Rhythm PharmaceuticalsRYTM

13F holders, Q4 2024 (December 31)
203holders +27
38new positions
24sold out
6famous investors
$55.98avg. 13F price*

At the end of Q4 2024, 203 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 27 from Q3 2024. 38 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($389.1M), Primecap Management Co. ($367.9M) and Ra Capital Management, L.P. ($340.6M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Joel Greenblatt (0.0% of Gotham Asset Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).

Company
Rhythm Pharmaceuticals Inc.
CUSIP
76243J105
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 167Q1 2024Q2 2024: 165Q2 2024Q3 2024: 176Q3 2024Q4 2024: 203Q4 2024Q1 2025: 228Q1 2025Q2 2025: 227Q2 2025Q3 2025: 264Q3 2025Q4 2025: 281Q4 2025Q1 2026: 285Q1 2026Q2 2026: 304Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions38$67.2M
Exits24$138.9M

All 13F filers, Q3 2024 → Q4 2024: 4,160,355 shares bought and 7,094,553 shares sold, net −2,934,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 203 holders

BlackRock, Inc. 0.01% Add +0.9% 6,950,715 $389.1M
Primecap Management Co. 0.28% Reduce -8.9% 6,571,190 $367.9M
Ra Capital Management, L.P. 4.54% No change 6,084,412 $340.6M
Baker Bros. Advisors LP 3.69% Reduce -4.9% 6,084,249 $340.6M
Perceptive Advisors LLC 5.74% Add +3.4% 3,680,473 $206.0M
Vanguard Group Inc. 0.00% Reduce -0.1% 3,442,600 $192.7M
NEA Management Company, LLC 9.19% No change 2,909,956 $162.9M
Frazier Life Sciences Management, L.P. 4.36% Reduce -22.6% 1,869,808 $104.7M
State Street Corp. 0.00% Reduce -7.6% 1,840,870 $103.1M
Goldman Sachs Group Inc. 0.02% Reduce -53.3% 1,812,206 $101.4M
Federated Hermes, Inc. 0.19% Reduce -6.9% 1,549,635 $86.7M
Polar Capital Holdings Plc 0.47% No change 1,500,000 $84.0M
Driehaus Capital Management LLC 0.60% Reduce -0.7% 1,290,975 $72.3M
Geode Capital Management, LLC 0.01% Reduce -0.0% 1,255,799 $70.3M
Janus Henderson Group PLC 0.03% Add +103.9% 1,219,554 $68.3M
Alkeon Capital Management LLC 0.38% No change 1,167,700 $65.4M
Rock Springs Capital Management LP 2.48% Reduce -5.3% 1,162,718 $65.1M
Checkpoint Capital L.P. 20.74% Add +9.7% 727,982 $40.8M
Marshall Wace, LLP 0.05% Add +70.4% 692,803 $38.8M
T. Rowe Price Associates Inc. 0.00% Add +24.4% 685,152 $38.4M
Hood River Capital Management LLC 0.53% Add +4.7% 643,691 $36.0M
Loomis Sayles & Co. L P 0.04% Reduce -2.9% 618,485 $34.6M
Morgan Stanley 0.00% Add +20.6% 560,087 $31.4M
Northern Trust Corp. 0.00% Add +9.4% 545,314 $30.5M
Opaleye Management Inc. 4.99% No change 500,000 $28.0M
Charles Schwab Investment Management Inc. 0.00% Add +1.5% 440,250 $24.6M
Cormorant Asset Management, LP 1.23% No change 400,000 $22.4M
Orbimed Advisors LLC 0.46% Reduce -8.2% 400,000 $22.4M
Sofinnova Investments, Inc. 1.63% Add +43.6% 397,428 $22.2M
Voloridge Investment Management, LLC 0.08% Add +7.7% 380,537 $21.3M
Pictet Asset Management Holding SA 0.02% Add +14.0% 375,349 $21.0M
Candriam S.C.A. 0.11% Reduce -15.9% 332,392 $18.6M
Invesco Ltd. 0.00% Add +14.5% 302,846 $17.0M
Silverarc Capital Management, LLC 3.43% Add +7.2% 273,896 $15.3M
Franklin Resources Inc. 0.00% Add +3.4% 268,205 $15.0M
JPMorgan Chase & Co. 0.00% Add +224.3% 264,585 $14.8M
UBS Group AG 0.00% Add +231.8% 254,264 $14.2M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -3.0% 218,544 $12.2M
Stempoint Capital LP 2.92% Add +404.1% 208,016 $11.6M
Norges Bank 0.00% Add +210.3% 205,649 $11.5M
