Relay TherapeuticsRLAY
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 244 institutions reported holding Relay Therapeutics Inc. (RLAY) in their 13F filings, up 17 from Q4 2025. 44 opened new positions and 27 sold out. The largest holders were SB Investment Advisers (uk) Ltd. ($277.7M), Commodore Capital LP ($169.2M) and Casdin Capital, LLC ($143.5M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Relay Therapeutics Inc.
- CUSIP
- 75943R102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 44 | $92.3M |
| Exits | 27 | $141.8M |
All 13F filers, Q4 2025 → Q1 2026: 33,004,612 shares bought and 21,378,956 shares sold, net +11,625,656 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 244 holders
| SB Investment Advisers (uk) Ltd. | 3.59% | No change | 27,904,963 | $277.7M |
| Commodore Capital LP | 9.79% | No change | 17,000,000 | $169.2M |
| Casdin Capital, LLC | 10.86% | Add +10.9% | 14,418,574 | $143.5M |
| BlackRock, Inc. | 0.00% | Reduce -1.9% | 12,975,299 | $129.1M |
| Perceptive Advisors LLC | 1.92% | Add +412.3% | 9,751,141 | $97.0M |
| Bellevue Group AG | 1.85% | Reduce -6.6% | 7,795,242 | $77.6M |
| Vanguard Capital Management LLC | 0.00% | — | 7,387,465 | $73.5M |
| State Street Corp. | 0.00% | Reduce -3.0% | 6,233,545 | $62.0M |
| Nextech Invest Ltd. | 3.87% | Add +17.6% | 5,526,506 | $55.0M |
| TCG Crossover Management, LLC | 1.22% | Add +32.7% | 4,273,356 | $42.5M |
| FMR LLC | 0.00% | Add +2178.0% | 3,695,431 | $36.8M |
| Geode Capital Management, LLC | 0.00% | Add +3.0% | 3,510,636 | $34.9M |
| Balyasny Asset Management L.P. | 0.06% | Add +44.7% | 3,039,179 | $30.2M |
| Spruce Street Capital LP | 7.14% | No change | 2,984,125 | $29.7M |
| Dimensional Fund Advisors LP | 0.01% | Add +18.6% | 2,940,536 | $29.2M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Add +418.0% | 2,590,000 | $25.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +36.7% | 2,541,861 | $25.3M |
| MPM Bioimpact LLC | 1.81% | Add +5.7% | 2,359,586 | $23.5M |
| Bank of America Corp. | 0.00% | Add +86.2% | 1,937,695 | $19.3M |
| T. Rowe Price Associates Inc. | 0.00% | Add +17.0% | 1,924,938 | $19.2M |
| EcoR1 Capital, LLC | 0.81% | New | 1,904,762 | $19.0M |
| Vanguard Portfolio Management LLC | 0.00% | — | 1,863,565 | $18.5M |
| Northern Trust Corp. | 0.00% | Add +47.1% | 1,675,387 | $16.7M |
| Alphabet Inc. | 0.39% | Reduce -0.3% | 1,564,173 | $15.6M |
| Morgan Stanley | 0.00% | Reduce -29.1% | 1,432,003 | $14.2M |
| Kynam Capital Management, LP | 0.90% | No change | 1,424,259 | $14.2M |
| Two Sigma Investments, LP | 0.01% | Reduce -12.3% | 1,369,149 | $13.6M |
| AQR Capital Management | 0.01% | Add +10.9% | 1,290,032 | $12.8M |
| Baker Bros. Advisors LP | 0.07% | No change | 1,160,117 | $11.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.2% | 1,111,891 | $11.1M |
| Foresite Capital Management IV, LLC | 4.20% | No change | 1,000,000 | $9.9M |
| Marshall Wace, LLP | 0.01% | New | 941,825 | $9.4M |
| Kalehua Capital Management LLC | 6.35% | No change | 901,457 | $9.0M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 900,546 | $9.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +114.9% | 837,038 | $8.3M |
| Panagora Asset Management Inc. | 0.03% | New | 818,041 | $8.1M |
| Logos Global Management LP | 0.38% | New | 750,000 | $7.5M |
| Woodline Partners LP | 0.03% | Add +0.0% | 679,342 | $6.8M |
| Renaissance Technologies | 0.01% | Add +4.0% | 673,599 | $6.7M |
