Taysha Gene TherapiesTSHA
13F holders, Q2 2026 (June 30)At the end of Q2 2026, 208 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, up 17 from Q1 2026. 39 opened new positions and 22 sold out. The largest holders were Avoro Capital Advisors LLC ($162.7M), Ra Capital Management, L.P. ($160.4M) and Goldman Sachs Group Inc. ($154.7M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $111.1M |
| Exits | 22 | $19.0M |
All 13F filers, Q1 2026 → Q2 2026: 45,232,932 shares bought and 13,505,508 shares sold, net +31,727,424 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 208 holders
| Avoro Capital Advisors LLC | 1.46% | Add +10.1% | 23,888,888 | $162.7M |
| Ra Capital Management, L.P. | 1.39% | No change | 23,555,648 | $160.4M |
| Goldman Sachs Group Inc. | 0.02% | Add +1.5% | 22,713,118 | $154.7M |
| BlackRock, Inc. | 0.00% | Add +12.7% | 20,691,927 | $140.9M |
| Vestal Point Capital, LP | 3.09% | Add +7.9% | 19,415,000 | $132.2M |
| Morgan Stanley | 0.01% | Reduce -8.2% | 16,487,479 | $112.3M |
| RTW Investments, LP | 0.79% | Reduce -0.9% | 13,560,258 | $92.3M |
| FMR LLC | 0.00% | Reduce -6.9% | 13,336,413 | $90.8M |
| Vanguard Capital Management LLC | 0.00% | Add +22.0% | 12,478,595 | $85.0M |
| State Street Corp. | 0.00% | Add +1.9% | 11,421,920 | $77.8M |
| Siren, L.L.C. | 1.36% | Add +11.5% | 9,846,579 | $67.1M |
| Octagon Capital Advisors LP | 6.06% | Add +9.4% | 9,693,244 | $66.0M |
| Geode Capital Management, LLC | 0.00% | Add +18.6% | 6,560,394 | $44.7M |
| Polar Capital Holdings Plc | 0.10% | Reduce -9.5% | 5,117,133 | $34.8M |
| MPM Bioimpact LLC | 1.87% | New | 4,500,000 | $30.6M |
| D. E. Shaw & Co. | 0.02% | Reduce -0.7% | 4,398,652 | $30.0M |
| Baker Bros. Advisors LP | 0.14% | No change | 4,004,756 | $27.3M |
| Wellington Management Group LLP | 0.00% | Add +534.7% | 3,975,605 | $27.1M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.04% | Add +34.8% | 3,885,501 | $26.5M |
| GordonMD Global Investments LP | 11.86% | Reduce -1.9% | 723,185 | $24.5M |
| Casdin Capital, LLC | 1.11% | No change | 3,250,000 | $22.1M |
| Vanguard Portfolio Management LLC | 0.00% | Add +55.3% | 3,140,009 | $21.4M |
| ADAR1 Capital Management, LLC | 0.98% | Add +2.0% | 3,040,466 | $20.7M |
| Pictet Asset Management Holding SA | 0.02% | Add +14242.6% | 2,770,701 | $18.9M |
| Aberdeen Group plc | 0.02% | Add +127.9% | 2,327,152 | $15.8M |
| Farallon Capital Management, L.L.C. | 0.09% | New | 2,250,000 | $15.3M |
| Norges Bank | 0.00% | — | 2,233,600 | $15.2M |
| Northern Trust Corp. | 0.00% | Add +22.7% | 2,226,210 | $15.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +21.7% | 2,200,695 | $15.0M |
| Millennium Management | 0.01% | Reduce -35.2% | 2,126,838 | $14.5M |
| Orbimed Advisors LLC | 0.26% | New | 2,000,000 | $13.6M |
| Rice Hall James & Associates, LLC | 0.66% | Add +2.5% | 1,992,229 | $13.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +23.9% | 1,896,474 | $12.9M |
| B Group, Inc. | 6.96% | No change | 1,800,556 | $12.3M |
| Affinity Asset Advisors, LLC | 0.59% | Add +75.0% | 1,750,000 | $11.9M |
| Barclays PLC | 0.00% | Reduce -42.0% | 1,630,659 | $11.1M |
| Citadel Advisors | 0.01% | Add +273.4% | 1,535,287 | $10.5M |
| Heights Capital Management, Inc. | 2.40% | New | 1,500,000 | $10.2M |
| Seven Fleet Capital Management LP | 1.64% | Add +140.4% | 1,504,400 | $9.9M |
| Palo Alto Investors LP | 1.31% | No change | 1,391,382 | $9.5M |
| Bank of America Corp. | 0.00% | Reduce -18.1% | 1,372,845 | $9.3M |
| Granahan Investment Management, LLC | 0.32% | Add +47.8% | 1,305,177 | $8.9M |
| Quantum Private Wealth, LLC | 1.42% | Reduce -4.4% | 812,027 | $5.5M |
| First Trust Advisors LP | 0.00% | New | 791,169 | $5.4M |
