Protagonist TherapeuticsPTGX
13F holders, Q1 2026 (March 31)320holders +4
50new positions
49sold out
7famous investors
$105.36avg. 13F price*
At the end of Q1 2026, 320 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 4 from Q4 2025. 50 opened new positions and 49 sold out. The largest holders were BlackRock, Inc. ($1.0B), Farallon Capital Management, L.L.C. ($669.2M) and UBS Group AG ($545.7M). 7 famous investors held it, including Stanley Druckenmiller (0.6% of Duquesne Family Office's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 50 | $221.9M |
| Exits | 49 | $157.7M |
All 13F filers, Q4 2025 → Q1 2026: 10,471,139 shares bought and 4,306,604 shares sold, net +6,164,535 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 320 holders
| BlackRock, Inc. | 0.02% | Add +0.7% | 9,779,369 | $1.0B |
| Farallon Capital Management, L.L.C. | 3.99% | Add +3.3% | 6,348,906 | $669.2M |
| UBS Group AG | 0.10% | Add +86.9% | 5,177,796 | $545.7M |
| RTW Investments, LP | 5.31% | No change | 5,059,053 | $533.2M |
| Wellington Management Group LLP | 0.07% | Add +13.5% | 3,599,644 | $379.4M |
| Vanguard Portfolio Management LLC | 0.02% | — | 3,481,211 | $366.9M |
| State Street Corp. | 0.01% | Reduce -2.6% | 3,116,749 | $328.5M |
| Janus Henderson Group PLC | 0.15% | Add +9.1% | 2,891,527 | $304.9M |
| Vanguard Capital Management LLC | 0.01% | — | 2,805,896 | $295.7M |
| Johnson & Johnson | 39.57% | No change | 2,449,183 | $258.1M |
| Invesco Ltd. | 0.02% | Add +38.1% | 2,164,670 | $228.2M |
| Geode Capital Management, LLC | 0.01% | Add +14.9% | 1,669,371 | $176.0M |
| T. Rowe Price Associates Inc. | 0.02% | Add +18.9% | 1,665,497 | $175.5M |
| Citadel Advisors | 0.12% | Add +37.7% | 1,551,900 | $163.6M |
| Woodline Partners LP | 0.56% | Add +0.4% | 1,414,173 | $149.1M |
| Bank of America Corp. | 0.01% | Add +49.3% | 1,295,434 | $136.5M |
| Perceptive Advisors LLC | 2.57% | Reduce -8.8% | 1,230,879 | $129.7M |
| Jennison Associates LLC | 0.08% | Add +223.7% | 1,072,011 | $113.0M |
| Morgan Stanley | 0.01% | Add +15.8% | 1,018,222 | $107.3M |
| ADAR1 Capital Management, LLC | 6.35% | Reduce -5.3% | 994,119 | $104.8M |
| Hood River Capital Management LLC | 0.88% | New | 829,285 | $87.4M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -19.0% | 778,945 | $82.1M |
| Driehaus Capital Management LLC | 0.56% | Reduce -34.4% | 720,928 | $76.0M |
| FMR LLC | 0.00% | Add +22.6% | 661,997 | $69.8M |
| Marshall Wace, LLP | 0.07% | Reduce -38.7% | 628,075 | $66.2M |
| Clearbridge Investments, LLC | 0.06% | Add +26.9% | 621,820 | $65.5M |
| Alyeska Investment Group, L.P. | 0.18% | Add +197.3% | 593,197 | $62.5M |
| Northern Trust Corp. | 0.01% | Add +2.2% | 587,968 | $62.0M |
| Pictet Asset Management Holding SA | 0.06% | Add +9.7% | 581,083 | $61.2M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 5.11% | No change | 571,825 | $60.3M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -0.7% | 552,956 | $58.3M |
| American Century Companies Inc. | 0.03% | Add +0.3% | 537,320 | $56.6M |
| Dimensional Fund Advisors LP | 0.01% | Add +22.6% | 508,103 | $53.5M |
| Voya Investment Management LLC | 0.06% | Add +24.1% | 454,383 | $47.9M |
| Rubric Capital Management LP | 0.55% | New | 427,998 | $45.1M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 412,730 | $43.5M |
| Principal Financial Group Inc. | 0.02% | Add +5.7% | 367,822 | $38.8M |
| 683 Capital Management, LLC | 3.66% | Reduce -6.7% | 355,000 | $37.4M |
| Bank of New York Mellon Corp | 0.01% | Reduce -2.5% | 341,465 | $36.0M |
| Vestal Point Capital, LP | 0.96% | New | 326,159 | $34.4M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Reduce -7.5% | 306,037 | $32.3M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | Add +21.3% | 282,436 | $29.8M |
| SEB Asset Management AB | 0.10% | — | 232,416 | $24.5M |
| NEXTBio Capital Management LP | 11.24% | No change | 229,619 | $24.2M |
| Segall Bryant & Hamill, LLC | 0.32% | Add +64.8% | 212,714 | $22.4M |
