Xeris Biopharma HoldingsXERS
13F holders, Q1 2026 (March 31)237holders +13
41new positions
29sold out
7famous investors
$5.81avg. 13F price*
At the end of Q1 2026, 237 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 13 from Q4 2025. 41 opened new positions and 29 sold out. The largest holders were BlackRock, Inc. ($75.1M), D. E. Shaw & Co. ($45.2M) and Vanguard Capital Management LLC ($40.5M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Xeris Biopharma Holdings Inc.
- CUSIP
- 98422E103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $23.3M |
| Exits | 29 | $28.9M |
All 13F filers, Q4 2025 → Q1 2026: 16,369,860 shares bought and 10,140,299 shares sold, net +6,229,561 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 237 holders
| BlackRock, Inc. | 0.00% | Add +2.4% | 12,945,785 | $75.1M |
| D. E. Shaw & Co. | 0.04% | Add +2.8% | 7,788,811 | $45.2M |
| Vanguard Capital Management LLC | 0.00% | — | 6,980,882 | $40.5M |
| State Street Corp. | 0.00% | Add +13.2% | 4,658,174 | $27.0M |
| Geode Capital Management, LLC | 0.00% | Add +0.3% | 4,290,629 | $24.9M |
| Qube Research & Technologies Ltd | 0.03% | Add +17.6% | 4,114,425 | $23.9M |
| Rosalind Advisors, Inc. | 7.68% | Add +53.0% | 3,231,700 | $18.7M |
| Nuveen, LLC | 0.00% | Add +3.9% | 2,916,598 | $16.9M |
| Vanguard Portfolio Management LLC | 0.00% | — | 2,665,608 | $15.5M |
| Morgan Stanley | 0.00% | Reduce -5.0% | 2,572,654 | $14.9M |
| Millennium Management | 0.01% | Add +163.8% | 2,265,974 | $13.1M |
| Wellington Management Group LLP | 0.00% | Reduce -5.0% | 2,171,354 | $12.6M |
| Two Sigma Investments, LP | 0.01% | Add +11.1% | 1,924,202 | $11.2M |
| Armistice Capital, LLC | 0.37% | New | 1,909,838 | $11.1M |
| Legal & General Group Plc | 0.00% | Add +36.7% | 1,908,289 | $11.1M |
| Parkman Healthcare Partners LLC | 1.03% | Add +1.8% | 1,721,264 | $10.0M |
| UBS Group AG | 0.00% | Add +173.6% | 1,646,378 | $9.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +2.9% | 1,613,650 | $9.4M |
| Northern Trust Corp. | 0.00% | Add +4.2% | 1,444,617 | $8.4M |
| AQR Capital Management | 0.00% | Add +45.6% | 1,394,376 | $8.1M |
| Voss Capital, LP | 0.46% | Add +273.1% | 1,386,927 | $8.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.1% | 1,359,657 | $7.9M |
| CenterBook Partners LP | 0.39% | Reduce -10.3% | 1,248,621 | $7.2M |
| Kennedy Capital Management LLC | 0.15% | Add +2.2% | 1,240,692 | $7.2M |
| Algert Global LLC | 0.10% | Add +61.0% | 1,156,958 | $6.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 1,133,902 | $6.6M |
| Knott David M Jr | 3.66% | Add +9.3% | 1,060,000 | $6.1M |
| Ishara Investments LP | 6.00% | Add +28.1% | 1,025,000 | $5.9M |
| Granahan Investment Management, LLC | 0.26% | Reduce -24.6% | 921,854 | $5.3M |
| Driehaus Capital Management LLC | 0.04% | Reduce -69.7% | 902,740 | $5.2M |
| Bank of America Corp. | 0.00% | Add +21.8% | 874,397 | $5.1M |
| Federated Hermes, Inc. | 0.01% | Add +0.2% | 856,813 | $5.0M |
| Trexquant Investment LP | 0.04% | Add +290.1% | 833,217 | $4.8M |
| Essex Investment Management Co. LLC | 0.69% | Add +1.8% | 747,769 | $4.3M |
| Jane Street Group, LLC | 0.00% | Add +308.1% | 725,616 | $4.2M |
| Citadel Advisors | 0.00% | Add +66.3% | 681,634 | $4.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.5% | 668,074 | $3.9M |
| Voya Investment Management LLC | 0.00% | Add +36.4% | 625,310 | $3.6M |
