Tango TherapeuticsTNGX

13F holders, Q1 2026 (March 31)
194holders +24
52new positions
31sold out
6famous investors
$20.93avg. 13F price*

At the end of Q1 2026, 194 institutions reported holding Tango Therapeutics Inc. (TNGX) in their 13F filings, up 24 from Q4 2025. 52 opened new positions and 31 sold out. The largest holders were RTW Investments, LP ($278.2M), Adage Capital Partners Gp, L.L.C. ($268.0M) and Boxer Capital Management, LLC ($227.5M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Tango Therapeutics Inc.
CUSIP
87583X109
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 126Q1 2024Q2 2024: 120Q2 2024Q3 2024: 121Q3 2024Q4 2024: 137Q4 2024Q1 2025: 122Q1 2025Q2 2025: 115Q2 2025Q3 2025: 141Q3 2025Q4 2025: 170Q4 2025Q1 2026: 194Q1 2026Q2 2026: 247Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions52$280.2M
Exits31$65.3M

All 13F filers, Q4 2025 → Q1 2026: 40,698,241 shares bought and 32,911,011 shares sold, net +7,787,230 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 194 holders

RTW Investments, LP 2.77% Add +791.9% 13,300,620 $278.2M
Adage Capital Partners Gp, L.L.C. 0.41% Add +20.8% 12,809,485 $268.0M
Boxer Capital Management, LLC 29.87% No change 10,876,219 $227.5M
TCG Crossover Management, LLC 6.30% Reduce -17.5% 10,531,071 $220.3M
FMR LLC 0.01% Add +245.4% 9,905,919 $207.2M
Farallon Capital Management, L.L.C. 1.13% Reduce -30.4% 9,097,411 $190.3M
BlackRock, Inc. 0.00% Add +2.4% 8,748,045 $183.0M
Woodline Partners LP 0.63% Reduce -20.6% 8,000,013 $167.4M
Nextech Invest Ltd. 10.70% No change 7,266,081 $152.0M
TRV GP Iv, LLC 49.96% Reduce -19.1% 6,374,574 $133.4M
Siren, L.L.C. 3.28% Reduce -30.7% 5,657,105 $118.3M
Vanguard Capital Management LLC 0.00% — 5,161,431 $108.0M
Goldman Sachs Group Inc. 0.01% Add +2.7% 5,076,392 $106.2M
State Street Corp. 0.00% Reduce -25.2% 4,651,894 $97.3M
Deerfield Management Company, L.P. 1.21% Add +42.6% 4,146,813 $86.8M
Paradigm Biocapital Advisors LP 1.71% New 4,009,679 $83.9M
Holocene Advisors, LP 0.20% New 3,932,603 $82.3M
Balyasny Asset Management L.P. 0.17% Reduce -27.5% 3,826,659 $80.1M
Logos Global Management LP 3.23% Reduce -28.6% 3,000,000 $62.8M
Deep Track Capital, LP 1.19% Add +12.0% 2,750,000 $57.5M
Geode Capital Management, LLC 0.00% Add +4.8% 2,675,777 $56.0M
Caligan Partners LP 3.56% Reduce -35.4% 2,408,798 $50.4M
Bellevue Group AG 1.19% Reduce -38.9% 2,400,000 $50.2M
Janus Henderson Group PLC 0.02% Reduce -9.4% 2,394,972 $50.1M
Vivo Capital, LLC 3.75% No change 2,154,780 $45.1M
Morgan Stanley 0.00% Add +3.9% 1,477,488 $30.9M
Cormorant Asset Management, LP 1.50% New 1,425,000 $29.8M
Franklin Resources Inc. 0.01% Reduce -7.3% 1,296,283 $27.1M
Candriam S.C.A. 0.14% Add +79.1% 1,269,246 $26.6M
Nantahala Capital Management, LLC 1.64% Reduce -65.0% 1,250,452 $26.2M
Vanguard Portfolio Management LLC 0.00% — 901,466 $18.9M
T. Rowe Price Associates Inc. 0.00% Add +1422.1% 889,400 $18.6M
Northern Trust Corp. 0.00% Add +7.4% 862,940 $18.1M
Charles Schwab Investment Management Inc. 0.00% Reduce -0.3% 838,675 $17.5M
