Blueprint MedicinesBPMC
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 346 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 27 from Q3 2024. 42 opened new positions and 27 sold out. The largest holders were BlackRock, Inc. ($599.1M), Vanguard Group Inc. ($590.9M) and T. Rowe Price Associates Inc. ($495.3M). 9 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Blueprint Medicines Corp.
- CUSIP
- 09627Y109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 42 | $197.1M |
| Exits | 27 | $34.5M |
All 13F filers, Q3 2024 → Q4 2024: 7,735,463 shares bought and 6,248,707 shares sold, net +1,486,756 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 346 holders
| BlackRock, Inc. | 0.01% | Reduce -3.5% | 6,869,327 | $599.1M |
| Vanguard Group Inc. | 0.01% | Add +1.4% | 6,774,884 | $590.9M |
| T. Rowe Price Associates Inc. | 0.06% | Add +5.4% | 5,679,089 | $495.3M |
| Wellington Management Group LLP | 0.07% | Add +8.0% | 4,281,364 | $373.4M |
| State Street Corp. | 0.01% | Reduce -9.6% | 2,500,207 | $218.1M |
| FMR LLC | 0.01% | Reduce -50.2% | 2,247,679 | $196.0M |
| William Blair Investment Management, LLC | 0.41% | Add +16.1% | 1,944,695 | $169.6M |
| Geode Capital Management, LLC | 0.01% | Add +0.7% | 1,490,101 | $130.0M |
| Macquarie Group Ltd. | 0.13% | Reduce -0.4% | 1,258,976 | $109.8M |
| Avoro Capital Advisors LLC | 1.46% | New | 1,185,000 | $103.4M |
| Pictet Asset Management Holding SA | 0.11% | Add +1.5% | 1,183,682 | $103.2M |
| JPMorgan Chase & Co. | 0.01% | Reduce -5.4% | 1,155,634 | $100.8M |
| Alliancebernstein L.P. | 0.03% | Reduce -6.5% | 1,138,022 | $99.3M |
| Rock Springs Capital Management LP | 3.65% | Add +42.7% | 1,096,899 | $95.7M |
| Goldman Sachs Group Inc. | 0.02% | Add +45.0% | 1,046,535 | $91.3M |
| Invesco Ltd. | 0.02% | Add +6.7% | 960,437 | $83.8M |
| Hood River Capital Management LLC | 1.13% | Add +30.9% | 879,932 | $76.7M |
| Eventide Asset Management, LLC | 1.37% | Add +147.3% | 862,285 | $75.2M |
| American Century Companies Inc. | 0.04% | Add +3.0% | 839,203 | $73.2M |
| Alkeon Capital Management LLC | 0.40% | Add +11.4% | 800,628 | $69.8M |
| Millennium Management | 0.06% | Add +19.2% | 737,364 | $64.3M |
| Norges Bank | 0.01% | Add +17.9% | 711,164 | $62.0M |
| T. Rowe Price Investment Management, Inc. | 0.04% | Reduce -6.9% | 697,027 | $60.8M |
| Citadel Advisors | 0.05% | Add +734.8% | 649,958 | $56.7M |
| Jacobs Levy Equity Management, Inc. | 0.20% | Add +30.8% | 648,660 | $56.6M |
| Polar Capital Holdings Plc | 0.31% | Reduce -28.6% | 626,379 | $54.6M |
| Northern Trust Corp. | 0.01% | Add +9.5% | 608,392 | $53.1M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +1.2% | 604,397 | $52.7M |
| Brown Advisory Inc. | 0.06% | Reduce -2.5% | 578,780 | $50.5M |
| Woodline Partners LP | 0.32% | Add +19.1% | 540,192 | $47.1M |
| Morgan Stanley | 0.00% | Reduce -6.0% | 504,343 | $44.0M |
| Clearbridge Investments, LLC | 0.03% | Add +1.9% | 490,779 | $42.8M |
