Krystal BiotechKRYS

13F holders, Q3 2025 (September 30)
284holders +9
43new positions
30sold out
6famous investors
$176.29avg. 13F price*

At the end of Q3 2025, 284 institutions reported holding Krystal Biotech Inc. (KRYS) in their 13F filings, up 9 from Q2 2025. 43 opened new positions and 30 sold out. The largest holders were FMR LLC ($766.4M), BlackRock, Inc. ($676.8M) and Vanguard Group Inc. ($492.9M). 6 famous investors held it, including Ken Griffin (0.1% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ray Dalio (0.0% of Bridgewater Associates's portfolio).

Company
Krystal Biotech Inc.
CUSIP
501147102
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400500 Q1 2024: 234Q1 2024Q2 2024: 245Q2 2024Q3 2024: 283Q3 2024Q4 2024: 264Q4 2024Q1 2025: 299Q1 2025Q2 2025: 275Q2 2025Q3 2025: 284Q3 2025Q4 2025: 334Q4 2025Q1 2026: 368Q1 2026Q2 2026: 422Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions43$34.8M
Exits30$47.8M

All 13F filers, Q2 2025 → Q3 2025: 2,096,277 shares bought and 1,448,289 shares sold, net +647,988 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 284 holders

FMR LLC 0.04% Add +0.1% 4,341,447 $766.4M
BlackRock, Inc. 0.01% Reduce -0.3% 3,834,128 $676.8M
Vanguard Group Inc. 0.01% Reduce -1.1% 2,792,208 $492.9M
Avoro Capital Advisors LLC 6.34% Add +4.4% 2,777,777 $490.4M
State Street Corp. 0.01% Add +3.0% 1,395,967 $246.4M
Soleus Capital Management, L.P. 9.61% Add +10.4% 1,018,831 $179.9M
Capital World Investors 0.02% Reduce -14.1% 809,240 $142.9M
Frazier Life Sciences Management, L.P. 3.65% No change 688,460 $121.5M
Redmile Group, LLC 11.36% Reduce -0.3% 661,388 $116.8M
Citadel Advisors 0.09% Add +1743.1% 636,988 $112.4M
Geode Capital Management, LLC 0.01% Reduce -1.3% 611,244 $107.9M
Hood River Capital Management LLC 1.27% Add +13.9% 606,946 $107.1M
Dimensional Fund Advisors LP 0.02% Add +5.5% 533,964 $94.3M
Braidwell LP 3.72% Reduce -28.5% 520,401 $91.9M
T. Rowe Price Associates Inc. 0.01% Add +78.7% 467,058 $82.5M
Goldman Sachs Group Inc. 0.01% Reduce -34.3% 348,250 $61.5M
First Trust Advisors LP 0.03% Add +11.7% 248,392 $43.8M
Northern Trust Corp. 0.01% Reduce -1.3% 248,165 $43.8M
Charles Schwab Investment Management Inc. 0.01% Reduce -1.4% 242,863 $42.9M
Morgan Stanley 0.00% Add +0.1% 234,578 $41.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Reduce -13.5% 202,589 $35.8M
Nuveen, LLC 0.01% Add +5.0% 197,378 $34.8M
Pictet Asset Management Holding SA 0.03% Add +50.8% 196,904 $34.8M
Bank of New York Mellon Corp 0.00% Reduce -3.1% 155,553 $27.5M
Woodline Partners LP 0.13% No change 150,616 $26.6M
William Blair Investment Management, LLC 0.07% Add +63.9% 149,302 $26.4M
Millennium Management 0.02% Add +1083.8% 148,713 $26.3M
JPMorgan Chase & Co. 0.00% Add +60.6% 146,354 $25.8M
Principal Financial Group Inc. 0.01% Add +1.4% 142,843 $25.2M
Bank of America Corp. 0.00% Add +13.3% 137,995 $24.4M