| Deutsche Bank AG | 0.00% | Reduce -33.8% | 623,012 | $3.6M |
| Squarepoint Ops LLC | 0.01% | Add +27.3% | 614,550 | $3.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -31.6% | 612,479 | $3.4M |
| Sei Investments Co. | 0.00% | Add +45.0% | 579,210 | $3.4M |
| FMR LLC | 0.00% | Add +16.7% | 513,076 | $3.0M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | Reduce -13.7% | 464,084 | $2.7M |
| Renaissance Technologies | 0.00% | Reduce -26.9% | 452,860 | $2.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.8% | 426,285 | $2.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -61.5% | 407,625 | $2.4M |
| Russell Investments Group, Ltd. | 0.00% | Add +5.3% | 384,195 | $2.2M |
| IHT Wealth Management, LLC | 0.05% | Add +42.9% | 376,476 | $2.2M |
| Canada Pension Plan Investment Board | 0.00% | Reduce -4.0% | 374,800 | $2.2M |
| Voloridge Investment Management, LLC | 0.01% | Reduce -54.4% | 370,116 | $2.1M |
| Swiss National Bank | 0.00% | Add +3.1% | 328,300 | $1.9M |
| State of Wisconsin Investment Board | 0.00% | Reduce -13.7% | 308,546 | $1.8M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +26.3% | 296,431 | $1.7M |
| Janus Henderson Group PLC | 0.00% | Add +322.8% | 295,489 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Add +143.8% | 286,071 | $1.7M |
| Man Group plc | 0.00% | Add +478.6% | 276,422 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1.7% | 262,787 | $1.5M |
| Apella Capital, LLC | 0.02% | Reduce -4.1% | 235,897 | $1.5M |
| Royce & Associates LP | 0.01% | New | 256,087 | $1.5M |
| Rice Hall James & Associates, LLC | 0.08% | New | 251,066 | $1.5M |
| Legato Capital Management LLC | 0.12% | Reduce -1.4% | 234,144 | $1.4M |
| Group One Trading LLC | 0.04% | Add +76.5% | 218,145 | $1.3M |
| T. Rowe Price Associates Inc. | 0.00% | Add +20.5% | 209,034 | $1.2M |
| Principal Financial Group Inc. | 0.00% | Add +38.5% | 208,507 | $1.2M |
| Raymond James Financial Inc. | 0.00% | Reduce -1.5% | 208,273 | $1.2M |
| F/m Investments LLC | 0.08% | New | 207,543 | $1.2M |
| Emerald Mutual Fund Advisers Trust | 0.06% | New | 207,543 | $1.2M |
| Caption Management, LLC | 0.06% | New | 205,000 | $1.2M |
| Commonwealth Equity Services, LLC | 0.00% | Add +2.7% | 203,116 | $1.2M |
| Alliancebernstein L.P. | 0.00% | Add +0.3% | 145,336 | $1.1M |
| Rhumbline Advisers | 0.00% | Add +0.8% | 191,067 | $1.1M |
| Engineers Gate Manager LP | 0.01% | Add +107.9% | 185,911 | $1.1M |
| California State Teachers Retirement System | 0.00% | Add +19.3% | 180,339 | $1.0M |
| HRT Financial LP | 0.00% | Reduce -48.5% | 171,102 | $992K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +78.5% | 161,793 | $938K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.9% | 142,148 | $824K |
| Barclays PLC | 0.00% | Reduce -61.8% | 138,553 | $804K |
| Swiss Life Asset Management Ltd | 0.00% | Add +27.5% | 33,232 | $789K |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -37.7% | 133,760 | $776K |
| Creative Planning | 0.00% | Add +14.4% | 133,285 | $773K |
| Diadema Partners LP | 0.32% | Reduce -22.2% | 132,746 | $770K |
| Quarry LP | 0.15% | Add +56.3% | 125,000 | $725K |
| Globeflex Capital L P | 0.11% | No change | 123,184 | $714K |
| SG Americas Securities, LLC | 0.00% | Add +10.7% | 121,911 | $707K |
| Tudor Investment Corporation | 0.00% | Add +384.1% | 107,414 | $623K |
