Rhythm PharmaceuticalsRYTM
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 203 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 27 from Q3 2024. 38 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($389.1M), Primecap Management Co. ($367.9M) and Ra Capital Management, L.P. ($340.6M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Joel Greenblatt (0.0% of Gotham Asset Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 38 | $67.2M |
| Exits | 24 | $138.9M |
All 13F filers, Q3 2024 → Q4 2024: 4,160,355 shares bought and 7,094,553 shares sold, net −2,934,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 203 holders
| BlackRock, Inc. | 0.01% | Add +0.9% | 6,950,715 | $389.1M |
| Primecap Management Co. | 0.28% | Reduce -8.9% | 6,571,190 | $367.9M |
| Ra Capital Management, L.P. | 4.54% | No change | 6,084,412 | $340.6M |
| Baker Bros. Advisors LP | 3.69% | Reduce -4.9% | 6,084,249 | $340.6M |
| Perceptive Advisors LLC | 5.74% | Add +3.4% | 3,680,473 | $206.0M |
| Vanguard Group Inc. | 0.00% | Reduce -0.1% | 3,442,600 | $192.7M |
| NEA Management Company, LLC | 9.19% | No change | 2,909,956 | $162.9M |
| Frazier Life Sciences Management, L.P. | 4.36% | Reduce -22.6% | 1,869,808 | $104.7M |
| State Street Corp. | 0.00% | Reduce -7.6% | 1,840,870 | $103.1M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -53.3% | 1,812,206 | $101.4M |
| Federated Hermes, Inc. | 0.19% | Reduce -6.9% | 1,549,635 | $86.7M |
| Polar Capital Holdings Plc | 0.47% | No change | 1,500,000 | $84.0M |
| Driehaus Capital Management LLC | 0.60% | Reduce -0.7% | 1,290,975 | $72.3M |
| Geode Capital Management, LLC | 0.01% | Reduce -0.0% | 1,255,799 | $70.3M |
| Janus Henderson Group PLC | 0.03% | Add +103.9% | 1,219,554 | $68.3M |
| Alkeon Capital Management LLC | 0.38% | No change | 1,167,700 | $65.4M |
| Rock Springs Capital Management LP | 2.48% | Reduce -5.3% | 1,162,718 | $65.1M |
| Checkpoint Capital L.P. | 20.74% | Add +9.7% | 727,982 | $40.8M |
| Marshall Wace, LLP | 0.05% | Add +70.4% | 692,803 | $38.8M |
| T. Rowe Price Associates Inc. | 0.00% | Add +24.4% | 685,152 | $38.4M |
| Hood River Capital Management LLC | 0.53% | Add +4.7% | 643,691 | $36.0M |
| Loomis Sayles & Co. L P | 0.04% | Reduce -2.9% | 618,485 | $34.6M |
| Morgan Stanley | 0.00% | Add +20.6% | 560,087 | $31.4M |
| Northern Trust Corp. | 0.00% | Add +9.4% | 545,314 | $30.5M |
| Opaleye Management Inc. | 4.99% | No change | 500,000 | $28.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.5% | 440,250 | $24.6M |
| Cormorant Asset Management, LP | 1.23% | No change | 400,000 | $22.4M |
| Orbimed Advisors LLC | 0.46% | Reduce -8.2% | 400,000 | $22.4M |
| Sofinnova Investments, Inc. | 1.63% | Add +43.6% | 397,428 | $22.2M |
| Voloridge Investment Management, LLC | 0.08% | Add +7.7% | 380,537 | $21.3M |
| Pictet Asset Management Holding SA | 0.02% | Add +14.0% | 375,349 | $21.0M |
| Candriam S.C.A. | 0.11% | Reduce -15.9% | 332,392 | $18.6M |
| Invesco Ltd. | 0.00% | Add +14.5% | 302,846 | $17.0M |
| Silverarc Capital Management, LLC | 3.43% | Add +7.2% | 273,896 | $15.3M |
| Franklin Resources Inc. | 0.00% | Add +3.4% | 268,205 | $15.0M |
| JPMorgan Chase & Co. | 0.00% | Add +224.3% | 264,585 | $14.8M |
| UBS Group AG | 0.00% | Add +231.8% | 254,264 | $14.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -3.0% | 218,544 | $12.2M |
| Stempoint Capital LP | 2.92% | Add +404.1% | 208,016 | $11.6M |
| Norges Bank | 0.00% | Add +210.3% | 205,649 | $11.5M |
| Samsara Biocapital, LLC | 1.33% | No change | 172,647 | $9.7M |
| Lord, Abbett & Co. LLC | 0.03% | Add +56.5% | 160,651 | $9.0M |
| Integral Health Asset Management, LLC | 0.74% | New | 150,000 | $8.4M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.5% | 148,246 | $8.3M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -0.7% | 146,903 | $8.2M |
