Tango TherapeuticsTNGX
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 194 institutions reported holding Tango Therapeutics Inc. (TNGX) in their 13F filings, up 24 from Q4 2025. 52 opened new positions and 31 sold out. The largest holders were RTW Investments, LP ($278.2M), Adage Capital Partners Gp, L.L.C. ($268.0M) and Boxer Capital Management, LLC ($227.5M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Tango Therapeutics Inc.
- CUSIP
- 87583X109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 52 | $280.2M |
| Exits | 31 | $65.3M |
All 13F filers, Q4 2025 → Q1 2026: 40,698,241 shares bought and 32,911,011 shares sold, net +7,787,230 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 194 holders
| RTW Investments, LP | 2.77% | Add +791.9% | 13,300,620 | $278.2M |
| Adage Capital Partners Gp, L.L.C. | 0.41% | Add +20.8% | 12,809,485 | $268.0M |
| Boxer Capital Management, LLC | 29.87% | No change | 10,876,219 | $227.5M |
| TCG Crossover Management, LLC | 6.30% | Reduce -17.5% | 10,531,071 | $220.3M |
| FMR LLC | 0.01% | Add +245.4% | 9,905,919 | $207.2M |
| Farallon Capital Management, L.L.C. | 1.13% | Reduce -30.4% | 9,097,411 | $190.3M |
| BlackRock, Inc. | 0.00% | Add +2.4% | 8,748,045 | $183.0M |
| Woodline Partners LP | 0.63% | Reduce -20.6% | 8,000,013 | $167.4M |
| Nextech Invest Ltd. | 10.70% | No change | 7,266,081 | $152.0M |
| TRV GP Iv, LLC | 49.96% | Reduce -19.1% | 6,374,574 | $133.4M |
| Siren, L.L.C. | 3.28% | Reduce -30.7% | 5,657,105 | $118.3M |
| Vanguard Capital Management LLC | 0.00% | — | 5,161,431 | $108.0M |
| Goldman Sachs Group Inc. | 0.01% | Add +2.7% | 5,076,392 | $106.2M |
| State Street Corp. | 0.00% | Reduce -25.2% | 4,651,894 | $97.3M |
| Deerfield Management Company, L.P. | 1.21% | Add +42.6% | 4,146,813 | $86.8M |
| Paradigm Biocapital Advisors LP | 1.71% | New | 4,009,679 | $83.9M |
| Holocene Advisors, LP | 0.20% | New | 3,932,603 | $82.3M |
| Balyasny Asset Management L.P. | 0.17% | Reduce -27.5% | 3,826,659 | $80.1M |
| Logos Global Management LP | 3.23% | Reduce -28.6% | 3,000,000 | $62.8M |
| Deep Track Capital, LP | 1.19% | Add +12.0% | 2,750,000 | $57.5M |
| Geode Capital Management, LLC | 0.00% | Add +4.8% | 2,675,777 | $56.0M |
| Caligan Partners LP | 3.56% | Reduce -35.4% | 2,408,798 | $50.4M |
| Bellevue Group AG | 1.19% | Reduce -38.9% | 2,400,000 | $50.2M |
| Janus Henderson Group PLC | 0.02% | Reduce -9.4% | 2,394,972 | $50.1M |
| Vivo Capital, LLC | 3.75% | No change | 2,154,780 | $45.1M |
| Morgan Stanley | 0.00% | Add +3.9% | 1,477,488 | $30.9M |
| Cormorant Asset Management, LP | 1.50% | New | 1,425,000 | $29.8M |
| Franklin Resources Inc. | 0.01% | Reduce -7.3% | 1,296,283 | $27.1M |
| Candriam S.C.A. | 0.14% | Add +79.1% | 1,269,246 | $26.6M |
| Nantahala Capital Management, LLC | 1.64% | Reduce -65.0% | 1,250,452 | $26.2M |
| Vanguard Portfolio Management LLC | 0.00% | — | 901,466 | $18.9M |
| T. Rowe Price Associates Inc. | 0.00% | Add +1422.1% | 889,400 | $18.6M |
| Northern Trust Corp. | 0.00% | Add +7.4% | 862,940 | $18.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -0.3% | 838,675 | $17.5M |
| Perceptive Advisors LLC | 0.34% | Add +57.5% | 808,153 | $16.9M |
| Bessemer Group Inc. | 0.02% | No change | 708,398 | $14.8M |
| ArrowMark Colorado Holdings LLC | 0.39% | No change | 708,385 | $14.8M |
| UBS Group AG | 0.00% | Reduce -29.4% | 699,352 | $14.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 662,921 | $13.9M |
