Blueprint MedicinesBPMC

13F holders, Q4 2024 (December 31)
346holders +27
42new positions
27sold out
9famous investors
$87.19avg. 13F price*

At the end of Q4 2024, 346 institutions reported holding Blueprint Medicines Corp. (BPMC) in their 13F filings, up 27 from Q3 2024. 42 opened new positions and 27 sold out. The largest holders were BlackRock, Inc. ($599.1M), Vanguard Group Inc. ($590.9M) and T. Rowe Price Associates Inc. ($495.3M). 9 famous investors held it, including Israel Englander (0.1% of Millennium Management's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Blueprint Medicines Corp.
CUSIP
09627Y109
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 281Q1 2024Q2 2024: 305Q2 2024Q3 2024: 319Q3 2024Q4 2024: 346Q4 2024Q1 2025: 353Q1 2025Q2 2025: 356Q2 2025Q3 2025: 5Q3 2025Q4 2025: 2Q4 2025Q1 2026: 2Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions42$197.1M
Exits27$34.5M

All 13F filers, Q3 2024 → Q4 2024: 7,735,463 shares bought and 6,248,707 shares sold, net +1,486,756 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 346 holders

BlackRock, Inc. 0.01% Reduce -3.5% 6,869,327 $599.1M
Vanguard Group Inc. 0.01% Add +1.4% 6,774,884 $590.9M
T. Rowe Price Associates Inc. 0.06% Add +5.4% 5,679,089 $495.3M
Wellington Management Group LLP 0.07% Add +8.0% 4,281,364 $373.4M
State Street Corp. 0.01% Reduce -9.6% 2,500,207 $218.1M
FMR LLC 0.01% Reduce -50.2% 2,247,679 $196.0M
William Blair Investment Management, LLC 0.41% Add +16.1% 1,944,695 $169.6M
Geode Capital Management, LLC 0.01% Add +0.7% 1,490,101 $130.0M
Macquarie Group Ltd. 0.13% Reduce -0.4% 1,258,976 $109.8M
Avoro Capital Advisors LLC 1.46% New 1,185,000 $103.4M
Pictet Asset Management Holding SA 0.11% Add +1.5% 1,183,682 $103.2M
JPMorgan Chase & Co. 0.01% Reduce -5.4% 1,155,634 $100.8M
Alliancebernstein L.P. 0.03% Reduce -6.5% 1,138,022 $99.3M
Rock Springs Capital Management LP 3.65% Add +42.7% 1,096,899 $95.7M
Goldman Sachs Group Inc. 0.02% Add +45.0% 1,046,535 $91.3M
Invesco Ltd. 0.02% Add +6.7% 960,437 $83.8M
Hood River Capital Management LLC 1.13% Add +30.9% 879,932 $76.7M
Eventide Asset Management, LLC 1.37% Add +147.3% 862,285 $75.2M
American Century Companies Inc. 0.04% Add +3.0% 839,203 $73.2M
Alkeon Capital Management LLC 0.40% Add +11.4% 800,628 $69.8M
Millennium Management 0.06% Add +19.2% 737,364 $64.3M
Norges Bank 0.01% Add +17.9% 711,164 $62.0M
T. Rowe Price Investment Management, Inc. 0.04% Reduce -6.9% 697,027 $60.8M
Citadel Advisors 0.05% Add +734.8% 649,958 $56.7M
Jacobs Levy Equity Management, Inc. 0.20% Add +30.8% 648,660 $56.6M
Polar Capital Holdings Plc 0.31% Reduce -28.6% 626,379 $54.6M
Northern Trust Corp. 0.01% Add +9.5% 608,392 $53.1M
Charles Schwab Investment Management Inc. 0.01% Add +1.2% 604,397 $52.7M
Brown Advisory Inc. 0.06% Reduce -2.5% 578,780 $50.5M
Woodline Partners LP 0.32% Add +19.1% 540,192 $47.1M
Morgan Stanley 0.00% Reduce -6.0% 504,343 $44.0M