| Walleye Capital LLC | 0.09% | New | 144,342 | $8.1M |
| Balyasny Asset Management L.P. | 0.02% | New | 138,363 | $7.7M |
| Barclays PLC | 0.00% | Add +27.3% | 135,397 | $7.6M |
| First Trust Advisors LP | 0.01% | Add +67.2% | 118,337 | $6.6M |
| FMR LLC | 0.00% | Add +124.9% | 113,109 | $6.3M |
| Lazard Asset Management LLC | 0.01% | New | 106,261 | $5.9M |
| Bank of America Corp. | 0.00% | Reduce -1.7% | 104,488 | $5.8M |
| Hennion & Walsh Asset Management, Inc. | 0.25% | Reduce -1.5% | 99,447 | $5.6M |
| Voya Investment Management LLC | 0.01% | Reduce -5.5% | 97,169 | $5.4M |
| Qube Research & Technologies Ltd | 0.01% | New | 95,235 | $5.3M |
| Swiss National Bank | 0.00% | Add +1.0% | 90,200 | $5.0M |
| BNP Paribas Financial Markets | 0.00% | Add +491.0% | 85,249 | $4.8M |
| Cinctive Capital Management LP | 0.25% | New | 82,755 | $4.6M |
| Rhumbline Advisers | 0.00% | Add +2.5% | 82,731 | $4.6M |
| Aberdeen Group plc | 0.01% | Reduce -28.6% | 80,517 | $4.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | — | 76,084 | $4.3M |
| Diadema Partners LP | 4.73% | — | 75,000 | $4.2M |
| Citigroup Inc. | 0.00% | Add +69.4% | 69,777 | $3.9M |
| Informed Momentum Co LLC | 0.50% | New | 63,078 | $3.5M |
| Alliancebernstein L.P. | 0.00% | Add +3.2% | 61,470 | $3.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +23.1% | 59,969 | $3.4M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +95.5% | 59,700 | $3.3M |
| Jane Street Group, LLC | 0.01% | Reduce -46.5% | 58,415 | $3.3M |
| Global IMC LLC | 0.57% | New | 56,936 | $3.2M |
| Ameriprise Financial Inc. | 0.00% | Add +27.4% | 53,367 | $3.0M |
| Legal & General Group Plc | 0.00% | Add +1.9% | 51,803 | $2.9M |
| Susquehanna International Group, LLP | 0.00% | Add +135.8% | 50,664 | $2.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -22.0% | 50,394 | $2.8M |
| Artia Global Partners LP | 1.13% | New | 50,000 | $2.8M |
| Alps Advisors Inc. | 0.02% | New | 49,700 | $2.8M |
| Nan Fung Group Holdings Ltd | 2.35% | No change | 49,120 | $2.7M |
| Deutsche Bank AG | 0.00% | Add +46.5% | 48,745 | $2.7M |
| Wedge Capital Management L L P | 0.05% | Reduce -0.9% | 48,411 | $2.7M |
| D. E. Shaw & Co. | 0.00% | Add +1022.5% | 48,198 | $2.7M |
| TD Asset Management Inc | 0.00% | Add +50.3% | 47,800 | $2.7M |
| PDT Partners, LLC | 0.22% | Add +279.0% | 43,583 | $2.4M |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 43,533 | $2.4M |
| Algert Global LLC | 0.05% | Reduce -23.3% | 41,551 | $2.3M |
| Citadel Advisors | 0.00% | Reduce -60.7% | 40,419 | $2.3M |
| HighVista Strategies LLC | 0.78% | No change | 37,426 | $2.1M |
| Wells Fargo & Company | 0.00% | Add +26.6% | 37,324 | $2.1M |
| Principal Financial Group Inc. | 0.00% | Add +13.2% | 36,884 | $2.1M |
| State of New Jersey Common Pension Fund D | 0.01% | New | 35,004 | $2.0M |
| American Century Companies Inc. | 0.00% | New | 33,766 | $1.9M |
| Sei Investments Co. | 0.00% | Add +15.5% | 33,522 | $1.9M |
| MetLife Investment Management, LLC | 0.01% | Add +5.8% | 33,498 | $1.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.0% | 33,156 | $1.9M |
| State of Wisconsin Investment Board | 0.00% | Reduce -0.6% | 32,262 | $1.8M |
| ADAR1 Capital Management, LLC | 0.37% | New | 30,941 | $1.7M |
| Harbor Capital Advisors, Inc. | 0.07% | Reduce -26.9% | 30,252 | $1.7M |
| Intech Investment Management LLC | 0.02% | Add +126.8% | 28,092 | $1.6M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.0% | 27,220 | $1.5M |
| Wellington Management Group LLP | 0.00% | Reduce -7.8% | 25,555 | $1.4M |
| Crestline Management, L.P. | 0.05% | Add +31.9% | 25,062 | $1.4M |
| Bellevue Group AG | 0.03% | Add +50.3% | 23,596 | $1.3M |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.