| JPMorgan Chase & Co. | 0.00% | Add +1.5% | 766,282 | $5.2M |
| Sands Capital Alternatives, LLC | 0.80% | No change | 724,873 | $4.9M |
| Bank of New York Mellon Corp | 0.00% | Add +14.8% | 697,971 | $4.8M |
| BNP Paribas Financial Markets | 0.00% | Add +432.5% | 640,035 | $4.4M |
| Panagora Asset Management Inc. | 0.01% | Add +224.1% | 590,387 | $4.0M |
| UBS Group AG | 0.00% | Add +13.7% | 588,427 | $4.0M |
| Affinity Wealth Management LLC | 0.51% | New | 576,808 | $3.9M |
| Squarepoint Ops LLC | 0.01% | Add +38.8% | 569,269 | $3.9M |
| Acuta Capital Partners, LLC | 2.67% | Add +27.8% | 561,808 | $3.8M |
| Nuveen, LLC | 0.00% | Add +1.2% | 555,693 | $3.8M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 553,000 | $3.8M |
| Diadema Partners LP | 1.35% | New | 522,619 | $3.6M |
| Hennion & Walsh Asset Management, Inc. | 0.10% | Add +32.6% | 519,120 | $3.5M |
| Woodline Partners LP | 0.01% | No change | 513,828 | $3.5M |
| Holocene Advisors, LP | 0.01% | New | 510,000 | $3.5M |
| Ghisallo Capital Management LLC | 0.08% | New | 505,000 | $3.4M |
| Burkehill Global Management, LP | 0.13% | New | 500,000 | $3.4M |
| Polen Capital Management LLC | 0.03% | Add +53.0% | 489,219 | $3.3M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -5.2% | 464,771 | $3.2M |
| Voya Investment Management LLC | 0.00% | Reduce -16.9% | 425,363 | $2.9M |
| Trexquant Investment LP | 0.02% | New | 379,577 | $2.6M |
| Swiss National Bank | 0.00% | Add +37.3% | 369,000 | $2.5M |
| Moore Capital Management, LP | 0.06% | Add +9.0% | 358,374 | $2.4M |
| Wells Fargo & Company | 0.00% | Add +81.8% | 333,314 | $2.3M |
| Jefferies Financial Group Inc. | 0.02% | Reduce -31.4% | 328,800 | $2.2M |
| Citigroup Inc. | 0.00% | Add +437.7% | 306,907 | $2.1M |
| Rhumbline Advisers | 0.00% | Add +16.0% | 299,975 | $2.0M |
| Alps Advisors Inc. | 0.01% | Add +30.3% | 290,543 | $2.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.6% | 272,600 | $1.9M |
| Invesco Ltd. | 0.00% | Reduce -28.2% | 264,379 | $1.8M |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -4.4% | 262,896 | $1.8M |
| Qube Research & Technologies Ltd | 0.00% | New | 259,605 | $1.8M |
| Sphera Funds Management LTD. | 0.24% | New | 250,000 | $1.7M |
| Deutsche Bank AG | 0.00% | Add +33.9% | 243,379 | $1.7M |
| Two Sigma Investments, LP | 0.00% | Reduce -68.4% | 234,716 | $1.6M |
| Jane Street Group, LLC | 0.00% | New | 228,355 | $1.6M |
| SG Americas Securities, LLC | 0.00% | Reduce -90.7% | 202,260 | $1.4M |
| Monashee Investment Management LLC | 3.29% | New | 200,000 | $1.4M |
| T. Rowe Price Associates Inc. | 0.00% | Add +25.5% | 199,494 | $1.4M |
| Privium Fund Management B.V. | 0.25% | Add +9.3% | 198,900 | $1.4M |
| Victory Capital Management Inc. | 0.00% | Add +0.9% | 197,578 | $1.3M |
| Chicago Partners Investment Group LLC | 0.03% | Add +30.2% | 222,347 | $1.3M |
| Balyasny Asset Management L.P. | 0.00% | Add +128.1% | 189,332 | $1.3M |
| State of Wisconsin Investment Board | 0.00% | Reduce -32.8% | 177,089 | $1.2M |
| California State Teachers Retirement System | 0.00% | Add +23.7% | 169,374 | $1.2M |
| Raymond James Financial Inc. | 0.00% | Add +653.7% | 166,042 | $1.1M |
| Alliancebernstein L.P. | 0.00% | Add +30.9% | 247,680 | $1.1M |
| Wexford Capital LP | 0.15% | No change | 160,654 | $1.1M |
| Rafferty Asset Management, LLC | 0.00% | Reduce -48.4% | 154,706 | $1.1M |
| Palumbo Wealth Management LLC | 0.21% | Add +1.7% | 149,173 | $1.0M |
| MetLife Investment Management, LLC | 0.00% | Add +17.3% | 140,846 | $959K |
| Vanguard Global Advisers, LLC | 0.00% | Add +14.7% | 133,821 | $911K |
| Persistent Asset Partners Ltd | 0.29% | New | 133,411 | $909K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | Add +46.6% | 132,614 | $903K |
