Protagonist TherapeuticsPTGX
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 320 institutions reported holding Protagonist Therapeutics Inc. (PTGX) in their 13F filings, up 4 from Q4 2025. 50 opened new positions and 49 sold out. The largest holders were BlackRock, Inc. ($1.0B), Farallon Capital Management, L.L.C. ($669.2M) and UBS Group AG ($545.7M). 7 famous investors held it, including Stanley Druckenmiller (0.6% of Duquesne Family Office's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Protagonist Therapeutics Inc.
- CUSIP
- 74366E102
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 50 | $221.9M |
| Exits | 49 | $157.7M |
All 13F filers, Q4 2025 → Q1 2026: 10,471,139 shares bought and 4,306,604 shares sold, net +6,164,535 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 320 holders
| BlackRock, Inc. | 0.02% | Add +0.7% | 9,779,369 | $1.0B |
| Farallon Capital Management, L.L.C. | 3.99% | Add +3.3% | 6,348,906 | $669.2M |
| UBS Group AG | 0.10% | Add +86.9% | 5,177,796 | $545.7M |
| RTW Investments, LP | 5.31% | No change | 5,059,053 | $533.2M |
| Wellington Management Group LLP | 0.07% | Add +13.5% | 3,599,644 | $379.4M |
| Vanguard Portfolio Management LLC | 0.02% | — | 3,481,211 | $366.9M |
| State Street Corp. | 0.01% | Reduce -2.6% | 3,116,749 | $328.5M |
| Janus Henderson Group PLC | 0.15% | Add +9.1% | 2,891,527 | $304.9M |
| Vanguard Capital Management LLC | 0.01% | — | 2,805,896 | $295.7M |
| Johnson & Johnson | 39.57% | No change | 2,449,183 | $258.1M |
| Invesco Ltd. | 0.02% | Add +38.1% | 2,164,670 | $228.2M |
| Geode Capital Management, LLC | 0.01% | Add +14.9% | 1,669,371 | $176.0M |
| T. Rowe Price Associates Inc. | 0.02% | Add +18.9% | 1,665,497 | $175.5M |
| Citadel Advisors | 0.12% | Add +37.7% | 1,551,900 | $163.6M |
| Woodline Partners LP | 0.56% | Add +0.4% | 1,414,173 | $149.1M |
| Bank of America Corp. | 0.01% | Add +49.3% | 1,295,434 | $136.5M |
| Perceptive Advisors LLC | 2.57% | Reduce -8.8% | 1,230,879 | $129.7M |
| Jennison Associates LLC | 0.08% | Add +223.7% | 1,072,011 | $113.0M |
| Morgan Stanley | 0.01% | Add +15.8% | 1,018,222 | $107.3M |
| ADAR1 Capital Management, LLC | 6.35% | Reduce -5.3% | 994,119 | $104.8M |
| Hood River Capital Management LLC | 0.88% | New | 829,285 | $87.4M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -19.0% | 778,945 | $82.1M |
| Driehaus Capital Management LLC | 0.56% | Reduce -34.4% | 720,928 | $76.0M |
| FMR LLC | 0.00% | Add +22.6% | 661,997 | $69.8M |
| Marshall Wace, LLP | 0.07% | Reduce -38.7% | 628,075 | $66.2M |
| Clearbridge Investments, LLC | 0.06% | Add +26.9% | 621,820 | $65.5M |
| Alyeska Investment Group, L.P. | 0.18% | Add +197.3% | 593,197 | $62.5M |
| Northern Trust Corp. | 0.01% | Add +2.2% | 587,968 | $62.0M |
| Pictet Asset Management Holding SA | 0.06% | Add +9.7% | 581,083 | $61.2M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 5.11% | No change | 571,825 | $60.3M |
| Charles Schwab Investment Management Inc. | 0.01% | Reduce -0.7% | 552,956 | $58.3M |
| American Century Companies Inc. | 0.03% | Add +0.3% | 537,320 | $56.6M |
| Dimensional Fund Advisors LP | 0.01% | Add +22.6% | 508,103 | $53.5M |
| Voya Investment Management LLC | 0.06% | Add +24.1% | 454,383 | $47.9M |
| Rubric Capital Management LP | 0.55% | New | 427,998 | $45.1M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 412,730 | $43.5M |