| Invesco Ltd. | 0.00% | Add +226.8% | 580,453 | $12.1M |
| Boothbay Fund Management, LLC | 0.29% | Reduce -40.3% | 571,350 | $12.0M |
| Point72 Asset Management | 0.02% | Reduce -73.0% | 533,937 | $11.2M |
| Ameriprise Financial Inc. | 0.00% | New | 506,158 | $10.6M |
| Seven Fleet Capital Management LP | 3.30% | Add +133.3% | 502,012 | $10.5M |
| Dimensional Fund Advisors LP | 0.00% | Add +0.5% | 489,348 | $10.2M |
| Integral Health Asset Management, LLC | 0.50% | Add +125.0% | 450,000 | $9.4M |
| Soleus Capital Management, L.P. | 0.38% | Add +4400.0% | 450,000 | $9.4M |
| Acuta Capital Partners, LLC | 6.57% | Add +56.3% | 441,831 | $9.2M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Reduce -1.4% | 440,015 | $9.2M |
| Millennium Management | 0.01% | Reduce -28.2% | 425,644 | $8.9M |
| PFM Health Sciences, LP | 0.91% | New | 406,245 | $8.5M |
| Sofinnova Investments, Inc. | 0.41% | New | 395,081 | $8.3M |
| Rock Springs Capital Management LP | 0.48% | No change | 386,915 | $8.1M |
| Nuveen, LLC | 0.00% | Add +20.1% | 360,818 | $7.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +174.4% | 355,229 | $7.4M |
| Mass General Brigham, Inc | 1.58% | No change | 354,192 | $7.4M |
| Sphera Funds Management LTD. | 1.24% | Reduce -36.9% | 343,563 | $7.2M |
| Congress Asset Management Co. | 0.05% | Add +45.5% | 341,361 | $7.1M |
| Bank of America Corp. | 0.00% | Reduce -31.6% | 327,144 | $6.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -7.4% | 318,458 | $6.7M |
| DV Trading LLC | 0.57% | New | 300,648 | $6.3M |
| Wellington Management Group LLP | 0.00% | Add +23.7% | 289,180 | $6.0M |
| Parkman Healthcare Partners LLC | 0.58% | New | 266,127 | $5.6M |
| KVP Capital Advisors, LP | 3.60% | New | 230,264 | $4.8M |
| Cinctive Capital Management LP | 0.31% | New | 222,111 | $4.6M |
| Stempoint Capital LP | 0.81% | New | 200,919 | $4.2M |
| TRV GP Vi, LLC | 3.00% | No change | 194,174 | $4.1M |
| Schroder Investment Management Group | 0.00% | New | 207,504 | $4.0M |
| Citadel Advisors | 0.00% | Add +18.1% | 179,423 | $3.8M |
| Squarepoint Ops LLC | 0.01% | Add +2.9% | 178,915 | $3.7M |
| Voya Investment Management LLC | 0.00% | Add +267.0% | 175,469 | $3.7M |
| Atle Fund Management AB | 1.17% | New | 29,915 | $3.6M |
| Two Sigma Investments, LP | 0.00% | Add +19.9% | 173,132 | $3.6M |
| Informed Momentum Co LLC | 0.41% | New | 167,998 | $3.5M |
| Fisher Asset Management | 0.00% | Reduce -13.5% | 162,399 | $3.4M |
| Fred Alger Management, LLC | 0.01% | New | 150,070 | $3.1M |
| Algert Global LLC | 0.05% | New | 145,640 | $3.0M |
| Rhumbline Advisers | 0.00% | Reduce -1.9% | 126,603 | $2.6M |
| Schonfeld Strategic Advisors LLC | 0.02% | New | 120,689 | $2.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +234.6% | 108,218 | $2.3M |
| AQR Capital Management | 0.00% | Add +30.5% | 107,286 | $2.2M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -53.7% | 104,960 | $2.2M |
| HighVista Strategies LLC | 0.60% | New | 104,193 | $2.2M |
| TD Asset Management Inc | 0.00% | New | 102,600 | $2.1M |
| Deutsche Bank AG | 0.00% | Add +21.3% | 89,975 | $1.9M |
| Swiss National Bank | 0.00% | No change | 87,800 | $1.8M |
| Susquehanna International Group, LLP | 0.00% | Add +145.2% | 86,350 | $1.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +82.7% | 75,717 | $1.6M |
| Los Angeles Capital Management LLC | 0.01% | Reduce -1.6% | 63,220 | $1.3M |
| JPMorgan Chase & Co. | 0.00% | Add +18.5% | 67,326 | $1.3M |
