Opko HealthOPK
13F holders, Q2 2025 (June 30)222holders −33
13new positions
48sold out
7famous investors
$1.32avg. 13F price*
At the end of Q2 2025, 222 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, down 33 from Q1 2025. 13 opened new positions and 48 sold out. The largest holders were Rubric Capital Management LP ($63.1M), Vanguard Group Inc. ($50.5M) and BlackRock, Inc. ($41.5M). 7 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Mario Gabelli (0.0% of GAMCO Investors's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 13 | $2.7M |
| Exits | 48 | $53.8M |
All 13F filers, Q1 2025 → Q2 2025: 24,449,666 shares bought and 62,786,690 shares sold, net −38,337,024 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 222 holders
| Rubric Capital Management LP | 1.01% | Reduce -1.9% | 47,791,243 | $63.1M |
| Vanguard Group Inc. | 0.00% | Add +29.6% | 38,238,714 | $50.5M |
| BlackRock, Inc. | 0.00% | Add +13.9% | 31,449,482 | $41.5M |
| Geode Capital Management, LLC | 0.00% | Add +23.7% | 10,424,473 | $13.8M |
| State Street Corp. | 0.00% | Add +5.4% | 8,581,840 | $11.3M |
| UBS Group AG | 0.00% | Add +136.6% | 5,719,632 | $7.5M |
| Weiss Asset Management LP | 0.12% | Reduce -57.5% | 4,756,992 | $6.3M |
| Northern Trust Corp. | 0.00% | Reduce -1.3% | 3,482,272 | $4.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +22.2% | 3,350,376 | $4.4M |
| Marshall Wace, LLP | 0.01% | Reduce -31.6% | 3,348,166 | $4.4M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -29.5% | 2,820,055 | $3.7M |
| Morgan Stanley | 0.00% | Reduce -49.9% | 2,059,054 | $2.7M |
| AWM Investment Company, Inc. | 0.30% | Add +8.1% | 2,000,000 | $2.6M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -13.2% | 1,929,683 | $2.5M |
| Graham Capital Management, L.P. | 0.08% | Add +5.6% | 1,911,131 | $2.5M |
| Bank of America Corp. | 0.00% | Reduce -54.1% | 1,906,839 | $2.5M |
| Two Sigma Investments, LP | 0.00% | Add +11.6% | 1,836,747 | $2.4M |
| Whitefort Capital Management, LP | 0.98% | New | 1,774,200 | $2.3M |
| Y.D. More Investments Ltd | 0.14% | Reduce -13.8% | 1,528,899 | $2.0M |
| Jane Street Group, LLC | 0.00% | Add +152.0% | 1,384,552 | $1.8M |
| Invesco Ltd. | 0.00% | Reduce -15.6% | 1,371,045 | $1.8M |
| Washington Growth Strategies LLC | 1.37% | — | 1,356,124 | $1.8M |
| Voya Investment Management LLC | 0.00% | Add +62.9% | 1,319,561 | $1.7M |
| PFG Investments, LLC | 0.10% | Add +3.9% | 1,265,125 | $1.7M |
| Bank of New York Mellon Corp | 0.00% | Add +12.6% | 1,148,906 | $1.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +44.3% | 1,127,476 | $1.5M |
| Nuveen, LLC | 0.00% | Reduce -18.2% | 1,126,557 | $1.5M |
| Tejara Capital Ltd | 0.58% | Add +10.0% | 946,090 | $1.2M |
| AQR Capital Management | 0.00% | Reduce -41.8% | 935,900 | $1.2M |
| Assenagon Asset Management S.A. | 0.00% | No change | 935,100 | $1.2M |
| Clearstead Advisors, LLC | 0.02% | No change | 883,042 | $1.2M |
| Millennium Management | 0.00% | Reduce -89.1% | 695,780 | $918K |
| Barclays PLC | 0.00% | Add +69.5% | 664,407 | $877K |
| Two Sigma Advisers, LP | 0.00% | Add +17.5% | 648,297 | $856K |
