InsmedINSM

13F holders, Q4 2024 (December 31)
438holders +24
49new positions
43sold out
8famous investors
$69.04avg. 13F price*

At the end of Q4 2024, 438 institutions reported holding Insmed Inc. (INSM) in their 13F filings, up 24 from Q3 2024. 49 opened new positions and 43 sold out. The largest holders were Vanguard Group Inc. ($1.3B), BlackRock, Inc. ($1.1B) and Darwin Global Management, Ltd. ($894.8M). 8 famous investors held it, including Stanley Druckenmiller (1.2% of Duquesne Family Office's portfolio), George Soros (0.8% of Soros Fund Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Insmed Inc.
CUSIP
457669307
Latest filing quarter
Q2 2026

History

Number of 13F holders

0200400600800 Q1 2024: 288Q1 2024Q2 2024: 378Q2 2024Q3 2024: 414Q3 2024Q4 2024: 438Q4 2024Q1 2025: 441Q1 2025Q2 2025: 516Q2 2025Q3 2025: 566Q3 2025Q4 2025: 678Q4 2025Q1 2026: 675Q1 2026Q2 2026: 667Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions49$192.7M
Exits43$235.3M

All 13F filers, Q3 2024 → Q4 2024: 18,579,689 shares bought and 14,975,395 shares sold, net +3,604,294 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 438 holders

Vanguard Group Inc. 0.02% Add +6.3% 18,218,973 $1.3B
BlackRock, Inc. 0.02% Add +7.1% 16,032,944 $1.1B
Darwin Global Management, Ltd. 84.75% Add +23.5% 12,960,538 $894.8M
T. Rowe Price Associates Inc. 0.10% Add +1.0% 12,704,410 $877.1M
Capital International Investors 0.09% Add +9.1% 7,116,997 $491.4M
State Street Corp. 0.02% Reduce -1.2% 6,106,153 $421.6M
Baker Bros. Advisors LP 3.74% Add +13.4% 5,006,863 $345.7M
FMR LLC 0.02% Reduce -32.5% 4,856,249 $335.3M
Geode Capital Management, LLC 0.02% Add +7.2% 4,087,143 $282.2M
JPMorgan Chase & Co. 0.02% Reduce -0.6% 3,286,248 $226.9M
Artisan Partners Limited Partnership 0.33% Add +8.4% 3,126,339 $215.8M
RTW Investments, LP 3.15% Reduce -7.9% 3,014,558 $208.1M
Ameriprise Financial Inc. 0.05% Add +10.4% 2,850,097 $196.8M
FIL Ltd 0.17% Add +8.1% 2,638,160 $182.1M
William Blair Investment Management, LLC 0.41% Add +0.5% 2,433,443 $168.0M
Alliancebernstein L.P. 0.06% Reduce -3.5% 2,363,561 $163.2M
Macquarie Group Ltd. 0.19% Add +1.2% 2,313,159 $159.7M
Franklin Resources Inc. 0.04% Reduce -20.6% 2,160,103 $149.1M
T. Rowe Price Investment Management, Inc. 0.08% Reduce -12.9% 1,982,707 $136.9M
Pictet Asset Management Holding SA 0.15% Add +5.2% 1,959,718 $135.3M
Clearbridge Investments, LLC 0.11% Add +3.9% 1,878,450 $129.7M
Norges Bank 0.02% Add +10.7% 1,833,810 $126.6M
Principal Financial Group Inc. 0.07% Reduce -2.9% 1,817,643 $125.5M
Northern Trust Corp. 0.02% Add +19.9% 1,750,642 $120.9M
Goldman Sachs Group Inc. 0.02% Add +23.5% 1,720,049 $118.8M
Adage Capital Partners Gp, L.L.C. 0.20% Add +59.6% 1,647,562 $113.7M
Montanova Capital, LLC 4.12% Reduce -1.5% 1,611,561 $111.3M
Palo Alto Investors LP 17.15% Reduce -17.4% 1,603,465 $110.7M
Integral Health Asset Management, LLC 9.46% Add +6.9% 1,550,000 $107.0M
Charles Schwab Investment Management Inc. 0.02% Add +7.1% 1,546,607 $106.8M
Hood River Capital Management LLC 1.56% Add +3.6% 1,525,628 $105.3M
Lord, Abbett & Co. LLC 0.33% Reduce -0.9% 1,457,210 $100.6M
Janus Henderson Group PLC 0.05% Reduce -2.9% 1,445,696 $99.8M
Bank of New York Mellon Corp 0.02% Reduce -2.2% 1,438,466 $99.3M