| Panagora Asset Management Inc. | 0.00% | New | 104,744 | $608K |
| Palo Alto Investors LP | 0.09% | New | 104,410 | $606K |
| WINTON GROUP Ltd | 0.02% | Add +61.4% | 104,240 | $605K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 103,555 | $601K |
| Invesco Ltd. | 0.00% | Reduce -7.9% | 103,294 | $599K |
| Gsa Capital Partners LLP | 0.04% | Add +192.6% | 101,438 | $588K |
| Twinbeech Capital LP | 0.06% | New | 97,200 | $564K |
| Round Rock Advisors LLC | 0.09% | No change | 96,816 | $562K |
| EntryPoint Capital, LLC | 0.16% | Add +41.3% | 96,210 | $558K |
| LPL Financial LLC | 0.00% | Add +10.6% | 93,861 | $544K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +41.9% | 93,302 | $541K |
| Jefferies Financial Group Inc. | 0.01% | No change | 87,800 | $509K |
| Citigroup Inc. | 0.00% | Reduce -11.6% | 87,325 | $506K |
| Thompson Siegel & Walmsley LLC | 0.01% | Reduce -14.4% | 86,320 | $501K |
| Ieq Capital, LLC | 0.00% | Reduce -5.7% | 81,630 | $473K |
| Franklin Resources Inc. | 0.00% | Reduce -33.9% | 80,217 | $465K |
| Magnetar Financial LLC | 0.01% | New | 79,302 | $460K |
| MetLife Investment Management, LLC | 0.00% | New | 76,763 | $445K |
| Vanguard Global Advisers, LLC | 0.00% | — | 76,511 | $444K |
| Western Wealth Management, LLC | 0.02% | No change | 75,675 | $439K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +3.6% | 73,870 | $428K |
| Teachers Retirement System of the State of Kentucky | 0.00% | No change | 72,907 | $423K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +59.0% | 72,804 | $422K |
| Penn Capital Management Company, LLC | 0.03% | Add +43.3% | 68,896 | $400K |
| Integrated Quantitative Investments LLC | 0.07% | No change | 66,170 | $384K |
| Cwm, LLC | 0.00% | Add +15.9% | 64,180 | $372K |
| Wells Fargo & Company | 0.00% | Reduce -65.9% | 58,307 | $338K |
| Prudential Financial Inc. | 0.00% | Reduce -90.8% | 57,139 | $331K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 56,706 | $329K |
| Osaic Holdings, Inc. | 0.00% | Add +4.7% | 54,756 | $318K |
| Weiss Asset Management LP | 0.01% | No change | 50,001 | $290K |
| Palogic Value Management, L.P. | 0.13% | New | 50,000 | $290K |
| Voleon Capital Management LP | 0.01% | New | 46,508 | $270K |
| AlphaCentric Advisors LLC | 0.27% | Add +5.8% | 45,886 | $266K |
| Arizona State Retirement System | 0.00% | Add +0.7% | 45,575 | $264K |
| Cetera Investment Advisers | 0.00% | Add +14.9% | 44,397 | $258K |
| Royal Bank of Canada | 0.00% | Add +12.9% | 43,610 | $253K |
| New York State Common Retirement Fund | 0.00% | No change | 43,422 | $252K |
| Gotham Asset Management | 0.00% | Add +22.1% | 43,257 | $251K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +56.3% | 42,245 | $245K |
| Savvy Advisors, Inc. | 0.01% | Add +2.5% | 41,468 | $241K |
| Profund Advisors LLC | 0.01% | Add +5.6% | 41,133 | $239K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 40,738 | $236K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 40,202 | $233K |
| Stonepine Capital Management, LLC | 0.20% | New | 40,030 | $232K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +19.5% | 37,180 | $225K |
| Virtus Investment Advisers, LLC | 0.06% | Add +2.5% | 38,030 | $221K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 37,970 | $220K |
| DRW Securities, LLC | 0.01% | New | 36,807 | $213K |
| KLP Kapitalforvaltning As | 0.00% | Add +10.2% | 36,800 | $213K |
