Rhythm PharmaceuticalsRYTM
13F holders, Q1 2025 (March 31)228holders +25
43new positions
19sold out
8famous investors
$53.02avg. 13F price*
At the end of Q1 2025, 228 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 25 from Q4 2024. 43 opened new positions and 19 sold out. The largest holders were BlackRock, Inc. ($363.1M), Ra Capital Management, L.P. ($322.3M) and Primecap Management Co. ($306.6M). 8 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 43 | $128.1M |
| Exits | 19 | $17.7M |
All 13F filers, Q4 2024 → Q1 2025: 7,308,070 shares bought and 7,424,447 shares sold, net −116,377 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 228 holders
| BlackRock, Inc. | 0.01% | Reduce -1.4% | 6,854,755 | $363.1M |
| Ra Capital Management, L.P. | 5.39% | No change | 6,084,412 | $322.3M |
| Primecap Management Co. | 0.25% | Reduce -11.9% | 5,787,322 | $306.6M |
| Baker Bros. Advisors LP | 3.32% | Reduce -7.9% | 5,604,483 | $296.9M |
| Vanguard Group Inc. | 0.00% | Add +0.1% | 3,444,926 | $182.5M |
| NEA Management Company, LLC | 11.87% | No change | 2,909,956 | $154.1M |
| Perceptive Advisors LLC | 4.79% | Reduce -30.8% | 2,548,445 | $135.0M |
| State Street Corp. | 0.00% | Add +7.0% | 1,970,733 | $104.4M |
| Janus Henderson Group PLC | 0.05% | Add +35.7% | 1,655,350 | $90.7M |
| FMR LLC | 0.01% | Add +1392.7% | 1,688,375 | $89.4M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -9.6% | 1,637,908 | $86.8M |
| Federated Hermes, Inc. | 0.18% | Add +2.7% | 1,591,871 | $84.3M |
| Driehaus Capital Management LLC | 0.74% | Add +12.9% | 1,458,022 | $77.2M |
| Westfield Capital Management Co. LP | 0.35% | New | 1,341,092 | $71.0M |
| Geode Capital Management, LLC | 0.01% | Add +2.5% | 1,287,168 | $68.2M |
| T. Rowe Price Associates Inc. | 0.01% | Add +75.0% | 1,199,053 | $63.5M |
| Checkpoint Capital L.P. | 26.37% | Add +24.6% | 907,240 | $48.1M |
| Rock Springs Capital Management LP | 2.54% | Reduce -28.3% | 834,188 | $44.2M |
| Alkeon Capital Management LLC | 0.26% | Reduce -30.0% | 817,700 | $43.3M |
| Frazier Life Sciences Management, L.P. | 1.65% | Reduce -63.7% | 678,760 | $36.0M |
| Hood River Capital Management LLC | 0.60% | Add +2.5% | 659,431 | $34.9M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -2.1% | 605,764 | $32.1M |
| Northern Trust Corp. | 0.00% | Reduce -1.7% | 536,206 | $28.4M |
| Marshall Wace, LLP | 0.04% | Reduce -22.8% | 535,103 | $28.3M |
| Morgan Stanley | 0.00% | Reduce -10.0% | 504,049 | $26.7M |
| Polar Capital Holdings Plc | 0.16% | Reduce -66.7% | 500,000 | $26.5M |
| Opaleye Management Inc. | 5.92% | Reduce -2.0% | 490,000 | $26.0M |
| Sofinnova Investments, Inc. | 1.78% | Add +12.4% | 446,839 | $23.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.2% | 445,429 | $23.6M |
| Voloridge Investment Management, LLC | 0.08% | Add +11.1% | 422,868 | $22.4M |
| Orbimed Advisors LLC | 0.48% | Reduce -5.0% | 380,000 | $20.1M |
| Balyasny Asset Management L.P. | 0.05% | Add +157.1% | 355,712 | $18.8M |
| Silverarc Capital Management, LLC | 3.74% | Add +23.3% | 337,605 | $17.9M |
| Franklin Resources Inc. | 0.01% | Add +21.6% | 326,160 | $17.3M |
| Candriam S.C.A. | 0.10% | Reduce -12.3% | 291,469 | $15.4M |
| Siren, L.L.C. | 0.83% | New | 277,533 | $14.7M |
| UBS Group AG | 0.00% | Add +7.0% | 272,108 | $14.4M |
| Invesco Ltd. | 0.00% | Reduce -13.5% | 261,902 | $13.9M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -30.9% | 259,346 | $13.9M |
| Comerica Bank | 0.05% | Add +1330.2% | 244,754 | $13.0M |
| Norges Bank | 0.00% | Add +8.7% | 223,484 | $11.8M |
| Millennium Management | 0.01% | Add +1324.6% | 217,379 | $11.5M |
| Qube Research & Technologies Ltd | 0.02% | Add +127.0% | 216,193 | $11.5M |
| Cubist Systematic Strategies, LLC | 0.12% | New | 173,822 | $9.2M |
| Cormorant Asset Management, LP | 0.60% | Reduce -62.5% | 150,000 | $7.9M |
