Rhythm PharmaceuticalsRYTM
13F holders, Q1 2026 (March 31)285holders +4
55new positions
51sold out
8famous investors
$87.31avg. 13F price*
At the end of Q1 2026, 285 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 4 from Q4 2025. 55 opened new positions and 51 sold out. The largest holders were Ra Capital Management, L.P. ($579.8M), BlackRock, Inc. ($542.4M) and Baker Bros. Advisors LP ($487.4M). 8 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 55 | $87.7M |
| Exits | 51 | $479.4M |
All 13F filers, Q4 2025 → Q1 2026: 8,436,932 shares bought and 7,978,706 shares sold, net +458,226 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 285 holders
| Ra Capital Management, L.P. | 6.15% | No change | 6,666,837 | $579.8M |
| BlackRock, Inc. | 0.01% | Reduce -1.0% | 6,237,151 | $542.4M |
| Baker Bros. Advisors LP | 2.80% | No change | 5,604,483 | $487.4M |
| Primecap Management Co. | 0.23% | Reduce -1.8% | 3,417,509 | $297.2M |
| Vanguard Portfolio Management LLC | 0.01% | — | 3,040,718 | $264.5M |
| Vanguard Capital Management LLC | 0.01% | — | 2,967,825 | $258.1M |
| Perceptive Advisors LLC | 4.09% | Reduce -6.8% | 2,373,795 | $206.4M |
| State Street Corp. | 0.01% | Add +3.3% | 2,271,851 | $197.6M |
| Goldman Sachs Group Inc. | 0.02% | Add +7.3% | 1,965,432 | $170.9M |
| Westfield Capital Management Co. LP | 0.70% | Add +52.2% | 1,929,123 | $167.8M |
| FMR LLC | 0.01% | Reduce -1.0% | 1,689,671 | $147.0M |
| T. Rowe Price Associates Inc. | 0.02% | Add +6.0% | 1,654,876 | $143.9M |
| Polar Capital Holdings Plc | 0.61% | Add +36.3% | 1,615,586 | $140.5M |
| Citadel Advisors | 0.09% | Add +825.3% | 1,418,619 | $123.4M |
| Geode Capital Management, LLC | 0.01% | Add +3.0% | 1,416,269 | $123.2M |
| JPMorgan Chase & Co. | 0.01% | Add +9.1% | 1,553,644 | $120.0M |
| Federated Hermes, Inc. | 0.18% | Reduce -20.8% | 1,286,303 | $111.9M |
| Checkpoint Capital L.P. | 38.30% | Add +23.7% | 1,227,200 | $106.7M |
| Alliancebernstein L.P. | 0.03% | Reduce -2.1% | 910,413 | $97.5M |
| Capital Research Global Investors | 0.02% | Add +13.2% | 1,115,460 | $97.0M |
| Janus Henderson Group PLC | 0.04% | Reduce -18.5% | 918,153 | $79.9M |
| Point72 Asset Management | 0.13% | Add +97.2% | 846,801 | $73.6M |
| Woodline Partners LP | 0.25% | Add +10.2% | 758,891 | $66.0M |
| Adage Capital Partners Gp, L.L.C. | 0.10% | Add +16.8% | 725,744 | $63.1M |
| Siren, L.L.C. | 1.75% | Add +45.1% | 725,511 | $63.1M |
| Morgan Stanley | 0.00% | Add +8.1% | 703,978 | $61.2M |
| Rock Springs Capital Management LP | 3.54% | Reduce -0.8% | 689,748 | $60.0M |
| Pictet Asset Management Holding SA | 0.06% | Add +8.5% | 667,046 | $57.3M |
| Bank of America Corp. | 0.00% | Add +180.1% | 628,667 | $54.7M |
| Franklin Resources Inc. | 0.01% | Reduce -9.9% | 626,845 | $54.5M |
| Clearbridge Investments, LLC | 0.05% | Add +20.4% | 609,437 | $53.0M |
| Integral Health Asset Management, LLC | 2.76% | Add +26.3% | 600,000 | $52.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -1.4% | 541,450 | $47.1M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -1.1% | 526,459 | $45.8M |
| Northern Trust Corp. | 0.01% | Add +2.1% | 498,514 | $43.4M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -7.7% | 465,102 | $40.4M |
| Candriam S.C.A. | 0.21% | Add +61.3% | 464,340 | $40.4M |
| Millennium Management | 0.03% | Add +142.0% | 451,825 | $39.3M |
| Sofinnova Investments, Inc. | 1.96% | Add +65.8% | 450,096 | $39.1M |
| Logos Global Management LP | 2.02% | Add +136.8% | 450,000 | $39.1M |
| Driehaus Capital Management LLC | 0.28% | Reduce -66.0% | 436,546 | $38.0M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 421,911 | $36.7M |
| Opaleye Management Inc. | 4.65% | Reduce -62.7% | 123,000 | $35.3M |
| Artisan Partners Limited Partnership | 0.06% | Add +48.2% | 390,669 | $34.0M |
| Ameriprise Financial Inc. | 0.01% | Add +47.0% | 383,957 | $33.4M |