| AQR Capital Management | 0.00% | Reduce -27.4% | 128,764 | $877K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.5% | 127,915 | $870K |
| Mariner, LLC | 0.00% | New | 116,582 | $794K |
| Aquatic Capital Management LLC | 0.03% | Add +171.5% | 108,208 | $737K |
| Legal & General Group Plc | 0.00% | Add +3.7% | 108,207 | $737K |
| Franklin Resources Inc. | 0.00% | Reduce -1.9% | 106,290 | $724K |
| Engineers Gate Manager LP | 0.01% | New | 104,132 | $709K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +4.8% | 104,095 | $709K |
| XTX Topco Ltd | 0.01% | Add +879.7% | 101,195 | $689K |
| Prelude Capital Management, LLC | 0.05% | New | 98,346 | $670K |
| Profund Advisors LLC | 0.01% | Reduce -40.5% | 80,200 | $546K |
| Gsa Capital Partners LLP | 0.03% | New | 72,573 | $494K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +23.7% | 70,719 | $482K |
| New York State Common Retirement Fund | 0.00% | Add +2.7% | 69,300 | $472K |
| Jupiter Topco LLC | 0.00% | — | 69,000 | $470K |
| J. Goldman & Co LP | 0.02% | Add +99.5% | 67,349 | $459K |
| Red Reef Advisors LLC | 0.41% | No change | 65,950 | $449K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +35.2% | 65,734 | $448K |
| Creative Planning | 0.00% | Add +6.7% | 63,781 | $434K |
| Commonwealth Equity Services, LLC | 0.00% | Add +5.7% | 61,773 | $421K |
| Russell Investments Group, Ltd. | 0.00% | Add +264.5% | 61,705 | $420K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 59,100 | $402K |
| Virtus Investment Advisers, LLC | 0.09% | Add +21.7% | 57,303 | $390K |
| Lanark Financial, Inc. | 0.03% | Add +1.8% | 55,022 | $375K |
| Intech Investment Management LLC | 0.00% | Add +9.7% | 52,618 | $358K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -39.1% | 49,213 | $335K |
| KLP Kapitalforvaltning As | 0.00% | Add +63.1% | 47,800 | $326K |
| Militia Capital Management LLC | 0.06% | No change | 46,500 | $317K |
| State of New Jersey Common Pension Fund D | 0.00% | Reduce -0.8% | 46,443 | $316K |
| Williams & Novak, LLC | 0.20% | No change | 45,000 | $306K |
| Almanack Investment Partners, LLC. | 0.04% | New | 44,950 | $306K |
| First Manhattan Co. Llc. | 0.00% | No change | 43,500 | $296K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | Reduce -23.7% | 43,191 | $294K |
| Allianz Asset Management GmbH | 0.00% | No change | 42,400 | $289K |
| ProShare Advisors LLC | 0.00% | Reduce -7.8% | 40,817 | $278K |
| Arizona State Retirement System | 0.00% | Add +5.3% | 39,633 | $270K |
| Prudential Financial Inc. | 0.00% | Add +15.4% | 39,040 | $266K |
| Envestnet Asset Management Inc. | 0.00% | Add +10.9% | 37,314 | $254K |
| Vanguard Investments Australia, Ltd. | 0.00% | No change | 35,887 | $244K |
| Los Angeles Capital Management LLC | 0.00% | Add +12.8% | 32,149 | $219K |
| Cetera Investment Advisers | 0.00% | Add +11.1% | 31,607 | $215K |
| Guggenheim Capital LLC | 0.00% | Add +79.2% | 29,721 | $202K |
| Susquehanna International Group, LLP | 0.00% | Reduce -76.6% | 27,164 | $185K |
| Quadrature Capital Ltd | 0.00% | Add +9.6% | 25,753 | $175K |
| nVerses Capital, LLC | 0.26% | New | 25,152 | $171K |
| State of Wyoming | 0.02% | New | 24,382 | $166K |
| Xponance LLC | 0.00% | Add +14.2% | 22,881 | $156K |
| E Fund Management Co., Ltd. | 0.00% | Reduce -42.1% | 21,814 | $149K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +23.1% | 21,761 | $148K |
| Lee Financial Co | 0.02% | No change | 20,000 | $136K |
| Allstate Corp. | 0.00% | New | 19,447 | $132K |
| Weiss Asset Management LP | 0.00% | New | 19,144 | $130K |
| Aster Capital Management (DIFC) Ltd | 0.03% | New | 18,553 | $126K |