Perceptive Advisors LLC 0.34% Add +57.5% 808,153 $16.9M
Bessemer Group Inc. 0.02% No change 708,398 $14.8M
ArrowMark Colorado Holdings LLC 0.39% No change 708,385 $14.8M
UBS Group AG 0.00% Reduce -29.4% 699,352 $14.6M
Vanguard Fiduciary Trust Co. 0.00% — 662,921 $13.9M
Invesco Ltd. 0.00% Add +226.8% 580,453 $12.1M
Boothbay Fund Management, LLC 0.29% Reduce -40.3% 571,350 $12.0M
Point72 Asset Management 0.02% Reduce -73.0% 533,937 $11.2M
Ameriprise Financial Inc. 0.00% New 506,158 $10.6M
Seven Fleet Capital Management LP 3.30% Add +133.3% 502,012 $10.5M
Dimensional Fund Advisors LP 0.00% Add +0.5% 489,348 $10.2M
Integral Health Asset Management, LLC 0.50% Add +125.0% 450,000 $9.4M
Soleus Capital Management, L.P. 0.38% Add +4400.0% 450,000 $9.4M
Acuta Capital Partners, LLC 6.57% Add +56.3% 441,831 $9.2M
T. Rowe Price Investment Management, Inc. 0.01% Reduce -1.4% 440,015 $9.2M
Millennium Management 0.01% Reduce -28.2% 425,644 $8.9M
PFM Health Sciences, LP 0.91% New 406,245 $8.5M
Sofinnova Investments, Inc. 0.41% New 395,081 $8.3M
Rock Springs Capital Management LP 0.48% No change 386,915 $8.1M
Nuveen, LLC 0.00% Add +20.1% 360,818 $7.5M
Connor, Clark & Lunn Investment Management Ltd. 0.02% Add +174.4% 355,229 $7.4M
Mass General Brigham, Inc 1.58% No change 354,192 $7.4M
Sphera Funds Management LTD. 1.24% Reduce -36.9% 343,563 $7.2M
Congress Asset Management Co. 0.05% Add +45.5% 341,361 $7.1M
Bank of America Corp. 0.00% Reduce -31.6% 327,144 $6.8M
Bank of New York Mellon Corp 0.00% Reduce -7.4% 318,458 $6.7M
DV Trading LLC 0.57% New 300,648 $6.3M
Wellington Management Group LLP 0.00% Add +23.7% 289,180 $6.0M
Parkman Healthcare Partners LLC 0.58% New 266,127 $5.6M
KVP Capital Advisors, LP 3.60% New 230,264 $4.8M
Cinctive Capital Management LP 0.31% New 222,111 $4.6M
Stempoint Capital LP 0.81% New 200,919 $4.2M
TRV GP Vi, LLC 3.00% No change 194,174 $4.1M
Schroder Investment Management Group 0.00% New 207,504 $4.0M
Citadel Advisors 0.00% Add +18.1% 179,423 $3.8M
Squarepoint Ops LLC 0.01% Add +2.9% 178,915 $3.7M
Voya Investment Management LLC 0.00% Add +267.0% 175,469 $3.7M
Atle Fund Management AB 1.17% New 29,915 $3.6M
Two Sigma Investments, LP 0.00% Add +19.9% 173,132 $3.6M
Informed Momentum Co LLC 0.41% New 167,998 $3.5M
Fisher Asset Management 0.00% Reduce -13.5% 162,399 $3.4M
Fred Alger Management, LLC 0.01% New 150,070 $3.1M
Algert Global LLC 0.05% New 145,640 $3.0M
Rhumbline Advisers 0.00% Reduce -1.9% 126,603 $2.6M
Schonfeld Strategic Advisors LLC 0.02% New 120,689 $2.5M
Manufacturers Life Insurance Company, The 0.00% Add +234.6% 108,218 $2.3M
AQR Capital Management 0.00% Add +30.5% 107,286 $2.2M
Rafferty Asset Management, LLC 0.01% Reduce -53.7% 104,960 $2.2M
HighVista Strategies LLC 0.60% New 104,193 $2.2M
TD Asset Management Inc 0.00% New 102,600 $2.1M
Deutsche Bank AG 0.00% Add +21.3% 89,975 $1.9M
Swiss National Bank 0.00% No change 87,800 $1.8M
Susquehanna International Group, LLP 0.00% Add +145.2% 86,350 $1.8M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +82.7% 75,717 $1.6M
