Protagonist TherapeuticsPTGX

13F holders, Q1 2025 (March 31)
275holders +34
69new positions
35sold out
7famous investors
$48.36avg. 13F price*

At the end of Q1 2025, 275 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 34 from Q4 2024. 69 opened new positions and 35 sold out. The largest holders were BlackRock, Inc. ($470.9M), Farallon Capital Management, L.L.C. ($295.3M) and RTW Investments, LP ($276.6M). 7 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).

Company
Protagonist Therapeutics Inc.
CUSIP
74366E102
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 184Q1 2024Q2 2024: 188Q2 2024Q3 2024: 240Q3 2024Q4 2024: 241Q4 2024Q1 2025: 275Q1 2025Q2 2025: 273Q2 2025Q3 2025: 275Q3 2025Q4 2025: 316Q4 2025Q1 2026: 320Q1 2026Q2 2026: 343Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions69$165.8M
Exits35$133.0M

All 13F filers, Q4 2024 → Q1 2025: 9,431,521 shares bought and 7,719,420 shares sold, net +1,712,101 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 275 holders

BlackRock, Inc. 0.01% Reduce -1.5% 9,736,767 $470.9M
Farallon Capital Management, L.L.C. 1.59% Add +3.0% 6,107,006 $295.3M
RTW Investments, LP 4.23% Add +4.0% 5,719,415 $276.6M
Vanguard Group Inc. 0.00% Add +1.4% 4,277,218 $206.8M
Deep Track Capital, LP 4.70% Add +200.0% 3,000,000 $145.1M
State Street Corp. 0.01% Reduce -18.8% 2,706,619 $130.9M
BVF Inc. 5.08% Add +35.5% 2,575,015 $124.5M
Johnson & Johnson 34.65% No change 2,449,183 $118.4M
Geode Capital Management, LLC 0.01% Add +3.4% 1,423,559 $68.9M
T. Rowe Price Associates Inc. 0.01% Reduce -5.1% 1,322,006 $63.9M
Perceptive Advisors LLC 1.87% Reduce -14.2% 1,091,271 $52.8M
Wellington Management Group LLP 0.01% Add +5.0% 987,370 $47.7M
ADAR1 Capital Management, LLC 9.00% Reduce -7.9% 939,669 $45.4M
Woodline Partners LP 0.28% Add +54.2% 897,699 $43.4M
Invesco Ltd. 0.01% Add +16.3% 859,648 $41.6M
Lynx1 Capital Management LP 12.69% New 733,014 $35.4M
American Century Companies Inc. 0.02% Reduce -26.1% 685,824 $33.2M
Northern Trust Corp. 0.00% Add +1.7% 639,507 $30.9M
Jefferies Financial Group Inc. 0.55% Reduce -57.6% 631,893 $30.6M
Charles Schwab Investment Management Inc. 0.01% Reduce -3.6% 557,718 $27.0M
Goldman Sachs Group Inc. 0.01% Reduce -26.8% 555,551 $26.9M
Eversept Partners, LP 2.99% Reduce -19.4% 547,116 $26.5M
683 Capital Management, LLC 2.69% Add +21.9% 500,000 $24.2M
Morgan Stanley 0.00% Reduce -8.0% 497,105 $24.0M
FMR LLC 0.00% Add +8.1% 478,343 $23.1M
Bank of America Corp. 0.00% Add +249.8% 471,745 $22.8M
JPMorgan Chase & Co. 0.00% Reduce -18.7% 468,899 $22.7M
Toronto Dominion Bank 0.06% Add +30.6% 445,440 $21.5M
Focus Partners Wealth 0.05% Add +2.2% 435,097 $21.0M
Affinity Asset Advisors, LLC 3.21% Add +207.7% 400,000 $19.3M