Morgan Stanley 0.01% Add +2.3% 1,351,365 $93.3M
Nuveen Asset Management, LLC 0.02% Add +19.4% 1,266,630 $87.4M
Loomis Sayles & Co. L P 0.10% Reduce -2.9% 1,174,791 $81.1M
GW&K Investment Management, LLC 0.67% Reduce -1.6% 1,135,393 $78.4M
Bank of America Corp. 0.01% Reduce -4.0% 1,107,666 $76.5M
Eventide Asset Management, LLC 1.38% Add +21.5% 1,100,993 $76.0M
Marshall Wace, LLP 0.09% Add +38.0% 1,064,215 $73.5M
Invesco Ltd. 0.01% Reduce -4.4% 1,016,090 $70.2M
Westfield Capital Management Co. LP 0.28% Add +272.8% 938,551 $64.8M
Alyeska Investment Group, L.P. 0.24% Add +25.2% 935,779 $64.6M
Vestal Point Capital, LP 3.68% Reduce -43.8% 900,000 $62.1M
American Century Companies Inc. 0.03% Add +12.3% 812,780 $56.1M
Jennison Associates LLC 0.03% Add +0.6% 773,813 $53.4M
Wellington Management Group LLP 0.01% Reduce -21.8% 752,226 $51.9M
Polar Capital Holdings Plc 0.28% Add +7.3% 730,000 $50.4M
Novo Holdings A/S 3.03% No change 724,666 $50.0M
Millennium Management 0.04% Add +23.8% 699,006 $48.3M
Holocene Advisors, LP 0.15% New 687,712 $47.5M
Emerald Advisers, LLC 1.83% Reduce -0.8% 684,636 $47.3M
TimesSquare Capital Management, LLC 0.69% Add +41.4% 684,384 $47.2M
Brown Advisory Inc. 0.06% New 662,997 $45.8M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.11% Add +28.6% 654,901 $45.2M
Long Focus Capital Management, LLC 3.44% Add +3.5% 650,800 $44.9M
Cormorant Asset Management, LP 2.46% Add +30.0% 650,000 $44.9M
Summit Partners Public Asset Management, LLC 1.48% Add +10.5% 638,848 $44.1M
Two Sigma Investments, LP 0.10% Reduce -25.9% 593,996 $41.0M
Duquesne Family Office 1.15% Add +2867.3% 593,470 $41.0M
Fiera Capital Corp 0.13% Reduce -1.8% 581,854 $40.2M
Rock Springs Capital Management LP 1.45% Reduce -19.5% 550,000 $38.0M
Voya Investment Management LLC 0.05% Reduce -26.4% 548,867 $37.9M
Ensign Peak Advisors, Inc 0.06% Add +9.3% 529,049 $36.5M
TD Asset Management Inc 0.03% Add +2.7% 526,890 $36.4M
Assenagon Asset Management S.A. 0.07% Reduce -38.7% 525,193 $36.3M
Eagle Health Investments LP 8.69% No change 513,700 $35.5M
D. E. Shaw & Co. 0.04% Add +662.4% 508,787 $35.1M
Deutsche Bank AG 0.01% Add +76.6% 488,966 $33.8M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Add +15.1% 486,847 $33.6M
First Light Asset Management, LLC 3.11% Reduce -31.8% 470,192 $32.5M
Soros Fund Management 0.79% Reduce -4.9% 455,089 $31.4M
Candriam S.C.A. 0.18% Reduce -4.8% 453,520 $31.3M
Logos Global Management LP 3.64% New 450,000 $31.1M
First Turn Management, LLC 5.53% Add +25.4% 446,980 $30.9M
Susquehanna International Group, LLP 0.05% Add +69.9% 444,435 $30.7M
Frontier Capital Management Co. LLC 0.29% Reduce -26.8% 435,006 $30.0M
Allspring Global Investments Holdings, LLC 0.05% Add +8.4% 423,094 $29.6M
Victory Capital Management Inc. 0.03% Reduce -9.9% 410,577 $28.3M
UBS Group AG 0.01% Add +30.9% 405,725 $28.0M
Emerald Mutual Fund Advisers Trust 1.68% Reduce -17.9% 400,624 $27.7M
MPM Bioimpact LLC 3.82% Reduce -36.7% 389,611 $26.9M
Qube Research & Technologies Ltd 0.04% Reduce -20.5% 389,033 $26.9M
Fred Alger Management, LLC 0.13% Reduce -14.8% 385,460 $26.6M
Silverarc Capital Management, LLC 5.75% Add +7.1% 372,230 $25.7M
Raymond James Financial Inc. 0.01% — 363,446 $25.1M
Sei Investments Co. 0.03% Add +8.7% 362,616 $25.0M