| Susquehanna International Group, LLP | 0.00% | Reduce -14.7% | 644,670 | $851K |
| JPMorgan Chase & Co. | 0.00% | Reduce -74.8% | 630,355 | $832K |
| BNP Paribas Financial Markets | 0.00% | Reduce -34.7% | 581,671 | $768K |
| Swiss National Bank | 0.00% | Reduce -12.7% | 577,355 | $762K |
| Commonwealth Equity Services, LLC | 0.00% | Add +15.5% | 554,398 | $732K |
| Rhumbline Advisers | 0.00% | Add +8.0% | 529,553 | $699K |
| Alliancebernstein L.P. | 0.00% | Reduce -7.2% | 468,290 | $618K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -12.8% | 437,506 | $578K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +94.5% | 391,664 | $517K |
| Legal & General Group Plc | 0.00% | Add +1.6% | 355,682 | $469K |
| California State Teachers Retirement System | 0.00% | No change | 324,117 | $428K |
| Wells Fargo & Company | 0.00% | Add +17.9% | 271,094 | $358K |
| Royal Bank of Canada | 0.00% | Add +13.0% | 267,448 | $352K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $323K |
| Deutsche Bank AG | 0.00% | Reduce -15.1% | 239,018 | $316K |
| MetLife Investment Management, LLC | 0.00% | Add +32.9% | 218,272 | $288K |
| Citadel Advisors | 0.00% | Reduce -88.3% | 217,395 | $287K |
| Zazove Associates LLC | 0.56% | No change | 207,600 | $274K |
| SG Americas Securities, LLC | 0.00% | Reduce -41.4% | 206,375 | $272K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $271K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.7% | 198,148 | $262K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $233K |
| GAMCO Investors | 0.00% | No change | 175,000 | $231K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $224K |
| Citigroup Inc. | 0.00% | Reduce -36.7% | 167,111 | $221K |
| Teton Advisors, Inc. | 0.12% | Reduce -1.7% | 142,000 | $187K |
| Intech Investment Management LLC | 0.00% | Reduce -30.7% | 141,624 | $187K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +11.2% | 138,643 | $183K |
| Cubist Systematic Strategies, LLC | 0.00% | Add +12.1% | 133,659 | $176K |
| Csenge Advisory Group | 0.01% | No change | 117,000 | $159K |
| Van Eck Associates Corp. | 0.00% | Add +4.9% | 119,041 | $157K |
| Highline Wealth Partners LLC | 0.05% | No change | 116,680 | $154K |
| Glenmede Investment Management, LP | 0.00% | — | 112,750 | $149K |
| Comerica Bank | 0.00% | No change | 112,000 | $148K |
| Humankind Investments LLC | 0.04% | Add +135.5% | 109,299 | $144K |
| Ieq Capital, LLC | 0.00% | Reduce -40.4% | 109,219 | $144K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.0% | 103,111 | $136K |
| Phoenix Financial Ltd. | 0.00% | No change | 100,000 | $133K |
| Intrepid Capital Management Inc. | 0.07% | No change | 100,000 | $132K |
| Ameriprise Financial Inc. | 0.00% | Add +0.7% | 94,760 | $125K |
| Osaic Holdings, Inc. | 0.00% | Reduce -85.5% | 94,476 | $125K |
| Squarepoint Ops LLC | 0.00% | Reduce -69.4% | 92,434 | $122K |
| Hollencrest Capital Management | 0.01% | No change | 90,000 | $119K |
| 360 Financial, Inc. | 0.04% | Add +12.0% | 88,800 | $117K |
| Arizona State Retirement System | 0.00% | Reduce -9.9% | 88,194 | $116K |