Mangrove Partners Im, LLC 2.20% No change 395,383 $19.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.05% Add +201.6% 379,649 $18.4M
Bank of New York Mellon Corp 0.00% Reduce -3.6% 376,863 $18.2M
UBS Group AG 0.00% Add +166.1% 352,871 $17.1M
Principal Financial Group Inc. 0.01% Add +2.8% 347,095 $16.8M
Adage Capital Partners Gp, L.L.C. 0.03% New 343,504 $16.6M
Qube Research & Technologies Ltd 0.03% Add +10.0% 343,411 $16.6M
Artia Global Partners LP 4.73% Add +13.6% 333,851 $16.1M
Renaissance Technologies 0.02% Add +46.3% 323,567 $15.6M
Raymond James Financial Inc. 0.01% Reduce -1.5% 298,827 $14.5M
Pictet Asset Management Holding SA 0.02% Reduce -0.3% 295,593 $14.3M
Schonfeld Strategic Advisors LLC 0.09% New 287,301 $13.9M
Skandinaviska Enskilda Banken AB (publ) 0.06% Reduce -19.9% 248,950 $12.0M
Driehaus Capital Management LLC 0.11% Reduce -30.8% 235,073 $11.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -27.5% 208,756 $10.1M
Burney Co./ 0.36% New 201,985 $9.8M
Jane Street Group, LLC 0.02% Add +214.1% 193,300 $9.3M
Susquehanna International Group, LLP 0.02% Add +174.9% 192,239 $9.3M
Public Sector Pension Investment Board 0.04% Add +27.3% 189,031 $9.1M
Checkpoint Capital L.P. 4.65% New 175,184 $8.5M
TD Asset Management Inc 0.01% Reduce -2.2% 169,932 $8.2M
Soleus Capital Management, L.P. 0.64% Reduce -38.5% 169,000 $8.2M
Jupiter Asset Management Ltd. 0.08% New 168,063 $8.1M
Moody Aldrich Partners LLC 1.66% Add +142.5% 163,483 $7.9M
Rhumbline Advisers 0.01% Add +0.1% 162,065 $7.8M
Citadel Advisors 0.01% Reduce -6.1% 154,067 $7.5M
Nuveen, LLC 0.00% — 152,771 $7.4M
Great Lakes Advisors, LLC 0.07% Add +145.9% 152,318 $7.4M
Panagora Asset Management Inc. 0.04% New 149,908 $7.2M
Legal & General Group Plc 0.00% Reduce -2.9% 148,107 $7.2M
Kennedy Capital Management LLC 0.16% Reduce -57.2% 137,504 $6.6M
Ameriprise Financial Inc. 0.00% Reduce -3.2% 136,842 $6.6M
Millennium Management 0.01% New 134,269 $6.5M
Jacobs Levy Equity Management, Inc. 0.02% No change 128,654 $6.2M
Man Group plc 0.02% Reduce -18.6% 128,606 $6.2M
Citigroup Inc. 0.00% Add +0.7% 121,844 $5.9M
Dimensional Fund Advisors LP 0.00% Reduce -46.1% 121,554 $5.9M
Nan Fung Group Holdings Ltd 4.79% New 121,400 $5.9M
Manufacturers Life Insurance Company, The 0.01% Reduce -2.8% 120,850 $5.8M
Barclays PLC 0.00% Reduce -12.1% 111,432 $5.4M
Opaleye Management Inc. 1.16% No change 105,000 $5.1M
Trexquant Investment LP 0.06% Add +12.1% 103,983 $5.0M
Empowered Funds, LLC 0.07% New 102,532 $5.0M
Victory Capital Management Inc. 0.01% Reduce -57.5% 102,411 $5.0M
Lazard Asset Management LLC 0.01% New 96,420 $4.7M
Swiss National Bank 0.00% No change 86,900 $4.2M
Aquilo Capital Management, LLC 10.65% Add +6.7% 81,692 $4.0M
