Uniqure NVQURE
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 219 institutions reported holding Uniqure NV (QURE) in their 13F filings, up 76 from Q2 2025. 96 opened new positions and 20 sold out. The largest holders were FMR LLC ($353.7M), Avoro Capital Advisors LLC ($259.4M) and RTW Investments, LP ($258.3M). 5 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Uniqure NV
- CUSIP
- N90064101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 96 | $524.4M |
| Exits | 20 | $28.4M |
All 13F filers, Q2 2025 → Q3 2025: 19,317,115 shares bought and 16,922,551 shares sold, net +2,394,564 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 219 holders
| FMR LLC | 0.02% | Add +411.6% | 6,059,574 | $353.7M |
| Avoro Capital Advisors LLC | 3.36% | Add +22.6% | 4,444,444 | $259.4M |
| RTW Investments, LP | 3.18% | Reduce -14.2% | 4,424,968 | $258.3M |
| EcoR1 Capital, LLC | 11.20% | No change | 3,988,971 | $232.8M |
| Aberdeen Group plc | 0.27% | Add +6.9% | 2,939,743 | $171.6M |
| Franklin Resources Inc. | 0.03% | Add +23.9% | 1,988,581 | $116.1M |
| BlackRock, Inc. | 0.00% | Add +8.4% | 1,446,099 | $84.4M |
| State Street Corp. | 0.00% | Add +26.4% | 1,444,010 | $84.3M |
| Fred Alger Management, LLC | 0.29% | New | 1,290,391 | $75.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -36.4% | 1,149,351 | $67.1M |
| Vanguard Group Inc. | 0.00% | Add +15.7% | 1,125,108 | $65.7M |
| 683 Capital Management, LLC | 5.94% | Reduce -16.7% | 1,070,000 | $62.5M |
| Nantahala Capital Management, LLC | 3.64% | Reduce -50.9% | 1,007,492 | $58.8M |
| Jennison Associates LLC | 0.03% | Add +613.6% | 999,484 | $58.3M |
| T. Rowe Price Associates Inc. | 0.01% | New | 913,180 | $53.3M |
| Two Sigma Investments, LP | 0.08% | Reduce -4.6% | 897,538 | $52.4M |
| Eversept Partners, LP | 3.92% | New | 877,373 | $51.2M |
| Boxer Capital Management, LLC | 14.89% | Reduce -11.1% | 800,000 | $46.7M |
| Geode Capital Management, LLC | 0.00% | Add +19.6% | 721,652 | $42.1M |
| Goldman Sachs Group Inc. | 0.01% | Add +85.8% | 662,208 | $38.7M |
| Artia Global Partners LP | 6.77% | New | 658,839 | $38.5M |
| Integral Health Asset Management, LLC | 2.55% | Reduce -55.6% | 600,000 | $35.0M |
| Farallon Capital Management, L.L.C. | 0.19% | Add +3935.7% | 565,000 | $33.0M |
| Stempoint Capital LP | 6.15% | Reduce -8.8% | 522,155 | $30.5M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 2.35% | New | 521,677 | $30.5M |
| Deep Track Capital, LP | 0.79% | New | 483,092 | $28.2M |
| Orbimed Advisors LLC | 0.64% | New | 458,500 | $26.8M |
| Caption Management, LLC | 1.62% | Add +159.1% | 458,300 | $26.8M |
| Silverarc Capital Management, LLC | 3.85% | Add +124.6% | 455,000 | $26.6M |
| Citadel Advisors | 0.02% | Reduce -22.7% | 429,710 | $25.1M |
| Two Sigma Advisers, LP | 0.05% | Reduce -37.9% | 409,500 | $23.9M |
| Darwin Global Management, Ltd. | 0.66% | New | 400,000 | $23.8M |
| Privium Fund Management B.V. | 4.05% | Reduce -13.7% | 386,000 | $22.5M |
| BNP Paribas Financial Markets | 0.02% | Reduce -23.4% | 385,609 | $22.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +22.1% | 357,685 | $20.9M |