Barclays PLC 0.01% Add +6.7% 354,436 $24.5M
Dimensional Fund Advisors LP 0.01% Reduce -4.4% 350,939 $24.2M
B Group, Inc. 14.77% — 350,000 $24.2M
Caption Management, LLC 1.00% Add +253.2% 348,994 $24.1M
C WorldWide Group Holding A/S 0.29% No change 343,110 $23.7M
Octagon Capital Advisors LP 3.90% Reduce -24.0% 332,000 $22.9M
Two Sigma Advisers, LP 0.05% Reduce -16.9% 326,500 $22.5M
Citadel Advisors 0.02% Reduce -3.8% 323,735 $22.4M
Swiss National Bank 0.01% Add +6.2% 321,100 $22.2M
Soleus Capital Management, L.P. 1.67% Add +958.0% 320,272 $22.1M
New York State Common Retirement Fund 0.03% Add +8.5% 317,753 $21.9M
Panagora Asset Management Inc. 0.10% Add +9.2% 317,162 $21.9M
Manufacturers Life Insurance Company, The 0.02% Add +8.7% 313,181 $21.6M
Patient Square Capital LP 7.93% Add +78.9% 307,167 $21.2M
Aberdeen Group plc 0.04% Add +159.5% 289,653 $20.0M
Rhumbline Advisers 0.02% Add +9.6% 288,337 $19.9M
Nwi Management LP 1.52% Add +186.0% 279,000 $19.3M
Susquehanna Fundamental Investments, LLC 0.31% — 270,960 $18.7M
Schroder Investment Management Group 0.02% Add +90.9% 268,063 $18.5M
Jane Street Group, LLC 0.03% Reduce -60.0% 263,721 $18.2M
Bellevue Group AG 0.34% Reduce -50.8% 258,483 $17.8M
Envestnet Asset Management Inc. 0.01% Add +6.3% 256,358 $17.7M
California Public Employees Retirement System 0.01% Reduce -1.0% 256,355 $17.7M
Sofinnova Investments, Inc. 1.30% Reduce -10.5% 256,281 $17.7M
Citigroup Inc. 0.02% Add +104.0% 247,443 $17.1M
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 2.04% New 243,748 $16.8M
Federated Hermes, Inc. 0.04% Add +448.7% 235,836 $16.3M
Avidity Partners Management LP 1.60% Reduce -60.7% 232,800 $16.1M
AXA S.A. 0.05% Reduce -0.2% 226,821 $15.7M
Kingdon Capital Management, L.L.C. 2.65% Reduce -43.8% 225,000 $15.5M
Cutter Capital Management, LP 5.97% Reduce -2.3% 210,884 $14.6M
Hudson Bay Capital Management LP 0.10% Reduce -12.5% 210,000 $14.5M
Granahan Investment Management, LLC 0.60% Reduce -3.7% 209,354 $14.5M
Ra Capital Management, L.P. 0.18% No change 200,000 $13.8M
Peregrine Capital Management LLC 0.40% Add +11.9% 193,479 $13.4M
BNP Paribas Financial Markets 0.01% Reduce -41.0% 187,016 $12.9M
Royal Bank of Canada 0.00% Reduce -8.2% 184,072 $12.7M
Nicholas Investment Partners, LP 1.23% Add +80.7% 182,743 $12.6M
Rafferty Asset Management, LLC 0.04% Reduce -20.2% 180,913 $12.5M
Legal & General Group Plc 0.00% Add +8.8% 176,014 $12.2M
Driehaus Capital Management LLC 0.10% Add +2.3% 171,289 $11.8M
Comerica Bank 0.05% Add +175.0% 170,780 $11.8M
Artia Global Partners LP 4.68% Add +217.2% 167,939 $11.6M
Woodline Partners LP 0.08% Reduce -25.0% 162,230 $11.2M
Wells Fargo & Company 0.00% Add +26.1% 160,709 $11.1M
Samlyn Capital, LLC 0.18% Reduce -24.8% 159,064 $11.0M
California State Teachers Retirement System 0.01% Add +4.5% 153,343 $10.6M
Neuberger Berman Group LLC 0.01% Add +33.4% 149,241 $10.3M
Prudential Financial Inc. 0.01% Add +9.0% 146,722 $10.1M
WCM Investment Management, LLC 0.02% Reduce -2.4% 144,740 $10.0M
Perceptive Advisors LLC 0.28% Reduce -20.0% 144,000 $9.9M
Segall Bryant & Hamill, LLC 0.13% Reduce -1.3% 139,045 $9.6M
Russell Investments Group, Ltd. 0.01% Add +52.3% 132,154 $9.1M
Altium Capital Management LLC 2.84% Add +1.5% 132,000 $9.1M
State of Wisconsin Investment Board 0.02% Add +11.7% 122,111 $8.4M