| Public Sector Pension Investment Board | 0.07% | Add +3.4% | 210,280 | $22.2M |
| Holocene Advisors, LP | 0.05% | Reduce -0.1% | 209,916 | $22.1M |
| BNP Paribas Financial Markets | 0.01% | Add +99.0% | 194,530 | $20.5M |
| TD Asset Management Inc | 0.02% | Add +15.7% | 183,700 | $19.4M |
| Eagle Health Investments LP | 3.97% | Add +212.9% | 179,322 | $18.9M |
| Fisher Asset Management | 0.01% | Add +167.2% | 173,971 | $18.3M |
| Affinity Asset Advisors, LLC | 1.09% | No change | 172,125 | $18.1M |
| Boxer Capital Management, LLC | 2.35% | No change | 170,000 | $17.9M |
| Raymond James Financial Inc. | 0.01% | Reduce -2.3% | 177,361 | $17.8M |
| Susquehanna International Group, LLP | 0.02% | Add +1324.7% | 167,576 | $17.7M |
| JPMorgan Chase & Co. | 0.00% | Add +11.4% | 172,990 | $17.3M |
| Lord, Abbett & Co. LLC | 0.06% | New | 163,459 | $17.2M |
| Nan Fung Trinity (hk) Ltd. | 1.86% | Reduce -11.1% | 160,670 | $16.9M |
| Duquesne Family Office | 0.57% | No change | 159,700 | $16.8M |
| Citigroup Inc. | 0.01% | Add +67.2% | 158,711 | $16.7M |
| Rhumbline Advisers | 0.01% | Add +1.6% | 157,413 | $16.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -14.1% | 145,690 | $15.4M |
| Neuberger Berman Group LLC | 0.01% | Add +43.6% | 141,441 | $14.9M |
| Franklin Resources Inc. | 0.00% | Add +80.4% | 137,871 | $14.5M |
| Kennedy Capital Management LLC | 0.31% | Reduce -38.1% | 137,099 | $14.5M |
| Legal & General Group Plc | 0.00% | Reduce -9.3% | 135,367 | $14.3M |
| Nuveen, LLC | 0.00% | Add +1.6% | 127,914 | $13.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.8% | 127,818 | $13.5M |
| Deutsche Bank AG | 0.00% | Add +19.0% | 125,451 | $13.2M |
| Panagora Asset Management Inc. | 0.05% | Reduce -7.0% | 116,609 | $12.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.8% | 107,437 | $11.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Reduce -7.5% | 105,514 | $11.1M |
| Balyasny Asset Management L.P. | 0.02% | New | 101,299 | $10.7M |
| Opaleye Management Inc. | 1.39% | Reduce -4.8% | 100,000 | $10.5M |
| Swiss National Bank | 0.01% | Add +0.7% | 98,900 | $10.4M |
| Prudential Financial Inc. | 0.01% | Reduce -13.7% | 95,235 | $10.0M |
| First Trust Advisors LP | 0.01% | Add +89.1% | 87,858 | $9.3M |
| Axiom Investors LLC | 0.10% | Reduce -4.5% | 85,475 | $9.0M |
| Victory Capital Management Inc. | 0.01% | Add +3.7% | 83,544 | $8.8M |
| Sei Investments Co. | 0.01% | Add +122.8% | 83,197 | $8.8M |
| Algert Global LLC | 0.12% | Add +1441.7% | 78,470 | $8.3M |
| Stempoint Capital LP | 1.47% | Add +22.1% | 72,577 | $7.6M |
| Great Lakes Advisors, LLC | 0.06% | Reduce -4.0% | 71,043 | $7.5M |
| Knott David M Jr | 3.95% | Reduce -13.7% | 63,000 | $6.6M |
| Atika Capital Management LLC | 1.03% | Reduce -27.8% | 62,100 | $6.5M |
| Alliancebernstein L.P. | 0.00% | Add +0.8% | 73,790 | $6.4M |
| California State Teachers Retirement System | 0.01% | Add +22.2% | 58,677 | $6.2M |
| Bessemer Group Inc. | 0.01% | Add +0.0% | 54,178 | $5.7M |
| Moody Aldrich Partners LLC | 1.02% | Reduce -33.1% | 53,893 | $5.7M |
| KVP Capital Advisors, LP | 4.17% | No change | 53,000 | $5.6M |
| Nordea Investment Management AB | 0.01% | New | 51,821 | $5.3M |
| EFG International AG | 0.11% | Reduce -31.0% | 50,086 | $5.3M |
| Integral Health Asset Management, LLC | 0.28% | New | 50,000 | $5.3M |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +0.3% | 49,020 | $5.2M |
| Creative Planning | 0.00% | Add +16.3% | 47,971 | $5.1M |
| Silvercrest Asset Management Group LLC | 0.04% | Reduce -9.9% | 47,931 | $5.1M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -4.4% | 47,440 | $5.0M |
| New York State Teachers Retirement System | 0.01% | Reduce -3.9% | 47,424 | $5.0M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -26.6% | 46,752 | $4.9M |
| Assetmark, Inc. | 0.01% | Add +16195.4% | 46,442 | $4.9M |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.