| Intech Investment Management LLC | 0.00% | Reduce -44.3% | 36,241 | $210K |
| Persistent Asset Partners Ltd | 0.08% | Reduce -21.8% | 35,661 | $207K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.1% | 34,674 | $201K |
| Aigen Investment Management, LP | 0.05% | Add +165.2% | 32,521 | $189K |
| Diversified Trust Co. | 0.00% | No change | 32,062 | $186K |
| HSBC Holdings PLC | 0.00% | New | 31,175 | $183K |
| Quantinno Capital Management LP | 0.00% | Add +25.4% | 30,971 | $180K |
| Fox Run Management, L.L.C. | 0.03% | Add +21.2% | 31,721 | $178K |
| Cerity Partners LLC | 0.00% | Add +3.4% | 30,583 | $177K |
| ProShare Advisors LLC | 0.00% | Reduce -13.9% | 30,480 | $177K |
| Pictet Asset Management Holding SA | 0.00% | Add +29.3% | 29,999 | $174K |
| Quantbot Technologies LP | 0.01% | Reduce -63.9% | 28,064 | $163K |
| Graham Capital Management, L.P. | 0.01% | New | 27,162 | $158K |
| Asset Management Group, Inc. | 0.02% | No change | 26,480 | $154K |
| ExodusPoint Capital Management, LP | 0.00% | New | 25,685 | $149K |
| Janney Montgomery Scott LLC | 0.00% | Add +3.1% | 25,200 | $146K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -28.0% | 24,247 | $141K |
| Mariner, LLC | 0.00% | New | 23,081 | $134K |
| Mirabella Financial Services LLP | 0.01% | New | 22,483 | $130K |
| Teacher Retirement System of Texas | 0.00% | Reduce -11.8% | 21,122 | $123K |
| Dark Forest Capital Management LP | 0.01% | Reduce -59.5% | 21,070 | $122K |
| Entropy Technologies, LP | 0.01% | New | 20,432 | $119K |
| XTX Topco Ltd | 0.00% | New | 20,272 | $118K |
| Campbell & CO Investment Adviser LLC | 0.01% | Reduce -57.8% | 20,027 | $116K |
| Aspiriant, LLC | 0.00% | No change | 20,000 | $116K |
| Van Hulzen Asset Management, LLC | 0.01% | Reduce -4.9% | 19,382 | $112K |
| Kemnay Advisory Services Inc. | 0.02% | Add +116.5% | 18,359 | $106K |
| Victory Capital Management Inc. | 0.00% | Add +2.8% | 18,331 | $106K |
| Tidal Investments LLC | 0.00% | New | 18,159 | $105K |
| Palumbo Wealth Management LLC | 0.03% | Reduce -26.9% | 17,788 | $103K |
| STRS Ohio | 0.00% | Reduce -73.1% | 17,600 | $102K |
| Jacksonville Wealth Management, LLC | 0.07% | No change | 17,000 | $99K |
| Mercer Global Advisors Inc. | 0.00% | New | 16,988 | $99K |
| Neuberger Berman Group LLC | 0.00% | New | 16,725 | $97K |
| Brevan Howard Capital Management LP | 0.00% | Reduce -83.0% | 15,753 | $91K |
| Landscape Capital Management, L.L.C. | 0.01% | No change | 15,709 | $91K |
| Captrust Financial Advisors | 0.00% | Add +25.4% | 14,815 | $86K |
| CIBC Bancorp USA Inc. | 0.00% | — | 14,673 | $85K |
| Xponance LLC | 0.00% | Add +18.3% | 14,325 | $83K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | No change | 14,192 | $82K |
| Chicago Partners Investment Group LLC | 0.00% | New | 13,493 | $81K |
| R Squared Ltd | 0.04% | New | 13,802 | $80K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.00% | Reduce -15.1% | 13,650 | $79K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 12,827 | $74K |
| Pallas Capital Advisors LLC | 0.00% | Add +1.1% | 11,121 | $65K |
| IMC-Chicago, LLC | 0.00% | New | 10,881 | $63K |
| Brooklyn Investment Group | 0.00% | Reduce -13.6% | 10,534 | $61K |
| State of Wyoming | 0.01% | Reduce -75.5% | 10,420 | $60K |
| Scientech Research LLC | 0.05% | New | 10,414 | $60K |