| MetLife Investment Management, LLC | 0.01% | Add +1.7% | 60,694 | $1.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -4.9% | 59,537 | $1.2M |
| Vanguard Global Advisers, LLC | 0.00% | — | 55,755 | $1.2M |
| Creative Planning | 0.00% | Add +26.3% | 52,907 | $1.1M |
| Victory Capital Management Inc. | 0.00% | Add +417.4% | 52,801 | $1.1M |
| Atom Investors LP | 0.08% | New | 52,764 | $1.1M |
| ADAR1 Capital Management, LLC | 0.06% | Reduce -64.3% | 50,000 | $1.0M |
| Alliancebernstein L.P. | 0.00% | Add +10.4% | 117,620 | $1.0M |
| Profund Advisors LLC | 0.04% | Reduce -43.0% | 47,735 | $999K |
| California State Teachers Retirement System | 0.00% | Reduce -1.1% | 47,691 | $998K |
| SmartHarvest Portfolios, LLC | 0.40% | Add +0.5% | 46,369 | $970K |
| State of Wisconsin Investment Board | 0.00% | Add +54.6% | 45,348 | $949K |
| Wells Fargo & Company | 0.00% | Reduce -65.4% | 41,972 | $878K |
| Intech Investment Management LLC | 0.01% | Reduce -2.5% | 37,959 | $794K |
| Rockefeller Capital Management L.P. | 0.00% | Add +3997.0% | 36,340 | $760K |
| Janney Montgomery Scott LLC | 0.00% | No change | 36,000 | $753K |
| Legal & General Group Plc | 0.00% | Reduce -10.3% | 35,375 | $740K |
| New York State Common Retirement Fund | 0.00% | Add +36.2% | 33,476 | $700K |
| Allstate Corp. | 0.01% | New | 32,047 | $670K |
| Sei Investments Co. | 0.00% | Reduce -40.7% | 31,962 | $669K |
| BNP Paribas Financial Markets | 0.00% | Add +220.2% | 30,625 | $641K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +7.3% | 30,350 | $635K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 29,604 | $619K |
| Virtus Investment Advisers, LLC | 0.17% | Add +2.5% | 29,163 | $610K |
| Massachusetts Financial Services Co. | 0.00% | Reduce -2.6% | 27,298 | $571K |
| EverSource Wealth Advisors, LLC | 0.02% | Add +1.5% | 26,026 | $544K |
| Harvest Investment Services, LLC | 0.10% | New | 25,376 | $531K |
| SG Americas Securities, LLC | 0.00% | Add +10.2% | 24,257 | $507K |
| China Universal Asset Management Co., Ltd. | 0.04% | Add +8.9% | 23,900 | $500K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +15.3% | 23,517 | $492K |
| Persistent Asset Partners Ltd | 0.19% | New | 23,116 | $484K |
| ProShare Advisors LLC | 0.00% | Reduce -12.8% | 22,124 | $463K |
| Barclays PLC | 0.00% | Reduce -94.1% | 21,670 | $453K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Reduce -2.4% | 21,345 | $447K |
| State Board of Administration of Florida Retirement System | 0.00% | Add +64.7% | 21,051 | $440K |
| Entropy Technologies, LP | 0.02% | Add +39.6% | 20,656 | $432K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.64% | New | 20,463 | $428K |
| Jain Global LLC | 0.01% | New | 20,370 | $426K |
| Citigroup Inc. | 0.00% | Reduce -45.8% | 19,633 | $411K |
| Prudential Financial Inc. | 0.00% | New | 19,160 | $401K |
| Gotham Asset Management | 0.00% | New | 19,137 | $400K |
| Quantinno Capital Management LP | 0.00% | Reduce -17.4% | 18,444 | $386K |
| Alyeska Investment Group, L.P. | 0.00% | New | 17,198 | $360K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 15,210 | $318K |
| PSP Research LLC | 0.21% | New | 14,400 | $301K |
| XTX Topco Ltd | 0.01% | Reduce -62.8% | 14,095 | $295K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -34.9% | 14,000 | $293K |
| Canada Pension Plan Investment Board | 0.00% | Reduce -72.4% | 13,900 | $291K |
| E Fund Management Co., Ltd. | 0.01% | — | 13,194 | $276K |
| Russell Investments Group, Ltd. | 0.00% | Add +31.1% | 12,840 | $269K |
| Mangrove Partners Im, LLC | 0.02% | New | 12,557 | $263K |