Clearbridge Investments, LLC 0.03% Add +1.9% 490,779 $42.8M
Nuveen Asset Management, LLC 0.01% Add +49.2% 419,190 $36.6M
Emerald Advisers, LLC 1.41% Add +10.9% 416,866 $36.4M
Jane Street Group, LLC 0.06% Add +115.8% 408,222 $35.6M
Bank of America Corp. 0.00% Reduce -4.0% 395,031 $34.5M
D. E. Shaw & Co. 0.04% Add +41.5% 361,801 $31.6M
Jennison Associates LLC 0.02% New 360,208 $31.4M
Qube Research & Technologies Ltd 0.05% Add +26.7% 350,090 $30.5M
Ameriprise Financial Inc. 0.01% Add +4.2% 338,115 $29.5M
Lord, Abbett & Co. LLC 0.10% Reduce -71.6% 335,043 $29.2M
Casdin Capital, LLC 1.90% No change 326,378 $28.5M
Fisher Asset Management 0.01% Reduce -3.7% 323,040 $28.2M
TD Asset Management Inc 0.02% Add +13.9% 303,500 $26.5M
Bank of New York Mellon Corp 0.00% Add +2.4% 303,432 $26.5M
Catalio Capital Management, LP 5.43% — 284,654 $24.8M
Ensign Peak Advisors, Inc 0.04% Reduce -15.6% 275,424 $24.0M
Integral Health Asset Management, LLC 2.12% Reduce -5.2% 275,000 $24.0M
Massachusetts Financial Services Co. 0.01% Add +7.0% 269,990 $23.5M
Emerald Mutual Fund Advisers Trust 1.43% Reduce -6.8% 268,978 $23.5M
Squarepoint Ops LLC 0.06% Add +18.4% 265,420 $23.1M
Deutsche Bank AG 0.01% Add +9.4% 261,363 $22.8M
Raymond James Financial Inc. 0.01% — 241,966 $21.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +5.3% 239,946 $20.9M
Voloridge Investment Management, LLC 0.07% Reduce -25.7% 213,697 $18.6M
Voya Investment Management LLC 0.02% Add +11.8% 205,391 $17.9M
Logos Global Management LP 2.04% New 200,000 $17.4M
UBS Group AG 0.00% Add +68.0% 197,460 $17.2M
Barclays PLC 0.01% Add +10.5% 189,127 $16.5M
Avidity Partners Management LP 1.54% Reduce -43.9% 176,600 $15.4M
Manufacturers Life Insurance Company, The 0.01% Add +17.7% 176,484 $15.4M
Novo Holdings A/S 0.92% No change 175,000 $15.3M
Ikarian Capital, LLC 4.22% Add +99.3% 169,374 $14.8M
Point72 Asset Management 0.04% New 166,418 $14.5M
Marshall Wace, LLP 0.02% Reduce -51.5% 161,882 $14.1M
Federated Hermes, Inc. 0.03% Add +1.9% 156,284 $13.6M
DAFNA Capital Management LLC 3.36% Add +23.0% 149,763 $13.1M
AQR Capital Management 0.02% Add +26.9% 144,693 $12.6M
Connor, Clark & Lunn Investment Management Ltd. 0.06% Add +2680.9% 142,717 $12.4M
Granahan Investment Management, LLC 0.52% Add +8.2% 141,890 $12.4M
Segall Bryant & Hamill, LLC 0.17% Reduce -1.3% 139,743 $12.2M
Susquehanna International Group, LLP 0.02% Add +10.0% 136,211 $11.9M
Aquilo Capital Management, LLC 19.36% Add +4.0% 129,600 $11.3M
Trexquant Investment LP 0.13% Add +7.2% 127,098 $11.1M
Renaissance Technologies 0.02% Reduce -27.6% 126,300 $11.0M
Russell Investments Group, Ltd. 0.02% Add +15.5% 125,902 $11.0M
Swiss National Bank 0.01% Add +7.2% 124,600 $10.9M
Algert Global LLC 0.23% Add +21.6% 112,172 $9.8M
Orion Investment Co 3.78% Add +0.1% 108,670 $9.5M
Frontier Capital Management Co. LLC 0.09% Add +401.6% 105,130 $9.2M
Man Group plc 0.03% Reduce -80.0% 103,919 $9.1M