| Parkman Healthcare Partners LLC | 2.21% | Reduce -22.1% | 345,356 | $20.2M |
| Balyasny Asset Management L.P. | 0.04% | Reduce -37.9% | 333,235 | $19.5M |
| Morgan Stanley | 0.00% | Reduce -64.6% | 321,501 | $18.8M |
| Logos Global Management LP | 1.73% | New | 300,000 | $17.5M |
| Affinity Asset Advisors, LLC | 1.68% | Add +122.2% | 300,000 | $17.5M |
| Bank of America Corp. | 0.00% | Add +108.1% | 295,131 | $17.2M |
| Catalio Capital Management, LP | 3.05% | Reduce -32.2% | 282,940 | $16.5M |
| Siren, L.L.C. | 0.63% | New | 275,200 | $16.1M |
| Macquarie Group Ltd. | 0.02% | Reduce -63.4% | 258,211 | $15.1M |
| Point72 Asset Management | 0.03% | Add +139.8% | 254,082 | $14.8M |
| Susquehanna International Group, LLP | 0.02% | Add +367.1% | 225,540 | $13.2M |
| Vestal Point Capital, LP | 0.60% | Reduce -93.9% | 225,000 | $13.1M |
| Royal Bank of Canada | 0.00% | Reduce -46.0% | 211,413 | $12.3M |
| UBS Group AG | 0.00% | Reduce -22.3% | 204,989 | $12.0M |
| Soleus Capital Management, L.P. | 0.62% | New | 200,000 | $11.7M |
| Ra Capital Management, L.P. | 0.14% | New | 200,000 | $11.7M |
| Millennium Management | 0.01% | Add +44.4% | 191,600 | $11.2M |
| Schonfeld Strategic Advisors LLC | 0.08% | Add +39.5% | 188,197 | $11.0M |
| Squarepoint Ops LLC | 0.02% | Add +3.4% | 181,902 | $10.6M |
| Lord, Abbett & Co. LLC | 0.03% | New | 176,025 | $10.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -79.1% | 158,943 | $9.3M |
| Northern Trust Corp. | 0.00% | Add +21.3% | 152,437 | $8.9M |
| Russell Investments Group, Ltd. | 0.01% | Add +40.7% | 149,851 | $8.7M |
| Boone Capital Management LLC | 2.82% | New | 147,317 | $8.6M |
| Group One Trading LLC | 0.24% | Add +120.2% | 140,227 | $8.2M |
| Sofinnova Investments, Inc. | 0.49% | Reduce -91.2% | 136,862 | $8.0M |
| ADAR1 Capital Management, LLC | 0.78% | New | 133,316 | $7.8M |
| Woodline Partners LP | 0.04% | Reduce -25.7% | 130,615 | $7.6M |
| Rosalind Advisors, Inc. | 2.58% | New | 125,000 | $7.3M |
| Voss Capital, LP | 0.42% | No change | 125,000 | $7.3M |
| Barclays PLC | 0.00% | Add +29.8% | 115,562 | $6.7M |
| Marshall Wace, LLP | 0.01% | Reduce -51.5% | 108,210 | $6.3M |
| Quinn Opportunity Partners LLC | 0.46% | New | 107,600 | $6.3M |
| Walleye Capital LLC | 0.05% | New | 102,909 | $6.0M |
| Voya Investment Management LLC | 0.01% | Add +51.8% | 102,124 | $6.0M |
| TD Asset Management Inc | 0.00% | New | 95,144 | $5.6M |
| Jefferies Financial Group Inc. | 0.05% | Reduce -95.7% | 90,542 | $5.3M |
| Atika Capital Management LLC | 0.45% | New | 90,000 | $5.3M |
| Sanders Morris Harris LLC | 0.68% | New | 87,054 | $5.1M |
| Marex Group Ltd | 0.06% | New | 86,859 | $5.1M |
| Rafferty Asset Management, LLC | 0.02% | Add +20.4% | 82,856 | $4.8M |
| Birchview Capital, LP | 3.47% | Reduce -20.2% | 78,728 | $4.6M |
| Swiss National Bank | 0.00% | Reduce -1.6% | 76,300 | $4.5M |
| Patient Square Capital LP | 1.17% | New | 75,000 | $4.4M |
| Simplex Trading, LLC | 0.09% | Add +5.8% | 67,995 | $4.0M |