| Nuveen Asset Management, LLC | 0.01% | Add +49.2% | 419,190 | $36.6M |
| Emerald Advisers, LLC | 1.41% | Add +10.9% | 416,866 | $36.4M |
| Jane Street Group, LLC | 0.06% | Add +115.8% | 408,222 | $35.6M |
| Bank of America Corp. | 0.00% | Reduce -4.0% | 395,031 | $34.5M |
| D. E. Shaw & Co. | 0.04% | Add +41.5% | 361,801 | $31.6M |
| Jennison Associates LLC | 0.02% | New | 360,208 | $31.4M |
| Qube Research & Technologies Ltd | 0.05% | Add +26.7% | 350,090 | $30.5M |
| Ameriprise Financial Inc. | 0.01% | Add +4.2% | 338,115 | $29.5M |
| Lord, Abbett & Co. LLC | 0.10% | Reduce -71.6% | 335,043 | $29.2M |
| Casdin Capital, LLC | 1.90% | No change | 326,378 | $28.5M |
| Fisher Asset Management | 0.01% | Reduce -3.7% | 323,040 | $28.2M |
| TD Asset Management Inc | 0.02% | Add +13.9% | 303,500 | $26.5M |
| Bank of New York Mellon Corp | 0.00% | Add +2.4% | 303,432 | $26.5M |
| Catalio Capital Management, LP | 5.43% | — | 284,654 | $24.8M |
| Ensign Peak Advisors, Inc | 0.04% | Reduce -15.6% | 275,424 | $24.0M |
| Integral Health Asset Management, LLC | 2.12% | Reduce -5.2% | 275,000 | $24.0M |
| Massachusetts Financial Services Co. | 0.01% | Add +7.0% | 269,990 | $23.5M |
| Emerald Mutual Fund Advisers Trust | 1.43% | Reduce -6.8% | 268,978 | $23.5M |
| Squarepoint Ops LLC | 0.06% | Add +18.4% | 265,420 | $23.1M |
| Deutsche Bank AG | 0.01% | Add +9.4% | 261,363 | $22.8M |
| Raymond James Financial Inc. | 0.01% | — | 241,966 | $21.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +5.3% | 239,946 | $20.9M |
| Voloridge Investment Management, LLC | 0.07% | Reduce -25.7% | 213,697 | $18.6M |
| Voya Investment Management LLC | 0.02% | Add +11.8% | 205,391 | $17.9M |
| Logos Global Management LP | 2.04% | New | 200,000 | $17.4M |
| UBS Group AG | 0.00% | Add +68.0% | 197,460 | $17.2M |
| Barclays PLC | 0.01% | Add +10.5% | 189,127 | $16.5M |
| Avidity Partners Management LP | 1.54% | Reduce -43.9% | 176,600 | $15.4M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +17.7% | 176,484 | $15.4M |
| Novo Holdings A/S | 0.92% | No change | 175,000 | $15.3M |
| Ikarian Capital, LLC | 4.22% | Add +99.3% | 169,374 | $14.8M |
| Point72 Asset Management | 0.04% | New | 166,418 | $14.5M |
| Marshall Wace, LLP | 0.02% | Reduce -51.5% | 161,882 | $14.1M |
| Federated Hermes, Inc. | 0.03% | Add +1.9% | 156,284 | $13.6M |
| DAFNA Capital Management LLC | 3.36% | Add +23.0% | 149,763 | $13.1M |
| AQR Capital Management | 0.02% | Add +26.9% | 144,693 | $12.6M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.06% | Add +2680.9% | 142,717 | $12.4M |
| Granahan Investment Management, LLC | 0.52% | Add +8.2% | 141,890 | $12.4M |
| Segall Bryant & Hamill, LLC | 0.17% | Reduce -1.3% | 139,743 | $12.2M |
| Susquehanna International Group, LLP | 0.02% | Add +10.0% | 136,211 | $11.9M |
| Aquilo Capital Management, LLC | 19.36% | Add +4.0% | 129,600 | $11.3M |
| Trexquant Investment LP | 0.13% | Add +7.2% | 127,098 | $11.1M |
| Renaissance Technologies | 0.02% | Reduce -27.6% | 126,300 | $11.0M |
