Protagonist TherapeuticsPTGX
13F holders, Q1 2025 (March 31)275holders +34
69new positions
35sold out
7famous investors
$48.36avg. 13F price*
At the end of Q1 2025, 275 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 34 from Q4 2024. 69 opened new positions and 35 sold out. The largest holders were BlackRock, Inc. ($470.9M), Farallon Capital Management, L.L.C. ($295.3M) and RTW Investments, LP ($276.6M). 7 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 69 | $165.8M |
| Exits | 35 | $133.0M |
All 13F filers, Q4 2024 → Q1 2025: 9,431,521 shares bought and 7,719,420 shares sold, net +1,712,101 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 275 holders
| BlackRock, Inc. | 0.01% | Reduce -1.5% | 9,736,767 | $470.9M |
| Farallon Capital Management, L.L.C. | 1.59% | Add +3.0% | 6,107,006 | $295.3M |
| RTW Investments, LP | 4.23% | Add +4.0% | 5,719,415 | $276.6M |
| Vanguard Group Inc. | 0.00% | Add +1.4% | 4,277,218 | $206.8M |
| Deep Track Capital, LP | 4.70% | Add +200.0% | 3,000,000 | $145.1M |
| State Street Corp. | 0.01% | Reduce -18.8% | 2,706,619 | $130.9M |
| BVF Inc. | 5.08% | Add +35.5% | 2,575,015 | $124.5M |
| Johnson & Johnson | 34.65% | No change | 2,449,183 | $118.4M |
| Geode Capital Management, LLC | 0.01% | Add +3.4% | 1,423,559 | $68.9M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -5.1% | 1,322,006 | $63.9M |
| Perceptive Advisors LLC | 1.87% | Reduce -14.2% | 1,091,271 | $52.8M |
| Wellington Management Group LLP | 0.01% | Add +5.0% | 987,370 | $47.7M |
| ADAR1 Capital Management, LLC | 9.00% | Reduce -7.9% | 939,669 | $45.4M |
| Woodline Partners LP | 0.28% | Add +54.2% | 897,699 | $43.4M |
| Invesco Ltd. | 0.01% | Add +16.3% | 859,648 | $41.6M |
| Lynx1 Capital Management LP | 12.69% | New | 733,014 | $35.4M |
| American Century Companies Inc. | 0.02% | Reduce -26.1% | 685,824 | $33.2M |
| Northern Trust Corp. | 0.00% | Add +1.7% | 639,507 | $30.9M |
| Jefferies Financial Group Inc. | 0.55% | Reduce -57.6% | 631,893 | $30.6M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -3.6% | 557,718 | $27.0M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -26.8% | 555,551 | $26.9M |
| Eversept Partners, LP | 2.99% | Reduce -19.4% | 547,116 | $26.5M |
| 683 Capital Management, LLC | 2.69% | Add +21.9% | 500,000 | $24.2M |
| Morgan Stanley | 0.00% | Reduce -8.0% | 497,105 | $24.0M |
| FMR LLC | 0.00% | Add +8.1% | 478,343 | $23.1M |
| Bank of America Corp. | 0.00% | Add +249.8% | 471,745 | $22.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -18.7% | 468,899 | $22.7M |
| Toronto Dominion Bank | 0.06% | Add +30.6% | 445,440 | $21.5M |
| Focus Partners Wealth | 0.05% | Add +2.2% | 435,097 | $21.0M |
| Affinity Asset Advisors, LLC | 3.21% | Add +207.7% | 400,000 | $19.3M |
| Mangrove Partners Im, LLC | 2.20% | No change | 395,383 | $19.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.05% | Add +201.6% | 379,649 | $18.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.6% | 376,863 | $18.2M |
| UBS Group AG | 0.00% | Add +166.1% | 352,871 | $17.1M |
| Principal Financial Group Inc. | 0.01% | Add +2.8% | 347,095 | $16.8M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | New | 343,504 | $16.6M |
| Qube Research & Technologies Ltd | 0.03% | Add +10.0% | 343,411 | $16.6M |
| Artia Global Partners LP | 4.73% | Add +13.6% | 333,851 | $16.1M |
| Renaissance Technologies | 0.02% | Add +46.3% | 323,567 | $15.6M |
| Raymond James Financial Inc. | 0.01% | Reduce -1.5% | 298,827 | $14.5M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -0.3% | 295,593 | $14.3M |
| Schonfeld Strategic Advisors LLC | 0.09% | New | 287,301 | $13.9M |
| Skandinaviska Enskilda Banken AB (publ) | 0.06% | Reduce -19.9% | 248,950 | $12.0M |
| Driehaus Capital Management LLC | 0.11% | Reduce -30.8% | 235,073 | $11.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -27.5% | 208,756 | $10.1M |
