Krystal BiotechKRYS

13F holders, Q4 2024 (December 31)
264holders −19
28new positions
51sold out
5famous investors
$156.69avg. 13F price*

At the end of Q4 2024, 264 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, down 19 from Q3 2024. 28 opened new positions and 51 sold out. The largest holders were FMR LLC ($675.8M), BlackRock, Inc. ($631.9M) and Vanguard Group Inc. ($450.9M). 5 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).

Company
Krystal Biotech Inc.
CUSIP
501147102
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400500 Q1 2024: 234Q1 2024Q2 2024: 245Q2 2024Q3 2024: 283Q3 2024Q4 2024: 264Q4 2024Q1 2025: 299Q1 2025Q2 2025: 275Q2 2025Q3 2025: 284Q3 2025Q4 2025: 334Q4 2025Q1 2026: 368Q1 2026Q2 2026: 422Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions28$25.5M
Exits51$59.0M

All 13F filers, Q3 2024 → Q4 2024: 1,065,195 shares bought and 1,604,382 shares sold, net −539,187 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 264 holders

FMR LLC 0.04% Add +0.5% 4,314,014 $675.8M
BlackRock, Inc. 0.01% Add +1.0% 4,033,872 $631.9M
Vanguard Group Inc. 0.01% Add +1.0% 2,878,451 $450.9M
Avoro Capital Advisors LLC 5.83% Add +0.3% 2,628,822 $411.8M
State Street Corp. 0.01% Reduce -12.0% 1,278,975 $200.4M
Capital World Investors 0.02% Add +0.0% 879,203 $137.7M
Frazier Life Sciences Management, L.P. 5.14% Reduce -20.2% 788,460 $123.5M
Redmile Group, LLC 8.22% Reduce -7.0% 753,175 $118.0M
Geode Capital Management, LLC 0.01% Reduce -0.0% 591,596 $92.7M
Dimensional Fund Advisors LP 0.02% Reduce -1.9% 588,599 $92.2M
Hood River Capital Management LLC 1.19% Add +2.1% 512,726 $80.3M
T. Rowe Price Associates Inc. 0.01% Add +16.3% 509,459 $79.8M
Soleus Capital Management, L.P. 4.25% Add +65.2% 358,379 $56.1M
Nuveen Asset Management, LLC 0.01% Reduce -2.5% 304,115 $47.6M
Jennison Associates LLC 0.03% Reduce -26.0% 303,521 $47.5M
Goldman Sachs Group Inc. 0.01% Reduce -8.0% 277,175 $43.4M
Invesco Ltd. 0.01% Reduce -24.7% 275,195 $43.1M
Northern Trust Corp. 0.01% Add +9.9% 262,263 $41.1M
Morgan Stanley 0.00% Reduce -7.1% 256,275 $40.1M
Charles Schwab Investment Management Inc. 0.01% Add +1.2% 243,170 $38.1M
Woodline Partners LP 0.23% Add +23.0% 221,102 $34.6M
Norges Bank 0.00% Reduce -10.1% 219,528 $34.4M
Lord, Abbett & Co. LLC 0.11% Reduce -24.1% 215,628 $33.8M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Reduce -6.5% 210,202 $32.9M
Braidwell LP 1.40% Add +18.9% 200,500 $31.4M
Franklin Resources Inc. 0.01% Reduce -24.5% 184,027 $28.8M
Baker Bros. Advisors LP 0.29% No change 169,934 $26.6M
Bank of New York Mellon Corp 0.00% Reduce -1.3% 169,346 $26.5M
TimesSquare Capital Management, LLC 0.36% Add +39.1% 158,868 $24.9M
JPMorgan Chase & Co. 0.00% Add +18.7% 151,835 $23.8M
Segall Bryant & Hamill, LLC 0.32% Reduce -5.0% 149,309 $23.4M
Principal Financial Group Inc. 0.01% Add +3.1% 123,453 $19.3M
Driehaus Capital Management LLC 0.16% Reduce -25.5% 121,702 $19.1M
Ameriprise Financial Inc. 0.00% Add +26.4% 113,476 $17.8M
Pictet Asset Management Holding SA 0.02% Reduce -2.8% 112,089 $17.6M
C WorldWide Group Holding A/S 0.20% Reduce -22.1% 105,809 $16.6M
Raymond James Financial Inc. 0.01% — 102,061 $16.0M