UBS Group AG 0.00% Add +33.9% 130,173 $23.0M
Marshall Wace, LLP 0.03% Add +14.8% 128,960 $22.8M
TimesSquare Capital Management, LLC 0.30% Add +3.8% 118,514 $20.9M
S Squared Technology, LLC 7.33% No change 109,215 $19.3M
Orbimed Advisors LLC 0.44% Add +1016.8% 102,745 $18.1M
Public Sector Pension Investment Board 0.07% Add +15.8% 100,431 $17.7M
Voya Investment Management LLC 0.02% Add +46.8% 93,908 $16.6M
C WorldWide Group Holding A/S 0.23% No change 85,809 $15.1M
Segall Bryant & Hamill, LLC 0.20% Reduce -42.6% 85,263 $15.1M
Barclays PLC 0.01% Reduce -18.3% 75,896 $13.4M
Rhumbline Advisers 0.01% Reduce -0.3% 70,552 $12.5M
Readystate Asset Management LP 1.21% Reduce -52.5% 70,349 $12.4M
Invesco Ltd. 0.00% Reduce -5.7% 66,880 $11.8M
Handelsbanken Fonder AB 0.04% No change 66,800 $11.8M
Legal & General Group Plc 0.00% Reduce -3.8% 65,815 $11.6M
Raymond James Financial Inc. 0.00% Reduce -6.4% 64,363 $11.4M
Skandinaviska Enskilda Banken AB (publ) 0.04% No change 59,978 $10.6M
Aberdeen Group plc 0.02% Reduce -45.3% 59,372 $10.5M
Ameriprise Financial Inc. 0.00% Reduce -11.2% 55,792 $9.8M
Victory Capital Management Inc. 0.01% Reduce -31.6% 54,816 $9.7M
Biondo Investment Advisors, LLC 1.15% Add +144.3% 51,885 $9.2M
TD Asset Management Inc 0.01% Add +124.5% 45,080 $8.0M
Swiss National Bank 0.00% Add +1.4% 42,000 $7.4M
Palisades Investment Partners, LLC 2.87% Add +3.0% 41,389 $7.3M
Kennedy Capital Management LLC 0.15% Add +3.0% 39,291 $6.9M
Corient Private Wealth LP 0.01% Reduce -3.5% 39,130 $6.9M
Mutual of America Capital Management LLC 0.07% Reduce -1.1% 37,934 $6.7M
Perceptive Advisors LLC 0.18% New 35,000 $6.2M
Rafferty Asset Management, LLC 0.02% Reduce -0.1% 34,640 $6.1M
Manufacturers Life Insurance Company, The 0.01% Add +39.6% 34,455 $6.1M
Decheng Capital LLC 0.99% Reduce -51.1% 32,300 $5.7M
Verition Fund Management LLC 0.03% Add +18.2% 31,333 $5.5M
Alliancebernstein L.P. 0.00% Reduce -3.9% 29,920 $5.3M
State of Wisconsin Investment Board 0.01% Reduce -18.7% 29,340 $5.2M
EFG Asset Management (North America) Corp. 0.62% Add +18.4% 27,095 $4.8M
New York State Common Retirement Fund 0.01% Add +15.4% 26,994 $4.8M
Russell Investments Group, Ltd. 0.01% Add +156.3% 26,549 $4.7M
Prudential Financial Inc. 0.01% Reduce -2.5% 25,496 $4.5M
Ikarian Capital, LLC 0.87% New 24,421 $4.3M
Federated Hermes, Inc. 0.01% Reduce -43.9% 23,981 $4.2M
Sei Investments Co. 0.00% Add +21.2% 23,393 $4.1M
CANADA LIFE ASSURANCE Co 0.01% Add +2.6% 21,398 $3.8M
Deutsche Bank AG 0.00% Add +11.7% 21,379 $3.8M
California State Teachers Retirement System 0.00% Add +3.8% 20,882 $3.7M
Synovus Financial Corp. 0.04% Reduce -0.6% 20,516 $3.6M
AQR Capital Management 0.00% Add +68.2% 20,133 $3.6M
Franklin Resources Inc. 0.00% Add +7.7% 19,850 $3.5M
Wells Fargo & Company 0.00% Add +18.8% 19,653 $3.5M
Thrivent Financial for Lutherans 0.01% Reduce -0.6% 18,584 $3.3M