| Sei Investments Co. | 0.00% | New | 67,273 | $3.9M |
| Apis Capital Advisors, LLC | 0.82% | New | 63,800 | $3.7M |
| Cubist Systematic Strategies, LLC | 0.05% | New | 62,365 | $3.6M |
| Ikarian Capital, LLC | 0.69% | Reduce -51.1% | 58,610 | $3.4M |
| Stifel Financial Corp. | 0.00% | Reduce -13.0% | 58,276 | $3.4M |
| Verition Fund Management LLC | 0.02% | Reduce -37.4% | 57,968 | $3.4M |
| Headlands Technologies LLC | 0.27% | Add +35.3% | 57,408 | $3.4M |
| Longaeva Partners L.P. | 0.69% | New | 55,000 | $3.2M |
| Hennion & Walsh Asset Management, Inc. | 0.11% | Add +70.0% | 51,613 | $3.0M |
| Owl Creek Asset Management, L.P. | 0.33% | New | 49,389 | $2.9M |
| Manufacturers Life Insurance Company, The | 0.00% | New | 48,762 | $2.8M |
| CI Investments Inc. | 0.01% | New | 47,436 | $2.8M |
| Walleye Trading LLC | 0.04% | New | 47,321 | $2.8M |
| Atom Investors LP | 0.21% | New | 47,291 | $2.8M |
| PFM Health Sciences, LP | 0.23% | Reduce -73.4% | 46,353 | $2.7M |
| LPL Financial LLC | 0.00% | New | 46,114 | $2.7M |
| WINTON GROUP Ltd | 0.09% | New | 40,976 | $2.4M |
| Monashee Investment Management LLC | 1.20% | New | 40,000 | $2.3M |
| Alyeska Investment Group, L.P. | 0.01% | New | 40,000 | $2.3M |
| Monaco Asset Management SAM | 0.88% | Reduce -43.0% | 39,913 | $2.3M |
| Boothbay Fund Management, LLC | 0.06% | Add +17.2% | 39,403 | $2.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +0.2% | 37,289 | $2.2M |
| Legal & General Group Plc | 0.00% | No change | 35,621 | $2.1M |
| Militia Capital Partners, LP | 0.95% | Add +57.7% | 35,000 | $2.0M |
| Shay Capital LLC | 0.37% | Reduce -64.8% | 34,997 | $2.0M |
| Gilder Gagnon Howe & Co. LLC | 0.02% | New | 34,084 | $2.0M |
| Diamond Hill Capital Management, LLC (Investment Advisor) | 0.01% | Reduce -59.7% | 33,333 | $1.9M |
| Superstring Capital Management LP | 1.91% | New | 33,175 | $1.9M |
| D. E. Shaw & Co. | 0.00% | Add +18.2% | 32,537 | $1.9M |
| Velan Capital Investment Management LP | 1.75% | New | 32,000 | $1.9M |
| California State Teachers Retirement System | 0.00% | Reduce -19.1% | 31,311 | $1.8M |
| Sectoral Asset Management Inc. | 1.11% | Reduce -44.6% | 30,740 | $1.8M |
| Invesco Ltd. | 0.00% | Reduce -81.9% | 30,264 | $1.8M |
| Susquehanna Portfolio Strategies, LLC | 0.03% | New | 29,548 | $1.7M |
| Scientech Research LLC | 0.60% | New | 29,295 | $1.7M |
| Tudor Investment Corporation | 0.01% | New | 28,717 | $1.7M |
| Virtu Financial LLC | 0.09% | Add +42.1% | 28,201 | $1.6M |
| Sphera Funds Management LTD. | 0.34% | New | 24,900 | $1.5M |
| Algert Global LLC | 0.02% | Add +17.9% | 22,810 | $1.3M |
| Y-Intercept (Hong Kong) Ltd | 0.03% | Reduce -63.7% | 22,704 | $1.3M |
| Aristides Capital LLC | 0.39% | New | 22,500 | $1.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -93.6% | 22,211 | $1.3M |
| Exome Asset Management LLC | 0.85% | New | 22,090 | $1.3M |
| Palumbo Wealth Management LLC | 0.41% | New | 21,778 | $1.3M |
| Wolverine Trading, LLC | 0.02% | Add +45.7% | 20,098 | $1.2M |