Senator Investment Group LP 0.24% New 120,000 $8.3M
Ikarian Capital, LLC 2.36% Reduce -22.6% 119,800 $8.3M
Van Eck Associates Corp. 0.01% Reduce -6.1% 119,234 $8.2M
Ally Bridge Group (NY) LLC 6.77% Reduce -24.2% 114,360 $7.9M
EFG Asset Management (North America) Corp. 1.01% Add +111.6% 107,625 $7.4M
Stempoint Capital LP 1.85% New 106,610 $7.4M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.02% Add +10.9% 105,313 $7.3M
Acuta Capital Partners, LLC 7.28% Reduce -2.5% 104,800 $7.2M
J. Goldman & Co LP 0.25% Add +828.0% 104,179 $7.2M
MetLife Investment Management, LLC 0.04% Add +15.4% 103,429 $7.1M
Tang Capital Management LLC 0.46% No change 100,000 $6.9M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% — 98,460 $6.8M
Orbimed Advisors LLC 0.14% New 94,559 $6.5M
Aquatic Capital Management LLC 0.17% Add +296.8% 91,268 $6.3M
Royce & Associates LP 0.06% Reduce -5.3% 90,027 $6.2M
Rice Hall James & Associates, LLC 0.34% Reduce -5.0% 88,860 $6.1M
HAP Trading, LLC 2.02% Add +4.8% 87,533 $6.0M
Corebridge Financial, Inc. 0.03% Add +2.0% 85,719 $5.9M
Axiom Investors LLC 0.04% Reduce -3.8% 83,874 $5.8M
Mutual of America Capital Management LLC 0.06% Reduce -0.1% 77,048 $5.3M
Algert Global LLC 0.12% Reduce -7.0% 75,754 $5.2M
Thornburg Investment Management Inc. 0.07% Reduce -1.5% 74,749 $5.2M
Informed Momentum Co LLC 0.70% Reduce -33.4% 71,964 $5.0M
Allianz Asset Management GmbH 0.01% Reduce -32.1% 71,750 $5.0M
Intech Investment Management LLC 0.05% Add +52.9% 71,227 $4.9M
Parallax Volatility Advisers, L.P. 0.12% Reduce -46.8% 70,537 $4.9M
Springhill Fund Asset Management (HK) Co Ltd 7.79% — 69,500 $4.8M
Essex Investment Management Co. LLC 0.84% Reduce -12.8% 67,330 $4.6M
First Trust Advisors LP 0.00% Reduce -76.3% 66,690 $4.6M
Twin Tree Management, LP 0.11% New 65,147 $4.5M
AQR Capital Management 0.01% Add +2.0% 64,171 $4.4M
State of New Jersey Common Pension Fund D 0.02% Add +7.4% 64,061 $4.4M
Rhenman & Partners Asset Management AB 0.44% Reduce -52.5% 61,500 $4.2M
Global IMC LLC 0.76% Reduce -35.2% 61,489 $4.2M
Baron Capital (BAMCO) 0.01% Add +48.1% 60,000 $4.1M
Harbor Capital Advisors, Inc. 0.18% Add +237.1% 59,600 $4.1M
Balyasny Asset Management L.P. 0.01% Add +183.3% 58,970 $4.1M
Hillsdale Investment Management Inc. 0.20% Add +0.5% 57,000 $3.9M
ProShare Advisors LLC 0.01% Add +43.0% 56,991 $3.9M
Creative Planning 0.00% Add +26.3% 56,710 $3.9M
Oak Ridge Investments LLC 0.31% Reduce -2.9% 56,636 $3.9M
Diadema Partners LP 4.38% — 56,337 $3.9M
Castleark Management LLC 0.13% Add +21.9% 52,780 $3.6M
Affinity Asset Advisors, LLC 0.59% No change 50,000 $3.5M
DekaBank Deutsche Girozentrale 0.01% No change 50,000 $3.4M
Picton Mahoney Asset Management 0.13% Add +7.4% 48,897 $3.4M
Teacher Retirement System of Texas 0.01% Add +24.4% 48,337 $3.3M
Erste Asset Management GmbH 0.04% No change 47,600 $3.3M
Group One Trading LLC 0.11% Reduce -72.0% 47,874 $3.3M
Arizona State Retirement System 0.02% Add +6.1% 47,342 $3.3M
Handelsbanken Fonder AB 0.01% Add +3.9% 45,281 $3.1M
Hennion & Walsh Asset Management, Inc. 0.14% Reduce -49.8% 43,934 $3.0M
PFM Health Sciences, LP 0.24% Reduce -71.2% 43,774 $3.0M
Edgestream Partners, L.P. 0.13% Add +1242.1% 43,619 $3.0M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.01% Add +18.4% 43,476 $3.0M