ADAR1 Capital Management, LLC 0.33% New 18,523 $3.3M
Erste Asset Management GmbH 0.03% No change 18,200 $3.2M
New York State Teachers Retirement System 0.01% Reduce -0.6% 15,550 $2.7M
DekaBank Deutsche Girozentrale 0.00% No change 15,503 $2.7M
Fiera Capital Corp 0.01% Reduce -2.9% 15,063 $2.7M
Fieldview Capital Management, LLC 0.42% Add +1.1% 14,705 $2.6M
State of New Jersey Common Pension Fund D 0.01% Reduce -2.9% 14,599 $2.6M
MetLife Investment Management, LLC 0.01% Reduce -2.1% 14,430 $2.5M
State of Alaska, Department of Revenue 0.03% Reduce -5.7% 14,274 $2.5M
Illinois Municipal Retirement Fund 0.03% Add +15.7% 14,245 $2.5M
Bridge City Capital, LLC 0.67% New 14,154 $2.5M
Alps Advisors Inc. 0.01% Reduce -23.4% 13,367 $2.4M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -13.0% 13,290 $2.3M
Envestnet Asset Management Inc. 0.00% Reduce -13.3% 13,108 $2.3M
Evolutionary Tree Capital Management, LLC 2.40% Add +1.3% 12,461 $2.2M
Privium Fund Management B.V. 0.39% Add +30.6% 12,170 $2.1M
Torray Investment Partners LLC 0.29% Add +2.8% 11,901 $2.1M
Louisiana State Employees Retirement System 0.04% Reduce -0.8% 11,800 $2.1M
Rhenman & Partners Asset Management AB 0.23% Reduce -7.8% 11,750 $2.1M
Creative Planning 0.00% Add +38.9% 11,609 $2.0M
State of Tennessee, Department of Treasury 0.01% Add +1.5% 11,118 $2.0M
Wellington Management Group LLP 0.00% Add +7.2% 10,881 $1.9M
Acuta Capital Partners, LLC 1.93% New 10,573 $1.9M
GW&K Investment Management, LLC 0.02% Reduce -65.2% 10,492 $1.9M
Schroder Investment Management Group 0.00% Reduce -0.6% 10,170 $1.8M
Main Management ETF Advisors, LLC 0.07% Add +96.4% 10,075 $1.8M
Janus Henderson Group PLC 0.00% No change 10,071 $1.8M
Commonwealth Equity Services, LLC 0.00% Add +21.8% 10,006 $1.8M
Connor, Clark & Lunn Investment Management Ltd. 0.01% New 9,778 $1.7M
Intech Investment Management LLC 0.02% Reduce -11.2% 9,751 $1.7M
Bridgewater Associates 0.01% New 9,723 $1.7M
Citigroup Inc. 0.00% Reduce -81.6% 9,650 $1.7M
BNP Paribas Financial Markets 0.00% Add +27.8% 9,179 $1.6M
Perigon Wealth Management, LLC 0.03% Add +0.3% 8,929 $1.6M
Boothbay Fund Management, LLC 0.04% New 8,889 $1.6M
NFJ Investment Group, LLC 0.05% New 8,612 $1.5M
Profund Advisors LLC 0.05% Add +2.0% 8,330 $1.5M
Yousif Capital Management, LLC 0.02% Reduce -14.4% 8,217 $1.5M
WINTON GROUP Ltd 0.05% New 8,212 $1.4M
Tealwood Asset Management Inc. 0.56% Reduce -3.4% 7,902 $1.4M
Amalgamated Bank 0.01% Add +2.6% 7,416 $1.3M
STRS Ohio 0.00% No change 7,400 $1.3M
Teachers Retirement System of the State of Kentucky 0.01% Reduce -13.3% 7,220 $1.3M
Quantum Private Wealth, LLC 0.37% No change 7,205 $1.3M
Comerica Bank 0.00% Reduce -17.9% 7,151 $1.3M
Police & Firemen's Retirement System of New Jersey 0.01% Add +22.5% 6,859 $1.2M
D. E. Shaw & Co. 0.00% Reduce -41.9% 6,814 $1.2M