| Burney Co./ | 0.36% | New | 201,985 | $9.8M |
| Jane Street Group, LLC | 0.02% | Add +214.1% | 193,300 | $9.3M |
| Susquehanna International Group, LLP | 0.02% | Add +174.9% | 192,239 | $9.3M |
| Public Sector Pension Investment Board | 0.04% | Add +27.3% | 189,031 | $9.1M |
| Checkpoint Capital L.P. | 4.65% | New | 175,184 | $8.5M |
| TD Asset Management Inc | 0.01% | Reduce -2.2% | 169,932 | $8.2M |
| Soleus Capital Management, L.P. | 0.64% | Reduce -38.5% | 169,000 | $8.2M |
| Jupiter Asset Management Ltd. | 0.08% | New | 168,063 | $8.1M |
| Moody Aldrich Partners LLC | 1.66% | Add +142.5% | 163,483 | $7.9M |
| Rhumbline Advisers | 0.01% | Add +0.1% | 162,065 | $7.8M |
| Citadel Advisors | 0.01% | Reduce -6.1% | 154,067 | $7.5M |
| Nuveen, LLC | 0.00% | — | 152,771 | $7.4M |
| Great Lakes Advisors, LLC | 0.07% | Add +145.9% | 152,318 | $7.4M |
| Panagora Asset Management Inc. | 0.04% | New | 149,908 | $7.2M |
| Legal & General Group Plc | 0.00% | Reduce -2.9% | 148,107 | $7.2M |
| Kennedy Capital Management LLC | 0.16% | Reduce -57.2% | 137,504 | $6.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -3.2% | 136,842 | $6.6M |
| Millennium Management | 0.01% | New | 134,269 | $6.5M |
| Jacobs Levy Equity Management, Inc. | 0.02% | No change | 128,654 | $6.2M |
| Man Group plc | 0.02% | Reduce -18.6% | 128,606 | $6.2M |
| Citigroup Inc. | 0.00% | Add +0.7% | 121,844 | $5.9M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -46.1% | 121,554 | $5.9M |
| Nan Fung Group Holdings Ltd | 4.79% | New | 121,400 | $5.9M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -2.8% | 120,850 | $5.8M |
| Barclays PLC | 0.00% | Reduce -12.1% | 111,432 | $5.4M |
| Opaleye Management Inc. | 1.16% | No change | 105,000 | $5.1M |
| Trexquant Investment LP | 0.06% | Add +12.1% | 103,983 | $5.0M |
| Empowered Funds, LLC | 0.07% | New | 102,532 | $5.0M |
| Victory Capital Management Inc. | 0.01% | Reduce -57.5% | 102,411 | $5.0M |
| Lazard Asset Management LLC | 0.01% | New | 96,420 | $4.7M |
| Swiss National Bank | 0.00% | No change | 86,900 | $4.2M |
| Aquilo Capital Management, LLC | 10.65% | Add +6.7% | 81,692 | $4.0M |
| First Trust Advisors LP | 0.00% | Reduce -42.0% | 81,686 | $4.0M |
| Franklin Resources Inc. | 0.00% | Reduce -11.1% | 79,044 | $3.8M |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 78,894 | $3.8M |
| HighVista Strategies LLC | 1.46% | Add +25.5% | 78,452 | $3.8M |
| Knott David M Jr | 1.73% | Add +45.1% | 76,000 | $3.7M |
| EFG Asset Management (North America) Corp. | 0.57% | New | 71,134 | $3.4M |
| Global IMC LLC | 0.92% | New | 69,750 | $3.4M |
| HRT Financial LP | 0.02% | Add +762.8% | 69,242 | $3.3M |
| Informed Momentum Co LLC | 0.58% | New | 69,181 | $3.3M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.5% | 67,900 | $3.3M |
| Deutsche Bank AG | 0.00% | Reduce -52.4% | 65,695 | $3.2M |
| J. Goldman & Co LP | 0.11% | New | 65,244 | $3.2M |
| Voya Investment Management LLC | 0.00% | Reduce -27.8% | 59,678 | $2.9M |
| Trek Financial, LLC | 0.20% | New | 58,413 | $2.8M |
| Prudential Financial Inc. | 0.00% | Reduce -2.7% | 58,358 | $2.8M |
| Jump Financial, LLC | 0.04% | New | 56,780 | $2.7M |
| Silvercrest Asset Management Group LLC | 0.02% | Reduce -35.2% | 54,723 | $2.6M |
| State of Wisconsin Investment Board | 0.01% | Add +5.8% | 53,740 | $2.6M |
| State of New Jersey Common Pension Fund D | 0.01% | New | 53,736 | $2.6M |
| Alps Advisors Inc. | 0.01% | Reduce -5.3% | 52,974 | $2.6M |
| Hussman Strategic Advisors, Inc. | 0.62% | Reduce -50.0% | 52,500 | $2.5M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -9.9% | 50,955 | $2.5M |
| Stempoint Capital LP | 0.76% | Reduce -65.3% | 49,241 | $2.4M |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.