| XTX Topco Ltd | 0.00% | Reduce -72.5% | 84,907 | $112K |
| State of Wyoming | 0.01% | New | 82,007 | $108K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 77,449 | $102K |
| ProShare Advisors LLC | 0.00% | Add +7.4% | 74,184 | $98K |
| KLP Kapitalforvaltning As | 0.00% | No change | 74,000 | $98K |
| SIH Partners, LLLP | 0.01% | New | 69,419 | $92K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $88K |
| Raymond James Financial Inc. | 0.00% | Reduce -22.5% | 66,170 | $87K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $86K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $81K |
| New York State Common Retirement Fund | 0.00% | No change | 60,801 | $80K |
| Cetera Investment Advisers | 0.00% | Add +0.0% | 60,557 | $80K |
| Kestra Private Wealth Services, LLC | 0.00% | No change | 58,450 | $77K |
| Headlands Technologies LLC | 0.01% | Add +10.7% | 57,724 | $76K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 56,800 | $75K |
| Cim Investment Management Inc. | 0.01% | Add +100.7% | 53,591 | $75K |
| Private Advisor Group, LLC | 0.00% | No change | 55,301 | $73K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 55,140 | $73K |
| Engineers Gate Manager LP | 0.00% | Reduce -74.5% | 55,124 | $73K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 54,068 | $71K |
| First Manhattan Co. Llc. | 0.00% | No change | 51,750 | $68K |
| Teacher Retirement System of Texas | 0.00% | Reduce -38.8% | 51,277 | $68K |
| Transcend Capital Advisors, LLC | 0.01% | Add +0.0% | 50,851 | $67K |
| Verition Fund Management LLC | 0.00% | Reduce -84.1% | 50,650 | $67K |
| Farmers National Bank | 0.02% | No change | 50,300 | $66K |
| Prudential Financial Inc. | 0.00% | Add +75.0% | 46,842 | $62K |
| Cibc World Markets Corp. | 0.00% | Reduce -37.0% | 44,575 | $59K |
| Atom Investors LP | 0.01% | Add +6.2% | 43,282 | $57K |
| Captrust Financial Advisors | 0.00% | Reduce -13.5% | 41,927 | $55K |
| Victory Capital Management Inc. | 0.00% | Add +14.1% | 41,761 | $55K |
| World Investment Advisors | 0.00% | No change | 40,618 | $54K |
| RK Asset Management, LLC | 0.05% | No change | 40,485 | $53K |
| Mercer Global Advisors Inc. | 0.00% | Reduce -28.1% | 39,534 | $52K |
| Norges Bank | 0.00% | Reduce -92.0% | 39,477 | $52K |
| Brighton Jones LLC | 0.00% | Add +29.1% | 38,916 | $51K |
| HighTower Advisors, LLC | 0.00% | No change | 38,906 | $51K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -22.9% | 38,807 | $51K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -50.5% | 36,994 | $50K |
| Renaissance Technologies | 0.00% | New | 38,100 | $50K |
| Shell Asset Management Co. | 0.00% | Reduce -9.7% | 37,028 | $49K |
| HSBC Holdings PLC | 0.00% | Reduce -5.2% | 34,939 | $46K |
| Choreo, LLC | 0.00% | No change | 33,757 | $45K |
| Operose Advisors LLC | 0.01% | No change | 32,000 | $42K |
| Norris Perne & French LLP | 0.00% | No change | 32,000 | $42K |
| STRS Ohio | 0.00% | No change | 31,900 | $42K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 31,889 | $42K |
| Kapitalo Investimentos Ltda | 0.01% | New | 31,347 | $41K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -27.6% | 30,713 | $41K |