| Resolute Capital Asset Partners LLC | 0.61% | New | 20,000 | $1.2M |
| Massar Capital Management, LP | 0.42% | Reduce -50.0% | 20,000 | $1.2M |
| Burkehill Global Management, LP | 0.07% | New | 20,000 | $1.2M |
| Perceptive Advisors LLC | 0.03% | New | 20,000 | $1.2M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +0.5% | 19,897 | $1.2M |
| Janus Henderson Group PLC | 0.00% | Add +17.8% | 19,900 | $1.2M |
| Polymer Capital Management (US) LLC | 0.14% | New | 17,835 | $1.0M |
| Profund Advisors LLC | 0.03% | Add +24.6% | 17,084 | $997K |
| Sassicaia Capital Advisers LLC | 0.42% | New | 16,000 | $934K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Add +0.2% | 15,450 | $902K |
| Aquatic Capital Management LLC | 0.02% | Reduce -57.1% | 15,125 | $883K |
| Raymond James Financial Inc. | 0.00% | Reduce -63.5% | 14,698 | $858K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Reduce -2.5% | 12,439 | $726K |
| Prelude Capital Management, LLC | 0.06% | New | 12,160 | $710K |
| DNB Asset Management AS | 0.00% | Reduce -53.1% | 11,802 | $689K |
| Citigroup Inc. | 0.00% | Reduce -43.5% | 11,575 | $676K |
| Envestnet Asset Management Inc. | 0.00% | New | 11,549 | $674K |
| Wells Fargo & Company | 0.00% | Reduce -0.9% | 10,843 | $633K |
| SG Americas Securities, LLC | 0.00% | Reduce -88.8% | 10,579 | $617K |
| Corient Private Wealth LP | 0.00% | Reduce -0.6% | 10,562 | $617K |
| Arizona State Retirement System | 0.00% | Reduce -11.1% | 10,514 | $614K |
| China Universal Asset Management Co., Ltd. | 0.05% | Reduce -12.5% | 9,617 | $561K |
| Mraz, Amerine & Associates, Inc. | 0.08% | New | 9,319 | $544K |
| Teacher Retirement System of Texas | 0.00% | Reduce -20.0% | 8,646 | $505K |
| KLP Kapitalforvaltning As | 0.00% | No change | 8,400 | $490K |
| Sig Brokerage, LP | 0.12% | New | 7,831 | $457K |
| Campbell & CO Investment Adviser LLC | 0.03% | New | 7,771 | $454K |
| Total Clarity Wealth Management, Inc. | 0.12% | Reduce -38.9% | 7,608 | $444K |
| Virtus Investment Advisers, LLC | 0.12% | Add +21.0% | 7,116 | $415K |
| Clear Harbor Asset Management, LLC | 0.03% | Reduce -42.9% | 7,000 | $409K |
| Tema ETFs LLC | 0.03% | New | 6,250 | $365K |
| NEOS Investment Management LLC | 0.00% | New | 6,250 | $365K |
| SCS Capital Management LLC | 0.00% | New | 6,164 | $360K |
| Pictet Asset Management Holding SA | 0.00% | New | 5,900 | $344K |
| SummitTX Capital, L.P. | 0.01% | Reduce -92.7% | 5,698 | $333K |
| Lido Advisors, LLC | 0.00% | New | 5,544 | $324K |
| Diametric Capital, LP | 0.12% | New | 5,383 | $314K |
| Ballentine Partners, LLC | 0.00% | New | 5,153 | $301K |
| Activest Wealth Management | 0.06% | No change | 5,000 | $292K |
| Financial Engines Advisors L.L.C. | 0.00% | New | 4,767 | $278K |
| Bellevue Group AG | 0.01% | Reduce -75.7% | 4,763 | $278K |
| Creative Planning | 0.00% | New | 4,735 | $276K |
| Sigma Planning Corp | 0.01% | New | 4,500 | $263K |
| Hudson Bay Capital Management LP | 0.00% | Reduce -97.1% | 4,318 | $252K |
| Requisite Capital Management, LLC | 0.04% | New | 4,092 | $239K |