| Squadron Capital Management LLC | 2.68% | New | 672,500 | $6.7M |
| Invesco Ltd. | 0.00% | Reduce -22.6% | 669,874 | $6.7M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 668,289 | $6.6M |
| Qube Research & Technologies Ltd | 0.01% | New | 619,652 | $6.2M |
| Congress Asset Management Co. | 0.04% | Add +49.4% | 618,938 | $6.2M |
| JPMorgan Chase & Co. | 0.00% | Add +52.0% | 647,518 | $6.1M |
| ArrowMark Colorado Holdings LLC | 0.14% | No change | 541,124 | $5.4M |
| Elmind Capital, LP | 1.52% | No change | 536,946 | $5.3M |
| UBS Group AG | 0.00% | Add +78.2% | 527,611 | $5.2M |
| Timothy G. Youngquist 2020 Irrevocable Trust | 2.43% | No change | 499,058 | $5.0M |
| Longaeva Partners L.P. | 0.23% | New | 470,544 | $4.7M |
| Bessemer Group Inc. | 0.01% | No change | 457,869 | $4.6M |
| American Century Companies Inc. | 0.00% | Add +1.8% | 440,185 | $4.4M |
| Jane Street Group, LLC | 0.00% | Add +453.8% | 423,536 | $4.2M |
| HighVista Strategies LLC | 1.16% | Reduce -22.6% | 421,881 | $4.2M |
| Sphera Funds Management LTD. | 0.70% | New | 408,436 | $4.1M |
| Affinity Asset Advisors, LLC | 0.24% | New | 400,000 | $4.0M |
| Bank of New York Mellon Corp | 0.00% | Add +1.1% | 382,920 | $3.8M |
| Rhenman & Partners Asset Management AB | 0.44% | Reduce -21.7% | 360,000 | $3.6M |
| Ameriprise Financial Inc. | 0.00% | New | 356,924 | $3.6M |
| Millennium Management | 0.00% | Reduce -61.2% | 347,733 | $3.5M |
| Raymond James Financial Inc. | 0.00% | Add +33.5% | 346,317 | $3.4M |
| Susquehanna Portfolio Strategies, LLC | 0.05% | No change | 339,080 | $3.4M |
| Hudson Bay Capital Management LP | 0.02% | Reduce -31.1% | 311,330 | $3.1M |
| Nuveen, LLC | 0.00% | Add +0.6% | 302,196 | $3.0M |
| Acadian Asset Management LLC | 0.00% | Reduce -36.4% | 290,352 | $2.9M |
| Exome Asset Management LLC | 1.63% | New | 278,302 | $2.8M |
| Eversept Partners, LP | 0.18% | Reduce -44.7% | 270,705 | $2.7M |
| Seven Fleet Capital Management LP | 0.81% | Add +253.1% | 257,738 | $2.6M |
| Swiss National Bank | 0.00% | No change | 238,000 | $2.4M |
| Rhumbline Advisers | 0.00% | Add +0.6% | 216,933 | $2.2M |
| Voya Investment Management LLC | 0.00% | Add +779.1% | 216,052 | $2.1M |
| TD Asset Management Inc | 0.00% | Add +17.7% | 214,170 | $2.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.3% | 210,468 | $2.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +18.1% | 209,707 | $2.1M |
| Ieq Capital, LLC | 0.01% | Add +26.5% | 205,310 | $2.0M |
| SG Americas Securities, LLC | 0.00% | Reduce -10.6% | 197,535 | $2.0M |
| XTX Topco Ltd | 0.03% | Add +20.0% | 188,940 | $1.9M |
| Osaic Holdings, Inc. | 0.00% | Reduce -0.1% | 186,123 | $1.9M |
| Tetragon Partners GP Ltd | 0.35% | New | 181,543 | $1.8M |
| Squarepoint Ops LLC | 0.00% | Add +91.4% | 180,298 | $1.8M |
| Raiffeisen Bank International AG | 0.03% | Reduce -24.0% | 190,000 | $1.8M |
| Citadel Advisors | 0.00% | Add +54.4% | 176,265 | $1.8M |
| California State Teachers Retirement System | 0.00% | Add +48.0% | 174,099 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Add +60.4% | 162,236 | $1.6M |
| Tema ETFs LLC | 0.10% | Add +38.1% | 154,100 | $1.5M |
| Tidal Investments LLC | 0.00% | New | 154,100 | $1.5M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -22.3% | 150,618 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Reduce -34.0% | 147,158 | $1.5M |
| Alps Advisors Inc. | 0.01% | Add +2.2% | 145,490 | $1.4M |
| Sanctuary Advisors, LLC | 0.01% | Add +1.1% | 143,816 | $1.4M |