Balyasny Asset Management L.P. 0.02% Add +331.5% 102,486 $8.9M
Prudential Financial Inc. 0.01% Add +11.9% 100,538 $8.8M
Peregrine Capital Management LLC 0.26% Add +1.8% 98,812 $8.6M
Assenagon Asset Management S.A. 0.02% Reduce -3.3% 97,353 $8.5M
Cinctive Capital Management LP 0.45% Add +29.2% 96,048 $8.4M
Citigroup Inc. 0.01% Reduce -33.6% 95,182 $8.3M
Legal & General Group Plc 0.00% Add +3.8% 94,516 $8.2M
Capital Fund Management S.A. 0.08% Add +25.9% 89,905 $7.8M
Rafferty Asset Management, LLC 0.03% Reduce -24.0% 88,891 $7.8M
Rhumbline Advisers 0.01% Reduce -1.5% 86,531 $7.5M
BIT Capital GmbH 0.60% Add +4.4% 78,921 $6.9M
California Public Employees Retirement System 0.00% Reduce -24.0% 78,450 $6.8M
Oberweis Asset Management Inc./ 0.31% New 75,000 $6.5M
EFG Asset Management (North America) Corp. 0.88% Add +120.5% 74,300 $6.5M
Panagora Asset Management Inc. 0.03% Reduce -26.2% 71,416 $6.2M
Sei Investments Co. 0.01% Add +10.0% 70,384 $6.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.02% No change 69,887 $6.1M
First Turn Management, LLC 1.05% Reduce -62.5% 67,143 $5.9M
Prosight Management, LP 1.64% Add +42.3% 67,000 $5.8M
Neuberger Berman Group LLC 0.00% Add +3.9% 66,395 $5.8M
Diadema Partners LP 6.31% — 64,193 $5.6M
California State Teachers Retirement System 0.01% Add +4.8% 59,259 $5.2M
Susquehanna Fundamental Investments, LLC 0.08% — 56,245 $4.9M
Ally Bridge Group (NY) LLC 4.18% Reduce -47.3% 55,892 $4.9M
First Trust Advisors LP 0.00% Reduce -2.0% 53,705 $4.7M
Hillsdale Investment Management Inc. 0.22% Add +0.6% 50,830 $4.4M
Boothbay Fund Management, LLC 0.14% Add +99.0% 49,487 $4.3M
Aquatic Capital Management LLC 0.11% Add +11.7% 47,602 $4.2M
Jefferies Financial Group Inc. 0.05% Reduce -4.1% 47,500 $4.1M
Group One Trading LLC 0.14% Reduce -6.5% 47,194 $4.1M
Essex Investment Management Co. LLC 0.72% Add +29.0% 45,736 $4.0M
Axiom Investors LLC 0.03% Reduce -4.2% 43,904 $3.8M
NBW Capital LLC 0.71% Add +25.2% 43,886 $3.8M
Point72 Europe (London) LLP 0.22% New 43,568 $3.8M
PFM Health Sciences, LP 0.29% New 42,840 $3.7M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% Add +1.4% 42,855 $3.7M
State of Wisconsin Investment Board 0.01% Reduce -11.1% 42,057 $3.7M
Wells Fargo & Company 0.00% Reduce -38.9% 40,732 $3.6M
Dimensional Fund Advisors LP 0.00% Add +3.1% 40,208 $3.5M
Fieldview Capital Management, LLC 0.53% — 39,089 $3.4M
Dana Investment Advisors, Inc. 0.11% Add +6.2% 39,074 $3.4M
Schroder Investment Management Group 0.00% Reduce -60.1% 38,434 $3.3M
MetLife Investment Management, LLC 0.02% Add +5.0% 38,099 $3.3M
Franklin Resources Inc. 0.00% Reduce -0.5% 36,586 $3.2M
Verition Fund Management LLC 0.02% Add +259.4% 35,074 $3.1M
Zimmer Partners, LP 0.05% Add +59.5% 33,650 $2.9M
Mutual of America Capital Management LLC 0.03% Reduce -0.1% 32,116 $2.8M
Envestnet Asset Management Inc. 0.00% Add +13.1% 32,115 $2.8M
Engineers Gate Manager LP 0.05% Add +120.1% 32,047 $2.8M
