Rhythm PharmaceuticalsRYTM
13F holders, Q2 2025 (June 30)227holders −1
31new positions
32sold out
7famous investors
$63.19avg. 13F price*
At the end of Q2 2025, 227 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, down 1 from Q1 2025. 31 opened new positions and 32 sold out. The largest holders were BlackRock, Inc. ($396.0M), Baker Bros. Advisors LP ($354.1M) and Ra Capital Management, L.P. ($351.4M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $115.8M |
| Exits | 32 | $75.0M |
All 13F filers, Q1 2025 → Q2 2025: 7,625,763 shares bought and 5,899,495 shares sold, net +1,726,268 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 227 holders
| BlackRock, Inc. | 0.01% | Reduce -8.6% | 6,267,538 | $396.0M |
| Baker Bros. Advisors LP | 3.44% | No change | 5,604,483 | $354.1M |
| Ra Capital Management, L.P. | 5.92% | Reduce -8.6% | 5,561,359 | $351.4M |
| Primecap Management Co. | 0.24% | Reduce -15.7% | 4,878,037 | $308.2M |
| Vanguard Group Inc. | 0.00% | Add +4.2% | 3,589,114 | $226.8M |
| NEA Management Company, LLC | 13.84% | No change | 2,909,956 | $183.9M |
| Perceptive Advisors LLC | 5.73% | Reduce -5.1% | 2,418,299 | $152.8M |
| FMR LLC | 0.01% | Add +15.7% | 1,953,441 | $123.4M |
| State Street Corp. | 0.00% | Reduce -3.2% | 1,907,601 | $120.5M |
| Goldman Sachs Group Inc. | 0.02% | Add +5.8% | 1,733,722 | $109.6M |
| Federated Hermes, Inc. | 0.20% | Add +5.9% | 1,686,494 | $106.6M |
| Westfield Capital Management Co. LP | 0.43% | Add +21.5% | 1,629,468 | $103.0M |
| Janus Henderson Group PLC | 0.04% | Reduce -14.7% | 1,411,902 | $89.3M |
| T. Rowe Price Associates Inc. | 0.01% | Add +11.9% | 1,341,392 | $84.8M |
| Geode Capital Management, LLC | 0.01% | Add +1.9% | 1,311,253 | $82.9M |
| Driehaus Capital Management LLC | 0.64% | Reduce -12.9% | 1,269,952 | $80.2M |
| Polar Capital Holdings Plc | 0.42% | Add +150.2% | 1,250,870 | $79.0M |
| Checkpoint Capital L.P. | 31.21% | Add +16.8% | 1,060,000 | $67.0M |
| Alkeon Capital Management LLC | 0.31% | Add +24.5% | 1,017,700 | $64.3M |
| Rock Springs Capital Management LP | 3.40% | Add +3.2% | 861,153 | $54.4M |
| JPMorgan Chase & Co. | 0.00% | Add +445.5% | 783,559 | $49.5M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -2.4% | 591,454 | $37.4M |
| Sofinnova Investments, Inc. | 2.52% | Add +31.1% | 586,010 | $37.0M |
| Franklin Resources Inc. | 0.01% | Add +66.7% | 543,802 | $34.4M |
| Hood River Capital Management LLC | 0.48% | Reduce -17.6% | 543,688 | $34.4M |
| Morgan Stanley | 0.00% | Add +4.0% | 524,480 | $33.1M |
| Woodline Partners LP | 0.17% | New | 514,381 | $32.5M |
| Northern Trust Corp. | 0.00% | Reduce -4.8% | 510,246 | $32.2M |
| Opaleye Management Inc. | 6.21% | Reduce -3.1% | 475,000 | $30.0M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.6% | 461,438 | $29.2M |
| Pictet Asset Management Holding SA | 0.03% | Add +60.5% | 416,115 | $26.3M |
| Siren, L.L.C. | 1.34% | Add +47.6% | 409,742 | $25.9M |
| Silverarc Capital Management, LLC | 5.18% | Add +18.7% | 400,772 | $25.3M |
| Marshall Wace, LLP | 0.03% | Reduce -29.7% | 376,242 | $23.8M |
| Barclays PLC | 0.01% | Add +247.0% | 351,198 | $22.2M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | New | 341,000 | $21.5M |
| Voloridge Investment Management, LLC | 0.08% | Reduce -19.9% | 338,804 | $21.4M |
| Renaissance Technologies | 0.03% | Add +2131.4% | 314,893 | $19.9M |
| Candriam S.C.A. | 0.11% | Add +7.2% | 312,452 | $19.7M |
| Clearbridge Investments, LLC | 0.02% | New | 312,445 | $19.7M |
| Comerica Bank | 0.07% | Add +23.3% | 301,661 | $19.1M |
| UBS Group AG | 0.00% | Reduce -7.2% | 252,582 | $16.0M |
| Orbimed Advisors LLC | 0.39% | Reduce -34.6% | 248,512 | $15.7M |
| Voya Investment Management LLC | 0.02% | Add +184.2% | 244,003 | $15.4M |
| Qube Research & Technologies Ltd | 0.02% | Add +11.2% | 240,345 | $15.2M |
