Taysha Gene TherapiesTSHA

13F holders, Q2 2026 (June 30)
208holders +17
39new positions
22sold out
4famous investors
$6.87avg. 13F price*

At the end of Q2 2026, 208 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, up 17 from Q1 2026. 39 opened new positions and 22 sold out. The largest holders were Avoro Capital Advisors LLC ($162.7M), Ra Capital Management, L.P. ($160.4M) and Goldman Sachs Group Inc. ($154.7M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Taysha Gene Therapies Inc.
CUSIP
877619106
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 109Q1 2024Q2 2024: 107Q2 2024Q3 2024: 119Q3 2024Q4 2024: 131Q4 2024Q1 2025: 127Q1 2025Q2 2025: 150Q2 2025Q3 2025: 155Q3 2025Q4 2025: 195Q4 2025Q1 2026: 191Q1 2026Q2 2026: 208Q2 2026

Total Exit/New Position Q1 2026 → Q2 2026

InstitutionsTotal Value
New Positions39$111.1M
Exits22$19.0M

All 13F filers, Q1 2026 → Q2 2026: 45,232,932 shares bought and 13,505,508 shares sold, net +31,727,424 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 208 holders

Avoro Capital Advisors LLC 1.46% Add +10.1% 23,888,888 $162.7M
Ra Capital Management, L.P. 1.39% No change 23,555,648 $160.4M
Goldman Sachs Group Inc. 0.02% Add +1.5% 22,713,118 $154.7M
BlackRock, Inc. 0.00% Add +12.7% 20,691,927 $140.9M
Vestal Point Capital, LP 3.09% Add +7.9% 19,415,000 $132.2M
Morgan Stanley 0.01% Reduce -8.2% 16,487,479 $112.3M
RTW Investments, LP 0.79% Reduce -0.9% 13,560,258 $92.3M
FMR LLC 0.00% Reduce -6.9% 13,336,413 $90.8M
Vanguard Capital Management LLC 0.00% Add +22.0% 12,478,595 $85.0M
State Street Corp. 0.00% Add +1.9% 11,421,920 $77.8M
Siren, L.L.C. 1.36% Add +11.5% 9,846,579 $67.1M
Octagon Capital Advisors LP 6.06% Add +9.4% 9,693,244 $66.0M
Geode Capital Management, LLC 0.00% Add +18.6% 6,560,394 $44.7M
Polar Capital Holdings Plc 0.10% Reduce -9.5% 5,117,133 $34.8M
MPM Bioimpact LLC 1.87% New 4,500,000 $30.6M
D. E. Shaw & Co. 0.02% Reduce -0.7% 4,398,652 $30.0M
Baker Bros. Advisors LP 0.14% No change 4,004,756 $27.3M
Wellington Management Group LLP 0.00% Add +534.7% 3,975,605 $27.1M
Healthcare of Ontario Pension Plan Trust Fund 0.04% Add +34.8% 3,885,501 $26.5M
GordonMD Global Investments LP 11.86% Reduce -1.9% 723,185 $24.5M
Casdin Capital, LLC 1.11% No change 3,250,000 $22.1M
Vanguard Portfolio Management LLC 0.00% Add +55.3% 3,140,009 $21.4M
ADAR1 Capital Management, LLC 0.98% Add +2.0% 3,040,466 $20.7M
Pictet Asset Management Holding SA 0.02% Add +14242.6% 2,770,701 $18.9M
Aberdeen Group plc 0.02% Add +127.9% 2,327,152 $15.8M
Farallon Capital Management, L.L.C. 0.09% New 2,250,000 $15.3M
Norges Bank 0.00% — 2,233,600 $15.2M
Northern Trust Corp. 0.00% Add +22.7% 2,226,210 $15.2M
Charles Schwab Investment Management Inc. 0.00% Add +21.7% 2,200,695 $15.0M
Millennium Management 0.01% Reduce -35.2% 2,126,838 $14.5M
Orbimed Advisors LLC 0.26% New 2,000,000 $13.6M
Rice Hall James & Associates, LLC 0.66% Add +2.5% 1,992,229 $13.6M
Vanguard Fiduciary Trust Co. 0.00% Add +23.9% 1,896,474 $12.9M
B Group, Inc. 6.96% No change 1,800,556 $12.3M
Affinity Asset Advisors, LLC 0.59% Add +75.0% 1,750,000 $11.9M
Barclays PLC 0.00% Reduce -42.0% 1,630,659 $11.1M
Citadel Advisors 0.01% Add +273.4% 1,535,287 $10.5M