Los Angeles Capital Management LLC 0.00% Reduce -74.6% 6,757 $1.2M
Commonwealth of Pennsylvania Public School Empls Retrmt SYS 0.01% Add +0.5% 6,560 $1.2M
Summit Trail Advisors, LLC 0.02% Reduce -0.6% 6,464 $1.1M
Arizona State Retirement System 0.01% Add +1.3% 6,397 $1.1M
Cynosure Group, LLC 0.11% No change 5,918 $1.0M
Dark Forest Capital Management LP 0.04% Add +7.3% 5,903 $1.0M
Oregon Public Employees Retirement Fund 0.01% Add +0.6% 5,839 $1.0M
State Board of Administration of Florida Retirement System 0.00% Reduce -0.4% 5,785 $1.0M
ProShare Advisors LLC 0.00% Reduce -13.7% 5,717 $1.0M
Cookson Peirce & Co. Inc. 0.04% New 5,654 $998K
Teacher Retirement System of Texas 0.00% Reduce -8.7% 5,331 $941K
China Universal Asset Management Co., Ltd. 0.07% Reduce -12.6% 5,073 $896K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +21.6% 5,025 $887K
Tetragon Partners GP Ltd 0.21% New 4,870 $860K
Blair William & Co. 0.00% Reduce -2.1% 4,752 $839K
KLP Kapitalforvaltning As 0.00% Add +9.3% 4,700 $830K
Amundi 0.00% Add +8.8% 4,561 $824K
Mariner, LLC 0.00% Add +8.2% 4,605 $813K
Martingale Asset Management L P 0.02% No change 4,505 $795K
Cetera Investment Advisers 0.00% Add +3.5% 4,498 $794K
Atle Fund Management AB 2.93% Add +109.3% 42,191 $791K
Ensign Peak Advisors, Inc 0.00% Reduce -32.7% 4,419 $780K
Pathstone Holdings, LLC 0.00% Add +10.4% 4,347 $767K
Regal Investment Advisors LLC 0.05% Reduce -2.7% 4,316 $762K
Guggenheim Capital LLC 0.01% Reduce -33.2% 4,052 $715K
OMERS ADMINISTRATION Corp 0.01% New 4,000 $706K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 3,864 $682K
Pier 88 Investment Partners LLC 0.75% No change 3,820 $674K
Susquehanna Portfolio Strategies, LLC 0.01% Add +6.8% 3,779 $667K
Legato Capital Management LLC 0.07% New 3,757 $663K
Maryland State Retirement & Pension System 0.01% Reduce -50.4% 3,705 $654K
CenterBook Partners LP 0.03% Reduce -32.1% 3,429 $605K
Jane Street Group, LLC 0.00% New 3,381 $597K
SG Americas Securities, LLC 0.00% Reduce -73.7% 3,318 $586K
Aviva PLC 0.00% Reduce -9.6% 3,231 $570K
Vontobel Holding Ltd. 0.00% Add +3.4% 3,178 $561K
Virtus Investment Advisers, LLC 0.16% No change 3,167 $559K
Resona Asset Management Co.,Ltd. 0.00% Add +4.8% 3,057 $540K
Confluence Wealth Services, Inc. 0.03% No change 2,922 $516K
Sig Brokerage, LP 0.13% New 2,849 $503K
Optimize Financial Inc. 0.26% New 2,815 $497K
CIBC Bancorp USA Inc. 0.00% — 2,643 $467K
Janney Montgomery Scott LLC 0.00% Add +10.3% 2,580 $455K
Advantage Alpha Capital Partners LP 0.13% Reduce -17.5% 2,387 $421K
Public Employees Retirement Association of Colorado 0.00% No change 2,363 $417K
DNB Asset Management AS 0.00% Add +36.1% 2,356 $416K
Bank of Montreal 0.00% Reduce -47.1% 2,329 $411K
Quantinno Capital Management LP 0.00% New 2,162 $382K
Wolverine Trading, LLC 0.01% New 2,154 $381K
Ballentine Partners, LLC 0.01% No change 2,115 $373K