First Trust Advisors LP 0.00% Reduce -42.0% 81,686 $4.0M
Franklin Resources Inc. 0.00% Reduce -11.1% 79,044 $3.8M
Northwestern Mutual Wealth Management Co. 0.00% No change 78,894 $3.8M
HighVista Strategies LLC 1.46% Add +25.5% 78,452 $3.8M
Knott David M Jr 1.73% Add +45.1% 76,000 $3.7M
EFG Asset Management (North America) Corp. 0.57% New 71,134 $3.4M
Global IMC LLC 0.92% New 69,750 $3.4M
HRT Financial LP 0.02% Add +762.8% 69,242 $3.3M
Informed Momentum Co LLC 0.58% New 69,181 $3.3M
Alliancebernstein L.P. 0.00% Reduce -0.5% 67,900 $3.3M
Deutsche Bank AG 0.00% Reduce -52.4% 65,695 $3.2M
J. Goldman & Co LP 0.11% New 65,244 $3.2M
Voya Investment Management LLC 0.00% Reduce -27.8% 59,678 $2.9M
Trek Financial, LLC 0.20% New 58,413 $2.8M
Prudential Financial Inc. 0.00% Reduce -2.7% 58,358 $2.8M
Jump Financial, LLC 0.04% New 56,780 $2.7M
Silvercrest Asset Management Group LLC 0.02% Reduce -35.2% 54,723 $2.6M
State of Wisconsin Investment Board 0.01% Add +5.8% 53,740 $2.6M
State of New Jersey Common Pension Fund D 0.01% New 53,736 $2.6M
Alps Advisors Inc. 0.01% Reduce -5.3% 52,974 $2.6M
Hussman Strategic Advisors, Inc. 0.62% Reduce -50.0% 52,500 $2.5M
CANADA LIFE ASSURANCE Co 0.00% Reduce -9.9% 50,955 $2.5M
Stempoint Capital LP 0.76% Reduce -65.3% 49,241 $2.4M
Birchview Capital, LP 2.02% Add +0.0% 48,002 $2.3M
D. E. Shaw & Co. 0.00% Add +730.3% 47,361 $2.3M
New York State Teachers Retirement System 0.01% Add +90.5% 46,855 $2.3M
Assenagon Asset Management S.A. 0.00% Reduce -14.1% 44,872 $2.2M
Rafferty Asset Management, LLC 0.01% Reduce -53.6% 44,257 $2.1M
Thrivent Financial for Lutherans 0.00% Reduce -5.0% 43,776 $2.1M
Tudor Investment Corporation 0.02% New 42,583 $2.1M
California State Teachers Retirement System 0.00% Reduce -1.2% 41,856 $2.0M
AQR Capital Management 0.00% Reduce -73.3% 40,087 $1.9M
Axiom Investors LLC 0.02% New 39,969 $1.9M
Wells Fargo & Company 0.00% Add +2.6% 39,809 $1.9M
Sei Investments Co. 0.00% Add +52.8% 37,528 $1.8M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +0.9% 37,403 $1.8M
MetLife Investment Management, LLC 0.01% Reduce -2.8% 34,790 $1.7M
State of Alaska, Department of Revenue 0.02% Reduce -2.5% 33,023 $1.6M
Massachusetts Financial Services Co. 0.00% Reduce -2.2% 31,726 $1.5M
Corebridge Financial, Inc. 0.01% Reduce -0.4% 31,020 $1.5M
Intech Investment Management LLC 0.02% Reduce -1.6% 30,982 $1.5M
Louisiana State Employees Retirement System 0.03% Reduce -2.4% 28,100 $1.4M
Exchange Traded Concepts, LLC 0.02% Add +2572.4% 27,392 $1.3M
Ensign Peak Advisors, Inc 0.00% No change 27,036 $1.3M
State of Tennessee, Department of Treasury 0.00% Reduce -2.2% 26,485 $1.3M
Hennion & Walsh Asset Management, Inc. 0.06% Reduce -18.7% 26,066 $1.3M
Quadrature Capital Ltd 0.03% New 26,061 $1.3M
