Lexicon PharmaceuticalsLXRX

13F holders, Q3 2024 (September 30)
137holders +10
23new positions
14sold out
3famous investors
$1.57avg. 13F price*

At the end of Q3 2024, 137 institutions reported holding Lexicon Pharmaceuticals Inc. (LXRX) in their 13F filings, up 10 from Q2 2024. 23 opened new positions and 14 sold out. The largest holders were Artal Group S.A. ($213.8M), FMR LLC ($78.3M) and Siren, L.L.C. ($61.1M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Lexicon Pharmaceuticals Inc.
CUSIP
528872302
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 118Q1 2024Q2 2024: 127Q2 2024Q3 2024: 137Q3 2024Q4 2024: 127Q4 2024Q1 2025: 127Q1 2025Q2 2025: 123Q2 2025Q3 2025: 123Q3 2025Q4 2025: 125Q4 2025Q1 2026: 136Q1 2026Q2 2026: 149Q2 2026

Total Exit/New Position Q2 2024 → Q3 2024

InstitutionsTotal Value
New Positions23$4.9M
Exits14$3.7M

All 13F filers, Q2 2024 → Q3 2024: 25,169,186 shares bought and 54,661,819 shares sold, net −29,492,633 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 137 holders

Artal Group S.A. 8.98% Reduce -22.2% 136,180,481 $213.8M
FMR LLC 0.00% Add +28.9% 49,867,042 $78.3M
Siren, L.L.C. 3.06% — 38,918,903 $61.1M
Orbimed Advisors LLC 0.32% Add +88.6% 11,024,000 $17.3M
BlackRock, Inc. 0.00% — 10,133,014 $15.9M
Vanguard Group Inc. 0.00% Add +5.4% 8,091,098 $12.7M
Geode Capital Management, LLC 0.00% Add +8.4% 3,523,971 $5.5M
State Street Corp. 0.00% Add +6.8% 2,471,215 $3.9M
NEA Management Company, LLC 0.20% No change 2,382,286 $3.7M
Ameriprise Financial Inc. 0.00% Add +11.2% 2,327,110 $3.7M
Nantahala Capital Management, LLC 0.30% No change 2,304,150 $3.6M
Schonfeld Strategic Advisors LLC 0.02% Add +229.4% 1,882,600 $3.0M
Pinnacle Associates Ltd. 0.04% Add +0.9% 1,730,821 $2.6M
Charles Schwab Investment Management Inc. 0.00% Add +4.3% 1,417,295 $2.2M
Millennium Management 0.00% Add +134.2% 1,398,876 $2.2M
Point72 Asset Management 0.01% Reduce -70.2% 1,230,050 $1.9M
Woodline Partners LP 0.02% New 1,211,924 $1.9M
Northern Trust Corp. 0.00% Add +14.7% 1,144,031 $1.8M
Nuveen Asset Management, LLC 0.00% Add +410.4% 1,103,840 $1.7M
Braidwell LP 0.05% Reduce -90.3% 801,584 $1.3M
Wellington Management Group LLP 0.00% Reduce -0.8% 732,747 $1.2M
Hennion & Walsh Asset Management, Inc. 0.05% Add +34.7% 731,138 $1.1M
Marshall Wace, LLP 0.00% Reduce -51.8% 574,150 $901K
Knott David M Jr 0.28% New 500,000 $785K
BBR Partners, LLC 0.06% Add +74.1% 470,000 $738K
Morgan Stanley 0.00% Add +28.5% 454,977 $714K
Goldman Sachs Group Inc. 0.00% Add +7.5% 401,291 $630K
Swiss National Bank 0.00% New 317,500 $498K
Bank of New York Mellon Corp 0.00% Reduce -21.7% 314,780 $494K
Alliancebernstein L.P. 0.00% No change 273,041 $429K
Two Sigma Investments, LP 0.00% Add +969.5% 204,879 $322K
Barclays PLC 0.00% Add +391.6% 193,873 $304K
Squarepoint Ops LLC 0.00% New 188,842 $296K
Virtus Advisers, LLC 0.13% No change 179,972 $283K
Deerfield Management Company, L.P. 0.00% New 156,860 $246K