| Russell Investments Group, Ltd. | 0.02% | Add +15.5% | 125,902 | $11.0M |
| Swiss National Bank | 0.01% | Add +7.2% | 124,600 | $10.9M |
| Algert Global LLC | 0.23% | Add +21.6% | 112,172 | $9.8M |
| Orion Investment Co | 3.78% | Add +0.1% | 108,670 | $9.5M |
| Frontier Capital Management Co. LLC | 0.09% | Add +401.6% | 105,130 | $9.2M |
| Man Group plc | 0.03% | Reduce -80.0% | 103,919 | $9.1M |
| Balyasny Asset Management L.P. | 0.02% | Add +331.5% | 102,486 | $8.9M |
| Prudential Financial Inc. | 0.01% | Add +11.9% | 100,538 | $8.8M |
| Peregrine Capital Management LLC | 0.26% | Add +1.8% | 98,812 | $8.6M |
| Assenagon Asset Management S.A. | 0.02% | Reduce -3.3% | 97,353 | $8.5M |
| Cinctive Capital Management LP | 0.45% | Add +29.2% | 96,048 | $8.4M |
| Citigroup Inc. | 0.01% | Reduce -33.6% | 95,182 | $8.3M |
| Legal & General Group Plc | 0.00% | Add +3.8% | 94,516 | $8.2M |
| Capital Fund Management S.A. | 0.08% | Add +25.9% | 89,905 | $7.8M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -24.0% | 88,891 | $7.8M |
| Rhumbline Advisers | 0.01% | Reduce -1.5% | 86,531 | $7.5M |
| BIT Capital GmbH | 0.60% | Add +4.4% | 78,921 | $6.9M |
| California Public Employees Retirement System | 0.00% | Reduce -24.0% | 78,450 | $6.8M |
| Oberweis Asset Management Inc./ | 0.31% | New | 75,000 | $6.5M |
| EFG Asset Management (North America) Corp. | 0.88% | Add +120.5% | 74,300 | $6.5M |
| Panagora Asset Management Inc. | 0.03% | Reduce -26.2% | 71,416 | $6.2M |
| Sei Investments Co. | 0.01% | Add +10.0% | 70,384 | $6.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.02% | No change | 69,887 | $6.1M |
| First Turn Management, LLC | 1.05% | Reduce -62.5% | 67,143 | $5.9M |
| Prosight Management, LP | 1.64% | Add +42.3% | 67,000 | $5.8M |
| Neuberger Berman Group LLC | 0.00% | Add +3.9% | 66,395 | $5.8M |
| Diadema Partners LP | 6.31% | — | 64,193 | $5.6M |
| California State Teachers Retirement System | 0.01% | Add +4.8% | 59,259 | $5.2M |
| Susquehanna Fundamental Investments, LLC | 0.08% | — | 56,245 | $4.9M |
| Ally Bridge Group (NY) LLC | 4.18% | Reduce -47.3% | 55,892 | $4.9M |
| First Trust Advisors LP | 0.00% | Reduce -2.0% | 53,705 | $4.7M |
| Hillsdale Investment Management Inc. | 0.22% | Add +0.6% | 50,830 | $4.4M |
| Boothbay Fund Management, LLC | 0.14% | Add +99.0% | 49,487 | $4.3M |
| Aquatic Capital Management LLC | 0.11% | Add +11.7% | 47,602 | $4.2M |
| Jefferies Financial Group Inc. | 0.05% | Reduce -4.1% | 47,500 | $4.1M |
| Group One Trading LLC | 0.14% | Reduce -6.5% | 47,194 | $4.1M |
| Essex Investment Management Co. LLC | 0.72% | Add +29.0% | 45,736 | $4.0M |
| Axiom Investors LLC | 0.03% | Reduce -4.2% | 43,904 | $3.8M |
| NBW Capital LLC | 0.71% | Add +25.2% | 43,886 | $3.8M |
| Point72 Europe (London) LLP | 0.22% | New | 43,568 | $3.8M |
| PFM Health Sciences, LP | 0.29% | New | 42,840 | $3.7M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +1.4% | 42,855 | $3.7M |
| State of Wisconsin Investment Board | 0.01% | Reduce -11.1% | 42,057 | $3.7M |