UBS Group AG 0.00% Add +175.6% 100,131 $15.7M
Citigroup Inc. 0.01% Add +184.0% 99,633 $15.6M
Eventide Asset Management, LLC 0.27% No change 95,781 $15.0M
S Squared Technology, LLC 6.20% Add +26.6% 95,215 $14.9M
Skandinaviska Enskilda Banken AB (publ) 0.06% Reduce -29.4% 89,047 $14.2M
Handelsbanken Fonder AB 0.05% Reduce -9.9% 85,300 $13.4M
Victory Capital Management Inc. 0.01% Reduce -17.3% 81,328 $12.7M
Decheng Capital LLC 2.58% Add +7.0% 76,772 $12.0M
Bank of America Corp. 0.00% Reduce -27.6% 75,799 $11.9M
Voya Investment Management LLC 0.01% Add +5.8% 74,701 $11.7M
Legal & General Group Plc 0.00% Add +4.8% 69,425 $10.9M
Rhumbline Advisers 0.01% Reduce -1.7% 69,136 $10.8M
Public Sector Pension Investment Board 0.04% Add +17.4% 63,010 $9.9M
Aberdeen Group plc 0.02% Add +32.5% 57,033 $8.9M
Integral Health Asset Management, LLC 0.76% New 55,000 $8.6M
Janney Montgomery Scott LLC 0.02% Add +42.0% 52,592 $8.2M
Barclays PLC 0.00% Reduce -7.3% 52,429 $8.2M
Oberweis Asset Management Inc./ 0.35% No change 46,800 $7.3M
Prudential Financial Inc. 0.01% Add +8.6% 41,193 $6.8M
TD Asset Management Inc 0.01% Add +29.9% 43,480 $6.8M
Corient Private Wealth LP 0.01% Reduce -9.8% 43,009 $6.7M
Swiss National Bank 0.00% Add +8.4% 42,400 $6.6M
Palisades Investment Partners, LLC 2.68% Add +9.3% 40,479 $6.3M
Susquehanna International Group, LLP 0.01% Add +302.6% 38,468 $6.0M
Mutual of America Capital Management LLC 0.06% Reduce -0.1% 36,518 $5.7M
Jane Street Group, LLC 0.01% Add +97.2% 35,855 $5.6M
Manufacturers Life Insurance Company, The 0.00% Add +12.8% 35,206 $5.5M
GW&K Investment Management, LLC 0.05% Reduce -3.0% 34,930 $5.5M
Alliancebernstein L.P. 0.00% Add +4.7% 31,120 $4.9M
Allspring Global Investments Holdings, LLC 0.01% Reduce -73.3% 29,777 $4.7M
Kennedy Capital Management LLC 0.10% Add +433.5% 27,711 $4.3M
Rafferty Asset Management, LLC 0.02% Reduce -40.7% 27,201 $4.3M
CANADA LIFE ASSURANCE Co 0.01% Reduce -0.1% 26,754 $4.2M
Deutsche Bank AG 0.00% Add +62.5% 25,361 $4.0M
Verition Fund Management LLC 0.02% Add +55.6% 24,902 $3.9M
State of Wisconsin Investment Board 0.01% Add +6.2% 24,502 $3.8M
Edgestream Partners, L.P. 0.16% Reduce -26.2% 23,810 $3.7M
Rhenman & Partners Asset Management AB 0.38% Add +39.7% 23,750 $3.7M
Orbimed Advisors LLC 0.08% No change 23,500 $3.7M
New York State Common Retirement Fund 0.00% Reduce -9.6% 23,382 $3.7M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% — 23,197 $3.6M
First Trust Advisors LP 0.00% Reduce -41.2% 23,169 $3.6M
Caption Management, LLC 0.14% New 22,339 $3.5M
HRT Financial LP 0.02% New 22,007 $3.4M
Sei Investments Co. 0.00% Reduce -38.2% 21,164 $3.3M
California State Teachers Retirement System 0.00% Add +5.8% 20,388 $3.2M
Thrivent Financial for Lutherans 0.01% Reduce -1.5% 19,563 $3.1M
Millennium Management 0.00% Reduce -60.2% 18,956 $3.0M
Erste Asset Management GmbH 0.04% No change 18,200 $2.9M
EFG Asset Management (North America) Corp. 0.38% Add +30.9% 17,714 $2.8M
Wells Fargo & Company 0.00% Add +21.3% 16,928 $2.7M
New York State Teachers Retirement System 0.01% No change 15,879 $2.5M
Fiera Capital Corp 0.01% Reduce -3.3% 15,673 $2.5M