| Fisher Asset Management | 0.00% | New | 30,301 | $40K |
| IPG Investment Advisors LLC | 0.01% | No change | 30,000 | $40K |
| Diversify Wealth Management, LLC | 0.00% | No change | 30,000 | $40K |
| Orion Porfolio Solutions, LLC | 0.00% | No change | 30,000 | $40K |
| Cibc World Market Inc. | 0.00% | No change | 29,928 | $40K |
| Capital Advisors Inc. | 0.00% | Add +5.7% | 370,000 | $38K |
| Equitable Holdings, Inc. | 0.00% | No change | 28,931 | $38K |
| EP Wealth Advisors, LLC | 0.00% | Reduce -1.2% | 28,900 | $38K |
| Xponance LLC | 0.00% | Add +17.6% | 27,949 | $37K |
| PBMares Wealth Management LLC | 0.01% | No change | 27,021 | $36K |
| Mackenzie Financial Corp. | 0.00% | No change | 25,843 | $34K |
| SlateStone Wealth, LLC | 0.00% | No change | 25,770 | $34K |
| Principal Financial Group Inc. | 0.00% | Add +17.3% | 24,773 | $33K |
| Creative Planning | 0.00% | Reduce -12.8% | 24,492 | $32K |
| Moseley Investment Management Inc. | 0.01% | No change | 24,153 | $32K |
| Mariner, LLC | 0.00% | Add +38.0% | 24,092 | $32K |
| Cwm, LLC | 0.00% | Reduce -69.7% | 22,590 | $30K |
| Altshuler Shaham Ltd | 0.00% | Reduce -98.5% | 22,471 | $30K |
| CIBC Asset Management Inc | 0.00% | No change | 21,918 | $29K |
| Shufro Rose & Co. LLC | 0.00% | No change | 17,000 | $28K |
| X-Square Capital, LLC | 0.01% | Reduce -95.4% | 21,040 | $28K |
| State of Wisconsin Investment Board | 0.00% | Reduce -28.8% | 21,193 | $28K |
| LPL Financial LLC | 0.00% | Reduce -0.5% | 20,236 | $27K |
| Sax Wealth Advisors, LLC | 0.00% | Add +0.3% | 20,160 | $27K |
| Sovereign Financial Group, Inc. | 0.01% | Reduce -0.0% | 20,078 | $27K |
| Cumberland Advisors Inc. | 0.01% | No change | 19,500 | $26K |
| Formidable Asset Management, LLC | 0.00% | No change | 15,046 | $25K |
| Sigma Planning Corp | 0.00% | No change | 17,972 | $24K |
| Stifel Financial Corp. | 0.00% | Reduce -0.9% | 16,689 | $22K |
| Westmount Partners, LLC | 0.01% | No change | 16,550 | $22K |
| Commons Capital, LLC | 0.02% | No change | 16,300 | $22K |
| FMR LLC | 0.00% | Reduce -33.9% | 16,121 | $21K |
| Kovack Advisors, Inc. | 0.00% | Add +50.0% | 15,000 | $20K |
| Colony Family Offices, LLC | 0.01% | No change | 14,729 | $19K |
| Integrated Wealth Concepts LLC | 0.00% | New | 14,322 | $19K |
| Sanctuary Advisors, LLC | 0.00% | Reduce -1.1% | 14,040 | $19K |
| Jones Financial Companies LLLP | 0.00% | Add +14.2% | 13,275 | $18K |
| Mill Creek Capital Advisors, LLC | 0.00% | New | 12,383 | $16K |
| Farther Finance Advisors, LLC | 0.00% | No change | 12,219 | $16K |
| Janney Montgomery Scott LLC | 0.00% | New | 12,500 | $16K |
| Traphagen Investment Advisors LLC | 0.00% | No change | 11,680 | $15K |
| Stillwater Capital Advisors, LLC | 0.00% | No change | 11,380 | $15K |
| Amalgamated Bank | 0.00% | No change | 11,110 | $15K |
| Capital Square, LLC | 0.01% | No change | 11,000 | $15K |
| HBK Sorce Advisory LLC | 0.00% | Reduce -3.1% | 11,057 | $15K |
| Key Financial Inc | 0.00% | No change | 11,000 | $15K |
| Sei Investments Co. | 0.00% | No change | 10,163 | $13K |