| Wells Fargo & Company | 0.00% | Reduce -38.9% | 40,732 | $3.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +3.1% | 40,208 | $3.5M |
| Fieldview Capital Management, LLC | 0.53% | — | 39,089 | $3.4M |
| Dana Investment Advisors, Inc. | 0.11% | Add +6.2% | 39,074 | $3.4M |
| Schroder Investment Management Group | 0.00% | Reduce -60.1% | 38,434 | $3.3M |
| MetLife Investment Management, LLC | 0.02% | Add +5.0% | 38,099 | $3.3M |
| Franklin Resources Inc. | 0.00% | Reduce -0.5% | 36,586 | $3.2M |
| Verition Fund Management LLC | 0.02% | Add +259.4% | 35,074 | $3.1M |
| Zimmer Partners, LP | 0.05% | Add +59.5% | 33,650 | $2.9M |
| Mutual of America Capital Management LLC | 0.03% | Reduce -0.1% | 32,116 | $2.8M |
| Envestnet Asset Management Inc. | 0.00% | Add +13.1% | 32,115 | $2.8M |
| Engineers Gate Manager LP | 0.05% | Add +120.1% | 32,047 | $2.8M |
| Exome Asset Management LLC | 2.09% | Reduce -13.3% | 31,800 | $2.8M |
| Corebridge Financial, Inc. | 0.01% | Reduce -6.0% | 31,613 | $2.8M |
| Intech Investment Management LLC | 0.03% | Add +70.5% | 31,571 | $2.8M |
| F/m Investments LLC | 0.10% | New | 31,313 | $2.7M |
| Janus Henderson Group PLC | 0.00% | No change | 28,749 | $2.5M |
| Walleye Capital LLC | 0.03% | Add +758.4% | 27,890 | $2.4M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 25,883 | $2.3M |
| Erste Asset Management GmbH | 0.03% | No change | 25,100 | $2.2M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +12.2% | 25,626 | $2.2M |
| Fred Alger Management, LLC | 0.01% | Reduce -22.6% | 25,623 | $2.2M |
| Graham Capital Management, L.P. | 0.11% | Add +48.8% | 25,260 | $2.2M |
| Synovus Financial Corp. | 0.03% | Add +2.0% | 24,528 | $2.1M |
| Granite Investment Partners, LLC | 0.09% | New | 23,255 | $2.0M |
| Tema ETFs LLC | 0.81% | — | 22,474 | $2.0M |
| Pathstone Holdings, LLC | 0.01% | Add +8.8% | 21,900 | $1.9M |
| ProShare Advisors LLC | 0.00% | Add +33.9% | 20,915 | $1.8M |
| Edgestream Partners, L.P. | 0.08% | Reduce -63.7% | 20,395 | $1.8M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.05% | Reduce -9.5% | 20,133 | $1.8M |
| HSBC Holdings PLC | 0.00% | Reduce -37.1% | 20,019 | $1.7M |
| Canada Pension Plan Investment Board | 0.00% | New | 19,800 | $1.7M |
| New York State Common Retirement Fund | 0.00% | No change | 19,520 | $1.7M |
| Creative Planning | 0.00% | Add +47.6% | 19,481 | $1.7M |
| Teacher Retirement System of Texas | 0.01% | Add +25.7% | 18,760 | $1.6M |
| Handelsbanken Fonder AB | 0.01% | Add +19.2% | 18,651 | $1.6M |
| Bayesian Capital Management, LP | 0.20% | New | 18,579 | $1.6M |
| Arizona State Retirement System | 0.01% | Add +7.2% | 18,353 | $1.6M |
| Brevan Howard Capital Management LP | 0.04% | Add +48.5% | 17,751 | $1.5M |
| Profund Advisors LLC | 0.06% | Reduce -24.3% | 17,746 | $1.5M |
| Nomura Asset Management Co. Ltd. | 0.00% | Reduce -21.5% | 17,713 | $1.5M |
| NEOS Investment Management LLC | 0.04% | Reduce -4.6% | 17,103 | $1.5M |
