Xenon PharmaceuticalsXENE
13F holders, Q2 2025 (June 30)206holders
42new positions
39sold out
5famous investors
$31.30avg. 13F price*
At the end of Q2 2025, 206 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, unchanged from Q1 2025. 42 opened new positions and 39 sold out. The largest holders were FMR LLC ($278.1M), Avoro Capital Advisors LLC ($169.0M) and BlackRock, Inc. ($167.9M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 42 | $150.7M |
| Exits | 39 | $141.0M |
All 13F filers, Q1 2025 → Q2 2025: 19,022,618 shares bought and 12,528,093 shares sold, net +6,494,525 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 206 holders
| FMR LLC | 0.02% | Add +7.2% | 8,884,363 | $278.1M |
| Avoro Capital Advisors LLC | 2.96% | Reduce -6.0% | 5,400,000 | $169.0M |
| BlackRock, Inc. | 0.00% | Add +163.5% | 5,365,327 | $167.9M |
| Driehaus Capital Management LLC | 1.09% | Reduce -5.4% | 4,335,648 | $135.7M |
| Braidwell LP | 5.40% | Add +33.0% | 3,605,029 | $112.8M |
| Janus Henderson Group PLC | 0.05% | Add +7.6% | 3,577,735 | $112.0M |
| Capital International Investors | 0.02% | Add +3.0% | 3,181,549 | $99.6M |
| Commodore Capital LP | 6.68% | Add +30.1% | 3,025,000 | $94.7M |
| Polar Capital Holdings Plc | 0.45% | Add +3.1% | 2,703,256 | $84.6M |
| Wellington Management Group LLP | 0.01% | Reduce -42.6% | 2,174,761 | $68.1M |
| Vestal Point Capital, LP | 3.30% | Add +53.9% | 2,000,000 | $62.6M |
| Holocene Advisors, LP | 0.14% | New | 1,809,475 | $56.6M |
| Alliancebernstein L.P. | 0.02% | Add +14.2% | 1,518,527 | $47.5M |
| Pictet Asset Management Holding SA | 0.05% | Reduce -0.2% | 1,474,449 | $46.2M |
| State Street Corp. | 0.00% | Add +351.7% | 1,380,460 | $43.2M |
| Deep Track Capital, LP | 1.36% | Add +35.0% | 1,350,000 | $42.3M |
| Adage Capital Partners Gp, L.L.C. | 0.07% | Reduce -32.6% | 1,290,100 | $40.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -7.4% | 1,256,581 | $39.3M |
| Westfield Capital Management Co. LP | 0.15% | Reduce -17.2% | 1,152,605 | $36.1M |
| Affinity Asset Advisors, LLC | 5.31% | Reduce -17.2% | 1,100,000 | $34.4M |
| Marshall Wace, LLP | 0.04% | Add +34.6% | 1,020,254 | $31.9M |
| Geode Capital Management, LLC | 0.00% | Add +1294.2% | 970,343 | $30.4M |
| Orbimed Advisors LLC | 0.75% | No change | 947,877 | $29.7M |
| Rock Springs Capital Management LP | 1.82% | No change | 931,681 | $29.2M |
| Millennium Management | 0.03% | Add +277.2% | 882,835 | $27.6M |
| Vanguard Group Inc. | 0.00% | Add +159.5% | 873,228 | $27.3M |
| Siren, L.L.C. | 1.32% | Add +10.9% | 812,761 | $25.4M |
| Jennison Associates LLC | 0.01% | Reduce -10.3% | 696,383 | $21.8M |
| American Century Companies Inc. | 0.01% | New | 679,857 | $21.3M |
| Franklin Resources Inc. | 0.01% | Add +35.7% | 666,466 | $20.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.05% | Reduce -6.1% | 661,082 | $20.7M |
| First Turn Management, LLC | 3.86% | Reduce -3.3% | 660,617 | $20.7M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -2.4% | 657,165 | $20.6M |
| Capital World Investors | 0.00% | Reduce -70.5% | 655,737 | $20.5M |
| TimesSquare Capital Management, LLC | 0.26% | Reduce -23.4% | 571,242 | $17.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +26.9% | 561,800 | $17.6M |
| Deerfield Management Company, L.P. | 0.34% | New | 542,020 | $17.0M |
| Fiera Capital Corp | 0.06% | Add +0.2% | 530,683 | $16.6M |
| Aberdeen Group plc | 0.03% | Add +29.0% | 521,492 | $16.3M |
| Northern Trust Corp. | 0.00% | Add +504.7% | 489,940 | $15.3M |
| Saturn V Capital Management LP | 5.94% | Add +13.2% | 468,364 | $14.7M |
| Assenagon Asset Management S.A. | 0.02% | Add +81.2% | 436,974 | $13.7M |
| Bank of New York Mellon Corp | 0.00% | Add +73.6% | 436,020 | $13.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +536.1% | 404,384 | $12.7M |
| Candriam S.C.A. | 0.07% | Reduce -12.8% | 396,636 | $12.4M |