DekaBank Deutsche Girozentrale 0.00% No change 15,503 $2.4M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% Reduce -1.2% 15,205 $2.4M
MetLife Investment Management, LLC 0.01% Add +4.8% 14,997 $2.3M
State of Alaska, Department of Revenue 0.03% Reduce -0.0% 14,423 $2.3M
Illinois Municipal Retirement Fund 0.03% Add +11.9% 14,146 $2.2M
Hennion & Walsh Asset Management, Inc. 0.10% Reduce -1.7% 13,678 $2.1M
Corebridge Financial, Inc. 0.01% Reduce -7.2% 13,225 $2.1M
Federated Hermes, Inc. 0.00% Add +1.8% 13,048 $2.0M
Schroder Investment Management Group 0.00% No change 12,607 $2.0M
Louisiana State Employees Retirement System 0.04% No change 12,200 $1.9M
State of New Jersey Common Pension Fund D 0.01% Add +19.3% 11,803 $1.8M
Wellington Management Group LLP 0.00% Reduce -7.7% 11,704 $1.8M
Envestnet Asset Management Inc. 0.00% Add +1.1% 11,630 $1.8M
Redwood Investments, LLC 0.48% Reduce -0.5% 11,343 $1.8M
State of Tennessee, Department of Treasury 0.01% Reduce -2.3% 11,299 $1.8M
Citadel Advisors 0.00% Add +11374.0% 11,015 $1.7M
Renaissance Technologies 0.00% Reduce -24.3% 10,900 $1.7M
Intech Investment Management LLC 0.02% Add +49.1% 10,839 $1.7M
Evolutionary Tree Capital Management, LLC 1.71% Add +17.4% 10,700 $1.7M
Marshall Wace, LLP 0.00% New 10,331 $1.6M
Janus Henderson Group PLC 0.00% Add +16.1% 10,071 $1.6M
Los Angeles Capital Management LLC 0.01% No change 9,884 $1.5M
Yousif Capital Management, LLC 0.02% Reduce -1.7% 9,777 $1.5M
ExodusPoint Capital Management, LP 0.02% New 9,761 $1.5M
Squarepoint Ops LLC 0.00% Reduce -39.1% 9,559 $1.5M
Atle Fund Management AB 0.70% No change 9,202 $1.5M
AQR Capital Management 0.00% Add +11.8% 9,339 $1.5M
Privium Fund Management B.V. 0.33% Add +45.7% 9,250 $1.4M
Zacks Investment Management 0.01% Reduce -3.9% 9,078 $1.4M
Teachers Retirement System of the State of Kentucky 0.01% No change 9,010 $1.4M
Comerica Bank 0.01% Reduce -2.3% 8,890 $1.4M
ProShare Advisors LLC 0.00% Add +28.6% 8,848 $1.4M
Maryland State Retirement & Pension System 0.03% Reduce -0.2% 8,523 $1.3M
Cwm, LLC 0.01% Reduce -41.8% 8,053 $1.3M
Jackson Creek Investment Advisors LLC 0.38% Reduce -2.9% 8,052 $1.3M
BNP Paribas Financial Markets 0.00% Reduce -25.3% 7,789 $1.2M
Perigon Wealth Management, LLC 0.03% Add +1.5% 8,289 $1.2M
Schonfeld Strategic Advisors LLC 0.01% Add +17.9% 7,604 $1.2M
Blair William & Co. 0.00% Add +33.7% 7,443 $1.2M
Amalgamated Bank 0.01% Add +0.0% 7,436 $1.2M
D. E. Shaw & Co. 0.00% Reduce -20.5% 7,427 $1.2M
STRS Ohio 0.00% Add +46.0% 7,300 $1.1M
Quantum Private Wealth, LLC 0.36% No change 7,205 $1.1M
Tower Research Capital LLC (TRC) 0.02% Add +7944.8% 6,999 $1.1M
Aquatic Capital Management LLC 0.03% New 6,901 $1.1M
Ensign Peak Advisors, Inc 0.00% No change 6,569 $1.0M
WINTON GROUP Ltd 0.07% Add +24.1% 6,565 $1.0M
Teacher Retirement System of Texas 0.00% Add +27.3% 6,383 $1.0M
Profund Advisors LLC 0.04% Reduce -36.7% 6,321 $990K
Arizona State Retirement System 0.01% Add +8.5% 6,242 $978K
China Universal Asset Management Co., Ltd. 0.09% Add +10.3% 6,098 $955K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +31.2% 6,054 $948K
Oregon Public Employees Retirement Fund 0.02% Reduce -0.1% 5,975 $936K
State Board of Administration of Florida Retirement System 0.00% Reduce -1.0% 5,807 $910K