| Twin Tree Management, LP | 0.04% | Add +42.5% | 17,028 | $1.5M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 16,520 | $1.4M |
| Torray Investment Partners LLC | 0.21% | Add +1.1% | 16,499 | $1.4M |
| Principal Financial Group Inc. | 0.00% | Add +46.6% | 16,183 | $1.4M |
| Victory Capital Management Inc. | 0.00% | Reduce -91.6% | 16,023 | $1.4M |
| Martingale Asset Management L P | 0.03% | Add +2.5% | 15,993 | $1.4M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +17.1% | 15,936 | $1.4M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,172 | $1.3M |
| Jain Global LLC | 0.04% | — | 14,974 | $1.3M |
| Oak Ridge Investments LLC | 0.10% | Reduce -6.2% | 14,197 | $1.2M |
| Mackenzie Financial Corp. | 0.00% | Add +99.7% | 14,177 | $1.2M |
| Allianz Asset Management GmbH | 0.00% | Add +91.7% | 13,800 | $1.2M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | — | 13,577 | $1.2M |
| China Universal Asset Management Co., Ltd. | 0.11% | Add +10.6% | 13,470 | $1.2M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -77.8% | 13,200 | $1.2M |
| Guggenheim Capital LLC | 0.01% | Reduce -22.1% | 13,139 | $1.1M |
| Comerica Bank | 0.00% | Add +411.5% | 13,115 | $1.1M |
| KLP Kapitalforvaltning As | 0.01% | — | 12,900 | $1.1M |
| Jackson Creek Investment Advisors LLC | 0.34% | Reduce -3.0% | 12,770 | $1.1M |
| Knights of Columbus Asset Advisors LLC | 0.07% | New | 12,652 | $1.1M |
| Sectoral Asset Management Inc. | 0.73% | Reduce -15.8% | 12,560 | $1.1M |
| Persistent Asset Partners Ltd | 0.93% | — | 9,693 | $1.1M |
| BNP Paribas Financial Markets | 0.00% | Reduce -43.3% | 12,485 | $1.1M |
| Los Angeles Capital Management LLC | 0.00% | No change | 11,179 | $975K |
| XTX Topco Ltd | 0.08% | Add +406.6% | 11,146 | $972K |
| Pitcairn Co. | 0.05% | Add +2.8% | 10,608 | $925K |
| Fox Run Management, L.L.C. | 0.16% | Add +262.7% | 10,264 | $895K |
| Ieq Capital, LLC | 0.01% | New | 10,163 | $886K |
| Fiduciary Trust Co | 0.01% | No change | 10,152 | $885K |
| Campbell & CO Investment Adviser LLC | 0.07% | Reduce -48.8% | 10,060 | $877K |
| S&co Inc. | 0.06% | No change | 10,000 | $872K |
| US Bancorp \de | 0.00% | Reduce -16.6% | 9,983 | $871K |
| Royal Bank of Canada | 0.00% | Reduce -47.5% | 8,932 | $779K |
| Dark Forest Capital Management LP | 0.11% | Reduce -17.1% | 8,579 | $748K |
| Prelude Capital Management, LLC | 0.06% | Reduce -16.3% | 8,552 | $746K |
| Henshaw Capital LLC | 0.03% | No change | 8,475 | $739K |
| Captrust Financial Advisors | 0.00% | Reduce -53.5% | 8,331 | $727K |
| Tudor Investment Corporation | 0.01% | New | 8,100 | $706K |
| PEAK6 LLC | 0.03% | — | 7,999 | $698K |
| LPL Financial LLC | 0.00% | Reduce -12.4% | 7,957 | $694K |
| Wolverine Trading, LLC | 0.02% | Add +33.2% | 7,811 | $678K |
| Nebula Research & Development LLC | 0.08% | Add +18.8% | 7,759 | $677K |
| Diversified Trust Co. | 0.02% | Reduce -52.7% | 7,418 | $647K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +903.5% | 7,265 | $634K |