Heights Capital Management, Inc. 2.40% New 1,500,000 $10.2M
Seven Fleet Capital Management LP 1.64% Add +140.4% 1,504,400 $9.9M
Palo Alto Investors LP 1.31% No change 1,391,382 $9.5M
Bank of America Corp. 0.00% Reduce -18.1% 1,372,845 $9.3M
Granahan Investment Management, LLC 0.32% Add +47.8% 1,305,177 $8.9M
Quantum Private Wealth, LLC 1.42% Reduce -4.4% 812,027 $5.5M
First Trust Advisors LP 0.00% New 791,169 $5.4M
JPMorgan Chase & Co. 0.00% Add +1.5% 766,282 $5.2M
Sands Capital Alternatives, LLC 0.80% No change 724,873 $4.9M
Bank of New York Mellon Corp 0.00% Add +14.8% 697,971 $4.8M
BNP Paribas Financial Markets 0.00% Add +432.5% 640,035 $4.4M
Panagora Asset Management Inc. 0.01% Add +224.1% 590,387 $4.0M
UBS Group AG 0.00% Add +13.7% 588,427 $4.0M
Affinity Wealth Management LLC 0.51% New 576,808 $3.9M
Squarepoint Ops LLC 0.01% Add +38.8% 569,269 $3.9M
Acuta Capital Partners, LLC 2.67% Add +27.8% 561,808 $3.8M
Nuveen, LLC 0.00% Add +1.2% 555,693 $3.8M
Adage Capital Partners Gp, L.L.C. 0.01% New 553,000 $3.8M
Diadema Partners LP 1.35% New 522,619 $3.6M
Hennion & Walsh Asset Management, Inc. 0.10% Add +32.6% 519,120 $3.5M
Woodline Partners LP 0.01% No change 513,828 $3.5M
Holocene Advisors, LP 0.01% New 510,000 $3.5M
Ghisallo Capital Management LLC 0.08% New 505,000 $3.4M
Burkehill Global Management, LP 0.13% New 500,000 $3.4M
Polen Capital Management LLC 0.03% Add +53.0% 489,219 $3.3M
Dimensional Fund Advisors LP 0.00% Reduce -5.2% 464,771 $3.2M
Voya Investment Management LLC 0.00% Reduce -16.9% 425,363 $2.9M
Trexquant Investment LP 0.02% New 379,577 $2.6M
Swiss National Bank 0.00% Add +37.3% 369,000 $2.5M
Moore Capital Management, LP 0.06% Add +9.0% 358,374 $2.4M
Wells Fargo & Company 0.00% Add +81.8% 333,314 $2.3M
Jefferies Financial Group Inc. 0.02% Reduce -31.4% 328,800 $2.2M
Citigroup Inc. 0.00% Add +437.7% 306,907 $2.1M
Rhumbline Advisers 0.00% Add +16.0% 299,975 $2.0M
Alps Advisors Inc. 0.01% Add +30.3% 290,543 $2.0M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +2.6% 272,600 $1.9M
Invesco Ltd. 0.00% Reduce -28.2% 264,379 $1.8M
Ensign Peak Advisors, Inc 0.00% Reduce -4.4% 262,896 $1.8M
Qube Research & Technologies Ltd 0.00% New 259,605 $1.8M
Sphera Funds Management LTD. 0.24% New 250,000 $1.7M
Deutsche Bank AG 0.00% Add +33.9% 243,379 $1.7M
Two Sigma Investments, LP 0.00% Reduce -68.4% 234,716 $1.6M
Jane Street Group, LLC 0.00% New 228,355 $1.6M
SG Americas Securities, LLC 0.00% Reduce -90.7% 202,260 $1.4M
Monashee Investment Management LLC 3.29% New 200,000 $1.4M
T. Rowe Price Associates Inc. 0.00% Add +25.5% 199,494 $1.4M
Privium Fund Management B.V. 0.25% Add +9.3% 198,900 $1.4M
Victory Capital Management Inc. 0.00% Add +0.9% 197,578 $1.3M
Chicago Partners Investment Group LLC 0.03% Add +30.2% 222,347 $1.3M
Balyasny Asset Management L.P. 0.00% Add +128.1% 189,332 $1.3M
State of Wisconsin Investment Board 0.00% Reduce -32.8% 177,089 $1.2M
California State Teachers Retirement System 0.00% Add +23.7% 169,374 $1.2M
Raymond James Financial Inc. 0.00% Add +653.7% 166,042 $1.1M
Alliancebernstein L.P. 0.00% Add +30.9% 247,680 $1.1M
Wexford Capital LP 0.15% No change 160,654 $1.1M
Rafferty Asset Management, LLC 0.00% Reduce -48.4% 154,706 $1.1M
