Xenon PharmaceuticalsXENE
13F holders, Q1 2025 (March 31)206holders −3
20new positions
22sold out
6famous investors
$33.58avg. 13F price*
At the end of Q1 2025, 206 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, down 3 from Q4 2024. 20 opened new positions and 22 sold out. The largest holders were FMR LLC ($278.0M), Avoro Capital Advisors LLC ($192.6M) and Driehaus Capital Management LLC ($153.8M). 6 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $33.5M |
| Exits | 22 | $26.9M |
All 13F filers, Q4 2024 → Q1 2025: 6,629,185 shares bought and 6,216,567 shares sold, net +412,618 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 206 holders
| FMR LLC | 0.02% | Add +10.1% | 8,287,499 | $278.0M |
| Avoro Capital Advisors LLC | 3.01% | Add +1.3% | 5,741,666 | $192.6M |
| Driehaus Capital Management LLC | 1.48% | Add +1.4% | 4,584,859 | $153.8M |
| Wellington Management Group LLP | 0.02% | Add +0.3% | 3,789,197 | $127.1M |
| Janus Henderson Group PLC | 0.06% | Add +16.0% | 3,325,093 | $113.9M |
| Capital International Investors | 0.02% | Add +21.3% | 3,088,730 | $103.6M |
| Braidwell LP | 4.74% | Reduce -7.0% | 2,709,875 | $90.9M |
| Polar Capital Holdings Plc | 0.54% | Reduce -2.8% | 2,623,039 | $88.0M |
| Commodore Capital LP | 5.75% | Reduce -15.2% | 2,325,000 | $78.0M |
| Capital World Investors | 0.01% | Reduce -3.0% | 2,224,715 | $74.6M |
| BlackRock, Inc. | 0.00% | Reduce -3.3% | 2,036,125 | $68.3M |
| Adage Capital Partners Gp, L.L.C. | 0.12% | Add +2.8% | 1,914,749 | $64.2M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -1.3% | 1,477,617 | $49.6M |
| Westfield Capital Management Co. LP | 0.23% | Add +20.2% | 1,391,370 | $46.7M |
| JPMorgan Chase & Co. | 0.00% | Add +0.1% | 1,357,602 | $45.5M |
| Alliancebernstein L.P. | 0.02% | Reduce -7.9% | 1,329,386 | $44.6M |
| Affinity Asset Advisors, LLC | 7.39% | Add +14.4% | 1,328,175 | $44.6M |
| Vestal Point Capital, LP | 3.11% | Add +60.5% | 1,300,000 | $43.6M |
| Samlyn Capital, LLC | 0.56% | Reduce -0.1% | 1,016,381 | $34.1M |
| Deep Track Capital, LP | 1.09% | Add +491.3% | 1,000,000 | $33.5M |
| Orbimed Advisors LLC | 0.76% | No change | 947,877 | $31.8M |
| Rock Springs Capital Management LP | 1.79% | Reduce -25.6% | 931,681 | $31.3M |
| T. Rowe Price Investment Management, Inc. | 0.02% | Reduce -44.6% | 796,986 | $26.7M |
| Jennison Associates LLC | 0.02% | Reduce -3.1% | 776,693 | $26.1M |
| Marshall Wace, LLP | 0.03% | Reduce -15.7% | 758,145 | $25.4M |
| TimesSquare Capital Management, LLC | 0.40% | Reduce -12.2% | 745,551 | $25.0M |
| Siren, L.L.C. | 1.39% | Reduce -1.5% | 732,761 | $24.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +6.0% | 703,795 | $23.6M |
| Citadel Advisors | 0.02% | Add +109.9% | 687,088 | $23.1M |
| First Turn Management, LLC | 4.62% | Reduce -0.2% | 683,451 | $22.9M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -2.1% | 673,011 | $22.6M |
| Logos Global Management LP | 3.88% | New | 650,000 | $21.8M |
| First Light Asset Management, LLC | 2.41% | Reduce -45.9% | 627,904 | $21.1M |
| Boxer Capital Management, LLC | 6.06% | No change | 600,000 | $20.1M |
| Fiera Capital Corp | 0.06% | Reduce -1.2% | 529,442 | $17.8M |
| Franklin Resources Inc. | 0.00% | Reduce -14.7% | 491,120 | $16.5M |
| Candriam S.C.A. | 0.10% | Reduce -7.6% | 454,650 | $15.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +7.9% | 442,732 | $14.9M |
| Saturn V Capital Management LP | 7.00% | Add +28.3% | 413,711 | $13.9M |
| Aberdeen Group plc | 0.03% | Add +42.4% | 404,154 | $13.6M |
| Alyeska Investment Group, L.P. | 0.05% | Add +27.1% | 367,233 | $12.3M |
| Baker Bros. Advisors LP | 0.13% | Reduce -65.0% | 347,408 | $11.7M |
| Vanguard Group Inc. | 0.00% | Reduce -1.8% | 336,514 | $11.3M |
| Perceptive Advisors LLC | 0.39% | No change | 325,324 | $10.9M |
| State Street Corp. | 0.00% | Add +5.8% | 305,620 | $10.3M |