| Tower Research Capital LLC (TRC) | 0.01% | Reduce -36.5% | 12,537 | $262K |
| SummitTX Capital, L.P. | 0.01% | New | 12,535 | $262K |
| Bleakley Financial Group, LLC | 0.00% | New | 12,381 | $259K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 12,235 | $256K |
| Arizona State Retirement System | 0.00% | Reduce -0.4% | 12,224 | $256K |
| Bridgefront Capital, LLC | 0.06% | Reduce -44.2% | 10,867 | $227K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +138.3% | 10,647 | $223K |
| Xponance LLC | 0.00% | New | 10,238 | $214K |
| Hudson Bay Capital Management LP | 0.00% | New | 10,160 | $213K |
| KLP Kapitalforvaltning As | 0.00% | No change | 9,700 | $203K |
| Abacus Wealth Partners, LLC | 0.02% | New | 9,561 | $200K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +5.3% | 9,089 | $190K |
| Quantbot Technologies LP | 0.01% | New | 7,408 | $155K |
| Nisa Investment Advisors, LLC | 0.00% | Add +316.1% | 7,240 | $151K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 7,025 | $147K |
| State of Wyoming | 0.02% | New | 6,120 | $128K |
| Cwm, LLC | 0.00% | Add +4.3% | 5,039 | $105K |
| Sterling Capital Management LLC | 0.00% | Reduce -40.0% | 3,680 | $77K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.8% | 3,011 | $63K |
| ANTIPODES PARTNERS Ltd | 0.00% | Reduce -64.1% | 1,622 | $34K |
| TFC Financial Management, Inc. | 0.00% | Add +19.2% | 1,550 | $32K |
| Simplex Trading, LLC | 0.00% | New | 1,056 | $22K |
| Kemnay Advisory Services Inc. | 0.00% | New | 1,047 | $22K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +214.1% | 1,005 | $21K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Reduce -11.8% | 904 | $19K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 817 | $17K |
| GAMMA Investing LLC | 0.00% | Add +27.0% | 606 | $13K |
| Allworth Financial LP | 0.00% | Add +1151.1% | 563 | $12K |
| Advisory Services Network, LLC | 0.00% | New | 487 | $10K |
| Osaic Holdings, Inc. | 0.00% | Reduce -38.6% | 425 | $9K |
| Optiver Holding B.V. | 0.00% | Reduce -28.8% | 410 | $9K |
| Farther Finance Advisors, LLC | 0.00% | Add +4.8% | 372 | $8K |
| Federated Hermes, Inc. | 0.00% | Reduce -2.2% | 354 | $7K |
| Royal Bank of Canada | 0.00% | Reduce -90.5% | 350 | $7K |
| Larson Financial Group LLC | 0.00% | Add +635.3% | 250 | $5K |
| IFP Advisors, Inc | 0.00% | No change | 233 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 212 | $4K |
| Fortitude Family Office, LLC | 0.00% | New | 130 | $3K |
| Jones Financial Companies LLLP | 0.00% | New | 122 | $2K |
| Rothschild Investment LLC | 0.00% | Add +230.8% | 86 | $2K |
| WPG Advisers, LLC | 0.00% | Reduce -50.9% | 78 | $2K |
| US Bancorp \de | 0.00% | New | 48 | $1K |
| Clearstead Advisors, LLC | 0.00% | No change | 45 | $942 |
| Parkside Financial Bank & Trust | 0.00% | New | 35 | $733 |
| Root Financial Partners, LLC | 0.00% | New | 34 | $711 |
| Keating Financial Advisory Services, Inc. | 0.00% | New | 29 | $607 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 19 | $397 |
| MAI Capital Management | 0.00% | New | 18 | $377 |
| Essential Partners LLC | 0.00% | No change | 4 | $84 |
| Twin Peaks Wealth Advisors, LLC | 0.00% | New | 2 | $42 |
| Hughes Financial Services, LLC | 0.00% | New | 2 | $42 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -94.7% | 1 | $21 |
| Covestor Ltd | 0.00% | Reduce -68.8% | 10 | $0 |
"% of holder's portfolio" is TNGX's weight in each manager's 13F, not the share of Tango Therapeutics Inc. the manager owns.