Palumbo Wealth Management LLC 0.21% Add +1.7% 149,173 $1.0M
MetLife Investment Management, LLC 0.00% Add +17.3% 140,846 $959K
Vanguard Global Advisers, LLC 0.00% Add +14.7% 133,821 $911K
Persistent Asset Partners Ltd 0.29% New 133,411 $909K
VANGUARD ASSET MANAGEMENT, Ltd 0.00% Add +46.6% 132,614 $903K
AQR Capital Management 0.00% Reduce -27.4% 128,764 $877K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +2.5% 127,915 $870K
Mariner, LLC 0.00% New 116,582 $794K
Aquatic Capital Management LLC 0.03% Add +171.5% 108,208 $737K
Legal & General Group Plc 0.00% Add +3.7% 108,207 $737K
Franklin Resources Inc. 0.00% Reduce -1.9% 106,290 $724K
Engineers Gate Manager LP 0.01% New 104,132 $709K
Manufacturers Life Insurance Company, The 0.00% Add +4.8% 104,095 $709K
XTX Topco Ltd 0.01% Add +879.7% 101,195 $689K
Prelude Capital Management, LLC 0.05% New 98,346 $670K
Profund Advisors LLC 0.01% Reduce -40.5% 80,200 $546K
Gsa Capital Partners LLP 0.03% New 72,573 $494K
Police & Firemen's Retirement System of New Jersey 0.00% Add +23.7% 70,719 $482K
New York State Common Retirement Fund 0.00% Add +2.7% 69,300 $472K
Jupiter Topco LLC 0.00% — 69,000 $470K
J. Goldman & Co LP 0.02% Add +99.5% 67,349 $459K
Red Reef Advisors LLC 0.41% No change 65,950 $449K
China Universal Asset Management Co., Ltd. 0.03% Add +35.2% 65,734 $448K
Creative Planning 0.00% Add +6.7% 63,781 $434K
Commonwealth Equity Services, LLC 0.00% Add +5.7% 61,773 $421K
Russell Investments Group, Ltd. 0.00% Add +264.5% 61,705 $420K
OMERS ADMINISTRATION Corp 0.00% New 59,100 $402K
Virtus Investment Advisers, LLC 0.09% Add +21.7% 57,303 $390K
Lanark Financial, Inc. 0.03% Add +1.8% 55,022 $375K
Intech Investment Management LLC 0.00% Add +9.7% 52,618 $358K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -39.1% 49,213 $335K
KLP Kapitalforvaltning As 0.00% Add +63.1% 47,800 $326K
Militia Capital Management LLC 0.06% No change 46,500 $317K
State of New Jersey Common Pension Fund D 0.00% Reduce -0.8% 46,443 $316K
Williams & Novak, LLC 0.20% No change 45,000 $306K
Almanack Investment Partners, LLC. 0.04% New 44,950 $306K
First Manhattan Co. Llc. 0.00% No change 43,500 $296K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% Reduce -23.7% 43,191 $294K
Allianz Asset Management GmbH 0.00% No change 42,400 $289K
ProShare Advisors LLC 0.00% Reduce -7.8% 40,817 $278K
Arizona State Retirement System 0.00% Add +5.3% 39,633 $270K
Prudential Financial Inc. 0.00% Add +15.4% 39,040 $266K
Envestnet Asset Management Inc. 0.00% Add +10.9% 37,314 $254K
Vanguard Investments Australia, Ltd. 0.00% No change 35,887 $244K
Los Angeles Capital Management LLC 0.00% Add +12.8% 32,149 $219K
Cetera Investment Advisers 0.00% Add +11.1% 31,607 $215K
Guggenheim Capital LLC 0.00% Add +79.2% 29,721 $202K
Susquehanna International Group, LLP 0.00% Reduce -76.6% 27,164 $185K
Quadrature Capital Ltd 0.00% Add +9.6% 25,753 $175K
nVerses Capital, LLC 0.26% New 25,152 $171K
State of Wyoming 0.02% New 24,382 $166K
Xponance LLC 0.00% Add +14.2% 22,881 $156K
E Fund Management Co., Ltd. 0.00% Reduce -42.1% 21,814 $149K
Ameritas Investment Partners, Inc. 0.00% Add +23.1% 21,761 $148K
Lee Financial Co 0.02% No change 20,000 $136K
Allstate Corp. 0.00% New 19,447 $132K