Los Angeles Capital Management LLC 0.01% Reduce -1.6% 63,220 $1.3M
JPMorgan Chase & Co. 0.00% Add +18.5% 67,326 $1.3M
MetLife Investment Management, LLC 0.01% Add +1.7% 60,694 $1.3M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -4.9% 59,537 $1.2M
Vanguard Global Advisers, LLC 0.00% — 55,755 $1.2M
Creative Planning 0.00% Add +26.3% 52,907 $1.1M
Victory Capital Management Inc. 0.00% Add +417.4% 52,801 $1.1M
Atom Investors LP 0.08% New 52,764 $1.1M
ADAR1 Capital Management, LLC 0.06% Reduce -64.3% 50,000 $1.0M
Alliancebernstein L.P. 0.00% Add +10.4% 117,620 $1.0M
Profund Advisors LLC 0.04% Reduce -43.0% 47,735 $999K
California State Teachers Retirement System 0.00% Reduce -1.1% 47,691 $998K
SmartHarvest Portfolios, LLC 0.40% Add +0.5% 46,369 $970K
State of Wisconsin Investment Board 0.00% Add +54.6% 45,348 $949K
Wells Fargo & Company 0.00% Reduce -65.4% 41,972 $878K
Intech Investment Management LLC 0.01% Reduce -2.5% 37,959 $794K
Rockefeller Capital Management L.P. 0.00% Add +3997.0% 36,340 $760K
Janney Montgomery Scott LLC 0.00% No change 36,000 $753K
Legal & General Group Plc 0.00% Reduce -10.3% 35,375 $740K
New York State Common Retirement Fund 0.00% Add +36.2% 33,476 $700K
Allstate Corp. 0.01% New 32,047 $670K
Sei Investments Co. 0.00% Reduce -40.7% 31,962 $669K
BNP Paribas Financial Markets 0.00% Add +220.2% 30,625 $641K
Police & Firemen's Retirement System of New Jersey 0.01% Add +7.3% 30,350 $635K
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 29,604 $619K
Virtus Investment Advisers, LLC 0.17% Add +2.5% 29,163 $610K
Massachusetts Financial Services Co. 0.00% Reduce -2.6% 27,298 $571K
EverSource Wealth Advisors, LLC 0.02% Add +1.5% 26,026 $544K
Harvest Investment Services, LLC 0.10% New 25,376 $531K
SG Americas Securities, LLC 0.00% Add +10.2% 24,257 $507K
China Universal Asset Management Co., Ltd. 0.04% Add +8.9% 23,900 $500K
Vanguard Personalized Indexing Management, LLC 0.00% Add +15.3% 23,517 $492K
Persistent Asset Partners Ltd 0.19% New 23,116 $484K
ProShare Advisors LLC 0.00% Reduce -12.8% 22,124 $463K
Barclays PLC 0.00% Reduce -94.1% 21,670 $453K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% Reduce -2.4% 21,345 $447K
State Board of Administration of Florida Retirement System 0.00% Add +64.7% 21,051 $440K
Entropy Technologies, LP 0.02% Add +39.6% 20,656 $432K
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.64% New 20,463 $428K
Jain Global LLC 0.01% New 20,370 $426K
Citigroup Inc. 0.00% Reduce -45.8% 19,633 $411K
Prudential Financial Inc. 0.00% New 19,160 $401K
Gotham Asset Management 0.00% New 19,137 $400K
Quantinno Capital Management LP 0.00% Reduce -17.4% 18,444 $386K
Alyeska Investment Group, L.P. 0.00% New 17,198 $360K
State of New Jersey Common Pension Fund D 0.00% New 15,210 $318K
PSP Research LLC 0.21% New 14,400 $301K
XTX Topco Ltd 0.01% Reduce -62.8% 14,095 $295K
Bridgeway Capital Management, LLC 0.01% Reduce -34.9% 14,000 $293K
Canada Pension Plan Investment Board 0.00% Reduce -72.4% 13,900 $291K