F/m Investments LLC 0.11% New 42,793 $3.0M
Treasurer of the State of North Carolina 0.01% Reduce -1.7% 41,770 $2.9M
Voloridge Investment Management, LLC 0.01% Reduce -94.7% 39,377 $2.7M
CANADA LIFE ASSURANCE Co 0.00% Add +4.2% 39,379 $2.7M
Lighthouse Investment Partners, LLC 0.10% Reduce -7.1% 39,000 $2.7M
China Universal Asset Management Co., Ltd. 0.24% Add +14.8% 37,934 $2.6M
Bank of Montreal 0.00% Reduce -85.6% 37,753 $2.6M
State Board of Administration of Florida Retirement System 0.00% No change 37,632 $2.6M
Pathstone Holdings, LLC 0.01% Add +4.5% 37,145 $2.6M
Profund Advisors LLC 0.09% Reduce -19.7% 37,085 $2.6M
Legato Capital Management LLC 0.33% Add +2.2% 36,871 $2.5M
Police & Firemen's Retirement System of New Jersey 0.02% — 36,738 $2.5M
Lion Point Capital, LP 13.27% Reduce -29.7% 36,700 $2.5M
Nwam LLC 0.15% New 36,096 $2.5M
Kennedy Capital Management LLC 0.06% Add +197.6% 36,058 $2.5M
Superstring Capital Management LP 2.18% New 35,966 $2.5M
Parkman Healthcare Partners LLC 0.33% Add +0.7% 35,668 $2.5M
Moody Aldrich Partners LLC 0.45% New 35,478 $2.4M
Guggenheim Capital LLC 0.02% Reduce -7.9% 34,342 $2.4M
Boothbay Fund Management, LLC 0.07% Reduce -22.7% 33,805 $2.3M
KLP Kapitalforvaltning As 0.01% — 33,000 $2.3M
LPL Financial LLC 0.00% Add +10.7% 32,757 $2.3M
BI Asset Management Fondsmaeglerselskab A/S 0.02% New 31,390 $2.2M
Mariner, LLC 0.00% Add +23.4% 30,788 $2.1M
Truist Financial Corp. 0.00% Add +3.4% 30,038 $2.1M
ArrowMark Colorado Holdings LLC 0.03% No change 30,000 $2.1M
Man Group plc 0.01% Reduce -95.3% 28,963 $2.0M
Verition Fund Management LLC 0.01% Reduce -62.7% 28,533 $2.0M
Orion Porfolio Solutions, LLC 0.02% Reduce -1.2% 27,762 $1.9M
Orion Portfolio Solutions, LLC 0.02% Reduce -1.2% 27,762 $1.9M
HighVista Strategies LLC 0.71% Reduce -39.2% 27,612 $1.9M
Stifel Financial Corp. 0.00% Reduce -20.6% 26,880 $1.9M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% Add +22.0% 26,615 $1.8M
Assetmark, Inc. 0.00% Add +1.1% 26,344 $1.8M
Readystate Asset Management LP 0.14% Reduce -87.6% 26,190 $1.8M
Renaissance Technologies 0.00% New 25,287 $1.7M
Cinctive Capital Management LP 0.09% Reduce -17.8% 25,252 $1.7M
STRS Ohio 0.01% Add +8.3% 24,900 $1.7M
Compound Planning, Inc. 0.09% Add +6.6% 24,774 $1.7M
MML Investors Services, LLC 0.01% Add +3.4% 22,955 $1.6M
Baird Financial Group, Inc. 0.00% New 22,289 $1.5M
ADAR1 Capital Management, LLC 0.32% Add +504.7% 21,974 $1.5M
Natixis Advisors, LLC 0.00% Add +2.1% 21,325 $1.5M
Dana Investment Advisors, Inc. 0.05% Reduce -1.9% 21,193 $1.5M
Skandinaviska Enskilda Banken AB (publ) 0.01% No change 21,084 $1.5M
HSBC Holdings PLC 0.00% Add +62.5% 21,108 $1.4M
Simplify Asset Management Inc. 0.10% New 20,520 $1.4M
Public Employees Retirement Association of Colorado 0.01% Add +40.5% 19,574 $1.4M
Cerity Partners LLC 0.00% Reduce -14.5% 18,258 $1.3M
Simplex Trading, LLC 0.04% Reduce -68.6% 18,715 $1.3M
Tower Research Capital LLC (TRC) 0.03% Add +706.2% 18,487 $1.3M
New York Life Investment Management LLC 0.01% Reduce -2.6% 17,875 $1.2M
Ameritas Investment Partners, Inc. 0.04% Add +10.2% 17,551 $1.2M
Cibc World Markets Corp. 0.01% New 16,135 $1.1M
Corient Private Wealth LP 0.00% Add +34.1% 14,730 $1.0M
Oppenheimer Asset Management Inc. 0.01% Add +0.2% 14,482 $1000K