Man Group plc 0.00% Reduce -93.2% 2,088 $369K
Allspring Global Investments Holdings, LLC 0.00% Reduce -0.9% 2,049 $368K
Ameritas Investment Partners, Inc. 0.01% Reduce -17.4% 2,072 $366K
Crossmark Global Holdings, Inc. 0.01% Reduce -15.8% 2,069 $365K
Freestone Grove Partners LP 0.00% Add +7.2% 2,031 $359K
Vanguard Personalized Indexing Management, LLC 0.00% Add +18.6% 2,011 $355K
Sound View Wealth Advisors Group, LLC 0.02% Add +2.9% 2,003 $354K
Yorktown Management & Research Co Inc 0.28% New 2,000 $353K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% Reduce -74.4% 2,000 $353K
Farallon Capital Management, L.L.C. 0.00% No change 2,000 $353K
Xponance LLC 0.00% Add +1.1% 1,951 $344K
Altfest L J & Co. Inc. 0.04% New 1,870 $330K
Parallel Advisors, LLC 0.01% No change 1,863 $329K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% Add +0.2% 1,798 $317K
Covestor Ltd 0.17% Add +29.5% 1,778 $314K
Campbell & CO Investment Adviser LLC 0.02% Reduce -13.6% 1,721 $304K
City Center Advisors, LLC 0.29% New 1,702 $300K
PNC Financial Services Group, Inc. 0.00% Add +19.1% 1,694 $299K
Transcend Capital Advisors, LLC 0.02% New 1,680 $297K
Mackenzie Financial Corp. 0.00% No change 1,597 $282K
Cwm, LLC 0.00% Reduce -3.0% 1,536 $271K
O'shaughnessy Asset Management, LLC 0.00% New 1,485 $262K
Mindset Wealth Management, LLC 0.07% New 1,470 $259K
Avanza Fonder AB 0.01% Add +50.7% 1,418 $250K
Vident Advisory, LLC 0.00% Reduce -28.5% 1,418 $250K
Bellevue Group AG 0.00% Add +5.0% 1,312 $232K
Gotham Asset Management 0.00% New 1,307 $231K
Argent Trust Co 0.01% New 1,307 $231K
Oppenheimer Asset Management Inc. 0.00% New 1,263 $223K
Hohimer Wealth Management, LLC 0.03% New 1,215 $214K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +0.3% 1,119 $198K
Tower Research Capital LLC (TRC) 0.00% Reduce -66.9% 993 $175K
Nisa Investment Advisors, LLC 0.00% Add +4.5% 926 $163K
Advisory Services Network, LLC 0.00% New 854 $151K
KBC Group NV 0.00% No change 685 $121K
AlphaQuest LLC 0.01% Add +14.7% 664 $117K
GF Fund Management Co. LTD. 0.00% Reduce -15.3% 623 $110K
Pacer Advisors, Inc. 0.00% Add +33.4% 607 $107K
Canada Pension Plan Investment Board 0.00% Reduce -40.0% 600 $106K
GAMMA Investing LLC 0.00% Add +74.4% 497 $88K
Exchange Traded Concepts, LLC 0.00% New 496 $88K
Smartleaf Asset Management LLC 0.00% Add +101.0% 422 $75K
Royal Bank of Canada 0.00% Reduce -78.0% 398 $70K
Abich Financial Wealth Management LLC 0.02% — 395 $70K
Wilmington Savings Fund Society, FSB 0.00% Add +78.6% 393 $69K
Osaic Holdings, Inc. 0.00% Reduce -1.3% 388 $62K
Pilgrim Partners Asia Pte Ltd 0.03% — 330 $58K
US Bancorp \de 0.00% Reduce -38.5% 310 $55K
Hantz Financial Services, Inc. 0.00% Add +61.3% 292 $52K
MAI Capital Management 0.00% Add +79.8% 284 $50K
Arax Advisory Partners 0.00% Add +4166.7% 256 $45K
Caldwell Trust Co 0.00% No change 250 $44K
Danske Bank A/S 0.00% No change 200 $35K