Samsara Biocapital, LLC 1.33% No change 172,647 $9.7M
Lord, Abbett & Co. LLC 0.03% Add +56.5% 160,651 $9.0M
Integral Health Asset Management, LLC 0.74% New 150,000 $8.4M
Bank of New York Mellon Corp 0.00% Reduce -0.5% 148,246 $8.3M
Nuveen Asset Management, LLC 0.00% Reduce -0.7% 146,903 $8.2M
Walleye Capital LLC 0.09% New 144,342 $8.1M
Balyasny Asset Management L.P. 0.02% New 138,363 $7.7M
Barclays PLC 0.00% Add +27.3% 135,397 $7.6M
First Trust Advisors LP 0.01% Add +67.2% 118,337 $6.6M
FMR LLC 0.00% Add +124.9% 113,109 $6.3M
Lazard Asset Management LLC 0.01% New 106,261 $5.9M
Bank of America Corp. 0.00% Reduce -1.7% 104,488 $5.8M
Hennion & Walsh Asset Management, Inc. 0.25% Reduce -1.5% 99,447 $5.6M
Voya Investment Management LLC 0.01% Reduce -5.5% 97,169 $5.4M
Qube Research & Technologies Ltd 0.01% New 95,235 $5.3M
Swiss National Bank 0.00% Add +1.0% 90,200 $5.0M
BNP Paribas Financial Markets 0.00% Add +491.0% 85,249 $4.8M
Cinctive Capital Management LP 0.25% New 82,755 $4.6M
Rhumbline Advisers 0.00% Add +2.5% 82,731 $4.6M
Aberdeen Group plc 0.01% Reduce -28.6% 80,517 $4.5M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% — 76,084 $4.3M
Diadema Partners LP 4.73% — 75,000 $4.2M
Citigroup Inc. 0.00% Add +69.4% 69,777 $3.9M
Informed Momentum Co LLC 0.50% New 63,078 $3.5M
Alliancebernstein L.P. 0.00% Add +3.2% 61,470 $3.4M
Manufacturers Life Insurance Company, The 0.00% Add +23.1% 59,969 $3.4M
Schonfeld Strategic Advisors LLC 0.02% Add +95.5% 59,700 $3.3M
Jane Street Group, LLC 0.01% Reduce -46.5% 58,415 $3.3M
Global IMC LLC 0.57% New 56,936 $3.2M
Ameriprise Financial Inc. 0.00% Add +27.4% 53,367 $3.0M
Legal & General Group Plc 0.00% Add +1.9% 51,803 $2.9M
Susquehanna International Group, LLP 0.00% Add +135.8% 50,664 $2.8M
Rafferty Asset Management, LLC 0.01% Reduce -22.0% 50,394 $2.8M
Artia Global Partners LP 1.13% New 50,000 $2.8M
Alps Advisors Inc. 0.02% New 49,700 $2.8M
Nan Fung Group Holdings Ltd 2.35% No change 49,120 $2.7M
Deutsche Bank AG 0.00% Add +46.5% 48,745 $2.7M
Wedge Capital Management L L P 0.05% Reduce -0.9% 48,411 $2.7M
D. E. Shaw & Co. 0.00% Add +1022.5% 48,198 $2.7M
TD Asset Management Inc 0.00% Add +50.3% 47,800 $2.7M
PDT Partners, LLC 0.22% Add +279.0% 43,583 $2.4M
California State Teachers Retirement System 0.00% Reduce -0.9% 43,533 $2.4M
Algert Global LLC 0.05% Reduce -23.3% 41,551 $2.3M
Citadel Advisors 0.00% Reduce -60.7% 40,419 $2.3M
HighVista Strategies LLC 0.78% No change 37,426 $2.1M
Wells Fargo & Company 0.00% Add +26.6% 37,324 $2.1M
Principal Financial Group Inc. 0.00% Add +13.2% 36,884 $2.1M
State of New Jersey Common Pension Fund D 0.01% New 35,004 $2.0M
American Century Companies Inc. 0.00% New 33,766 $1.9M
Sei Investments Co. 0.00% Add +15.5% 33,522 $1.9M
MetLife Investment Management, LLC 0.01% Add +5.8% 33,498 $1.9M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +2.0% 33,156 $1.9M
State of Wisconsin Investment Board 0.00% Reduce -0.6% 32,262 $1.8M
ADAR1 Capital Management, LLC 0.37% New 30,941 $1.7M
Harbor Capital Advisors, Inc. 0.07% Reduce -26.9% 30,252 $1.7M
Intech Investment Management LLC 0.02% Add +126.8% 28,092 $1.6M
Corebridge Financial, Inc. 0.01% Reduce -7.0% 27,220 $1.5M
Wellington Management Group LLP 0.00% Reduce -7.8% 25,555 $1.4M
Crestline Management, L.P. 0.05% Add +31.9% 25,062 $1.4M
Bellevue Group AG 0.03% Add +50.3% 23,596 $1.3M

"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.

Show all 203 holders