Henshaw Capital LLC 0.04% No change 14,435 $997K
Mirae Asset Securities (usa) Inc. 0.04% Reduce -0.0% 13,936 $962K
Persistent Asset Partners Ltd 0.82% — 12,500 $957K
Calamos Advisors LLC 0.01% Reduce -52.7% 13,376 $923K
Polar Asset Management Partners Inc. 0.02% Reduce -77.2% 13,100 $904K
E Fund Management Co., Ltd. 0.04% Reduce -11.6% 12,858 $888K
Xponance LLC 0.01% Add +23.1% 12,689 $876K
Aigen Investment Management, LP 0.15% Add +193.3% 11,936 $824K
Catalyst Funds Management Pty Ltd 0.19% Add +60.7% 11,250 $777K
Yorktown Management & Research Co Inc 0.73% No change 10,970 $757K
Mackenzie Financial Corp. 0.00% Add +12.5% 10,883 $751K
Tema ETFs LLC 0.30% — 10,626 $734K
NEOS Investment Management LLC 0.02% New 10,626 $734K
Shell Asset Management Co. 0.03% Reduce -0.1% 10,556 $729K
B. Metzler seel. Sohn & Co. AG 0.01% No change 10,510 $726K
Cetera Investment Advisers 0.00% Add +15.0% 10,154 $701K
Allostery Investments LP 1.36% — 10,000 $690K
Cantor Fitzgerald, L. P. 0.03% New 10,000 $682K
US Bancorp \de 0.00% Add +20.2% 9,533 $658K
CenterBook Partners LP 0.04% Reduce -88.5% 9,391 $648K
Los Angeles Capital Management LLC 0.00% Reduce -9.6% 9,205 $636K
Avantax Advisory Services, Inc. 0.00% Add +19.9% 8,967 $619K
Beacon Financial Advisory LLC 0.20% Reduce -23.4% 8,940 $617K
PNC Financial Services Group, Inc. 0.00% Add +17.7% 8,887 $614K
Waldron Private Wealth LLC 0.02% New 8,800 $608K
Keybank National Association 0.00% No change 8,781 $606K
O'shaughnessy Asset Management, LLC 0.01% Reduce -15.3% 8,675 $599K
Capital CS Group, LLC 0.78% New 8,488 $586K
Banco BTG Pactual S.A. 0.14% New 8,240 $576K
Schonfeld Strategic Advisors LLC 0.00% Reduce -79.3% 8,260 $570K
Park Avenue Securities LLC 0.01% Add +42.1% 7,955 $549K
Caxton Associates LP 0.02% Reduce -7.2% 7,678 $530K
Freestone Grove Partners LP 0.01% — 7,583 $524K
Sectoral Asset Management Inc. 0.34% Reduce -23.9% 7,371 $509K
KBC Group NV 0.00% Add +59.5% 6,873 $475K
Commerce Bank 0.00% Reduce -1.1% 6,758 $467K
Snowden Capital Advisors LLC 0.01% Add +2.5% 6,602 $456K
Vanguard Personalized Indexing Management, LLC 0.01% Reduce -8.9% 6,504 $449K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +3.0% 6,401 $446K
Envestnet Portfolio Solutions, Inc. 0.00% Add +3.7% 6,314 $436K
Saxon Interests, Inc. 0.19% Reduce -6.9% 6,163 $425K
JGP Global Gestao de Recursos Ltda. 0.96% Reduce -0.1% 6,120 $423K
Pitcairn Co. 0.02% Reduce -1.0% 6,020 $416K
HighMark Wealth Management LLC 0.24% No change 6,010 $415K
Amalgamated Bank 0.00% Add +10.4% 5,879 $406K
Captrust Financial Advisors 0.00% Reduce -10.1% 5,649 $390K
Vise Technologies, Inc. 0.03% Add +6.3% 5,634 $389K
Intrust Bank NA 0.04% Add +12.1% 5,566 $384K
Private Advisor Group, LLC 0.00% Reduce -2.0% 5,543 $383K
QRG Capital Management, Inc. 0.00% Reduce -10.8% 5,540 $382K
Osaic Holdings, Inc. 0.00% Reduce -56.5% 6,767 $367K
Syon Capital LLC 0.03% New 5,276 $364K
Atria Investments, Inc 0.00% Add +5.0% 5,232 $361K
Values First Advisors, Inc. 0.20% Add +4.4% 5,199 $359K
Praxis Investment Management Inc. 0.02% New 5,100 $352K
One68 Global Capital, LLC 0.18% — 5,000 $345K
Jefferies Financial Group Inc. 0.00% Add +914.2% 5,000 $345K
&partners 0.00% Add +0.6% 4,933 $341K
Vident Advisory, LLC 0.01% Add +36.2% 4,937 $341K