Exome Asset Management LLC 2.09% Reduce -13.3% 31,800 $2.8M
Corebridge Financial, Inc. 0.01% Reduce -6.0% 31,613 $2.8M
Intech Investment Management LLC 0.03% Add +70.5% 31,571 $2.8M
F/m Investments LLC 0.10% New 31,313 $2.7M
Janus Henderson Group PLC 0.00% No change 28,749 $2.5M
Walleye Capital LLC 0.03% Add +758.4% 27,890 $2.4M
DekaBank Deutsche Girozentrale 0.00% No change 25,883 $2.3M
Erste Asset Management GmbH 0.03% No change 25,100 $2.2M
State of New Jersey Common Pension Fund D 0.01% Add +12.2% 25,626 $2.2M
Fred Alger Management, LLC 0.01% Reduce -22.6% 25,623 $2.2M
Graham Capital Management, L.P. 0.11% Add +48.8% 25,260 $2.2M
Synovus Financial Corp. 0.03% Add +2.0% 24,528 $2.1M
Granite Investment Partners, LLC 0.09% New 23,255 $2.0M
Tema ETFs LLC 0.81% — 22,474 $2.0M
Pathstone Holdings, LLC 0.01% Add +8.8% 21,900 $1.9M
ProShare Advisors LLC 0.00% Add +33.9% 20,915 $1.8M
Edgestream Partners, L.P. 0.08% Reduce -63.7% 20,395 $1.8M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% Reduce -9.5% 20,133 $1.8M
HSBC Holdings PLC 0.00% Reduce -37.1% 20,019 $1.7M
Canada Pension Plan Investment Board 0.00% New 19,800 $1.7M
New York State Common Retirement Fund 0.00% No change 19,520 $1.7M
Creative Planning 0.00% Add +47.6% 19,481 $1.7M
Teacher Retirement System of Texas 0.01% Add +25.7% 18,760 $1.6M
Handelsbanken Fonder AB 0.01% Add +19.2% 18,651 $1.6M
Bayesian Capital Management, LP 0.20% New 18,579 $1.6M
Arizona State Retirement System 0.01% Add +7.2% 18,353 $1.6M
Brevan Howard Capital Management LP 0.04% Add +48.5% 17,751 $1.5M
Profund Advisors LLC 0.06% Reduce -24.3% 17,746 $1.5M
Nomura Asset Management Co. Ltd. 0.00% Reduce -21.5% 17,713 $1.5M
NEOS Investment Management LLC 0.04% Reduce -4.6% 17,103 $1.5M
Twin Tree Management, LP 0.04% Add +42.5% 17,028 $1.5M
Teachers Retirement System of the State of Kentucky 0.01% No change 16,520 $1.4M
Torray Investment Partners LLC 0.21% Add +1.1% 16,499 $1.4M
Principal Financial Group Inc. 0.00% Add +46.6% 16,183 $1.4M
Victory Capital Management Inc. 0.00% Reduce -91.6% 16,023 $1.4M
Martingale Asset Management L P 0.03% Add +2.5% 15,993 $1.4M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +17.1% 15,936 $1.4M
State Board of Administration of Florida Retirement System 0.00% No change 15,172 $1.3M
Jain Global LLC 0.04% — 14,974 $1.3M
Oak Ridge Investments LLC 0.10% Reduce -6.2% 14,197 $1.2M
Mackenzie Financial Corp. 0.00% Add +99.7% 14,177 $1.2M
Allianz Asset Management GmbH 0.00% Add +91.7% 13,800 $1.2M
Police & Firemen's Retirement System of New Jersey 0.01% — 13,577 $1.2M
China Universal Asset Management Co., Ltd. 0.11% Add +10.6% 13,470 $1.2M
Schonfeld Strategic Advisors LLC 0.01% Reduce -77.8% 13,200 $1.2M
Guggenheim Capital LLC 0.01% Reduce -22.1% 13,139 $1.1M
Comerica Bank 0.00% Add +411.5% 13,115 $1.1M
KLP Kapitalforvaltning As 0.01% — 12,900 $1.1M
Jackson Creek Investment Advisors LLC 0.34% Reduce -3.0% 12,770 $1.1M