| Engineers Gate Manager LP | 0.02% | Add +80.5% | 141,452 | $1.4M |
| Deutsche Bank AG | 0.00% | Add +4.5% | 129,612 | $1.3M |
| Alliancebernstein L.P. | 0.00% | No change | 145,251 | $1.2M |
| Man Group plc | 0.00% | Add +29.6% | 112,843 | $1.1M |
| Wells Fargo & Company | 0.00% | Reduce -30.4% | 109,952 | $1.1M |
| Creative Planning | 0.00% | Add +18.1% | 101,349 | $1.0M |
| ICONIQ Capital, LLC | 0.02% | No change | 94,697 | $942K |
| Trexquant Investment LP | 0.01% | Reduce -80.0% | 94,248 | $938K |
| Himension Capital (singapore) Pte. LTD. | 0.07% | Reduce -10.3% | 94,169 | $937K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 82,300 | $819K |
| Legal & General Group Plc | 0.00% | Reduce -24.9% | 82,056 | $816K |
| Victory Capital Management Inc. | 0.00% | Add +432.7% | 79,994 | $796K |
| MetLife Investment Management, LLC | 0.00% | Add +1.9% | 79,024 | $786K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +11.1% | 72,739 | $783K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -0.0% | 76,661 | $756K |
| Vanguard Global Advisers, LLC | 0.00% | — | 75,079 | $747K |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +16.2% | 71,880 | $715K |
| Cwm, LLC | 0.00% | Add +3.5% | 69,959 | $696K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +16.3% | 55,384 | $695K |
| Profund Advisors LLC | 0.02% | Reduce -6.1% | 68,170 | $678K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +16.6% | 66,739 | $664K |
| Janus Henderson Group PLC | 0.00% | Add +77.8% | 65,573 | $652K |
| J. Goldman & Co LP | 0.03% | Add +407.0% | 63,637 | $633K |
| Prelude Capital Management, LLC | 0.05% | New | 61,899 | $616K |
| Wellington Management Group LLP | 0.00% | New | 59,508 | $592K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $591K |
| Bank of Montreal | 0.00% | Reduce -6.2% | 52,943 | $527K |
| Franklin Resources Inc. | 0.00% | No change | 48,915 | $487K |
| Algert Global LLC | 0.01% | Reduce -66.9% | 48,510 | $483K |
| Aquatic Capital Management LLC | 0.01% | New | 48,120 | $479K |
| Headlands Technologies LLC | 0.05% | New | 47,626 | $474K |
| New York State Common Retirement Fund | 0.00% | No change | 45,799 | $456K |
| Barclays PLC | 0.00% | Reduce -89.1% | 45,267 | $450K |
| Intellectus Partners, LLC | 0.09% | Reduce -3.9% | 42,225 | $420K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 41,464 | $413K |
| LPL Financial LLC | 0.00% | Add +18.5% | 40,463 | $403K |
| BNP Paribas Financial Markets | 0.00% | Add +97.3% | 39,467 | $393K |
| Brandywine Managers, LLC | 0.23% | No change | 38,429 | $382K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 37,005 | $368K |
| Captrust Financial Advisors | 0.00% | Add +3.4% | 36,769 | $366K |
| Cresset Asset Management, LLC | 0.00% | Reduce -1.6% | 36,495 | $363K |
| Sei Investments Co. | 0.00% | Add +41.0% | 36,130 | $359K |
| Mariner, LLC | 0.00% | New | 36,096 | $358K |
| Valeo Financial Advisors, LLC | 0.01% | New | 35,714 | $355K |
| Virtus Investment Advisers, LLC | 0.09% | Add +2.5% | 33,957 | $338K |
| Gotham Asset Management | 0.00% | New | 33,606 | $334K |
| Arizona State Retirement System | 0.00% | Reduce -0.6% | 33,325 | $332K |
| Brooklyn Investment Group | 0.01% | Add +20.0% | 32,577 | $324K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +12.3% | 31,716 | $316K |
| Intech Investment Management LLC | 0.00% | Reduce -40.6% | 31,617 | $315K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +14.5% | 31,582 | $314K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 30,117 | $300K |