| Principal Financial Group Inc. | 0.00% | Add +13.3% | 18,334 | $125K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +38.6% | 17,979 | $122K |
| Teacher Retirement System of Texas | 0.00% | Reduce -5.9% | 16,736 | $114K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -32.6% | 15,075 | $103K |
| Thrivent Financial for Lutherans | 0.00% | New | 14,520 | $98K |
| St Germain D J Co. Inc. | 0.00% | Add +46.7% | 14,133 | $96K |
| Sei Investments Co. | 0.00% | Reduce -72.9% | 13,952 | $95K |
| Bank of Montreal | 0.00% | No change | 13,668 | $93K |
| Captrust Financial Advisors | 0.00% | New | 13,455 | $92K |
| Simplex Trading, LLC | 0.00% | New | 13,371 | $91K |
| CIBC Bancorp USA Inc. | 0.00% | Add +19.3% | 13,262 | $90K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -10.0% | 12,852 | $88K |
| Ethic Inc. | 0.00% | Reduce -3.6% | 12,512 | $85K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -55.8% | 11,530 | $79K |
| Magnetar Financial LLC | 0.00% | Add +0.6% | 11,475 | $78K |
| Neuberger Berman Group LLC | 0.00% | Add +3.2% | 11,170 | $76K |
| Summit Financial, LLC | 0.00% | Reduce -2.3% | 10,888 | $74K |
| Choreo, LLC | 0.00% | Add +5.7% | 10,618 | $72K |
| Capital Investment Advisors, LLC | 0.00% | No change | 10,000 | $68K |
| Osaic Holdings, Inc. | 0.00% | Add +337.5% | 8,838 | $60K |
| Royal Bank of Canada | 0.00% | Add +3767.0% | 7,386 | $51K |
| Allworth Financial LP | 0.00% | Add +28.2% | 6,978 | $48K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -5.4% | 5,797 | $39K |
| Nisa Investment Advisors, LLC | 0.00% | Add +13.2% | 5,780 | $39K |
| Rockefeller Capital Management L.P. | 0.00% | No change | 5,000 | $34K |
| SBI Securities Co., Ltd. | 0.00% | Add +20333.3% | 3,065 | $21K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 3,000 | $20K |
| Pacer Advisors, Inc. | 0.00% | New | 2,584 | $18K |
| Kemnay Advisory Services Inc. | 0.00% | New | 2,582 | $18K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Reduce -14.5% | 2,099 | $14K |
| Chung Wu Investment Group, LLC | 0.01% | No change | 2,000 | $14K |
| International Assets Investment Management, LLC | 0.00% | No change | 2,000 | $13K |
| Group One Trading LLC | 0.00% | New | 1,939 | $13K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +100.3% | 1,855 | $13K |
| Jones Financial Companies LLLP | 0.00% | Add +160.4% | 1,461 | $9K |
| US Bancorp \de | 0.00% | Add +14.4% | 1,152 | $8K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1.0% | 1,053 | $7K |
| Sterling Capital Management LLC | 0.00% | Reduce -40.3% | 842 | $6K |
| Federation des caisses Desjardins du Quebec | 0.00% | Reduce -90.0% | 500 | $3K |
| Quarry LP | 0.00% | New | 480 | $3K |
| Larson Financial Group LLC | 0.00% | Add +266.4% | 469 | $3K |
| Optiver Holding B.V. | 0.00% | Reduce -48.7% | 443 | $3K |
| Arax Advisory Partners | 0.00% | New | 360 | $2K |
| Essential Partners LLC | 0.00% | No change | 327 | $2K |
| Parallel Advisors, LLC | 0.00% | Reduce -2.1% | 280 | $2K |
| Signaturefd, LLC | 0.00% | No change | 266 | $2K |
| GAMMA Investing LLC | 0.00% | Add +71.8% | 232 | $2K |
| Rothschild Investment LLC | 0.00% | No change | 170 | $1K |
| Covestor Ltd | 0.00% | Add +248.2% | 94 | $1K |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 79 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 141 | $960 |
| National Bank of Canada | 0.00% | New | 85 | $578 |
| Farther Finance Advisors, LLC | 0.00% | No change | 55 | $375 |
| True Wealth Design, LLC | 0.00% | No change | 30 | $205 |
| Keating Financial Advisory Services, Inc. | 0.00% | Add +100.0% | 26 | $177 |
| IFP Advisors, Inc | 0.00% | No change | 14 | $95 |
| Hughes Financial Services, LLC | 0.00% | New | 6 | $41 |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.