Weiss Asset Management LP 0.00% New 19,144 $130K
Aster Capital Management (DIFC) Ltd 0.03% New 18,553 $126K
Principal Financial Group Inc. 0.00% Add +13.3% 18,334 $125K
Vanguard Personalized Indexing Management, LLC 0.00% Add +38.6% 17,979 $122K
Teacher Retirement System of Texas 0.00% Reduce -5.9% 16,736 $114K
Cambridge Investment Research Advisors, Inc. 0.00% Reduce -32.6% 15,075 $103K
Thrivent Financial for Lutherans 0.00% New 14,520 $98K
St Germain D J Co. Inc. 0.00% Add +46.7% 14,133 $96K
Sei Investments Co. 0.00% Reduce -72.9% 13,952 $95K
Bank of Montreal 0.00% No change 13,668 $93K
Captrust Financial Advisors 0.00% New 13,455 $92K
Simplex Trading, LLC 0.00% New 13,371 $91K
CIBC Bancorp USA Inc. 0.00% Add +19.3% 13,262 $90K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -10.0% 12,852 $88K
Ethic Inc. 0.00% Reduce -3.6% 12,512 $85K
Tower Research Capital LLC (TRC) 0.00% Reduce -55.8% 11,530 $79K
Magnetar Financial LLC 0.00% Add +0.6% 11,475 $78K
Neuberger Berman Group LLC 0.00% Add +3.2% 11,170 $76K
Summit Financial, LLC 0.00% Reduce -2.3% 10,888 $74K
Choreo, LLC 0.00% Add +5.7% 10,618 $72K
Capital Investment Advisors, LLC 0.00% No change 10,000 $68K
Osaic Holdings, Inc. 0.00% Add +337.5% 8,838 $60K
Royal Bank of Canada 0.00% Add +3767.0% 7,386 $51K
Allworth Financial LP 0.00% Add +28.2% 6,978 $48K
GF Fund Management Co. LTD. 0.00% Reduce -5.4% 5,797 $39K
Nisa Investment Advisors, LLC 0.00% Add +13.2% 5,780 $39K
Rockefeller Capital Management L.P. 0.00% No change 5,000 $34K
SBI Securities Co., Ltd. 0.00% Add +20333.3% 3,065 $21K
Steward Partners Investment Advisory, LLC 0.00% New 3,000 $20K
Pacer Advisors, Inc. 0.00% New 2,584 $18K
Kemnay Advisory Services Inc. 0.00% New 2,582 $18K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -14.5% 2,099 $14K
Chung Wu Investment Group, LLC 0.01% No change 2,000 $14K
International Assets Investment Management, LLC 0.00% No change 2,000 $13K
Group One Trading LLC 0.00% New 1,939 $13K
Caitong International Asset Management Co., Ltd 0.00% Add +100.3% 1,855 $13K
Jones Financial Companies LLLP 0.00% Add +160.4% 1,461 $9K
US Bancorp \de 0.00% Add +14.4% 1,152 $8K
PNC Financial Services Group, Inc. 0.00% Add +1.0% 1,053 $7K
Sterling Capital Management LLC 0.00% Reduce -40.3% 842 $6K
Federation des caisses Desjardins du Quebec 0.00% Reduce -90.0% 500 $3K
Quarry LP 0.00% New 480 $3K
Larson Financial Group LLC 0.00% Add +266.4% 469 $3K
Optiver Holding B.V. 0.00% Reduce -48.7% 443 $3K
Arax Advisory Partners 0.00% New 360 $2K
Essential Partners LLC 0.00% No change 327 $2K
Parallel Advisors, LLC 0.00% Reduce -2.1% 280 $2K
Signaturefd, LLC 0.00% No change 266 $2K
GAMMA Investing LLC 0.00% Add +71.8% 232 $2K
Rothschild Investment LLC 0.00% No change 170 $1K
Covestor Ltd 0.00% Add +248.2% 94 $1K
Capital Advisors, Ltd. LLC 0.00% No change 79 $1K
EverSource Wealth Advisors, LLC 0.00% No change 141 $960
National Bank of Canada 0.00% New 85 $578
Farther Finance Advisors, LLC 0.00% No change 55 $375
True Wealth Design, LLC 0.00% No change 30 $205
Keating Financial Advisory Services, Inc. 0.00% Add +100.0% 26 $177
IFP Advisors, Inc 0.00% No change 14 $95
Hughes Financial Services, LLC 0.00% New 6 $41

"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.