Knights of Columbus Asset Advisors LLC 0.07% New 12,652 $1.1M
Sectoral Asset Management Inc. 0.73% Reduce -15.8% 12,560 $1.1M
Persistent Asset Partners Ltd 0.93% — 9,693 $1.1M
BNP Paribas Financial Markets 0.00% Reduce -43.3% 12,485 $1.1M
Los Angeles Capital Management LLC 0.00% No change 11,179 $975K
XTX Topco Ltd 0.08% Add +406.6% 11,146 $972K
Pitcairn Co. 0.05% Add +2.8% 10,608 $925K
Fox Run Management, L.L.C. 0.16% Add +262.7% 10,264 $895K
Ieq Capital, LLC 0.01% New 10,163 $886K
Fiduciary Trust Co 0.01% No change 10,152 $885K
Campbell & CO Investment Adviser LLC 0.07% Reduce -48.8% 10,060 $877K
S&co Inc. 0.06% No change 10,000 $872K
US Bancorp \de 0.00% Reduce -16.6% 9,983 $871K
Royal Bank of Canada 0.00% Reduce -47.5% 8,932 $779K
Dark Forest Capital Management LP 0.11% Reduce -17.1% 8,579 $748K
Prelude Capital Management, LLC 0.06% Reduce -16.3% 8,552 $746K
Henshaw Capital LLC 0.03% No change 8,475 $739K
Captrust Financial Advisors 0.00% Reduce -53.5% 8,331 $727K
Tudor Investment Corporation 0.01% New 8,100 $706K
PEAK6 LLC 0.03% — 7,999 $698K
LPL Financial LLC 0.00% Reduce -12.4% 7,957 $694K
Wolverine Trading, LLC 0.02% Add +33.2% 7,811 $678K
Nebula Research & Development LLC 0.08% Add +18.8% 7,759 $677K
Diversified Trust Co. 0.02% Reduce -52.7% 7,418 $647K
Tower Research Capital LLC (TRC) 0.01% Add +903.5% 7,265 $634K
DNB Asset Management AS 0.00% Reduce -18.0% 7,145 $623K
Cetera Investment Advisers 0.00% Reduce -3.4% 6,861 $598K
Ameritas Investment Partners, Inc. 0.02% Add +4.4% 6,652 $580K
Simplex Trading, LLC 0.02% New 6,608 $576K
Public Employees Retirement Association of Colorado 0.00% No change 6,512 $568K
STRS Ohio 0.00% Add +4.8% 6,500 $567K
E Fund Management Co., Ltd. 0.03% Reduce -15.8% 6,318 $551K
CANADA LIFE ASSURANCE Co 0.00% Reduce -17.8% 6,220 $541K
HRT Financial LP 0.00% Reduce -64.9% 5,996 $522K
Cibc World Markets Corp. 0.00% New 5,950 $519K
Advisors Asset Management, Inc. 0.01% Add +16.5% 5,886 $513K
Pallas Capital Advisors LLC 0.02% Add +1.3% 5,729 $500K
Mraz, Amerine & Associates, Inc. 0.08% Reduce -7.5% 5,346 $466K
Alpha DNA Investment Management LLC 0.24% New 5,098 $445K
De Lisle Partners LLP 0.06% No change 5,000 $436K
Values First Advisors, Inc. 0.24% Add +277.9% 4,970 $433K
Xponance LLC 0.00% Add +12.3% 4,781 $417K
Kennedy Capital Management LLC 0.01% Add +19.6% 4,564 $398K
Aigen Investment Management, LP 0.07% New 4,485 $391K
Gilbert & Cook, Inc. 0.05% Reduce -0.4% 4,354 $380K
SG Americas Securities, LLC 0.00% Add +69.7% 4,277 $373K
Farallon Capital Management, L.L.C. 0.00% No change 4,000 $349K
Citizens Financial Group Inc. 0.01% Add +0.1% 3,922 $342K
Vanguard Personalized Indexing Management, LLC 0.01% Reduce -17.1% 3,807 $332K
Virtus Advisers, LLC 0.13% Add +22.0% 3,777 $329K
Stephens Inc. 0.00% New 3,684 $321K
Bridgefront Capital, LLC 0.11% Reduce -40.6% 3,603 $314K
Gotham Asset Management 0.00% New 3,545 $309K
NewEdge Wealth, LLC 0.01% Add +2.0% 3,446 $301K