| Invesco Ltd. | 0.00% | Add +25.1% | 364,306 | $31.7M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -43.7% | 348,953 | $30.3M |
| Orbimed Advisors LLC | 0.62% | Add +31.0% | 314,100 | $27.3M |
| Braidwell LP | 1.03% | New | 310,628 | $27.0M |
| Silverarc Capital Management, LLC | 3.14% | Add +125.1% | 306,000 | $26.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.6% | 293,298 | $25.5M |
| Qube Research & Technologies Ltd | 0.03% | Reduce -10.6% | 277,943 | $24.2M |
| Wellington Management Group LLP | 0.00% | Add +9.4% | 273,757 | $23.8M |
| Squarepoint Ops LLC | 0.05% | Add +701.0% | 262,968 | $22.9M |
| Renaissance Technologies | 0.04% | Reduce -24.4% | 258,011 | $22.4M |
| BNP Paribas Financial Markets | 0.01% | Add +50.6% | 247,876 | $21.6M |
| Hood River Capital Management LLC | 0.21% | Add +1.2% | 239,912 | $20.9M |
| Voya Investment Management LLC | 0.02% | Reduce -6.4% | 233,810 | $20.3M |
| UBS Group AG | 0.00% | Reduce -45.8% | 231,650 | $20.1M |
| ADAR1 Capital Management, LLC | 1.11% | Add +311.8% | 211,450 | $18.4M |
| SummitTX Capital, L.P. | 0.46% | Add +105.1% | 165,599 | $14.4M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Add +1.6% | 151,842 | $13.2M |
| Deutsche Bank AG | 0.00% | Add +9.7% | 141,601 | $12.3M |
| M&G PLC | 0.06% | Add +1.1% | 138,567 | $12.1M |
| PFM Health Sciences, LP | 1.27% | Add +239.8% | 136,621 | $11.9M |
| NEXTBio Capital Management LP | 5.09% | Add +86.5% | 126,078 | $11.0M |
| New York State Common Retirement Fund | 0.02% | Add +33.7% | 125,207 | $10.9M |
| Nuveen, LLC | 0.00% | Add +1.2% | 117,376 | $10.2M |
| Schroder Investment Management Group | 0.01% | New | 131,674 | $10.2M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -13.8% | 115,712 | $10.1M |
| Capital World Investors | 0.00% | No change | 115,693 | $10.1M |
| Swiss National Bank | 0.01% | Add +0.8% | 112,200 | $9.8M |
| Axiom Investors LLC | 0.09% | Add +9.8% | 91,749 | $8.0M |
| First Light Asset Management, LLC | 0.68% | Reduce -70.5% | 87,181 | $7.6M |
| First Trust Advisors LP | 0.01% | Reduce -3.4% | 85,506 | $7.4M |
| Aberdeen Group plc | 0.01% | New | 79,357 | $6.9M |
| Granahan Investment Management, LLC | 0.33% | Add +45.4% | 77,709 | $6.8M |
| Neuberger Berman Group LLC | 0.00% | Reduce -0.2% | 73,434 | $6.4M |
| WCM Investment Management, LLC | 0.01% | Add +79.9% | 80,620 | $6.2M |
| Rhumbline Advisers | 0.01% | Reduce -1.9% | 69,858 | $6.1M |
| Kennedy Capital Management LLC | 0.12% | Add +65.0% | 65,818 | $5.7M |
| California State Teachers Retirement System | 0.01% | Add +22.9% | 65,806 | $5.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Reduce -49.0% | 62,936 | $5.5M |
| Blue Owl Capital Holdings LP | 1.44% | New | 61,455 | $5.3M |
| XTX Topco Ltd | 0.09% | Add +470.3% | 59,502 | $5.2M |
| AQR Capital Management | 0.00% | Reduce -15.4% | 59,279 | $5.2M |
| Algert Global LLC | 0.08% | Reduce -33.7% | 58,513 | $5.1M |
| Atom Investors LP | 0.35% | Add +148.6% | 57,000 | $5.0M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -26.7% | 52,967 | $4.6M |
| Castleark Management LLC | 0.15% | Reduce -18.9% | 52,279 | $4.5M |
| Susquehanna International Group, LLP | 0.01% | Add +1139.5% | 50,784 | $4.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -14.8% | 50,769 | $4.4M |
| Picton Mahoney Asset Management | 0.05% | New | 50,372 | $4.4M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -9.8% | 50,105 | $4.4M |
| Raymond James Financial Inc. | 0.00% | Add +21.4% | 49,920 | $4.3M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 49,689 | $4.3M |
| Nan Fung Group Holdings Ltd | 3.52% | No change | 49,120 | $4.3M |
| Harvest Investment Services, LLC | 0.77% | Add +10.3% | 48,468 | $4.2M |
| Legal & General Group Plc | 0.00% | Reduce -14.6% | 47,032 | $4.1M |
| Silvercrest Asset Management Group LLC | 0.03% | Add +37.4% | 46,887 | $4.1M |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.