| Citigroup Inc. | 0.00% | Reduce -3.8% | 29,754 | $296K |
| OP Asset Management Ltd | 0.00% | New | 29,217 | $291K |
| Pallas Capital Advisors LLC | 0.01% | Add +13.8% | 28,573 | $284K |
| ProShare Advisors LLC | 0.00% | Reduce -14.9% | 28,409 | $283K |
| Fiduciary Trust Co | 0.00% | No change | 27,971 | $278K |
| KLP Kapitalforvaltning As | 0.00% | Add +10.1% | 27,200 | $271K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 25,807 | $257K |
| Nomura Holdings Inc. | 0.00% | New | 25,000 | $249K |
| Cerity Partners LLC | 0.00% | Add +15.0% | 24,195 | $241K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | Add +79.8% | 23,200 | $231K |
| Oxford Asset Management LLP | 0.09% | New | 22,521 | $224K |
| Aigen Investment Management, LP | 0.06% | New | 22,075 | $220K |
| Erste Asset Management GmbH | 0.00% | No change | 23,100 | $216K |
| Amundi | 0.00% | New | 21,381 | $213K |
| Prudential Financial Inc. | 0.00% | New | 21,350 | $212K |
| Quantinno Capital Management LP | 0.00% | Add +22.6% | 21,188 | $211K |
| Quadrature Capital Ltd | 0.00% | New | 21,123 | $210K |
| Merit Financial Group, LLC | 0.00% | Add +2.5% | 21,000 | $209K |
| Pictet Asset Management Holding SA | 0.00% | Add +30.2% | 19,592 | $195K |
| E Fund Management Co., Ltd. | 0.01% | — | 18,933 | $188K |
| Abel Hall, LLC | 0.04% | Add +40.5% | 18,237 | $181K |
| Callan Family Office, LLC | 0.00% | Reduce -12.9% | 17,890 | $178K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 17,516 | $174K |
| Russell Investments Group, Ltd. | 0.00% | Add +35.1% | 16,840 | $168K |
| Mercer Global Advisors Inc. | 0.00% | Add +27.9% | 16,421 | $163K |
| Persistent Asset Partners Ltd | 0.06% | New | 16,358 | $163K |
| Teacher Retirement System of Texas | 0.00% | Reduce -9.2% | 15,868 | $158K |
| DNB Asset Management AS | 0.00% | New | 15,814 | $157K |
| Mirabella Financial Services LLP | 0.02% | New | 15,121 | $150K |
| AssuredPartners Investment Advisors, LLC | 0.02% | Reduce -25.2% | 12,062 | $150K |
| Fox Run Management, L.L.C. | 0.03% | Reduce -74.6% | 15,284 | $143K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 13,869 | $138K |
| Xponance LLC | 0.00% | Add +16.8% | 12,852 | $128K |
| Gabelli Funds LLC | 0.00% | New | 12,000 | $119K |
| Quadrant Capital Group LLC | 0.00% | No change | 11,791 | $117K |
| Focus Partners Advisor Solutions, LLC | 0.00% | Add +9.1% | 11,631 | $115K |
| Duncan Williams Asset Management, LLC | 0.03% | Reduce -2.8% | 11,438 | $114K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 11,180 | $111K |
| 49 Wealth Management, LLC | 0.01% | Reduce -3.3% | 11,029 | $110K |
| Plante Moran Financial Advisors, LLC | 0.01% | Add +23.6% | 10,836 | $108K |
| Focus Partners Wealth | 0.00% | Reduce -37.9% | 10,756 | $107K |
| HighTower Advisors, LLC | 0.00% | New | 10,738 | $107K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1474.0% | 10,719 | $107K |
| EP Wealth Advisors, LLC | 0.00% | Reduce -16.5% | 10,434 | $104K |
| Neuberger Berman Group LLC | 0.00% | New | 10,048 | $100K |
| Portland Investment Counsel Inc. | 0.03% | No change | 10,000 | $100K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +10.7% | 9,322 | $93K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 8,624 | $86K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -9.0% | 8,100 | $81K |
| Group One Trading LLC | 0.00% | Reduce -77.1% | 6,638 | $66K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,888 | $59K |