Commonwealth of Pennsylvania Public School Empls Retrmt SYS 0.01% Reduce -0.0% 5,403 $846K
Creative Planning 0.00% Reduce -6.0% 5,397 $845K
Police & Firemen's Retirement System of New Jersey 0.01% — 5,283 $828K
Martingale Asset Management L P 0.02% Add +0.0% 5,136 $805K
Nicholas Investment Partners, LP 0.08% Reduce -73.0% 5,086 $797K
Bellevue Group AG 0.02% Add +5.6% 5,047 $791K
Commonwealth Equity Services, LLC 0.00% Add +4.1% 4,866 $762K
Guggenheim Capital LLC 0.01% Add +23.6% 4,862 $762K
Jain Global LLC 0.02% — 4,800 $752K
HSBC Holdings PLC 0.00% Add +195.2% 4,519 $718K
KLP Kapitalforvaltning As 0.00% — 4,300 $674K
CenterBook Partners LP 0.04% New 4,283 $671K
Pathstone Holdings, LLC 0.00% Reduce -15.8% 4,252 $666K
HighVista Strategies LLC 0.25% New 4,217 $661K
Hussman Strategic Advisors, Inc. 0.19% New 4,200 $658K
Allianz Asset Management GmbH 0.00% Add +57.6% 4,102 $643K
Pier 88 Investment Partners LLC 0.72% Add +6.2% 3,750 $587K
Cynosure Group, LLC 0.09% Reduce -9.0% 3,630 $569K
Main Management ETF Advisors, LLC 0.03% Reduce -8.3% 3,560 $558K
Entropy Technologies, LP 0.06% New 3,500 $548K
Gsa Capital Partners LLP 0.04% New 3,464 $543K
Summit Global Investments 0.03% New 3,453 $541K
Mariner, LLC 0.00% Reduce -6.8% 3,375 $529K
Credit Agricole S A 0.00% No change 3,336 $523K
Bank of Montreal 0.00% Add +5.7% 3,325 $521K
Parallel Advisors, LLC 0.01% No change 3,237 $507K
AlphaQuest LLC 0.06% Add +116.0% 3,020 $473K
Vontobel Holding Ltd. 0.00% Reduce -60.3% 2,984 $467K
LPL Financial LLC 0.00% Add +156.8% 2,946 $462K
Confluence Wealth Services, Inc. 0.03% No change 2,920 $453K
Nebula Research & Development LLC 0.05% Reduce -43.3% 2,670 $418K
Ameritas Investment Partners, Inc. 0.01% Add +3.3% 2,595 $407K
Vident Advisory, LLC 0.01% Reduce -3.2% 2,492 $390K
Public Employees Retirement Association of Colorado 0.00% No change 2,363 $370K
Sherbrooke Park Advisers LLC 0.12% Reduce -1.1% 2,353 $369K
Cibc World Markets Corp. 0.00% New 2,321 $364K
Crossmark Global Holdings, Inc. 0.01% Add +5.5% 2,307 $362K
Cetera Investment Advisers 0.00% Add +1.4% 2,176 $341K
Fox Run Management, L.L.C. 0.06% New 2,161 $339K
Ballentine Partners, LLC 0.01% Add +2.7% 2,145 $336K
XTX Topco Ltd 0.03% New 2,102 $329K
Graham Capital Management, L.P. 0.02% Reduce -6.7% 2,082 $326K
Virtus Advisers, LLC 0.13% Add +11.9% 2,016 $316K
Farallon Capital Management, L.L.C. 0.00% No change 2,000 $313K
E Fund Management Co., Ltd. 0.02% Reduce -34.2% 1,934 $303K
Argent Trust Co 0.01% No change 1,899 $297K
Old Mission Capital LLC 0.01% New 1,868 $293K
Xponance LLC 0.00% Add +9.5% 1,785 $280K
PNC Financial Services Group, Inc. 0.00% Add +2.2% 1,680 $263K
Headlands Technologies LLC 0.03% Reduce -76.1% 1,635 $256K
DNB Asset Management AS 0.00% Reduce -33.1% 1,537 $241K
Mackenzie Financial Corp. 0.00% Add +3.1% 1,532 $240K
AlphaCentric Advisors LLC 0.23% New 1,474 $231K
Sound View Wealth Advisors Group, LLC 0.02% Add +18.3% 1,420 $222K
Vanguard Personalized Indexing Management, LLC 0.00% Reduce -9.0% 1,400 $219K
Pacer Advisors, Inc. 0.00% New 1,400 $219K
Brevan Howard Capital Management LP 0.01% Reduce -33.3% 1,396 $219K