| Kingsview Wealth Management, LLC | 0.00% | No change | 10,000 | $58K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -9.3% | 9,742 | $57K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 8,655 | $50K |
| State of Alaska, Department of Revenue | 0.00% | No change | 8,457 | $49K |
| Truvestments Capital LLC | 0.01% | No change | 8,118 | $47K |
| Jones Financial Companies LLLP | 0.00% | Add +8.8% | 6,207 | $34K |
| KBC Group NV | 0.00% | New | 4,573 | $27K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.8% | 3,710 | $22K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +32.0% | 3,105 | $18K |
| Rockefeller Capital Management L.P. | 0.00% | Add +399.0% | 2,964 | $17K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -1.1% | 2,789 | $16K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -4.0% | 2,469 | $15K |
| Allworth Financial LP | 0.00% | New | 2,315 | $13K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 2,204 | $13K |
| Creative Financial Designs Inc. | 0.00% | No change | 2,200 | $13K |
| Arax Advisory Partners | 0.00% | Add +23.6% | 2,017 | $12K |
| MAI Capital Management | 0.00% | Add +7288.9% | 1,995 | $12K |
| SBI Securities Co., Ltd. | 0.00% | No change | 1,907 | $11K |
| Webster Bank, N. A. | 0.00% | Reduce -36.7% | 1,900 | $11K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -42.5% | 1,620 | $9K |
| Fortitude Family Office, LLC | 0.00% | No change | 1,553 | $9K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,500 | $9K |
| Sound Income Strategies, LLC | 0.00% | Add +8.5% | 1,247 | $8K |
| Essential Partners LLC | 0.00% | No change | 1,288 | $7K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +67.3% | 1,134 | $7K |
| PNC Financial Services Group, Inc. | 0.00% | Add +163.9% | 1,053 | $6K |
| Sterling Capital Management LLC | 0.00% | No change | 1,020 | $6K |
| True Wealth Design, LLC | 0.00% | No change | 1,011 | $6K |
| Activest Wealth Management | 0.00% | No change | 1,000 | $6K |
| Advisory Services Network, LLC | 0.00% | New | 1,000 | $6K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -95.6% | 791 | $5K |
| Rothschild Investment LLC | 0.00% | Add +69.0% | 759 | $4K |
| Tsfg, LLC | 0.00% | No change | 708 | $4K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 687 | $4K |
| Signaturefd, LLC | 0.00% | Reduce -12.4% | 631 | $4K |
| Fifth Third Bancorp | 0.00% | New | 280 | $2K |
| Basecamp Wealth Advisors LLC | 0.00% | New | 259 | $2K |
| Smartleaf Asset Management LLC | 0.00% | No change | 225 | $1K |
| Spurstone Advisory Services, LLC | 0.02% | No change | 200 | $1K |
| Parkside Financial Bank & Trust | 0.00% | No change | 155 | $899 |
| Larson Financial Group LLC | 0.00% | New | 104 | $603 |
| GAMMA Investing LLC | 0.00% | Add +334.8% | 100 | $580 |
| Sunbelt Securities, Inc. | 0.00% | No change | 81 | $470 |
| SJS Investment Consulting Inc. | 0.00% | Add +231.6% | 63 | $366 |
| Versant Capital Management, Inc | 0.00% | New | 49 | $284 |
| Steigerwald, Gordon & Koch Inc. | 0.00% | No change | 37 | $215 |
| Atlantic Private Wealth, LLC | 0.00% | No change | 30 | $174 |
| IFP Advisors, Inc | 0.00% | Reduce -95.7% | 6 | $35 |
| JPL Wealth Management, LLC | 0.00% | New | 6 | $35 |
| Hughes Financial Services, LLC | 0.00% | New | 4 | $23 |
| Bessemer Group Inc. | 0.00% | Reduce -91.2% | 6 | $0 |
| Covestor Ltd | 0.00% | Reduce -88.6% | 20 | $0 |
"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.