California State Teachers Retirement System 0.00% Add +1706.7% 150,300 $236K
Rhumbline Advisers 0.00% Reduce -4.5% 145,939 $229K
UBS Group AG 0.00% Reduce -13.1% 139,992 $220K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 120,387 $189K
T. Rowe Price Associates Inc. 0.00% No change 117,179 $184K
Legal & General Group Plc 0.00% Add +871.6% 111,403 $175K
Commonwealth Equity Services, LLC 0.00% Add +7.5% 108,734 $171K
Bank of America Corp. 0.00% Add +22.8% 107,088 $168K
Tang Capital Management LLC 0.01% New 100,000 $157K
Compagnie Lombard Odier SCmA 0.00% Add +6.4% 100,000 $157K
Citadel Advisors 0.00% Reduce -95.9% 98,624 $155K
Citigroup Inc. 0.00% Add +170.9% 89,745 $141K
JPMorgan Chase & Co. 0.00% Reduce -0.8% 89,700 $141K
Susquehanna International Group, LLP 0.00% Reduce -23.3% 87,501 $137K
Jane Street Group, LLC 0.00% Reduce -34.3% 85,361 $134K
XTX Topco Ltd 0.01% New 80,423 $126K
Atom Investors LP 0.01% New 77,733 $122K
Wells Fargo & Company 0.00% Add +67.7% 76,489 $120K
Dimensional Fund Advisors LP 0.00% No change 76,086 $119K
Intech Investment Management LLC 0.00% New 73,440 $115K
Bank of Montreal 0.00% No change 70,001 $112K
China Universal Asset Management Co., Ltd. 0.01% Add +63.7% 69,527 $109K
Deutsche Bank AG 0.00% Add +107.1% 66,043 $104K
Invesco Ltd. 0.00% Add +8.9% 65,074 $102K
LPL Financial LLC 0.00% Add +3.2% 63,035 $99K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +33.4% 62,958 $99K
Corebridge Financial, Inc. 0.00% Reduce -0.6% 61,391 $96K
Pathstone Holdings, LLC 0.00% Reduce -1.8% 58,959 $93K
Acadian Asset Management LLC 0.00% New 58,007 $91K
MetLife Investment Management, LLC 0.00% No change 55,182 $87K
Stifel Financial Corp. 0.00% Add +1.1% 51,997 $82K
CIBC Private Wealth Group LLC 0.00% Add +500000.0% 50,010 $79K
Russell Investments Group, Ltd. 0.00% Reduce -7.5% 49,100 $77K
Manufacturers Life Insurance Company, The 0.00% Reduce -3.8% 48,048 $75K
Arizona State Retirement System 0.00% New 46,840 $74K
SG Americas Securities, LLC 0.00% Add +107.6% 46,090 $72K
CANADA LIFE ASSURANCE Co 0.00% New 46,013 $72K
Victory Capital Management Inc. 0.00% Reduce -2.3% 44,307 $70K
KWB Wealth 0.01% No change 40,640 $68K
ProShare Advisors LLC 0.00% Add +24.0% 43,056 $68K
Wedbush Securities Inc. 0.00% No change 40,850 $64K
Teacher Retirement System of Texas 0.00% New 40,800 $64K
Voya Investment Management LLC 0.00% Reduce -3.1% 38,418 $60K
University of Texas/Texas Am Investment Management Co. 0.01% No change 35,714 $56K
New York State Common Retirement Fund 0.00% No change 33,702 $53K
BNP Paribas Financial Markets 0.00% Add +71.2% 31,853 $50K
Tiaa Trust, National Association 0.00% No change 27,057 $42K
Two Sigma Securities, LLC 0.00% Add +38.0% 24,527 $39K
Cerity Partners LLC 0.00% No change 22,512 $35K
Cetera Investment Advisers 0.00% New 21,775 $34K
Principal Securities, Inc. 0.00% No change 20,000 $31K