| Principal Financial Group Inc. | 0.02% | Add +5.7% | 367,822 | $38.8M |
| 683 Capital Management, LLC | 3.66% | Reduce -6.7% | 355,000 | $37.4M |
| Bank of New York Mellon Corp | 0.01% | Reduce -2.5% | 341,465 | $36.0M |
| Vestal Point Capital, LP | 0.96% | New | 326,159 | $34.4M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Reduce -7.5% | 306,037 | $32.3M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | Add +21.3% | 282,436 | $29.8M |
| SEB Asset Management AB | 0.10% | — | 232,416 | $24.5M |
| NEXTBio Capital Management LP | 11.24% | No change | 229,619 | $24.2M |
| Segall Bryant & Hamill, LLC | 0.32% | Add +64.8% | 212,714 | $22.4M |
| Public Sector Pension Investment Board | 0.07% | Add +3.4% | 210,280 | $22.2M |
| Holocene Advisors, LP | 0.05% | Reduce -0.1% | 209,916 | $22.1M |
| BNP Paribas Financial Markets | 0.01% | Add +99.0% | 194,530 | $20.5M |
| TD Asset Management Inc | 0.02% | Add +15.7% | 183,700 | $19.4M |
| Eagle Health Investments LP | 3.97% | Add +212.9% | 179,322 | $18.9M |
| Fisher Asset Management | 0.01% | Add +167.2% | 173,971 | $18.3M |
| Affinity Asset Advisors, LLC | 1.09% | No change | 172,125 | $18.1M |
| Boxer Capital Management, LLC | 2.35% | No change | 170,000 | $17.9M |
| Raymond James Financial Inc. | 0.01% | Reduce -2.3% | 177,361 | $17.8M |
| Susquehanna International Group, LLP | 0.02% | Add +1324.7% | 167,576 | $17.7M |
| JPMorgan Chase & Co. | 0.00% | Add +11.4% | 172,990 | $17.3M |
| Lord, Abbett & Co. LLC | 0.06% | New | 163,459 | $17.2M |
| Nan Fung Trinity (hk) Ltd. | 1.86% | Reduce -11.1% | 160,670 | $16.9M |
| Duquesne Family Office | 0.57% | No change | 159,700 | $16.8M |
| Citigroup Inc. | 0.01% | Add +67.2% | 158,711 | $16.7M |
| Rhumbline Advisers | 0.01% | Add +1.6% | 157,413 | $16.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -14.1% | 145,690 | $15.4M |
| Neuberger Berman Group LLC | 0.01% | Add +43.6% | 141,441 | $14.9M |
| Franklin Resources Inc. | 0.00% | Add +80.4% | 137,871 | $14.5M |
| Kennedy Capital Management LLC | 0.31% | Reduce -38.1% | 137,099 | $14.5M |
| Legal & General Group Plc | 0.00% | Reduce -9.3% | 135,367 | $14.3M |
| Nuveen, LLC | 0.00% | Add +1.6% | 127,914 | $13.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.8% | 127,818 | $13.5M |
| Deutsche Bank AG | 0.00% | Add +19.0% | 125,451 | $13.2M |
| Panagora Asset Management Inc. | 0.05% | Reduce -7.0% | 116,609 | $12.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.8% | 107,437 | $11.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Reduce -7.5% | 105,514 | $11.1M |
| Balyasny Asset Management L.P. | 0.02% | New | 101,299 | $10.7M |
| Opaleye Management Inc. | 1.39% | Reduce -4.8% | 100,000 | $10.5M |
| Swiss National Bank | 0.01% | Add +0.7% | 98,900 | $10.4M |
| Prudential Financial Inc. | 0.01% | Reduce -13.7% | 95,235 | $10.0M |
| First Trust Advisors LP | 0.01% | Add +89.1% | 87,858 | $9.3M |
| Axiom Investors LLC | 0.10% | Reduce -4.5% | 85,475 | $9.0M |
| Victory Capital Management Inc. | 0.01% | Add +3.7% | 83,544 | $8.8M |
| Sei Investments Co. | 0.01% | Add +122.8% | 83,197 | $8.8M |
| Algert Global LLC | 0.12% | Add +1441.7% | 78,470 | $8.3M |
| Stempoint Capital LP | 1.47% | Add +22.1% | 72,577 | $7.6M |
| Great Lakes Advisors, LLC | 0.06% | Reduce -4.0% | 71,043 | $7.5M |
| Knott David M Jr | 3.95% | Reduce -13.7% | 63,000 | $6.6M |
