Xenon PharmaceuticalsXENE
13F holders, Q4 2024 (December 31)209holders +6
23new positions
19sold out
6famous investors
$39.20avg. 13F price*
At the end of Q4 2024, 209 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, up 6 from Q3 2024. 23 opened new positions and 19 sold out. The largest holders were FMR LLC ($295.0M), Avoro Capital Advisors LLC ($222.1M) and Driehaus Capital Management LLC ($177.2M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $62.0M |
| Exits | 19 | $23.6M |
All 13F filers, Q3 2024 → Q4 2024: 5,652,780 shares bought and 4,282,362 shares sold, net +1,370,418 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 209 holders
| FMR LLC | 0.02% | Add +8.8% | 7,525,290 | $295.0M |
| Avoro Capital Advisors LLC | 3.14% | No change | 5,666,666 | $222.1M |
| Driehaus Capital Management LLC | 1.46% | Reduce -1.6% | 4,520,595 | $177.2M |
| Wellington Management Group LLP | 0.03% | Reduce -1.7% | 3,777,611 | $148.1M |
| Braidwell LP | 5.10% | Add +7.6% | 2,913,964 | $114.2M |
| Janus Henderson Group PLC | 0.06% | Add +12.3% | 2,866,755 | $112.4M |
| Commodore Capital LP | 7.87% | Add +1.5% | 2,740,000 | $107.4M |
| Polar Capital Holdings Plc | 0.60% | Add +10.3% | 2,697,657 | $105.7M |
| Capital International Investors | 0.02% | Reduce -1.3% | 2,547,210 | $99.9M |
| Capital World Investors | 0.01% | Reduce -14.4% | 2,294,537 | $89.9M |
| BlackRock, Inc. | 0.00% | Reduce -0.0% | 2,105,236 | $82.5M |
| Adage Capital Partners Gp, L.L.C. | 0.13% | Reduce -10.6% | 1,863,473 | $73.0M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -2.1% | 1,496,511 | $58.7M |
| Alliancebernstein L.P. | 0.02% | Add +1.3% | 1,443,180 | $56.6M |
| T. Rowe Price Investment Management, Inc. | 0.03% | Reduce -4.4% | 1,437,831 | $56.4M |
| JPMorgan Chase & Co. | 0.00% | Add +38.9% | 1,356,895 | $53.2M |
| Rock Springs Capital Management LP | 1.87% | Reduce -4.9% | 1,251,859 | $49.1M |
| Affinity Asset Advisors, LLC | 7.74% | Add +1.5% | 1,161,237 | $45.5M |
| First Light Asset Management, LLC | 4.35% | Reduce -1.8% | 1,160,580 | $45.5M |
| Westfield Capital Management Co. LP | 0.20% | Add +72.8% | 1,157,189 | $45.4M |
| Samlyn Capital, LLC | 0.64% | Reduce -0.2% | 1,017,838 | $39.9M |
| Baker Bros. Advisors LP | 0.42% | No change | 993,679 | $39.0M |
| Orbimed Advisors LLC | 0.77% | Add +4.0% | 947,877 | $37.2M |
| Marshall Wace, LLP | 0.04% | Reduce -24.7% | 899,718 | $35.3M |
| TimesSquare Capital Management, LLC | 0.48% | Add +9.1% | 848,850 | $33.3M |
| Vestal Point Capital, LP | 1.88% | Reduce -1.8% | 810,000 | $31.8M |
| Jennison Associates LLC | 0.02% | Add +39.0% | 801,553 | $31.4M |
| Siren, L.L.C. | 1.29% | No change | 743,769 | $29.2M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -2.8% | 687,145 | $26.9M |
| First Turn Management, LLC | 4.81% | Add +110.6% | 684,986 | $26.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +51.2% | 663,704 | $26.0M |
| Boxer Capital Management, LLC | 2.00% | — | 600,000 | $23.5M |
| Franklin Resources Inc. | 0.01% | Add +1.7% | 575,590 | $22.6M |
| Federated Hermes, Inc. | 0.05% | Reduce -24.1% | 558,500 | $21.9M |
| Fiera Capital Corp | 0.07% | Reduce -3.3% | 535,887 | $21.0M |
| Candriam S.C.A. | 0.11% | Add +6.1% | 492,181 | $19.3M |
| Avidity Partners Management LP | 1.85% | Reduce -42.0% | 474,000 | $18.6M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -10.7% | 410,246 | $16.1M |
| Stempoint Capital LP | 3.70% | New | 375,845 | $14.7M |
| Millennium Management | 0.01% | Add +65.5% | 346,040 | $13.6M |
| Vanguard Group Inc. | 0.00% | Reduce -0.5% | 342,779 | $13.4M |
| Citadel Advisors | 0.01% | Reduce -54.7% | 327,303 | $12.8M |
| Perceptive Advisors LLC | 0.36% | Reduce -38.0% | 325,324 | $12.8M |
| Saturn V Capital Management LP | 4.95% | New | 322,470 | $12.6M |
| Two Sigma Advisers, LP | 0.03% | Add +9.1% | 298,700 | $11.7M |