Simplex Trading, LLC 0.04% Add +372.6% 25,934 $1.3M
Jain Global LLC 0.02% New 24,867 $1.2M
Gotham Asset Management 0.01% New 23,072 $1.1M
Mackenzie Financial Corp. 0.00% Add +6.3% 22,698 $1.1M
Yousif Capital Management, LLC 0.01% Reduce -2.5% 22,337 $1.1M
Inspire Investing, LLC 0.13% Add +106.9% 21,834 $1.1M
Janus Henderson Group PLC 0.00% No change 21,454 $1.0M
WINTON GROUP Ltd 0.06% Reduce -22.3% 20,795 $1.0M
Glenmede Trust Co. NA 0.01% Add +130.8% 20,666 $999K
Comerica Bank 0.00% Reduce -1.5% 20,241 $979K
Teachers Retirement System of the State of Kentucky 0.01% No change 20,200 $977K
Y-Intercept (Hong Kong) Ltd 0.07% New 20,169 $975K
Verition Fund Management LLC 0.01% New 19,847 $960K
Coppell Advisory Solutions LLC 0.13% New 20,765 $947K
New York State Common Retirement Fund 0.00% Add +9.5% 19,582 $947K
Illinois Municipal Retirement Fund 0.01% Reduce -41.8% 19,509 $943K
Tidal Investments LLC 0.01% Reduce -7.6% 19,410 $939K
Campbell & CO Investment Adviser LLC 0.07% New 19,015 $920K
STRS Ohio 0.00% Reduce -19.1% 19,000 $919K
Guggenheim Capital LLC 0.01% Reduce -0.9% 18,905 $914K
China Universal Asset Management Co., Ltd. 0.08% Add +48.5% 18,772 $908K
Algert Global LLC 0.02% Add +5.3% 18,665 $903K
Jennison Associates LLC 0.00% New 18,317 $886K
Scientech Research LLC 0.23% Add +51.6% 18,271 $884K
Bellevue Group AG 0.02% Reduce -25.7% 17,622 $852K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.01% — 17,600 $851K
Maryland State Retirement & Pension System 0.02% Reduce -13.7% 17,398 $841K
Creative Planning 0.00% Add +168.8% 17,333 $838K
Amalgamated Bank 0.01% Reduce -2.7% 16,938 $819K
ProShare Advisors LLC 0.00% Reduce -18.1% 16,758 $810K
Envestnet Asset Management Inc. 0.00% Add +85.7% 16,679 $807K
Mariner, LLC 0.00% Reduce -7.5% 16,631 $804K
State Board of Administration of Florida Retirement System 0.00% No change 16,303 $788K
Brevan Howard Capital Management LP 0.02% New 16,114 $779K
DekaBank Deutsche Girozentrale 0.00% No change 15,800 $771K
Harvest Investment Services, LLC 0.21% New 15,911 $769K
Moran Wealth Management, LLC 0.03% Reduce -0.4% 15,895 $769K
Engineers Gate Manager LP 0.01% New 15,327 $741K
Aquatic Capital Management LLC 0.02% New 15,107 $731K
Handelsbanken Fonder AB 0.00% Reduce -18.2% 14,400 $696K
Commonwealth of Pennsylvania Public School Empls Retrmt SYS 0.00% Add +12.1% 14,262 $690K
XTX Topco Ltd 0.04% Add +111.4% 14,257 $689K
BNP Paribas Financial Markets 0.00% Reduce -27.2% 14,169 $685K
Oregon Public Employees Retirement Fund 0.01% Reduce -2.1% 13,700 $663K
Erste Asset Management GmbH 0.01% No change 13,500 $660K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% New 13,340 $645K
Aviva PLC 0.00% Reduce -9.8% 13,200 $638K