| DNB Asset Management AS | 0.00% | Reduce -18.0% | 7,145 | $623K |
| Cetera Investment Advisers | 0.00% | Reduce -3.4% | 6,861 | $598K |
| Ameritas Investment Partners, Inc. | 0.02% | Add +4.4% | 6,652 | $580K |
| Simplex Trading, LLC | 0.02% | New | 6,608 | $576K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,512 | $568K |
| STRS Ohio | 0.00% | Add +4.8% | 6,500 | $567K |
| E Fund Management Co., Ltd. | 0.03% | Reduce -15.8% | 6,318 | $551K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -17.8% | 6,220 | $541K |
| HRT Financial LP | 0.00% | Reduce -64.9% | 5,996 | $522K |
| Cibc World Markets Corp. | 0.00% | New | 5,950 | $519K |
| Advisors Asset Management, Inc. | 0.01% | Add +16.5% | 5,886 | $513K |
| Pallas Capital Advisors LLC | 0.02% | Add +1.3% | 5,729 | $500K |
| Mraz, Amerine & Associates, Inc. | 0.08% | Reduce -7.5% | 5,346 | $466K |
| Alpha DNA Investment Management LLC | 0.24% | New | 5,098 | $445K |
| De Lisle Partners LLP | 0.06% | No change | 5,000 | $436K |
| Values First Advisors, Inc. | 0.24% | Add +277.9% | 4,970 | $433K |
| Xponance LLC | 0.00% | Add +12.3% | 4,781 | $417K |
| Kennedy Capital Management LLC | 0.01% | Add +19.6% | 4,564 | $398K |
| Aigen Investment Management, LP | 0.07% | New | 4,485 | $391K |
| Gilbert & Cook, Inc. | 0.05% | Reduce -0.4% | 4,354 | $380K |
| SG Americas Securities, LLC | 0.00% | Add +69.7% | 4,277 | $373K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 4,000 | $349K |
| Citizens Financial Group Inc. | 0.01% | Add +0.1% | 3,922 | $342K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Reduce -17.1% | 3,807 | $332K |
| Virtus Advisers, LLC | 0.13% | Add +22.0% | 3,777 | $329K |
| Stephens Inc. | 0.00% | New | 3,684 | $321K |
| Bridgefront Capital, LLC | 0.11% | Reduce -40.6% | 3,603 | $314K |
| Gotham Asset Management | 0.00% | New | 3,545 | $309K |
| NewEdge Wealth, LLC | 0.01% | Add +2.0% | 3,446 | $301K |
| Intrust Bank NA | 0.03% | Add +12.5% | 3,439 | $300K |
| Sherbrooke Park Advisers LLC | 0.09% | Add +8.4% | 3,374 | $294K |
| Cerity Partners LLC | 0.00% | New | 3,298 | $291K |
| Cwm, LLC | 0.00% | Add +75.3% | 3,279 | $286K |
| Allspring Global Investments Holdings, LLC | 0.00% | Add +0.5% | 3,222 | $281K |
| Mariner, LLC | 0.00% | Add +1.4% | 3,203 | $279K |
| Bellevue Group AG | 0.01% | No change | 3,200 | $279K |
| O'shaughnessy Asset Management, LLC | 0.00% | Reduce -10.5% | 3,193 | $278K |
| Vinva Investment Management Ltd | 0.01% | New | 1,950 | $272K |
| Corton Capital Inc. | 0.16% | Add +1.6% | 3,107 | $271K |
| PDT Partners, LLC | 0.02% | New | 3,098 | $270K |
| Magnetar Financial LLC | 0.01% | New | 3,084 | $269K |
| Fifth Third Bancorp | 0.00% | Add +207.5% | 3,075 | $268K |
| Clarus Wealth Advisors | 0.13% | Reduce -0.7% | 2,573 | $266K |
| Clear Harbor Asset Management, LLC | 0.02% | Reduce -2.6% | 3,019 | $263K |
| Point72 (DIFC) Ltd | 0.02% | New | 2,934 | $256K |
| Bayforest Capital Ltd | 0.32% | — | 2,885 | $252K |
| Sanctuary Advisors, LLC | 0.00% | Add +0.8% | 2,160 | $246K |