| Alyeska Investment Group, L.P. | 0.04% | No change | 288,843 | $11.3M |
| State Street Corp. | 0.00% | Add +3.3% | 288,722 | $11.3M |
| Altium Capital Management LLC | 3.52% | Reduce -20.1% | 288,000 | $11.3M |
| Aberdeen Group plc | 0.02% | Add +14.3% | 283,899 | $11.1M |
| DAFNA Capital Management LLC | 2.76% | No change | 273,739 | $10.7M |
| Two Sigma Investments, LP | 0.03% | Add +12.2% | 273,352 | $10.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -13.3% | 259,970 | $10.2M |
| Great Point Partners LLC | 4.53% | New | 245,272 | $9.6M |
| Algert Global LLC | 0.22% | Add +9.9% | 241,417 | $9.5M |
| Assenagon Asset Management S.A. | 0.02% | Add +12.4% | 238,522 | $9.4M |
| Walleye Capital LLC | 0.09% | Add +111.5% | 221,982 | $8.7M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -4.4% | 213,696 | $8.4M |
| Invesco Ltd. | 0.00% | Reduce -2.9% | 209,554 | $8.2M |
| DNB Asset Management AS | 0.03% | Add +6.6% | 203,243 | $8.0M |
| MPM Bioimpact LLC | 1.10% | Add +18.9% | 197,212 | $7.7M |
| Lord, Abbett & Co. LLC | 0.03% | Add +12.1% | 194,971 | $7.6M |
| Parkman Healthcare Partners LLC | 1.01% | Add +0.7% | 193,004 | $7.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +17.9% | 191,852 | $7.5M |
| AXA S.A. | 0.02% | Reduce -0.2% | 187,796 | $7.4M |
| Balyasny Asset Management L.P. | 0.02% | Add +119.2% | 184,580 | $7.2M |
| Granahan Investment Management, LLC | 0.30% | Reduce -9.2% | 182,333 | $7.1M |
| Schroder Investment Management Group | 0.01% | No change | 176,674 | $6.8M |
| Deep Track Capital, LP | 0.25% | New | 169,132 | $6.6M |
| Eversept Partners, LP | 0.63% | New | 155,540 | $6.1M |
| Bridger Management, LLC | 3.09% | No change | 146,800 | $5.8M |
| New York State Common Retirement Fund | 0.01% | No change | 132,521 | $5.2M |
| Ally Bridge Group (NY) LLC | 4.35% | Reduce -39.0% | 129,291 | $5.1M |
| Swiss National Bank | 0.00% | Add +1.0% | 126,600 | $5.0M |
| PFM Health Sciences, LP | 0.36% | Reduce -35.0% | 116,998 | $4.6M |
| Bank of America Corp. | 0.00% | Reduce -16.1% | 106,906 | $4.2M |
| Nan Fung Group Holdings Ltd | 3.58% | No change | 106,680 | $4.2M |
| Baron Capital (BAMCO) | 0.01% | No change | 100,100 | $3.9M |
| State of Wisconsin Investment Board | 0.01% | Reduce -4.4% | 96,584 | $3.8M |
| Neuberger Berman Group LLC | 0.00% | New | 92,961 | $3.6M |
| Ameriprise Financial Inc. | 0.00% | Add +39.1% | 92,350 | $3.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -57.5% | 86,973 | $3.4M |
| Atika Capital Management LLC | 0.37% | Reduce -42.4% | 72,600 | $2.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.1% | 69,529 | $2.7M |
| ExodusPoint Capital Management, LP | 0.03% | Reduce -73.8% | 68,884 | $2.7M |
| Morgan Stanley | 0.00% | Reduce -71.6% | 68,062 | $2.7M |
| HighVista Strategies LLC | 0.97% | Reduce -9.4% | 66,788 | $2.6M |
| Northern Trust Corp. | 0.00% | Add +51.5% | 65,783 | $2.6M |
| Voya Investment Management LLC | 0.00% | Add +32.3% | 62,415 | $2.4M |
| Ikarian Capital, LLC | 0.69% | Reduce -42.1% | 62,052 | $2.4M |
| Alps Advisors Inc. | 0.02% | Add +8.2% | 61,648 | $2.4M |
| Legal & General Group Plc | 0.00% | Add +9.6% | 60,406 | $2.4M |
| Royal Bank of Canada | 0.00% | Add +59.6% | 60,068 | $2.4M |
| Wells Fargo & Company | 0.00% | Reduce -1.6% | 59,520 | $2.3M |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 55,492 | $2.2M |
| Moore Capital Management, LP | 0.04% | No change | 55,000 | $2.2M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +11.2% | 54,033 | $2.1M |
| BIT Capital GmbH | 0.19% | New | 53,928 | $2.1M |
| Deutsche Bank AG | 0.00% | No change | 53,711 | $2.1M |
| Sphera Funds Management LTD. | 0.38% | New | 52,097 | $2.0M |
| ADAR1 Capital Management, LLC | 0.42% | Add +81.2% | 50,547 | $2.0M |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.