| Nuveen, LLC | 0.00% | — | 147,301 | $7.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.1% | 146,585 | $7.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -45.7% | 143,640 | $7.6M |
| Panagora Asset Management Inc. | 0.04% | New | 141,162 | $7.5M |
| Samsara Biocapital, LLC | 1.30% | Reduce -20.0% | 138,118 | $7.3M |
| Lord, Abbett & Co. LLC | 0.03% | Reduce -15.7% | 135,360 | $7.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -42.5% | 125,782 | $6.7M |
| Russell Investments Group, Ltd. | 0.01% | Add +11412.3% | 114,778 | $6.1M |
| Bank of America Corp. | 0.00% | Add +7.0% | 111,752 | $5.9M |
| Aberdeen Group plc | 0.01% | Add +34.3% | 108,129 | $5.7M |
| Lazard Asset Management LLC | 0.01% | Reduce -2.9% | 103,202 | $5.5M |
| PDT Partners, LLC | 0.38% | Add +134.5% | 102,195 | $5.4M |
| Barclays PLC | 0.00% | Reduce -25.2% | 101,217 | $5.4M |
| Ameriprise Financial Inc. | 0.00% | Add +84.2% | 98,281 | $5.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +22.4% | 93,105 | $4.9M |
| Jane Street Group, LLC | 0.01% | Add +56.0% | 91,118 | $4.8M |
| First Trust Advisors LP | 0.00% | Reduce -24.1% | 89,779 | $4.8M |
| Hennion & Walsh Asset Management, Inc. | 0.21% | Reduce -9.9% | 89,622 | $4.7M |
| Swiss National Bank | 0.00% | Reduce -1.0% | 89,300 | $4.7M |
| Citigroup Inc. | 0.00% | Add +23.6% | 86,206 | $4.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1.0% | 86,066 | $4.6M |
| Voya Investment Management LLC | 0.01% | Reduce -11.7% | 85,849 | $4.5M |
| Rhumbline Advisers | 0.00% | Add +3.6% | 85,719 | $4.5M |
| D. E. Shaw & Co. | 0.01% | Add +74.0% | 83,869 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Add +63.8% | 82,980 | $4.4M |
| Harbor Capital Advisors, Inc. | 0.19% | Add +155.5% | 77,297 | $4.1M |
| Wells Fargo & Company | 0.00% | Add +89.3% | 70,638 | $3.7M |
| Citadel Advisors | 0.00% | Add +73.3% | 70,068 | $3.7M |
| Neuberger Berman Group LLC | 0.00% | New | 67,939 | $3.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.4% | 64,386 | $3.4M |
| Point72 Asset Management | 0.01% | New | 63,842 | $3.4M |
| Alliancebernstein L.P. | 0.00% | No change | 61,470 | $3.3M |
| Algert Global LLC | 0.08% | Add +47.9% | 61,461 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Add +14.6% | 57,732 | $3.1M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -4.3% | 57,150 | $3.0M |
| Kennedy Capital Management LLC | 0.07% | New | 54,930 | $2.9M |
| Legal & General Group Plc | 0.00% | Reduce -1.3% | 51,158 | $2.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +730.3% | 50,557 | $2.7M |
| TD Asset Management Inc | 0.00% | Add +5.0% | 50,200 | $2.7M |
| Diadema Partners LP | 2.12% | Reduce -33.3% | 50,000 | $2.6M |
| Artia Global Partners LP | 0.78% | No change | 50,000 | $2.6M |
| Nan Fung Group Holdings Ltd | 2.12% | No change | 49,120 | $2.6M |
| Alps Advisors Inc. | 0.01% | Reduce -7.0% | 46,207 | $2.4M |
| Informed Momentum Co LLC | 0.41% | Reduce -28.5% | 45,108 | $2.4M |
| Deutsche Bank AG | 0.00% | Reduce -10.2% | 43,779 | $2.3M |
| California State Teachers Retirement System | 0.00% | Reduce -1.9% | 42,721 | $2.3M |
| Jump Financial, LLC | 0.03% | New | 41,760 | $2.2M |
| Aquatic Capital Management LLC | 0.06% | Add +349.7% | 41,476 | $2.2M |
| AQR Capital Management | 0.00% | Add +148.2% | 39,363 | $2.1M |
| Trexquant Investment LP | 0.02% | Add +396.6% | 38,724 | $2.1M |
| Principal Financial Group Inc. | 0.00% | Add +0.7% | 37,156 | $2.0M |
| Wedge Capital Management L L P | 0.04% | Reduce -23.6% | 36,984 | $2.0M |
| ADAR1 Capital Management, LLC | 0.39% | Add +19.2% | 36,890 | $2.0M |
| Walleye Capital LLC | 0.02% | Reduce -75.2% | 35,828 | $1.9M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +1.1% | 35,392 | $1.9M |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.