| Birchview Capital, LP | 0.19% | No change | 2,700 | $235K |
| KBC Group NV | 0.00% | Add +63.9% | 2,625 | $229K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -22.1% | 2,610 | $228K |
| EntryPoint Capital, LLC | 0.09% | Reduce -39.7% | 2,586 | $226K |
| Truist Financial Corp. | 0.00% | New | 2,530 | $221K |
| ExodusPoint Capital Management, LP | 0.00% | Reduce -25.8% | 2,512 | $219K |
| Dynamic Technology Lab Private Ltd | 0.03% | New | 2,436 | $212K |
| Syon Capital LLC | 0.02% | New | 2,347 | $205K |
| Point72 Hong Kong Ltd | 0.01% | New | 2,218 | $193K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.6% | 2,117 | $189K |
| Amalgamated Bank | 0.00% | No change | 2,154 | $188K |
| Exchange Traded Concepts, LLC | 0.00% | Reduce -1.1% | 2,009 | $175K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -1.9% | 1,857 | $162K |
| Walleye Trading LLC | 0.00% | New | 1,731 | $151K |
| PNC Financial Services Group, Inc. | 0.00% | Add +31.9% | 1,650 | $144K |
| CI Investments Inc. | 0.00% | Add +11.5% | 1,641 | $143K |
| Venturi Wealth Management, LLC | 0.01% | New | 1,500 | $131K |
| Lazard Asset Management LLC | 0.00% | Reduce -86.4% | 1,378 | $118K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,334 | $116K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.03% | New | 1,220 | $106K |
| Van Eck Associates Corp. | 0.00% | Add +48.2% | 1,116 | $97K |
| Asset Management One Co., Ltd. | 0.00% | New | 989 | $88K |
| Covestor Ltd | 0.05% | Add +62.7% | 973 | $85K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -5.0% | 854 | $74K |
| C M Bidwell & Associates Ltd. | 0.04% | Add +1.3% | 838 | $73K |
| Thematics Asset Management | 0.00% | New | 826 | $72K |
| Compass Wealth Management LLC | 0.02% | No change | 750 | $65K |
| Headlands Technologies LLC | 0.01% | New | 749 | $65K |
| Leonteq Securities AG | 0.01% | New | 717 | $63K |
| R Squared Ltd | 0.05% | — | 590 | $51K |
| Osaic Holdings, Inc. | 0.00% | Reduce -71.1% | 1,260 | $49K |
| Natixis | 0.00% | Reduce -16.1% | 465 | $41K |
| Coppell Advisory Solutions LLC | 0.01% | Add +6.0% | 462 | $40K |
| Tortoise Investment Management, LLC | 0.00% | No change | 396 | $35K |
| Empirical Asset Management, LLC | 0.01% | New | 26,921 | $27K |
| Parallel Advisors, LLC | 0.00% | Add +6.3% | 304 | $27K |
| Lindbrook Capital, LLC | 0.00% | Add +0.3% | 300 | $26K |
| Danske Bank A/S | 0.00% | Reduce -72.7% | 300 | $26K |
| Huntington National Bank | 0.00% | Add +28.7% | 296 | $26K |
| Empowered Funds, LLC | 0.00% | New | 254 | $22K |
| Bessemer Group Inc. | 0.00% | Reduce -76.3% | 237 | $21K |
| GAMMA Investing LLC | 0.00% | Add +27.8% | 239 | $21K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -11.4% | 210 | $18K |
| Crowley Wealth Management, Inc. | 0.02% | — | 200 | $17K |
| Harbour Investments, Inc. | 0.00% | No change | 200 | $17K |
| Smartleaf Asset Management LLC | 0.00% | Add +14.7% | 195 | $17K |
| Caitong International Asset Management Co., Ltd | 0.02% | — | 192 | $17K |