E Fund Management Co., Ltd. 0.01% — 13,194 $276K
Russell Investments Group, Ltd. 0.00% Add +31.1% 12,840 $269K
Mangrove Partners Im, LLC 0.02% New 12,557 $263K
Tower Research Capital LLC (TRC) 0.01% Reduce -36.5% 12,537 $262K
SummitTX Capital, L.P. 0.01% New 12,535 $262K
Bleakley Financial Group, LLC 0.00% New 12,381 $259K
Vanguard Investments Australia, Ltd. 0.00% — 12,235 $256K
Arizona State Retirement System 0.00% Reduce -0.4% 12,224 $256K
Bridgefront Capital, LLC 0.06% Reduce -44.2% 10,867 $227K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +138.3% 10,647 $223K
Xponance LLC 0.00% New 10,238 $214K
Hudson Bay Capital Management LP 0.00% New 10,160 $213K
KLP Kapitalforvaltning As 0.00% No change 9,700 $203K
Abacus Wealth Partners, LLC 0.02% New 9,561 $200K
Ameritas Investment Partners, Inc. 0.01% Add +5.3% 9,089 $190K
Quantbot Technologies LP 0.01% New 7,408 $155K
Nisa Investment Advisors, LLC 0.00% Add +316.1% 7,240 $151K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +7.3% 7,025 $147K
State of Wyoming 0.02% New 6,120 $128K
Cwm, LLC 0.00% Add +4.3% 5,039 $105K
Sterling Capital Management LLC 0.00% Reduce -40.0% 3,680 $77K
GF Fund Management Co. LTD. 0.00% Add +13.8% 3,011 $63K
ANTIPODES PARTNERS Ltd 0.00% Reduce -64.1% 1,622 $34K
TFC Financial Management, Inc. 0.00% Add +19.2% 1,550 $32K
Simplex Trading, LLC 0.00% New 1,056 $22K
Kemnay Advisory Services Inc. 0.00% New 1,047 $22K
Caitong International Asset Management Co., Ltd 0.00% Add +214.1% 1,005 $21K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -11.8% 904 $19K
Federation des caisses Desjardins du Quebec 0.00% New 817 $17K
GAMMA Investing LLC 0.00% Add +27.0% 606 $13K
Allworth Financial LP 0.00% Add +1151.1% 563 $12K
Advisory Services Network, LLC 0.00% New 487 $10K
Osaic Holdings, Inc. 0.00% Reduce -38.6% 425 $9K
Optiver Holding B.V. 0.00% Reduce -28.8% 410 $9K
Farther Finance Advisors, LLC 0.00% Add +4.8% 372 $8K
Federated Hermes, Inc. 0.00% Reduce -2.2% 354 $7K
Royal Bank of Canada 0.00% Reduce -90.5% 350 $7K
Larson Financial Group LLC 0.00% Add +635.3% 250 $5K
IFP Advisors, Inc 0.00% No change 233 $5K
PNC Financial Services Group, Inc. 0.00% No change 212 $4K
Fortitude Family Office, LLC 0.00% New 130 $3K
Jones Financial Companies LLLP 0.00% New 122 $2K
Rothschild Investment LLC 0.00% Add +230.8% 86 $2K
WPG Advisers, LLC 0.00% Reduce -50.9% 78 $2K
US Bancorp \de 0.00% New 48 $1K
Clearstead Advisors, LLC 0.00% No change 45 $942
Parkside Financial Bank & Trust 0.00% New 35 $733
Root Financial Partners, LLC 0.00% New 34 $711
Keating Financial Advisory Services, Inc. 0.00% New 29 $607
MassMutual Private Wealth & Trust, FSB 0.00% New 19 $397
MAI Capital Management 0.00% New 18 $377
Essential Partners LLC 0.00% No change 4 $84
Twin Peaks Wealth Advisors, LLC 0.00% New 2 $42
Hughes Financial Services, LLC 0.00% New 2 $42
SBI Securities Co., Ltd. 0.00% Reduce -94.7% 1 $21
Covestor Ltd 0.00% Reduce -68.8% 10 $0

"% of holder's portfolio" is TNGX's weight in each manager's 13F, not the share of Tango Therapeutics Inc. the manager owns.