Vanguard Personalized Indexing Management, LLC 0.00% Add +3.1% 19,922 $31K
Kestra Advisory Services, LLC 0.00% No change 15,500 $24K
Cresset Asset Management, LLC 0.00% No change 15,120 $24K
Prosperity Financial Group, Inc. 0.01% Reduce -54.2% 14,437 $23K
Vermillion & White Wealth Management Group, LLC 0.02% Add +8.1% 13,415 $21K
Truist Financial Corp. 0.00% No change 13,400 $21K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +21.1% 13,074 $21K
North Star Asset Management Inc. 0.00% No change 12,550 $20K
Pinnacle Wealth Management Advisory Group, LLC 0.00% No change 12,445 $20K
State of Wisconsin Investment Board 0.00% New 12,432 $20K
Chemistry Wealth Management LLC 0.00% No change 12,000 $19K
Perennial Investment Advisors, LLC 0.00% New 11,600 $18K
Dynamic Technology Lab Private Ltd 0.00% New 11,338 $18K
Royal Bank of Canada 0.00% Add +5.2% 11,399 $18K
Wolverine Trading, LLC 0.00% New 11,192 $18K
Captrust Financial Advisors 0.00% Add +4.5% 11,350 $18K
Berger Financial Group, Inc 0.00% No change 10,929 $17K
Raymond James & Associates 0.00% No change 10,912 $17K
LifeSteps Financial, Inc. 0.01% No change 10,000 $16K
Legacy Capital Wealth Partners, LLC 0.00% New 10,000 $16K
Estabrook Capital Management 0.00% No change 10,000 $16K
River Wealth Advisors LLC 0.00% No change 10,000 $16K
Ameritas Investment Partners, Inc. 0.00% No change 8,867 $14K
Tower Research Capital LLC (TRC) 0.00% Reduce -64.8% 5,971 $9K
Nordwand Advisors, LLC 0.00% No change 4,000 $6K
Amalgamated Bank 0.00% No change 2,409 $4K
Manchester Capital Management LLC 0.00% No change 2,380 $4K
National Bank of Canada 0.00% Add +0.2% 2,205 $3K
Quintet Private Bank (Europe) S.A. 0.00% Add +14.6% 1,928 $3K
Quadrant Capital Group LLC 0.00% No change 1,371 $2K
Daiwa Securities Group Inc. 0.00% No change 1,369 $2K
Signaturefd, LLC 0.00% No change 1,174 $2K
Global Retirement Partners, LLC 0.00% No change 1,000 $2K
Osaic Holdings, Inc. 0.00% No change 742 $1K
Arax Advisory Partners 0.00% No change 639 $1K
Northwestern Mutual Wealth Management Co. 0.00% No change 500 $785
SJS Investment Consulting Inc. 0.00% No change 400 $628
Steward Partners Investment Advisory, LLC 0.00% New 400 $628
Sterling Capital Management LLC 0.00% — 272 $427
Nisa Investment Advisors, LLC 0.00% Add +21.5% 147 $231
Syntax Research, Inc. 0.00% No change 142 $223
PNC Financial Services Group, Inc. 0.00% No change 111 $174
Larson Financial Group LLC 0.00% No change 100 $157
Coppell Advisory Solutions LLC 0.00% No change 52 $83
Tortoise Investment Management, LLC 0.00% New 21 $33
Earned Wealth Advisors, LLC 0.00% New 18 $28
Federated Hermes, Inc. 0.00% Add +500.0% 6 $9
Farther Finance Advisors, LLC 0.00% No change 2 $3
Cwm, LLC 0.00% Add +49.3% 100 $0
Avion Wealth 0.00% No change 407 $0
Covestor Ltd 0.00% No change 66 $0

"% of holder's portfolio" is LXRX's weight in each manager's 13F, not the share of Lexicon Pharmaceuticals Inc. the manager owns.