| Morgan Stanley | 0.00% | Add +199.3% | 387,596 | $12.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +76.8% | 379,988 | $11.9M |
| Baker Bros. Advisors LP | 0.11% | Add +6.6% | 370,208 | $11.6M |
| Bank of America Corp. | 0.00% | Add +162.4% | 358,432 | $11.2M |
| MPM Bioimpact LLC | 1.75% | Add +6.6% | 323,398 | $10.1M |
| DAFNA Capital Management LLC | 2.52% | Add +5.2% | 287,939 | $9.0M |
| ADAR1 Capital Management, LLC | 1.33% | Add +103.5% | 259,503 | $8.1M |
| Granahan Investment Management, LLC | 0.31% | Add +30.6% | 240,038 | $7.5M |
| DNB Asset Management AS | 0.03% | Add +2.0% | 234,157 | $7.3M |
| Federated Hermes, Inc. | 0.01% | No change | 232,500 | $7.3M |
| Nuveen, LLC | 0.00% | New | 228,567 | $7.2M |
| Susquehanna International Group, LLP | 0.01% | New | 222,352 | $7.0M |
| Perceptive Advisors LLC | 0.24% | Reduce -38.3% | 200,791 | $6.3M |
| Great Point Partners LLC | 4.07% | Reduce -18.5% | 200,000 | $6.3M |
| Charles Schwab Investment Management Inc. | 0.00% | New | 192,242 | $6.0M |
| First Light Asset Management, LLC | 0.76% | Reduce -70.0% | 188,367 | $5.9M |
| AXA S.A. | 0.02% | Add +0.2% | 175,632 | $5.5M |
| State of Wisconsin Investment Board | 0.01% | Add +80.0% | 174,850 | $5.5M |
| New York State Common Retirement Fund | 0.01% | Add +16.9% | 166,472 | $5.2M |
| Foresite Capital Management IV, LLC | 4.05% | New | 160,000 | $5.0M |
| Foresite Capital Management VI LLC | 2.82% | New | 160,000 | $5.0M |
| Nan Fung Trinity (hk) Ltd. | 0.59% | New | 158,605 | $5.0M |
| UBS Group AG | 0.00% | Add +45.3% | 153,058 | $4.8M |
| Barclays PLC | 0.00% | Add +692.8% | 152,770 | $4.8M |
| Parkman Healthcare Partners LLC | 0.54% | Reduce -13.9% | 150,373 | $4.7M |
| Neuberger Berman Group LLC | 0.00% | Add +228.7% | 147,411 | $4.6M |
| Royal Bank of Canada | 0.00% | Add +148.0% | 147,226 | $4.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -6.8% | 141,783 | $4.4M |
| Schroder Investment Management Group | 0.00% | Reduce -5.9% | 129,103 | $4.0M |
| Swiss National Bank | 0.00% | Reduce -1.0% | 124,300 | $3.9M |
| Ameriprise Financial Inc. | 0.00% | Add +17.8% | 122,026 | $3.8M |
| Citadel Advisors | 0.00% | Reduce -82.5% | 120,045 | $3.8M |
| Wells Fargo & Company | 0.00% | Add +70.8% | 112,562 | $3.5M |
| Rhumbline Advisers | 0.00% | Add +378175.9% | 109,700 | $3.4M |
| Avidity Partners Management LP | 0.68% | Reduce -52.9% | 107,891 | $3.4M |
| Deutsche Bank AG | 0.00% | Add +94.6% | 104,534 | $3.3M |
| Algert Global LLC | 0.07% | Reduce -17.1% | 102,345 | $3.2M |
| Caption Management, LLC | 0.29% | New | 100,940 | $3.2M |
| Mutual of America Capital Management LLC | 0.03% | Add +96.0% | 95,568 | $3.0M |
| Two Sigma Advisers, LP | 0.01% | Reduce -68.1% | 95,300 | $3.0M |
| Moore Capital Management, LP | 0.06% | Add +63.6% | 90,000 | $2.8M |
| J. Safra Sarasin Holding AG | 0.04% | Add +168.4% | 82,048 | $2.6M |
| Legal & General Group Plc | 0.00% | Add +35.4% | 81,792 | $2.6M |
| Soleus Capital Management, L.P. | 0.17% | New | 78,800 | $2.5M |
| T. Rowe Price Investment Management, Inc. | 0.00% | Reduce -90.3% | 76,943 | $2.4M |
| Nicholas Investment Partners, LP | 0.22% | Reduce -20.8% | 68,896 | $2.2M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -74.2% | 68,869 | $2.2M |
| Raymond James Financial Inc. | 0.00% | Add +2.9% | 65,214 | $2.0M |
| Man Group plc | 0.00% | New | 62,348 | $2.0M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +22.5% | 61,772 | $1.9M |
| California State Teachers Retirement System | 0.00% | Add +8.5% | 60,233 | $1.9M |
| Nebula Research & Development LLC | 0.16% | Add +29.3% | 60,223 | $1.9M |
| Invesco Ltd. | 0.00% | Reduce -71.0% | 59,598 | $1.9M |
| Voya Investment Management LLC | 0.00% | Add +23.7% | 59,465 | $1.9M |
| Baron Capital (BAMCO) | 0.00% | Reduce -44.1% | 56,000 | $1.8M |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.