| Coppell Advisory Solutions LLC | 0.03% | New | 4,000 | $238K |
| IQ EQ FUND MANAGEMENT (SINGAPORE) PRIVATE Ltd | 0.31% | New | 3,900 | $228K |
| Commonwealth Equity Services, LLC | 0.00% | New | 3,880 | $226K |
| Westfield Capital Management Co. LP | 0.00% | New | 3,828 | $223K |
| Jump Financial, LLC | 0.00% | New | 3,826 | $223K |
| State of Wisconsin Investment Board | 0.00% | New | 3,568 | $208K |
| Ensign Peak Advisors, Inc | 0.00% | New | 3,000 | $175K |
| Deutsche Bank AG | 0.00% | New | 2,330 | $136K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.3% | 2,121 | $124K |
| Knott David M Jr | 0.05% | New | 2,000 | $117K |
| FNY Investment Advisers, LLC | 0.03% | Add +76.7% | 1,654 | $96K |
| Point72 Europe (London) LLP | 0.00% | New | 1,552 | $91K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -5.5% | 1,180 | $69K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -34.2% | 1,138 | $66K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -85.3% | 1,042 | $61K |
| Rockefeller Capital Management L.P. | 0.00% | New | 1,000 | $58K |
| T. Rowe Price Investment Management, Inc. | 0.00% | New | 977 | $58K |
| CIBC Private Wealth Group LLC | 0.00% | New | 850 | $50K |
| US Bancorp \de | 0.00% | Reduce -4.3% | 705 | $41K |
| Jones Financial Companies LLLP | 0.00% | Add +509.0% | 609 | $33K |
| Private Trust Co. NA | 0.00% | New | 485 | $28K |
| Comerica Bank | 0.00% | Add +66.8% | 407 | $24K |
| First Horizon Corp. | 0.00% | — | 386 | $23K |
| Salem Investment Counselors Inc. | 0.00% | No change | 300 | $18K |
| Global Retirement Partners, LLC | 0.00% | New | 300 | $18K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 250 | $15K |
| Signaturefd, LLC | 0.00% | No change | 249 | $15K |
| Cwm, LLC | 0.00% | Add +5.6% | 247 | $14K |
| UMB Bank, n.a. | 0.00% | New | 200 | $12K |
| WPG Advisers, LLC | 0.01% | New | 196 | $11K |
| Quadrant Capital Group LLC | 0.00% | New | 187 | $11K |
| Allworth Financial LP | 0.00% | Add +6.1% | 174 | $10K |
| Toth Financial Advisory Corp. | 0.00% | No change | 165 | $10K |
| Versant Capital Management, Inc | 0.00% | Reduce -33.7% | 165 | $10K |
| Daiwa Securities Group Inc. | 0.00% | No change | 158 | $9K |
| Washington Trust Advisors, Inc. | 0.00% | New | 121 | $7K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -49.8% | 116 | $7K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 109 | $6K |
| Osaic Holdings, Inc. | 0.00% | No change | 111 | $6K |
| LRI Investments, LLC | 0.00% | New | 87 | $5K |
| Grove Bank & Trust | 0.00% | New | 70 | $4K |
| Arax Advisory Partners | 0.00% | New | 67 | $4K |
| Ancora Advisors LLC | 0.00% | New | 51 | $3K |
| Bellevue Asset Management, LLC | 0.00% | New | 46 | $3K |
| Principal Securities, Inc. | 0.00% | New | 19 | $1K |
| MAI Capital Management | 0.00% | New | 11 | $643 |
| Larson Financial Group LLC | 0.00% | New | 8 | $467 |
| GAMMA Investing LLC | 0.00% | New | 4 | $233 |
| Huntington National Bank | 0.00% | No change | 2 | $117 |
"% of holder's portfolio" is QURE's weight in each manager's 13F, not the share of Uniqure NV the manager owns.