SG Americas Securities, LLC 0.00% Reduce -77.4% 4,875 $337K
Virtus Advisers, LLC 0.14% Reduce -9.2% 4,853 $335K
Financial Advocates Investment Management 0.02% New 4,846 $335K
Glenmede Trust Co. NA 0.00% New 4,751 $328K
CIBC Asset Management Inc 0.00% Add +5.6% 4,685 $323K
Tobam 0.10% Reduce -27.0% 4,643 $321K
CI Investments Inc. 0.00% Add +16.8% 4,396 $303K
Sanctuary Advisors, LLC 0.00% Add +13.7% 3,861 $295K
Cresset Asset Management, LLC 0.00% Add +2.4% 4,215 $291K
HighPoint Advisor Group LLC 0.02% New 3,596 $287K
Fourth Dimension Wealth, LLC 0.14% — 4,021 $278K
AlphaCentric Advisors LLC 0.27% Reduce -21.4% 3,930 $271K
GF Fund Management Co. LTD. 0.01% — 3,756 $259K
Lattice Capital Management, LLC 0.21% New 3,700 $255K
OneDigital Investment Advisors LLC 0.00% Add +11.7% 3,553 $245K
Coldstream Capital Management Inc. 0.01% Add +1.8% 3,551 $245K
Meeder Advisory Services, Inc. 0.02% Reduce -2.0% 3,547 $245K
Nisa Investment Advisors, LLC 0.00% Add +5.5% 3,533 $244K
RWC Asset Management LLP 0.01% Add +13.0% 3,485 $241K
Elevation Point Wealth Partners, LLC 0.02% Reduce -3.3% 3,434 $237K
Jump Financial, LLC 0.01% New 3,336 $230K
Abel Hall, LLC 0.15% Add +4.8% 3,333 $230K
Mercer Global Advisors Inc. 0.00% New 3,281 $227K
Bingham Private Wealth, LLC 0.24% — 3,270 $226K
EntryPoint Capital, LLC 0.09% Reduce -41.5% 3,252 $225K
Wealth Enhancement Advisory Services, LLC 0.00% Add +10.5% 3,231 $223K
GTS Securities LLC 0.01% New 3,229 $223K
Principal Securities, Inc. 0.00% Add +55.5% 3,139 $217K
M&T Bank Corp 0.00% Add +5.6% 3,146 $217K
Quarry LP 0.04% Add +25.0% 3,000 $207K
Farallon Capital Management, L.L.C. 0.00% No change 3,000 $207K
Atom Investors LP 0.03% New 2,947 $203K
FNY Investment Advisers, LLC 0.10% New 2,625 $181K
JCIC Asset Management Inc. 0.07% Add +40.7% 2,560 $177K
Avior Wealth Management, LLC 0.01% New 2,278 $157K
Acadian Asset Management LLC 0.00% Reduce -78.8% 2,005 $138K
Parallel Advisors, LLC 0.00% Add +4.0% 1,990 $137K
Bayforest Capital Ltd 0.17% — 1,987 $137K
IFP Advisors, Inc 0.00% Add +2.9% 1,894 $131K
Walleye Trading LLC 0.00% Add +53.2% 1,826 $126K
National Bank of Canada 0.00% Add +9.7% 1,668 $115K
Cwm, LLC 0.00% Add +13.7% 1,648 $114K
State of Wyoming 0.01% Reduce -1.2% 1,539 $106K
Pin Oak Investment Advisors Inc. 0.10% No change 1,454 $106K
Venturi Wealth Management, LLC 0.00% New 1,250 $86K
Northwest & Ethical Investments L.P. 0.00% No change 1,050 $72K
Blue Trust, Inc. 0.00% Reduce -57.6% 831 $57K
Smartleaf Asset Management LLC 0.01% Add +98.1% 830 $57K
First Horizon Advisors, Inc. 0.00% Add +3.5% 710 $49K
Spire Wealth Management 0.00% New 685 $47K
V-Square Quantitative Management LLC 0.01% Add +60.3% 659 $45K
GAMMA Investing LLC 0.00% Add +15.8% 623 $43K
Huntington National Bank 0.00% Reduce -4.1% 606 $42K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% No change 593 $41K
Daiwa Securities Group Inc. 0.00% Reduce -7.1% 590 $41K
CIBC Private Wealth Group LLC 0.00% Add +16.2% 588 $39K
Signaturefd, LLC 0.00% Add +22.4% 542 $37K
Montag A & Associates Inc. 0.00% No change 500 $35K
Federation des caisses Desjardins du Quebec 0.00% No change 500 $35K
Farther Finance Advisors, LLC 0.00% Reduce -6.7% 446 $31K
Clearstead Advisors, LLC 0.00% Reduce -12.0% 418 $29K
