Protagonist TherapeuticsPTGX
13F holders, Q2 2025 (June 30)273holders −2
50new positions
47sold out
5famous investors
$55.29avg. 13F price*
At the end of Q2 2025, 273 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, down 2 from Q1 2025. 50 opened new positions and 47 sold out. The largest holders were BlackRock, Inc. ($532.3M), Farallon Capital Management, L.L.C. ($341.1M) and RTW Investments, LP ($318.1M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Joel Greenblatt (0.0% of Gotham Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 50 | $141.9M |
| Exits | 47 | $89.7M |
All 13F filers, Q1 2025 → Q2 2025: 11,336,027 shares bought and 5,263,035 shares sold, net +6,072,992 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 273 holders
| BlackRock, Inc. | 0.01% | Reduce -1.1% | 9,630,341 | $532.3M |
| Farallon Capital Management, L.L.C. | 1.56% | Add +1.1% | 6,172,006 | $341.1M |
| RTW Investments, LP | 4.53% | Add +0.6% | 5,756,277 | $318.1M |
| Vanguard Group Inc. | 0.00% | Add +1.9% | 4,358,595 | $240.9M |
| Deep Track Capital, LP | 5.77% | Add +8.2% | 3,245,899 | $179.4M |
| BVF Inc. | 6.34% | Add +24.7% | 3,211,041 | $177.5M |
| State Street Corp. | 0.01% | Add +18.5% | 3,207,543 | $177.3M |
| UBS Group AG | 0.03% | Add +608.8% | 2,501,251 | $138.2M |
| Johnson & Johnson | 40.83% | No change | 2,449,183 | $136.4M |
| Geode Capital Management, LLC | 0.01% | Add +1.4% | 1,444,230 | $79.8M |
| Adage Capital Partners Gp, L.L.C. | 0.10% | Add +218.0% | 1,092,262 | $60.4M |
| Commodore Capital LP | 4.19% | New | 1,075,000 | $59.4M |
| Perceptive Advisors LLC | 2.23% | Reduce -1.5% | 1,074,448 | $59.4M |
| Wellington Management Group LLP | 0.01% | Add +5.1% | 1,037,738 | $57.4M |
| ADAR1 Capital Management, LLC | 8.60% | Add +0.9% | 948,069 | $52.4M |
| Woodline Partners LP | 0.28% | Add +5.5% | 946,884 | $52.3M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -29.1% | 936,703 | $51.8M |
| Morgan Stanley | 0.00% | Add +74.8% | 868,963 | $48.0M |
| Bank of America Corp. | 0.00% | Add +80.6% | 851,832 | $47.1M |
| Jefferies Financial Group Inc. | 0.79% | Add +30.4% | 824,019 | $45.5M |
| American Century Companies Inc. | 0.02% | Add +18.7% | 813,995 | $45.0M |
| Goldman Sachs Group Inc. | 0.01% | Add +39.9% | 777,307 | $43.0M |
| Driehaus Capital Management LLC | 0.34% | Add +222.3% | 757,710 | $41.9M |
| Pictet Asset Management Holding SA | 0.04% | Add +154.4% | 751,977 | $41.6M |
| Lynx1 Capital Management LP | 11.70% | No change | 733,014 | $40.5M |
| Invesco Ltd. | 0.01% | Reduce -16.1% | 721,680 | $39.9M |
| Northern Trust Corp. | 0.00% | Reduce -3.8% | 615,066 | $34.0M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.2% | 575,364 | $31.8M |
| FMR LLC | 0.00% | Add +12.6% | 538,432 | $29.8M |
| Holocene Advisors, LP | 0.07% | New | 530,326 | $29.3M |
| Janus Henderson Group PLC | 0.01% | Add +1982.7% | 446,828 | $24.7M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +17.5% | 446,026 | $24.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.0% | 445,692 | $24.6M |
| Toronto Dominion Bank | 0.05% | No change | 445,440 | $24.6M |
| 683 Capital Management, LLC | 2.64% | Reduce -11.0% | 445,000 | $24.6M |
| Affinity Asset Advisors, LLC | 3.75% | Add +10.0% | 440,000 | $24.3M |
| Jupiter Asset Management Ltd. | 0.19% | Add +141.4% | 405,644 | $22.4M |
| Mangrove Partners Im, LLC | 2.39% | No change | 395,383 | $21.9M |
| Bank of New York Mellon Corp | 0.00% | Add +3.0% | 388,082 | $21.4M |
| Principal Financial Group Inc. | 0.01% | Reduce -4.9% | 330,134 | $18.2M |
| Raymond James Financial Inc. | 0.01% | Add +4.4% | 311,986 | $17.2M |
| Voya Investment Management LLC | 0.02% | Add +369.8% | 280,354 | $15.5M |
| Eversept Partners, LP | 1.54% | Reduce -49.3% | 277,316 | $15.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +16.6% | 243,373 | $13.5M |
| Barclays PLC | 0.00% | Add +90.3% | 212,112 | $11.7M |