Intrust Bank NA 0.03% Add +12.5% 3,439 $300K
Sherbrooke Park Advisers LLC 0.09% Add +8.4% 3,374 $294K
Cerity Partners LLC 0.00% New 3,298 $291K
Cwm, LLC 0.00% Add +75.3% 3,279 $286K
Allspring Global Investments Holdings, LLC 0.00% Add +0.5% 3,222 $281K
Mariner, LLC 0.00% Add +1.4% 3,203 $279K
Bellevue Group AG 0.01% No change 3,200 $279K
O'shaughnessy Asset Management, LLC 0.00% Reduce -10.5% 3,193 $278K
Vinva Investment Management Ltd 0.01% New 1,950 $272K
Corton Capital Inc. 0.16% Add +1.6% 3,107 $271K
PDT Partners, LLC 0.02% New 3,098 $270K
Magnetar Financial LLC 0.01% New 3,084 $269K
Fifth Third Bancorp 0.00% Add +207.5% 3,075 $268K
Clarus Wealth Advisors 0.13% Reduce -0.7% 2,573 $266K
Clear Harbor Asset Management, LLC 0.02% Reduce -2.6% 3,019 $263K
Point72 (DIFC) Ltd 0.02% New 2,934 $256K
Bayforest Capital Ltd 0.32% — 2,885 $252K
Sanctuary Advisors, LLC 0.00% Add +0.8% 2,160 $246K
Birchview Capital, LP 0.19% No change 2,700 $235K
KBC Group NV 0.00% Add +63.9% 2,625 $229K
Steward Partners Investment Advisory, LLC 0.00% Reduce -22.1% 2,610 $228K
EntryPoint Capital, LLC 0.09% Reduce -39.7% 2,586 $226K
Truist Financial Corp. 0.00% New 2,530 $221K
ExodusPoint Capital Management, LP 0.00% Reduce -25.8% 2,512 $219K
Dynamic Technology Lab Private Ltd 0.03% New 2,436 $212K
Syon Capital LLC 0.02% New 2,347 $205K
Point72 Hong Kong Ltd 0.01% New 2,218 $193K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.6% 2,117 $189K
Amalgamated Bank 0.00% No change 2,154 $188K
Exchange Traded Concepts, LLC 0.00% Reduce -1.1% 2,009 $175K
Nisa Investment Advisors, LLC 0.00% Reduce -1.9% 1,857 $162K
Walleye Trading LLC 0.00% New 1,731 $151K
PNC Financial Services Group, Inc. 0.00% Add +31.9% 1,650 $144K
CI Investments Inc. 0.00% Add +11.5% 1,641 $143K
Venturi Wealth Management, LLC 0.01% New 1,500 $131K
Lazard Asset Management LLC 0.00% Reduce -86.4% 1,378 $118K
GF Fund Management Co. LTD. 0.00% — 1,334 $116K
Point72 Asia (Singapore) Pte. Ltd. 0.03% New 1,220 $106K
Van Eck Associates Corp. 0.00% Add +48.2% 1,116 $97K
Asset Management One Co., Ltd. 0.00% New 989 $88K
Covestor Ltd 0.05% Add +62.7% 973 $85K
Northwestern Mutual Wealth Management Co. 0.00% Reduce -5.0% 854 $74K
C M Bidwell & Associates Ltd. 0.04% Add +1.3% 838 $73K
Thematics Asset Management 0.00% New 826 $72K
Compass Wealth Management LLC 0.02% No change 750 $65K
Headlands Technologies LLC 0.01% New 749 $65K
Leonteq Securities AG 0.01% New 717 $63K
R Squared Ltd 0.05% — 590 $51K
Osaic Holdings, Inc. 0.00% Reduce -71.1% 1,260 $49K
Natixis 0.00% Reduce -16.1% 465 $41K
Coppell Advisory Solutions LLC 0.01% Add +6.0% 462 $40K
Tortoise Investment Management, LLC 0.00% No change 396 $35K
Empirical Asset Management, LLC 0.01% New 26,921 $27K
Parallel Advisors, LLC 0.00% Add +6.3% 304 $27K
Lindbrook Capital, LLC 0.00% Add +0.3% 300 $26K
Danske Bank A/S 0.00% Reduce -72.7% 300 $26K
Huntington National Bank 0.00% Add +28.7% 296 $26K