| MRP Capital Investments, LLC | 0.01% | No change | 10,000 | $13K |
| Greenbush Financial Group, LLC | 0.01% | No change | 10,000 | $13K |
| KLCM Advisors, Inc. | 0.00% | No change | 10,000 | $13K |
| Simplicity Wealth,LLC | 0.00% | New | 10,000 | $13K |
| Diversified Trust Co. | 0.00% | Reduce -8.4% | 10,000 | $13K |
| Sterling Capital Management LLC | 0.00% | Add +77.5% | 9,768 | $13K |
| Aventura Private Wealth, LLC | 0.00% | No change | 8,400 | $11K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -30.2% | 7,140 | $9K |
| Raiffeisen Bank International AG | 0.00% | No change | 6,521 | $9K |
| National Bank of Canada | 0.00% | Reduce -12.1% | 4,922 | $6K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -3.6% | 4,303 | $6K |
| FSA Wealth Management LLC | 0.00% | No change | 3,950 | $5K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 3,777 | $5K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -82.1% | 3,453 | $5K |
| Larson Financial Group LLC | 0.00% | Add +7500.0% | 3,040 | $4K |
| Gables Capital Management Inc. | 0.00% | No change | 3,000 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +17.4% | 2,677 | $4K |
| Moser Wealth Advisors, LLC | 0.00% | No change | 2,392 | $3K |
| Allworth Financial LP | 0.00% | Add +11.7% | 1,813 | $2K |
| CoreCap Advisors, LLC | 0.00% | Reduce -7.7% | 1,600 | $2K |
| PFS Partners, LLC | 0.00% | No change | 1,100 | $1K |
| Essential Partners LLC | 0.00% | — | 1,024 | $1K |
| MAI Capital Management | 0.00% | No change | 1,000 | $1K |
| Salomon & Ludwin, LLC | 0.00% | Reduce -1.9% | 976 | $1K |
| Transce3nd, LLC | 0.00% | No change | 900 | $1K |
| CBIZ Investment Advisory Services, LLC | 0.00% | No change | 698 | $921 |
| Russell Investments Group, Ltd. | 0.00% | No change | 620 | $818 |
| US Bancorp \de | 0.00% | Reduce -58.0% | 600 | $792 |
| Smartleaf Asset Management LLC | 0.00% | No change | 474 | $625 |
| Physician Wealth Advisors, Inc. | 0.00% | New | 470 | $621 |
| IFP Advisors, Inc | 0.00% | Add +326.2% | 439 | $579 |
| Rothschild Investment LLC | 0.00% | Add +100.0% | 400 | $528 |
| Pittenger & Anderson Inc. | 0.00% | No change | 250 | $330 |
| Northwestern Mutual Wealth Management Co. | 0.00% | No change | 227 | $300 |
| Medallion Wealth Advisors, LLC | 0.00% | No change | 200 | $266 |
| Global Retirement Partners, LLC | 0.00% | — | 200 | $264 |
| Harbor Investment Advisory, LLC | 0.00% | No change | 180 | $238 |
| Salem Investment Counselors Inc. | 0.00% | No change | 100 | $132 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -1.1% | 92 | $121 |
| Boreal Capital Management LLC | 0.00% | — | 69 | $91 |
| True Wealth Design, LLC | 0.00% | Reduce -98.3% | 13 | $18 |
| Darwin Wealth Management, LLC | 0.00% | No change | 5 | $6 |
| Crewe Advisors LLC | 0.00% | New | 1 | $2 |
| NewEdge Advisors, LLC | 0.00% | Reduce -94.7% | 1 | $1 |
| LRI Investments, LLC | 0.00% | No change | 1 | $1 |
| Bessemer Group Inc. | 0.00% | No change | 273 | $0 |
| Centerpoint Advisors, LLC | 0.00% | No change | 100 | $0 |
| Covestor Ltd | 0.00% | Add +110.3% | 183 | $0 |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.