Cibc World Markets Corp. 0.01% Add +141.0% 13,178 $637K
Police & Firemen's Retirement System of New Jersey 0.01% Add +3.9% 12,928 $625K
Springhill Fund Asset Management (HK) Co Ltd 2.98% New 12,859 $622K
Arizona State Retirement System 0.00% Reduce -0.0% 12,801 $619K
Royce & Associates LP 0.01% New 12,255 $593K
Teacher Retirement System of Texas 0.00% Reduce -8.2% 12,025 $582K
Gsa Capital Partners LLP 0.05% New 11,963 $579K
Profund Advisors LLC 0.02% Reduce -44.0% 11,559 $559K
Franklin Street Advisors Inc. 0.04% No change 11,300 $546K
Magnetar Financial LLC 0.01% New 11,154 $539K
Cache Advisors, LLC 0.19% No change 10,143 $491K
Royal Bank of Canada 0.00% Add +30.6% 9,964 $482K
Cerity Partners LLC 0.00% Reduce -29.2% 9,245 $447K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -6.3% 9,092 $440K
Cambria Investment Management, L.P. 0.03% Reduce -14.9% 9,000 $435K
Bank of Montreal 0.00% Add +43.0% 8,936 $432K
Quantessence Capital LLC 0.11% New 8,900 $430K
KLP Kapitalforvaltning As 0.00% No change 8,700 $421K
Mutual of America Capital Management LLC 0.00% Reduce -3.9% 8,679 $420K
Advantage Alpha Capital Partners LP 0.10% Add +50.4% 8,634 $418K
HSBC Holdings PLC 0.00% Add +4.1% 8,458 $405K
Occudo Quantitative Strategies LP 0.05% New 8,281 $405K
Landscape Capital Management, L.L.C. 0.03% New 7,758 $375K
Capula Management Ltd 0.00% New 7,684 $372K
Fred Alger Management, LLC 0.00% New 7,477 $362K
New Vernon Capital Holdings II LLC 0.19% Add +135.2% 7,198 $348K
Orion Porfolio Solutions, LLC 0.00% New 6,731 $326K
Orion Portfolio Solutions, LLC 0.00% New 6,731 $326K
HighTower Advisors, LLC 0.00% New 6,518 $315K
Allianz Asset Management GmbH 0.00% Reduce -41.8% 6,400 $310K
King Wealth Management Group 0.04% No change 6,000 $290K
Ameritas Investment Partners, Inc. 0.01% No change 5,912 $286K
SummitTX Capital, L.P. 0.01% — 5,900 $285K
Caprock Group, LLC 0.01% Add +1.5% 5,890 $285K
Two Sigma Investments, LP 0.00% Add +1.5% 5,741 $278K
Kestra Advisory Services, LLC 0.00% Reduce -8.3% 5,181 $251K
Cornerstone Investment Partners, LLC 0.01% Reduce -8.1% 4,977 $241K
LPL Financial LLC 0.00% New 4,888 $236K
Advisors Asset Management, Inc. 0.00% Add +81.7% 4,721 $228K
Xponance LLC 0.00% New 4,464 $216K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% New 4,196 $203K
E Fund Management Co., Ltd. 0.01% Reduce -94.6% 4,137 $200K
Virtu Financial LLC 0.01% New 4,140 $200K
Virtus Investment Advisers, LLC 0.05% New 4,065 $197K
US Bancorp \de 0.00% Add +71.5% 3,654 $177K
Russell Investments Group, Ltd. 0.00% Add +11479.3% 3,358 $162K
Quadrant Capital Group LLC 0.01% New 3,278 $159K
Acadian Asset Management LLC 0.00% Reduce -48.6% 3,026 $146K
Nisa Investment Advisors, LLC 0.00% Reduce -9.6% 2,832 $137K