Steward Partners Investment Advisory, LLC 0.00% Add +65.2% 413 $29K
Hexagon Capital Partners LLC 0.01% Reduce -5.3% 408 $28K
Elequin Capital, LP 0.00% New 407 $28K
Lindbrook Capital, LLC 0.00% Reduce -4.5% 358 $25K
Bessemer Group Inc. 0.00% Add +11.7% 335 $23K
EverSource Wealth Advisors, LLC 0.00% Add +21.0% 317 $22K
Danske Bank A/S 0.00% Reduce -84.2% 300 $21K
Allworth Financial LP 0.00% Add +282.6% 264 $21K
Private Trust Co. NA 0.00% Reduce -15.6% 184 $13K
UMB Bank, n.a. 0.00% No change 180 $12K
Sterling Capital Management LLC 0.00% Add +11.3% 177 $12K
Asset Dedication, LLC 0.00% No change 171 $12K
Covestor Ltd 0.01% No change 163 $11K
Rothschild Investment LLC 0.00% Add +6.9% 155 $11K
Washington Trust Advisors, Inc. 0.00% No change 149 $10K
AlphaQuest LLC 0.00% Reduce -69.7% 139 $10K
Jones Financial Companies LLLP 0.00% New 136 $9K
Cullen/Frost Bankers, Inc. 0.00% Add +103.0% 134 $9K
MassMutual Private Wealth & Trust, FSB 0.00% Add +582.4% 116 $8K
WPG Advisers, LLC 0.01% — 114 $8K
Versant Capital Management, Inc 0.00% No change 108 $7K
Wilmington Savings Fund Society, FSB 0.00% No change 96 $7K
Trust Co. of Vermont 0.00% No change 95 $7K
Wolff Wiese Magana LLC 0.00% No change 94 $6K
Truvestments Capital LLC 0.00% No change 84 $6K
Johnson Financial Group, Inc. 0.00% Reduce -21.1% 75 $6K
Caitong International Asset Management Co., Ltd 0.00% — 68 $5K
JFS Wealth Advisors, LLC 0.00% No change 68 $5K
Meeder Asset Management Inc. 0.00% Add +12.7% 62 $4K
Hemington Wealth Management 0.00% Add +22.8% 70 $4K
Bellevue Asset Management, LLC 0.00% No change 57 $4K
Cornerstone Planning Group LLC 0.00% Reduce -18.0% 50 $4K
Geneos Wealth Management Inc. 0.00% New 54 $4K
Global Retirement Partners, LLC 0.00% Reduce -52.7% 44 $3K
Sierra Ocean, LLC 0.00% — 42 $3K
R Squared Ltd 0.00% — 40 $3K
Amundi 0.00% New 42 $3K
Northwestern Mutual Wealth Management Co. 0.00% Reduce -30.9% 38 $3K
Aventura Private Wealth, LLC 0.00% — 36 $2K
Brooklyn Investment Group 0.00% New 30 $2K
Bell Investment Advisors, Inc 0.00% No change 27 $2K
Continuum Advisory, LLC 0.00% No change 27 $2K
Park Place Capital Corp 0.00% No change 23 $2K
SBI Securities Co., Ltd. 0.00% — 23 $2K
Aster Capital Management (DIFC) Ltd 0.00% New 20 $1K
Evermay Wealth Management LLC 0.00% No change 20 $1K
DiNuzzo Private Wealth, Inc. 0.00% Reduce -4.8% 20 $1K
Cassady Schiller Wealth Management, LLC 0.00% New 17 $1K
SJS Investment Consulting Inc. 0.00% Reduce -26.1% 17 $1K
Roxbury Financial LLC 0.00% — 15 $1K
Quadrant Capital Group LLC 0.00% No change 15 $1K
Valley National Advisers Inc. 0.00% No change 22 $1K
Physician Wealth Advisors, Inc. 0.00% New 13 $898
Arax Advisory Partners 0.00% Reduce -51.9% 13 $898
Bokf, NA 0.00% Add +57.1% 11 $718
Moisand Fitzgerald Tamayo, LLC 0.00% No change 10 $691
Fortitude Family Office, LLC 0.00% No change 7 $483
Global Financial Private Client, LLC 0.00% New 6 $414
AdvisorNet Financial, Inc 0.00% New 6 $414
Principia Wealth Advisory, LLC 0.00% — 5 $345
Raleigh Capital Management Inc. 0.00% New 4 $276
Parkworth Wealth Management, Inc. 0.00% — 3 $207
Whittier Trust Co. of Nevada Inc. 0.00% New 2 $138
High Note Wealth, LLC 0.00% New 2 $138

"% of holder's portfolio" is INSM's weight in each manager's 13F, not the share of Insmed Inc. the manager owns.