| Essential Partners LLC | 0.02% | Add +0.2% | 5,358 | $53K |
| US Bancorp \de | 0.00% | Add +2.0% | 5,232 | $52K |
| FNY Investment Advisers, LLC | 0.02% | No change | 5,000 | $49K |
| Sterling Capital Management LLC | 0.00% | Reduce -42.5% | 4,665 | $46K |
| Farther Finance Advisors, LLC | 0.00% | Add +3.9% | 4,301 | $46K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -2.5% | 4,493 | $45K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -0.3% | 4,415 | $41K |
| Nisa Investment Advisors, LLC | 0.00% | Add +87.2% | 3,882 | $39K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.8% | 3,876 | $39K |
| KBC Group NV | 0.00% | New | 3,448 | $34K |
| Signaturefd, LLC | 0.00% | No change | 3,124 | $31K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -93.8% | 2,989 | $30K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +30.1% | 2,876 | $29K |
| Caitong International Asset Management Co., Ltd | 0.01% | Reduce -79.5% | 2,790 | $28K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +38.4% | 2,449 | $24K |
| Rockefeller Capital Management L.P. | 0.00% | Add +398.5% | 2,263 | $23K |
| Hager Investment Management Services, LLC | 0.01% | No change | 2,178 | $22K |
| Allworth Financial LP | 0.00% | Add +29.6% | 1,729 | $17K |
| Advisory Services Network, LLC | 0.00% | New | 1,697 | $17K |
| SBI Securities Co., Ltd. | 0.00% | Add +0.8% | 1,464 | $15K |
| Kemnay Advisory Services Inc. | 0.00% | New | 1,448 | $14K |
| Parallel Advisors, LLC | 0.00% | Add +4.0% | 1,237 | $12K |
| GAMMA Investing LLC | 0.00% | Add +229.4% | 1,166 | $12K |
| Quantbot Technologies LP | 0.00% | New | 1,054 | $10K |
| Webster Bank, N. A. | 0.00% | No change | 1,000 | $10K |
| MAI Capital Management | 0.00% | Add +310.5% | 743 | $7K |
| UMB Bank, n.a. | 0.00% | No change | 735 | $7K |
| Red Tortoise LLC | 0.00% | No change | 698 | $7K |
| Keating Financial Advisory Services, Inc. | 0.00% | No change | 679 | $7K |
| Fifth Third Bancorp | 0.00% | New | 664 | $7K |
| IFP Advisors, Inc | 0.00% | No change | 576 | $6K |
| Rothschild Investment LLC | 0.00% | Add +15.1% | 540 | $5K |
| Versant Capital Management, Inc | 0.00% | No change | 493 | $5K |
| Fortitude Family Office, LLC | 0.00% | Add +34.5% | 405 | $4K |
| Jones Financial Companies LLLP | 0.00% | Add +127.3% | 350 | $3K |
| Basecamp Wealth Advisors LLC | 0.00% | Add +3.1% | 300 | $3K |
| True Wealth Design, LLC | 0.00% | No change | 278 | $3K |
| Arax Advisory Partners | 0.00% | Add +1094.7% | 227 | $2K |
| Cornerstone Financial Management LLC | 0.00% | No change | 162 | $2K |
| Parkside Financial Bank & Trust | 0.00% | No change | 129 | $1K |
| International Assets Investment Management, LLC | 0.00% | No change | 93 | $1K |
| Avion Wealth | 0.00% | No change | 136 | $1K |
| Royal Bank of Canada | 0.00% | Reduce -96.4% | 146 | $1K |
| Your Advocates Ltd., LLP | 0.00% | No change | 100 | $995 |
| Root Financial Partners, LLC | 0.00% | New | 93 | $925 |
| Hughes Financial Services, LLC | 0.00% | Reduce -60.1% | 87 | $866 |
| Sunbelt Securities, Inc. | 0.00% | No change | 52 | $517 |
| Clearstead Advisors, LLC | 0.00% | Reduce -32.4% | 23 | $225 |
| Transamerica Financial Advisors, LLC | 0.00% | No change | 13 | $129 |
| JPL Wealth Management, LLC | 0.00% | New | 3 | $30 |
| Covestor Ltd | 0.00% | Reduce -29.2% | 17 | $0 |
"% of holder's portfolio" is RLAY's weight in each manager's 13F, not the share of Relay Therapeutics Inc. the manager owns.