Pyxis OncologyPYXS
13F holders, Q2 2025 (June 30)74holders −15
15new positions
30sold out
3famous investors
$1.10avg. 13F price*
At the end of Q2 2025, 74 institutions reported holding Pyxis Oncology Inc. (PYXS) in their 13F filings, down 15 from Q1 2025. 15 opened new positions and 30 sold out. The largest holders were Pfizer Inc ($7.7M), Laurion Capital Management LP ($4.0M) and Millennium Management ($3.9M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Pyxis Oncology Inc.
- CUSIP
- 747324101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $976K |
| Exits | 30 | $1.5M |
All 13F filers, Q1 2025 → Q2 2025: 3,834,721 shares bought and 6,628,059 shares sold, net −2,793,338 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 74 holders
| Pfizer Inc | 1.34% | No change | 7,032,770 | $7.7M |
| Laurion Capital Management LP | 0.48% | No change | 3,625,974 | $4.0M |
| Millennium Management | 0.00% | Add +42.4% | 3,539,860 | $3.9M |
| Tang Capital Management LLC | 0.14% | Add +127.3% | 2,500,000 | $2.8M |
| Vanguard Group Inc. | 0.00% | Reduce -11.8% | 2,149,396 | $2.4M |
| Palo Alto Investors LP | 0.24% | No change | 1,037,421 | $1.1M |
| BlackRock, Inc. | 0.00% | Reduce -71.7% | 926,805 | $1.0M |
| Aberdeen Group plc | 0.00% | No change | 913,045 | $1.0M |
| 683 Capital Management, LLC | 0.06% | Reduce -0.9% | 545,000 | $600K |
| Geode Capital Management, LLC | 0.00% | Reduce -53.9% | 510,963 | $562K |
| Renaissance Technologies | 0.00% | Reduce -28.2% | 417,822 | $460K |
| UBS Group AG | 0.00% | Reduce -0.2% | 396,096 | $436K |
| Pier 88 Investment Partners LLC | 0.43% | Reduce -6.1% | 367,170 | $404K |
| Jane Street Group, LLC | 0.00% | New | 336,084 | $370K |
| Decheng Capital LLC | 0.09% | No change | 326,810 | $359K |
| Schulhoff & Co. Inc. | 0.13% | Add +125.4% | 275,000 | $303K |
| Goldman Sachs Group Inc. | 0.00% | Add +39.5% | 224,274 | $247K |
| State Street Corp. | 0.00% | Reduce -80.0% | 186,055 | $205K |
| Bank of New York Mellon Corp | 0.00% | Reduce -39.5% | 165,044 | $182K |
| Morgan Stanley | 0.00% | Reduce -64.1% | 160,174 | $176K |
| Marshall Wace, LLP | 0.00% | New | 147,771 | $163K |
| Bridgeway Capital Management, LLC | 0.00% | Add +76.1% | 142,295 | $157K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 133,047 | $146K |
| Susquehanna International Group, LLP | 0.00% | Add +76.2% | 114,359 | $126K |
| NewEdge Wealth, LLC | 0.00% | No change | 116,006 | $124K |
| Qube Research & Technologies Ltd | 0.00% | Add +128.4% | 103,063 | $113K |
| Northern Trust Corp. | 0.00% | Reduce -72.7% | 102,216 | $112K |
| FMR LLC | 0.00% | Add +9.4% | 94,846 | $104K |
| AQR Capital Management | 0.00% | Add +115.5% | 86,763 | $95K |
| Royal Bank of Canada | 0.00% | Reduce -10.7% | 86,365 | $95K |
| Cable Car Capital, LP | 0.06% | No change | 61,606 | $68K |
| Commonwealth Equity Services, LLC | 0.00% | Add +41.4% | 61,155 | $67K |
| HRT Financial LP | 0.00% | New | 50,668 | $55K |
| University of Chicago | 0.05% | No change | 48,731 | $54K |
| Jain Global LLC | 0.00% | New | 48,649 | $54K |
| Velan Capital Investment Management LP | 0.04% | New | 40,000 | $44K |
| Dimensional Fund Advisors LP | 0.00% | No change | 36,516 | $40K |
| XTX Topco Ltd | 0.00% | New | 36,380 | $40K |
| Squarepoint Ops LLC | 0.00% | Add +137.6% | 35,428 | $39K |
| Cetera Investment Advisers | 0.00% | Add +3.2% | 28,760 | $32K |
| Catalyst Funds Management Pty Ltd | 0.01% | New | 23,200 | $26K |
| Bank of America Corp. | 0.00% | Reduce -45.3% | 22,069 | $24K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | New | 19,228 | $21K |
| Acadian Asset Management LLC | 0.00% | Reduce -77.5% | 18,942 | $20K |
| Osaic Holdings, Inc. | 0.00% | Reduce -20.8% | 17,721 | $19K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +31.4% | 14,657 | $16K |
| LPL Financial LLC | 0.00% | Reduce -11.8% | 14,199 | $16K |
| Hudson Bay Capital Management LP | 0.00% | New | 13,790 | $15K |
| DRW Securities, LLC | 0.00% | New | 13,042 | $14K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +4.3% | 12,442 | $14K |
| Quadrature Capital Ltd | 0.00% | New | 12,334 | $14K |
| Simplex Trading, LLC | 0.00% | Add +43.3% | 12,615 | $13K |
| Mercer Global Advisors Inc. | 0.00% | New | 10,004 | $11K |
| Citigroup Inc. | 0.00% | Reduce -74.5% | 8,927 | $10K |
| Winthrop Capital Management, LLC | 0.00% | No change | 6,000 | $7K |
| Cwm, LLC | 0.00% | Add +93.0% | 6,536 | $7K |
| Barclays PLC | 0.00% | Reduce -91.0% | 4,854 | $5K |
| Raymond James Financial Inc. | 0.00% | New | 3,231 | $4K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +20.3% | 2,393 | $3K |
| JPMorgan Chase & Co. | 0.00% | Reduce -92.7% | 2,068 | $2K |
| BNP Paribas Financial Markets | 0.00% | Reduce -50.0% | 1,833 | $2K |
| Jones Financial Companies LLLP | 0.00% | No change | 1,500 | $2K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,429 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | Add +220.3% | 961 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | New | 943 | $1K |
| Wells Fargo & Company | 0.00% | Reduce -97.7% | 699 | $769 |
| Group One Trading LLC | 0.00% | Reduce -80.0% | 602 | $662 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +22.1% | 591 | $650 |
| True Wealth Design, LLC | 0.00% | Add +3842.9% | 276 | $304 |
| NewEdge Advisors, LLC | 0.00% | No change | 250 | $275 |
| Russell Investments Group, Ltd. | 0.00% | No change | 64 | $70 |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 12 | $13 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -50.0% | 1 | $1 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -66.7% | 1 | $1 |
"% of holder's portfolio" is PYXS's weight in each manager's 13F, not the share of Pyxis Oncology Inc. the manager owns.