| Signaturefd, LLC | 0.00% | Add +6.5% | 180 | $16K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +478.6% | 162 | $14K |
| Global Retirement Partners, LLC | 0.00% | Reduce -8.6% | 160 | $14K |
| Rise Advisors, LLC | 0.01% | No change | 156 | $14K |
| True Wealth Design, LLC | 0.01% | Add +11.1% | 150 | $13K |
| UMB Bank, n.a. | 0.00% | Reduce -11.2% | 127 | $11K |
| AdvisorNet Financial, Inc | 0.00% | Reduce -11.2% | 119 | $10K |
| Blue Trust, Inc. | 0.00% | Add +73.8% | 113 | $10K |
| Spire Wealth Management | 0.00% | New | 110 | $10K |
| Clearstead Trust, LLC | 0.00% | No change | 101 | $9K |
| Farmers & Merchants Investments Inc. | 0.00% | No change | 100 | $9K |
| Truvestments Capital LLC | 0.00% | No change | 98 | $9K |
| AlphaQuest LLC | 0.00% | Reduce -93.9% | 95 | $8K |
| Parkside Financial Bank & Trust | 0.00% | New | 84 | $7K |
| Quantbot Technologies LP | 0.00% | Reduce -93.5% | 76 | $7K |
| Versant Capital Management, Inc | 0.00% | Add +630.0% | 73 | $6K |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 70 | $6K |
| Rothschild Investment LLC | 0.00% | Add +8.3% | 65 | $6K |
| Sterling Capital Management LLC | 0.00% | Add +1.6% | 65 | $6K |
| Clearstead Advisors, LLC | 0.00% | No change | 63 | $5K |
| Quent Capital, LLC | 0.00% | No change | 61 | $5K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 58 | $5K |
| Arax Advisory Partners | 0.00% | Reduce -12.3% | 50 | $4K |
| Private Wealth Management Group, LLC | 0.00% | No change | 49 | $4K |
| Meeder Asset Management Inc. | 0.00% | Add +4.3% | 48 | $4K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -2.1% | 46 | $4K |
| Picton Mahoney Asset Management | 0.00% | Add +60.0% | 40 | $4K |
| WPG Advisers, LLC | 0.00% | — | 32 | $3K |
| Principal Securities, Inc. | 0.00% | Add +31.6% | 25 | $2K |
| CENTRAL TRUST Co | 0.00% | No change | 23 | $2K |
| First Horizon Advisors, Inc. | 0.00% | Add +40.0% | 21 | $2K |
| Wolff Wiese Magana LLC | 0.00% | No change | 19 | $2K |
| Allworth Financial LP | 0.00% | Add +250.0% | 14 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +16.7% | 14 | $1K |
| Assetmark, Inc. | 0.00% | Add +133.3% | 14 | $1K |
| Riggs Asset Managment Co. Inc. | 0.00% | No change | 12 | $1K |
| Transamerica Financial Advisors, LLC | 0.00% | No change | 1 | $1K |
| Bokf, NA | 0.00% | New | 8 | $699 |
| Cassady Schiller Wealth Management, LLC | 0.00% | New | 8 | $698 |
| Wilmington Savings Fund Society, FSB | 0.00% | No change | 5 | $436 |
| SBI Securities Co., Ltd. | 0.00% | — | 5 | $436 |
| J.Safra Asset Management Corp | 0.00% | Reduce -95.8% | 5 | $434 |
| NewEdge Advisors, LLC | 0.00% | No change | 4 | $349 |
| IFP Advisors, Inc | 0.00% | Reduce -98.8% | 4 | $349 |
| Quadrant Capital Group LLC | 0.00% | Reduce -92.5% | 3 | $262 |
| Lanark Financial, Inc. | 0.02% | — | 2 | $235 |
| Innovative Advisory Group, LLC | 0.00% | — | 1 | $87 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 3 | $0 |
"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.