% — 42 $87
Arax Advisory Partners 0.00% No change 19 $40
Earned Wealth Advisors, LLC 0.00% New 8 $17
Cwm, LLC 0.00% Reduce -54.5% 10 $0

"% of holder's portfolio" is PRLD's weight in each manager's 13F, not the share of Prelude Therapeutics Inc. the manager owns.