Empowered Funds, LLC 0.00% New 254 $22K
Bessemer Group Inc. 0.00% Reduce -76.3% 237 $21K
GAMMA Investing LLC 0.00% Add +27.8% 239 $21K
Daiwa Securities Group Inc. 0.00% Reduce -11.4% 210 $18K
Crowley Wealth Management, Inc. 0.02% — 200 $17K
Harbour Investments, Inc. 0.00% No change 200 $17K
Smartleaf Asset Management LLC 0.00% Add +14.7% 195 $17K
Caitong International Asset Management Co., Ltd 0.02% — 192 $17K
Signaturefd, LLC 0.00% Add +6.5% 180 $16K
EverSource Wealth Advisors, LLC 0.00% Add +478.6% 162 $14K
Global Retirement Partners, LLC 0.00% Reduce -8.6% 160 $14K
Rise Advisors, LLC 0.01% No change 156 $14K
True Wealth Design, LLC 0.01% Add +11.1% 150 $13K
UMB Bank, n.a. 0.00% Reduce -11.2% 127 $11K
AdvisorNet Financial, Inc 0.00% Reduce -11.2% 119 $10K
Blue Trust, Inc. 0.00% Add +73.8% 113 $10K
Spire Wealth Management 0.00% New 110 $10K
Clearstead Trust, LLC 0.00% No change 101 $9K
Farmers & Merchants Investments Inc. 0.00% No change 100 $9K
Truvestments Capital LLC 0.00% No change 98 $9K
AlphaQuest LLC 0.00% Reduce -93.9% 95 $8K
Parkside Financial Bank & Trust 0.00% New 84 $7K
Quantbot Technologies LP 0.00% Reduce -93.5% 76 $7K
Versant Capital Management, Inc 0.00% Add +630.0% 73 $6K
Cullen/Frost Bankers, Inc. 0.00% No change 70 $6K
Rothschild Investment LLC 0.00% Add +8.3% 65 $6K
Sterling Capital Management LLC 0.00% Add +1.6% 65 $6K
Clearstead Advisors, LLC 0.00% No change 63 $5K
Quent Capital, LLC 0.00% No change 61 $5K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% No change 58 $5K
Arax Advisory Partners 0.00% Reduce -12.3% 50 $4K
Private Wealth Management Group, LLC 0.00% No change 49 $4K
Meeder Asset Management Inc. 0.00% Add +4.3% 48 $4K
Farther Finance Advisors, LLC 0.00% Reduce -2.1% 46 $4K
Picton Mahoney Asset Management 0.00% Add +60.0% 40 $4K
WPG Advisers, LLC 0.00% — 32 $3K
Principal Securities, Inc. 0.00% Add +31.6% 25 $2K
CENTRAL TRUST Co 0.00% No change 23 $2K
First Horizon Advisors, Inc. 0.00% Add +40.0% 21 $2K
Wolff Wiese Magana LLC 0.00% No change 19 $2K
Allworth Financial LP 0.00% Add +250.0% 14 $2K
MassMutual Private Wealth & Trust, FSB 0.00% Add +16.7% 14 $1K
Assetmark, Inc. 0.00% Add +133.3% 14 $1K
Riggs Asset Managment Co. Inc. 0.00% No change 12 $1K
Transamerica Financial Advisors, LLC 0.00% No change 1 $1K
Bokf, NA 0.00% New 8 $699
Cassady Schiller Wealth Management, LLC 0.00% New 8 $698
Wilmington Savings Fund Society, FSB 0.00% No change 5 $436
SBI Securities Co., Ltd. 0.00% — 5 $436
J.Safra Asset Management Corp 0.00% Reduce -95.8% 5 $434
NewEdge Advisors, LLC 0.00% No change 4 $349
IFP Advisors, Inc 0.00% Reduce -98.8% 4 $349
Quadrant Capital Group LLC 0.00% Reduce -92.5% 3 $262
Lanark Financial, Inc. 0.02% — 2 $235
Innovative Advisory Group, LLC 0.00% — 1 $87
Capital Advisors, Ltd. LLC 0.00% No change 3 $0

"% of holder's portfolio" is BPMC's weight in each manager's 13F, not the share of Blueprint Medicines Corp. the manager owns.