Huntington National Bank 0.00% Reduce -25.8% 190 $34K
Salomon & Ludwin, LLC 0.00% New 182 $33K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% No change 174 $31K
AdvisorNet Financial, Inc 0.00% New 171 $30K
Group One Trading LLC 0.00% New 160 $28K
Key Financial Inc 0.01% No change 151 $27K
Bessemer Group Inc. 0.00% Add +106.9% 149 $26K
Quadrant Capital Group LLC 0.00% New 136 $24K
Fifth Third Bancorp 0.00% Add +45.6% 131 $23K
Natixis 0.00% New 122 $22K
UMB Bank, n.a. 0.00% Add +148.8% 107 $19K
Rockefeller Capital Management L.P. 0.00% New 105 $19K
Reyes Financial Architecture, Inc. 0.01% No change 100 $18K
Daiwa Securities Group Inc. 0.00% Reduce -12.5% 91 $16K
Signaturefd, LLC 0.00% Add +13.9% 90 $16K
IFP Advisors, Inc 0.00% Add +660.0% 76 $13K
MassMutual Private Wealth & Trust, FSB 0.00% Add +20.0% 72 $13K
Versant Capital Management, Inc 0.00% Add +2.9% 71 $13K
SBI Securities Co., Ltd. 0.00% Reduce -2.9% 68 $12K
Rise Advisors, LLC 0.00% No change 66 $12K
EverSource Wealth Advisors, LLC 0.00% Add +103.2% 63 $11K
Sterling Capital Management LLC 0.00% No change 60 $11K
Private Wealth Management Group, LLC 0.00% No change 55 $10K
Federation des caisses Desjardins du Quebec 0.00% No change 50 $9K
Bare Financial Services, Inc 0.00% No change 43 $8K
Jones Financial Companies LLLP 0.00% Add +15.6% 37 $6K
NewEdge Advisors, LLC 0.00% No change 34 $6K
Quent Capital, LLC 0.00% New 34 $6K
Clearstead Advisors, LLC 0.00% Add +37.5% 33 $6K
Farther Finance Advisors, LLC 0.00% Add +37.5% 33 $6K
Rothschild Investment LLC 0.00% Reduce -33.3% 26 $5K
Parkside Financial Bank & Trust 0.00% Add +66.7% 25 $4K
Trust Co. of Vermont 0.00% No change 20 $4K
Allworth Financial LP 0.00% Reduce -54.5% 20 $4K
Global Retirement Partners, LLC 0.00% Add +63.6% 18 $3K
Larson Financial Group LLC 0.00% Add +750.0% 17 $3K
Principal Securities, Inc. 0.00% Add +70.0% 17 $3K
Bell Investment Advisors, Inc 0.00% Reduce -15.8% 16 $3K
Farmers & Merchants Investments Inc. 0.00% No change 15 $3K
Wealthspire Advisors, LLC 0.00% New 15 $3K
Sound Income Strategies, LLC 0.00% No change 10 $2K
JPL Wealth Management, LLC 0.00% New 10 $2K
Salem Investment Counselors Inc. 0.00% New 8 $1K
Blue Trust, Inc. 0.00% No change 6 $1K
Rakuten Securities, Inc. 0.00% No change 5 $883
Clearstead Trust, LLC 0.00% No change 5 $883
Glen Eagle Advisors, LLC 0.00% No change 5 $883
Hughes Financial Services, LLC 0.00% No change 4 $798
Fortitude Family Office, LLC 0.00% No change 4 $706
Essential Partners LLC 0.00% Add +300.0% 4 $706
Retirement Wealth Solutions LLC 0.00% New 2 $354
JFS Wealth Advisors, LLC 0.00% No change 2 $354
Tortoise Investment Management, LLC 0.00% New 1 $177
Abound Wealth Management 0.00% No change 1 $177
Avion Wealth 0.00% No change 4 $0

"% of holder's portfolio" is KRYS's weight in each manager's 13F, not the share of Krystal Biotech Inc. the manager owns.