| Assenagon Asset Management S.A. | 0.02% | Add +972.5% | 237,998 | $15.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +81.0% | 227,627 | $14.4M |
| Bank of America Corp. | 0.00% | Add +98.8% | 222,152 | $14.0M |
| Norges Bank | 0.00% | Reduce -7.2% | 207,389 | $13.1M |
| Lord, Abbett & Co. LLC | 0.04% | Add +50.9% | 204,275 | $12.9M |
| Millennium Management | 0.01% | Reduce -8.9% | 198,110 | $12.5M |
| Royal Bank of Canada | 0.00% | Add +149698.5% | 196,236 | $12.4M |
| Bank of New York Mellon Corp | 0.00% | Add +25.6% | 184,109 | $11.6M |
| Stempoint Capital LP | 3.60% | Add +422.7% | 176,752 | $11.2M |
| Artisan Partners Limited Partnership | 0.02% | New | 174,479 | $11.0M |
| Ameriprise Financial Inc. | 0.00% | Add +76.1% | 173,069 | $10.9M |
| Point72 Asset Management | 0.03% | Add +167.6% | 170,832 | $10.8M |
| Russell Investments Group, Ltd. | 0.01% | Add +14.1% | 130,998 | $8.3M |
| Logos Global Management LP | 1.10% | New | 130,000 | $8.2M |
| Nuveen, LLC | 0.00% | Reduce -17.3% | 121,855 | $7.7M |
| Integral Health Asset Management, LLC | 0.71% | New | 120,000 | $7.6M |
| Panagora Asset Management Inc. | 0.03% | Reduce -15.4% | 119,466 | $7.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Add +127.7% | 115,118 | $7.3M |
| BNP Paribas Financial Markets | 0.01% | Add +18.8% | 102,239 | $6.5M |
| Lazard Asset Management LLC | 0.01% | Reduce -3.6% | 99,445 | $6.3M |
| PDT Partners, LLC | 0.35% | Reduce -4.5% | 97,638 | $6.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +2.6% | 95,517 | $6.0M |
| Swiss National Bank | 0.00% | Add +1.5% | 90,600 | $5.7M |
| Rhumbline Advisers | 0.00% | Add +2.1% | 87,526 | $5.5M |
| Harbor Capital Advisors, Inc. | 0.23% | Add +12.0% | 86,546 | $5.5M |
| Neuberger Berman Group LLC | 0.00% | Add +26.8% | 86,139 | $5.4M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +36.5% | 77,983 | $4.9M |
| Susquehanna International Group, LLP | 0.01% | Reduce -6.9% | 77,262 | $4.9M |
| First Trust Advisors LP | 0.00% | Reduce -17.9% | 73,714 | $4.7M |
| Cinctive Capital Management LP | 0.25% | Add +1528.5% | 70,937 | $4.5M |
| Invesco Ltd. | 0.00% | Reduce -73.7% | 68,924 | $4.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +5.8% | 68,132 | $4.3M |
| Aberdeen Group plc | 0.01% | Reduce -37.4% | 67,657 | $4.3M |
| Cubist Systematic Strategies, LLC | 0.04% | Reduce -62.9% | 64,577 | $4.1M |
| Alliancebernstein L.P. | 0.00% | No change | 61,470 | $3.9M |
| Algert Global LLC | 0.08% | Reduce -2.0% | 60,219 | $3.8M |
| New York State Common Retirement Fund | 0.00% | Add +247.9% | 58,618 | $3.7M |
| Kennedy Capital Management LLC | 0.09% | Add +4.2% | 57,217 | $3.6M |
| TD Asset Management Inc | 0.00% | Add +11.6% | 56,000 | $3.5M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -84.8% | 54,088 | $3.4M |
| Legal & General Group Plc | 0.00% | Add +3.0% | 52,681 | $3.3M |
| Axiom Investors LLC | 0.03% | New | 52,460 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -10.6% | 51,611 | $3.3M |
| Hennion & Walsh Asset Management, Inc. | 0.13% | Reduce -43.0% | 51,079 | $3.2M |
| Samsara Biocapital, LLC | 0.65% | Reduce -63.5% | 50,476 | $3.2M |
| Nan Fung Group Holdings Ltd | 4.89% | No change | 49,120 | $3.1M |
| AQR Capital Management | 0.00% | Add +24.6% | 49,040 | $3.1M |
| Silvercrest Asset Management Group LLC | 0.02% | New | 48,775 | $3.1M |
| ADAR1 Capital Management, LLC | 0.47% | Add +23.0% | 45,390 | $2.9M |
| California State Teachers Retirement System | 0.00% | Add +0.5% | 42,917 | $2.7M |
| Wells Fargo & Company | 0.00% | Reduce -40.0% | 42,368 | $2.7M |
| Granahan Investment Management, LLC | 0.11% | New | 41,172 | $2.6M |
| Deutsche Bank AG | 0.00% | Reduce -16.0% | 36,779 | $2.3M |
| State of Wisconsin Investment Board | 0.01% | Add +8.1% | 35,708 | $2.3M |
| Dark Forest Capital Management LP | 0.09% | Add +37.1% | 34,829 | $2.2M |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.