| Public Sector Pension Investment Board | 0.05% | Add +11.8% | 211,281 | $11.7M |
| Dimensional Fund Advisors LP | 0.00% | Add +48.1% | 180,050 | $10.0M |
| Renaissance Technologies | 0.01% | Reduce -46.5% | 173,134 | $9.6M |
| Rhumbline Advisers | 0.01% | Add +6.8% | 173,028 | $9.6M |
| Moody Aldrich Partners LLC | 1.82% | Add +4.3% | 170,570 | $9.4M |
| Ameriprise Financial Inc. | 0.00% | Add +23.0% | 168,371 | $9.3M |
| Legal & General Group Plc | 0.00% | Add +12.2% | 166,181 | $9.2M |
| Panagora Asset Management Inc. | 0.04% | Reduce -0.8% | 148,790 | $8.2M |
| Great Lakes Advisors, LLC | 0.06% | Reduce -8.5% | 139,391 | $7.7M |
| Nan Fung Trinity (hk) Ltd. | 0.89% | New | 135,050 | $7.5M |
| Kennedy Capital Management LLC | 0.18% | Reduce -1.9% | 134,890 | $7.5M |
| Nuveen, LLC | 0.00% | Reduce -15.2% | 129,511 | $7.2M |
| Segall Bryant & Hamill, LLC | 0.09% | New | 120,159 | $6.6M |
| TD Asset Management Inc | 0.01% | Reduce -31.5% | 116,332 | $6.4M |
| Capitolis Liquid Global Markets LLC | 0.05% | New | 116,100 | $6.4M |
| First Trust Advisors LP | 0.01% | Add +39.4% | 113,907 | $6.3M |
| Deutsche Bank AG | 0.00% | Add +69.2% | 111,164 | $6.1M |
| Opaleye Management Inc. | 1.20% | No change | 105,000 | $5.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -21.6% | 94,801 | $5.2M |
| Swiss National Bank | 0.00% | Add +7.9% | 93,800 | $5.2M |
| Neuberger Berman Group LLC | 0.00% | New | 93,582 | $5.2M |
| Assenagon Asset Management S.A. | 0.01% | Add +104.8% | 91,875 | $5.1M |
| Victory Capital Management Inc. | 0.00% | Reduce -11.2% | 90,932 | $5.0M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | Reduce -66.8% | 82,750 | $4.6M |
| Franklin Resources Inc. | 0.00% | Add +4.5% | 82,579 | $4.6M |
| EFG Asset Management (North America) Corp. | 0.64% | Add +14.9% | 81,726 | $4.5M |
| Checkpoint Capital L.P. | 2.09% | Reduce -53.6% | 81,311 | $4.5M |
| Rafferty Asset Management, LLC | 0.01% | Add +82.0% | 80,543 | $4.5M |
| Knott David M Jr | 2.00% | Add +5.3% | 80,000 | $4.4M |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 78,894 | $4.4M |
| Citigroup Inc. | 0.00% | Reduce -36.0% | 77,951 | $4.3M |
| Prudential Financial Inc. | 0.01% | Add +32.6% | 77,408 | $4.3M |
| Schonfeld Strategic Advisors LLC | 0.03% | Reduce -73.2% | 77,068 | $4.3M |
| Diadema Partners LP | 2.62% | New | 76,185 | $4.2M |
| Royal Bank of Canada | 0.00% | Add +650.0% | 74,734 | $4.1M |
| Informed Momentum Co LLC | 0.60% | Add +4.0% | 71,971 | $4.0M |
| Susquehanna International Group, LLP | 0.01% | Reduce -62.9% | 71,241 | $3.9M |
| Global IMC LLC | 1.00% | Reduce -0.0% | 69,726 | $3.9M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -79.9% | 68,983 | $3.8M |
| Alliancebernstein L.P. | 0.00% | No change | 67,900 | $3.8M |
| Parkman Healthcare Partners LLC | 0.39% | New | 61,596 | $3.4M |
| Boxer Capital Management, LLC | 1.67% | New | 60,000 | $3.3M |
| HighVista Strategies LLC | 1.18% | Reduce -26.3% | 57,851 | $3.2M |
| New York State Teachers Retirement System | 0.01% | Add +18.9% | 55,713 | $3.1M |
| Silvercrest Asset Management Group LLC | 0.02% | No change | 54,723 | $3.0M |
| Axiom Investors LLC | 0.02% | Add +28.2% | 51,233 | $2.8M |
| California State Teachers Retirement System | 0.00% | Add +22.3% | 51,195 | $2.8M |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -1.4% | 50,242 | $2.8M |
| Capital Fund Management S.A. | 0.03% | New | 49,805 | $2.8M |
| Birchview Capital, LP | 2.63% | Reduce 0.0% | 48,000 | $2.7M |
| Exchange Traded Concepts, LLC | 0.03% | Add +73.0% | 47,391 | $2.6M |
| Thrivent Financial for Lutherans | 0.01% | Add +4.1% | 45,576 | $2.5M |
| Sei Investments Co. | 0.00% | Add +19.7% | 44,932 | $2.5M |
| Natixis | 0.01% | New | 42,040 | $2.3M |
| Aquatic Capital Management LLC | 0.05% | Add +178.0% | 42,000 | $2.3M |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.