| MPM Bioimpact LLC | 1.75% | Add +53.8% | 303,398 | $10.2M |
| Two Sigma Advisers, LP | 0.02% | Add +0.0% | 298,800 | $10.0M |
| Stempoint Capital LP | 2.94% | Reduce -26.9% | 274,633 | $9.2M |
| DAFNA Capital Management LLC | 2.64% | No change | 273,739 | $9.2M |
| Balyasny Asset Management L.P. | 0.02% | Add +44.7% | 267,142 | $9.0M |
| Bank of New York Mellon Corp | 0.00% | Add +439.0% | 251,147 | $8.4M |
| Great Point Partners LLC | 4.47% | No change | 245,272 | $8.2M |
| Assenagon Asset Management S.A. | 0.01% | Add +1.1% | 241,206 | $8.1M |
| Two Sigma Investments, LP | 0.02% | Reduce -13.3% | 236,983 | $8.0M |
| Millennium Management | 0.01% | Reduce -32.4% | 234,056 | $7.9M |
| Federated Hermes, Inc. | 0.02% | Reduce -58.4% | 232,500 | $7.8M |
| DNB Asset Management AS | 0.04% | Add +12.9% | 229,482 | $7.7M |
| Avidity Partners Management LP | 1.58% | Reduce -51.7% | 229,000 | $7.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -17.4% | 214,860 | $7.2M |
| Point72 Asset Management | 0.02% | New | 209,759 | $7.0M |
| Invesco Ltd. | 0.00% | Reduce -1.8% | 205,763 | $6.9M |
| Granahan Investment Management, LLC | 0.31% | Add +0.8% | 183,808 | $6.2M |
| AXA S.A. | 0.02% | Reduce -6.6% | 175,350 | $5.9M |
| Parkman Healthcare Partners LLC | 0.69% | Reduce -9.6% | 174,576 | $5.9M |
| Nan Fung Group Holdings Ltd | 4.34% | Add +48.7% | 158,605 | $5.3M |
| Renaissance Technologies | 0.01% | Add +1029.2% | 154,700 | $5.2M |
| D. E. Shaw & Co. | 0.01% | Add +75.0% | 152,188 | $5.1M |
| Bridger Management, LLC | 2.45% | No change | 146,800 | $4.9M |
| New York State Common Retirement Fund | 0.01% | Add +7.4% | 142,372 | $4.8M |
| Schroder Investment Management Group | 0.00% | Reduce -22.3% | 137,221 | $4.7M |
| Bank of America Corp. | 0.00% | Add +27.8% | 136,569 | $4.6M |
| Morgan Stanley | 0.00% | Add +90.3% | 129,491 | $4.3M |
| ADAR1 Capital Management, LLC | 0.85% | Add +152.3% | 127,548 | $4.3M |
| Swiss National Bank | 0.00% | Reduce -0.8% | 125,600 | $4.2M |
| Algert Global LLC | 0.10% | Reduce -48.9% | 123,415 | $4.1M |
| UBS Group AG | 0.00% | Add +1471.0% | 105,333 | $3.5M |
| Ameriprise Financial Inc. | 0.00% | Add +12.2% | 103,624 | $3.5M |
| Baron Capital (BAMCO) | 0.01% | No change | 100,100 | $3.4M |
| State of Wisconsin Investment Board | 0.01% | Add +0.6% | 97,149 | $3.3M |
| PFM Health Sciences, LP | 0.24% | Reduce -21.2% | 92,236 | $3.1M |
| Lord, Abbett & Co. LLC | 0.01% | Reduce -54.9% | 87,981 | $3.0M |
| Nicholas Investment Partners, LP | 0.34% | Add +493.3% | 86,968 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +23.2% | 81,024 | $2.7M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -64.7% | 75,341 | $2.5M |
| Ally Bridge Group (NY) LLC | 2.11% | Reduce -46.2% | 69,603 | $2.3M |
| Geode Capital Management, LLC | 0.00% | Add +0.1% | 69,597 | $2.3M |
| HighVista Strategies LLC | 0.86% | No change | 66,788 | $2.2M |
| Wells Fargo & Company | 0.00% | Add +10.7% | 65,912 | $2.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -66.9% | 63,568 | $2.1M |
| Raymond James Financial Inc. | 0.00% | Add +211.8% | 63,385 | $2.1M |
| Legal & General Group Plc | 0.00% | No change | 60,406 | $2.0M |
| Altium Capital Management LLC | 5.87% | Reduce -79.1% | 60,251 | $2.0M |
| Royal Bank of Canada | 0.00% | Reduce -1.2% | 59,366 | $2.0M |
| Harbor Capital Advisors, Inc. | 0.09% | Add +13.6% | 56,591 | $1.9M |
| California State Teachers Retirement System | 0.00% | No change | 55,492 | $1.9M |
| Alps Advisors Inc. | 0.01% | Reduce -10.3% | 55,332 | $1.9M |
| Moore Capital Management, LP | 0.07% | No change | 55,000 | $1.8M |
| Deutsche Bank AG | 0.00% | No change | 53,711 | $1.8M |
| Erste Asset Management GmbH | 0.02% | No change | 50,000 | $1.7M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -6.7% | 50,417 | $1.7M |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.