Caitong International Asset Management Co., Ltd 0.10% New 2,788 $135K
AlphaQuest LLC 0.01% Add +24.2% 2,704 $131K
Penserra Capital Management LLC 0.00% New 2,429 $117K
Covestor Ltd 0.07% Add +27.0% 2,087 $101K
KBC Group NV 0.00% No change 2,093 $101K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +3.4% 2,054 $100K
PNC Financial Services Group, Inc. 0.00% Add +38.2% 1,992 $96K
Amundi 0.00% Add +1.2% 2,058 $96K
GF Fund Management Co. LTD. 0.00% Add +22.0% 1,526 $74K
State of Wyoming 0.01% Reduce -81.4% 1,457 $70K
Brooklyn Investment Group 0.01% New 1,400 $68K
Aster Capital Management (DIFC) Ltd 0.01% New 1,617 $61K
Smartleaf Asset Management LLC 0.01% Add +141.7% 1,211 $59K
GAMMA Investing LLC 0.00% Add +153.3% 1,203 $58K
Osaic Holdings, Inc. 0.00% Add +11.5% 660 $32K
Farther Finance Advisors, LLC 0.00% Add +784.1% 389 $18K
Assetmark, Inc. 0.00% Add +20.4% 295 $14K
Macquarie Group Ltd. 0.00% New 283 $14K
Fifth Third Bancorp 0.00% Add +206.5% 282 $14K
Truvestments Capital LLC 0.00% Add +114.5% 281 $14K
SVB Wealth LLC 0.00% New 261 $13K
Tower Research Capital LLC (TRC) 0.00% Reduce -96.9% 231 $11K
Rise Advisors, LLC 0.00% New 224 $11K
Daiwa Securities Group Inc. 0.00% No change 215 $10K
Cwm, LLC 0.00% Reduce -47.7% 202 $10K
Bessemer Group Inc. 0.00% Reduce -7.5% 186 $9K
UMB Bank, n.a. 0.00% Reduce -3.1% 158 $8K
Lindbrook Capital, LLC 0.00% Add +116.7% 143 $7K
Larson Financial Group LLC 0.00% Add +740.0% 126 $6K
Clearstead Advisors, LLC 0.00% No change 110 $5K
Danske Bank A/S 0.00% No change 100 $5K
Coldstream Capital Management Inc. 0.00% New 99 $5K
Rothschild Investment LLC 0.00% Add +111.1% 95 $5K
Signaturefd, LLC 0.00% New 94 $5K
EverSource Wealth Advisors, LLC 0.00% Add +790.0% 89 $4K
CoreCap Advisors, LLC 0.00% Reduce -6.6% 71 $3K
Sterling Capital Management LLC 0.00% Add +5.0% 63 $3K
MassMutual Private Wealth & Trust, FSB 0.00% Reduce -11.8% 45 $2K
Wolff Wiese Magana LLC 0.00% No change 35 $2K
Farmers & Merchants Investments Inc. 0.00% No change 35 $2K
Parkside Financial Bank & Trust 0.00% Add +750.0% 34 $2K
Bell Investment Advisors, Inc 0.00% Add +82.3% 31 $2K
Allworth Financial LP 0.00% New 30 $1K
Parallel Advisors, LLC 0.00% No change 27 $1K
Kestra Investment Management, LLC 0.00% New 27 $1K
Picton Mahoney Asset Management 0.00% No change 25 $1K
Stephens Consulting, LLC 0.00% New 20 $968
Creative Financial Designs Inc. 0.00% New 20 $967
Geneos Wealth Management Inc. 0.00% New 12 $580
Optiver Holding B.V. 0.00% New 11 $532
Principal Securities, Inc. 0.00% No change 12 $463
WPG Advisers, LLC 0.00% New 8 $387
Abound Wealth Management 0.00% No change 4 $194
TFC Financial Management, Inc. 0.00% New 1 $49
Hantz Financial Services, Inc. 0.00% New 2 $0

"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.