Pyxis OncologyPYXS
13F holders, Q1 2026 (March 31)78holders −1
11new positions
13sold out
4famous investors
$1.47avg. 13F price*
At the end of Q1 2026, 78 institutions reported holding Pyxis Oncology Inc. (PYXS) in their 13F filings, down 1 from Q4 2025. 11 opened new positions and 13 sold out. The largest holders were Pfizer Inc ($9.2M), Laurion Capital Management LP ($7.3M) and GordonMD Global Investments LP ($6.0M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Pyxis Oncology Inc.
- CUSIP
- 747324101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 11 | $1.1M |
| Exits | 13 | $821K |
All 13F filers, Q4 2025 → Q1 2026: 1,197,529 shares bought and 3,820,926 shares sold, net −2,623,397 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 78 holders
| Pfizer Inc | 3.86% | No change | 7,032,770 | $9.2M |
| Laurion Capital Management LP | 0.72% | Add +4.2% | 4,997,333 | $7.3M |
| GordonMD Global Investments LP | 4.19% | No change | 4,121,870 | $6.0M |
| Vanguard Capital Management LLC | 0.00% | — | 2,033,510 | $3.0M |
| Atle Fund Management AB | 0.52% | Reduce -68.1% | 197,036 | $1.6M |
| Palo Alto Investors LP | 0.23% | Reduce -2.6% | 1,010,510 | $1.5M |
| 683 Capital Management, LLC | 0.13% | Add +0.5% | 896,263 | $1.3M |
| Renaissance Technologies | 0.00% | Add +22.0% | 888,680 | $1.3M |
| BlackRock, Inc. | 0.00% | Add +0.6% | 788,839 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Add +3.6% | 598,121 | $874K |
| Longaeva Partners L.P. | 0.04% | No change | 503,214 | $735K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 460,997 | $673K |
| Millennium Management | 0.00% | Reduce -46.5% | 397,625 | $581K |
| Marshall Wace, LLP | 0.00% | Reduce -9.1% | 354,417 | $517K |
| Decheng Capital LLC | 0.07% | No change | 326,810 | $477K |
| Jane Street Group, LLC | 0.00% | Reduce -61.3% | 304,459 | $445K |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 300,897 | $439K |
| UBS Group AG | 0.00% | Reduce -35.3% | 254,124 | $371K |
| State Street Corp. | 0.00% | Add +3.0% | 248,837 | $363K |
| XTX Topco Ltd | 0.01% | Reduce -30.8% | 200,096 | $292K |
| Acadian Asset Management LLC | 0.00% | New | 144,256 | $209K |
| Bank of New York Mellon Corp | 0.00% | Reduce -18.8% | 133,996 | $196K |
| NewEdge Wealth, LLC | 0.00% | No change | 116,006 | $169K |
| Northern Trust Corp. | 0.00% | No change | 101,948 | $149K |
| Bridgeway Capital Management, LLC | 0.00% | Add +11.8% | 81,260 | $119K |
| Two Sigma Investments, LP | 0.00% | Reduce -30.5% | 73,300 | $107K |
| Morgan Stanley | 0.00% | Reduce -21.9% | 69,688 | $102K |
| Panagora Asset Management Inc. | 0.00% | New | 69,424 | $101K |
| Cable Car Capital, LP | 0.04% | No change | 61,606 | $90K |
| Citadel Advisors | 0.00% | Reduce -74.9% | 61,249 | $89K |
| Stifel Financial Corp. | 0.00% | New | 50,537 | $74K |
| Toronto Dominion Bank | 0.00% | Reduce -33.3% | 50,000 | $73K |
| Barclays PLC | 0.00% | Reduce -17.5% | 49,825 | $73K |
| University of Chicago | 0.02% | No change | 48,731 | $71K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -45.5% | 46,920 | $69K |
| J. Derek Lewis & Associates Inc. | 0.01% | Reduce -18.9% | 43,000 | $63K |
| Susquehanna International Group, LLP | 0.00% | Reduce -62.0% | 41,201 | $60K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -12.6% | 34,755 | $51K |
| LPL Financial LLC | 0.00% | Reduce -4.4% | 33,554 | $49K |
| Point72 Asset Management | 0.00% | Reduce -83.0% | 32,006 | $47K |
| Cetera Investment Advisers | 0.00% | No change | 27,260 | $40K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -48.2% | 25,912 | $38K |
| Graham Capital Management, L.P. | 0.00% | Reduce -87.6% | 22,748 | $33K |
| Maia Wealth LLC | 0.01% | Reduce -3.1% | 21,277 | $31K |
| Vanguard Global Advisers, LLC | 0.00% | — | 21,242 | $31K |
| Catalyst Funds Management Pty Ltd | 0.01% | New | 20,400 | $30K |
| Squarepoint Ops LLC | 0.00% | New | 17,537 | $26K |
| Bank of America Corp. | 0.00% | Reduce -97.1% | 16,807 | $25K |
| Osaic Holdings, Inc. | 0.00% | Reduce -20.3% | 13,721 | $20K |
| Two Sigma Securities, LLC | 0.00% | New | 13,474 | $20K |
| FMR LLC | 0.00% | Reduce -7.4% | 11,912 | $17K |
| Paces Ferry Wealth Advisors, LLC | 0.01% | No change | 11,440 | $17K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -92.3% | 11,286 | $16K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +8.9% | 11,049 | $16K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -4.4% | 10,332 | $15K |
| NewEdge Advisors, LLC | 0.00% | No change | 10,250 | $15K |
| PNC Financial Services Group, Inc. | 0.00% | New | 6,500 | $9K |
| Winthrop Capital Management, LLC | 0.00% | No change | 6,000 | $9K |
| Royal Bank of Canada | 0.00% | Reduce -89.5% | 5,839 | $9K |
| Hager Investment Management Services, LLC | 0.00% | New | 5,000 | $7K |
| JPMorgan Chase & Co. | 0.00% | Reduce -6.2% | 5,173 | $7K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 3,248 | $5K |
| Federated Hermes, Inc. | 0.00% | Add +68.0% | 3,181 | $5K |
| Citigroup Inc. | 0.00% | Reduce -40.0% | 1,740 | $3K |
| BNP Paribas Financial Markets | 0.00% | Reduce -93.2% | 1,654 | $2K |
| GF Fund Management Co. LTD. | 0.00% | Add +3.0% | 1,316 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 961 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 943 | $1K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -91.0% | 743 | $1K |
| Jones Financial Companies LLLP | 0.00% | No change | 500 | $655 |
| Wells Fargo & Company | 0.00% | Reduce -87.5% | 285 | $416 |
| Simplex Trading, LLC | 0.00% | Reduce -97.4% | 253 | $369 |
| Cornerstone Financial Management LLC | 0.00% | No change | 172 | $251 |
| Cwm, LLC | 0.00% | Reduce -51.4% | 34 | $50 |
| Arax Advisory Partners | 0.00% | Reduce -92.9% | 1 | $20 |
| Ascentis Independent Advisors | 0.00% | New | 10 | $14 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 4 | $6 |
| SBI Securities Co., Ltd. | 0.00% | No change | 1 | $1 |
"% of holder's portfolio" is PYXS's weight in each manager's 13F, not the share of Pyxis Oncology Inc. the manager owns.