Transcend Capital Advisors, LLC 0.02% No change 1,382 $217K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% Reduce -13.3% 1,367 $216K
Certuity, LLC 0.02% New 1,365 $214K
Keybank National Association 0.00% Reduce -20.6% 1,309 $205K
US Bancorp \de 0.00% Add +8.7% 1,027 $161K
Nisa Investment Advisors, LLC 0.00% Add +3.8% 1,008 $158K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.8% 958 $153K
KBC Group NV 0.00% Add +46.3% 939 $147K
Avanza Fonder AB 0.00% — 759 $119K
Covestor Ltd 0.07% Add +972.7% 708 $111K
Royal Bank of Canada 0.00% Reduce -76.1% 664 $104K
GF Fund Management Co. LTD. 0.00% — 604 $95K
Huntington National Bank 0.00% Add +1.1% 579 $91K
Lazard Asset Management LLC 0.00% Reduce -66.0% 476 $74K
Russell Investments Group, Ltd. 0.00% Add +3.5% 445 $70K
Walleye Trading LLC 0.00% New 393 $62K
Osaic Holdings, Inc. 0.00% Add +6.6% 306 $48K
Caldwell Trust Co 0.00% No change 250 $39K
GAMMA Investing LLC 0.00% Reduce -44.0% 241 $38K
Wilmington Savings Fund Society, FSB 0.00% No change 218 $34K
Quadrant Capital Group LLC 0.00% Reduce -62.4% 157 $25K
Key Financial Inc 0.01% No change 151 $24K
Smartleaf Asset Management LLC 0.00% Add +64.3% 138 $22K
Caitong International Asset Management Co., Ltd 0.02% — 135 $21K
MAI Capital Management 0.00% New 134 $21K
SBI Securities Co., Ltd. 0.00% — 119 $19K
Signaturefd, LLC 0.00% Reduce -17.7% 107 $17K
Daiwa Securities Group Inc. 0.00% Reduce -9.5% 95 $15K
Fifth Third Bancorp 0.00% Reduce -29.8% 66 $10K
Lindbrook Capital, LLC 0.00% Reduce -25.6% 58 $9K
Versant Capital Management, Inc 0.00% Reduce -29.3% 53 $8K
Bessemer Group Inc. 0.00% Reduce -25.0% 54 $8K
Federation des caisses Desjardins du Quebec 0.00% No change 50 $8K
Brooklyn Investment Group 0.00% New 36 $6K
UMB Bank, n.a. 0.00% Reduce -39.7% 35 $5K
NewEdge Advisors, LLC 0.00% No change 34 $5K
Cullen/Frost Bankers, Inc. 0.00% Add +14.3% 32 $5K
Bell Investment Advisors, Inc 0.00% Add +47.4% 28 $4K
Meeder Asset Management Inc. 0.00% New 26 $4K
MassMutual Private Wealth & Trust, FSB 0.00% Reduce -10.3% 26 $4K
Avior Wealth Management, LLC 0.00% Reduce -23.5% 26 $4K
Sterling Capital Management LLC 0.00% No change 25 $4K
Clearstead Advisors, LLC 0.00% Reduce -38.5% 24 $4K
EverSource Wealth Advisors, LLC 0.00% Reduce -20.7% 23 $4K
Farther Finance Advisors, LLC 0.00% No change 23 $4K
Rakuten Securities, Inc. 0.00% Add +25.0% 20 $3K
Trust Co. of Vermont 0.00% New 20 $3K
Rothschild Investment LLC 0.00% Reduce -32.0% 17 $3K
Farmers & Merchants Investments Inc. 0.00% No change 15 $2K
Harbour Investments, Inc. 0.00% New 14 $2K
Continuum Advisory, LLC 0.00% Reduce -26.7% 11 $2K
Sound Income Strategies, LLC 0.00% No change 10 $2K
Wolff Wiese Magana LLC 0.00% No change 8 $1K
Principal Securities, Inc. 0.00% New 7 $1K
Allworth Financial LP 0.00% Reduce -14.3% 6 $921
Private Wealth Management Group, LLC 0.00% No change 5 $784
Glen Eagle Advisors, LLC 0.00% No change 5 $783
Riverview Trust Co 0.00% New 3 $470
Parkside Financial Bank & Trust 0.00% Add +50.0% 3 $470
Blue Trust, Inc. 0.00% Reduce -99.5% 3 $470
Abound Wealth Management 0.00% No change 2 $314
JFS Wealth Advisors, LLC 0.00% No change 2 $314
Assetmark, Inc. 0.00% New 1 $157

"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.