| Atika Capital Management LLC | 1.03% | Reduce -27.8% | 62,100 | $6.5M |
| Alliancebernstein L.P. | 0.00% | Add +0.8% | 73,790 | $6.4M |
| California State Teachers Retirement System | 0.01% | Add +22.2% | 58,677 | $6.2M |
| Bessemer Group Inc. | 0.01% | Add +0.0% | 54,178 | $5.7M |
| Moody Aldrich Partners LLC | 1.02% | Reduce -33.1% | 53,893 | $5.7M |
| KVP Capital Advisors, LP | 4.17% | No change | 53,000 | $5.6M |
| Nordea Investment Management AB | 0.01% | New | 51,821 | $5.3M |
| EFG International AG | 0.11% | Reduce -31.0% | 50,086 | $5.3M |
| Integral Health Asset Management, LLC | 0.28% | New | 50,000 | $5.3M |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +0.3% | 49,020 | $5.2M |
| Creative Planning | 0.00% | Add +16.3% | 47,971 | $5.1M |
| Silvercrest Asset Management Group LLC | 0.04% | Reduce -9.9% | 47,931 | $5.1M |
| CANADA LIFE ASSURANCE Co | 0.01% | Reduce -4.4% | 47,440 | $5.0M |
| New York State Teachers Retirement System | 0.01% | Reduce -3.9% | 47,424 | $5.0M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -26.6% | 46,752 | $4.9M |
| Assetmark, Inc. | 0.01% | Add +16195.4% | 46,442 | $4.9M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 46,386 | $4.9M |
| Orbimed Advisors LLC | 0.10% | Add +94.0% | 42,100 | $4.4M |
| Russell Investments Group, Ltd. | 0.00% | Add +605.5% | 40,376 | $4.3M |
| Thrivent Financial for Lutherans | 0.01% | Reduce -2.9% | 39,225 | $4.1M |
| Elmind Capital, LP | 1.14% | No change | 38,000 | $4.0M |
| State of Alaska, Department of Revenue | 0.04% | Reduce -2.5% | 37,147 | $3.9M |
| Birchview Capital, LP | 2.10% | Reduce -36.4% | 35,000 | $3.7M |
| HighVista Strategies LLC | 0.99% | Reduce -54.0% | 33,852 | $3.6M |
| MetLife Investment Management, LLC | 0.02% | Reduce -2.0% | 31,799 | $3.4M |
| LMR Partners LLP | 0.04% | Reduce -22.9% | 30,850 | $3.3M |
| State of Wisconsin Investment Board | 0.01% | Reduce -11.6% | 30,767 | $3.2M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -0.6% | 30,604 | $3.2M |
| Wells Fargo & Company | 0.00% | Reduce -58.0% | 30,072 | $3.2M |
| Allspring Global Investments Holdings, LLC | 0.01% | Add +650.7% | 29,916 | $3.1M |
| Illinois Municipal Retirement Fund | 0.04% | Reduce -8.5% | 28,596 | $3.0M |
| Pathstone Holdings, LLC | 0.01% | Add +71.8% | 28,252 | $3.0M |
| Informed Momentum Co LLC | 0.34% | Reduce -64.4% | 27,914 | $2.9M |
| Granahan Investment Management, LLC | 0.14% | New | 27,391 | $2.9M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +105.4% | 27,260 | $2.9M |
| Teachers Retirement System of the State of Kentucky | 0.02% | No change | 26,528 | $2.8M |
| Louisiana State Employees Retirement System | 0.05% | Reduce -3.0% | 26,100 | $2.8M |
| Vanguard Global Advisers, LLC | 0.00% | — | 24,665 | $2.6M |
| Polen Capital Management LLC | 0.02% | Add +19.6% | 24,337 | $2.6M |
| Exchange Traded Concepts, LLC | 0.02% | Reduce -32.1% | 23,773 | $2.5M |
| Calamos Advisors LLC | 0.01% | New | 23,473 | $2.5M |
| State of Tennessee, Department of Treasury | 0.01% | Reduce -1.0% | 23,297 | $2.5M |
| Artia Global Partners LP | 0.54% | Reduce -0.1% | 22,931 | $2.4M |
| Profund Advisors LLC | 0.09% | Reduce -10.6% | 22,867 | $2.4M |
| Natixis Advisors, LLC | 0.00% | Add +10.5% | 22,638 | $2.4M |
| Gotham Asset Management | 0.01% | Reduce -2.0% | 21,155 | $2.2M |
| Handelsbanken Fonder AB | 0.01% | No change | 19,900 | $2.1M |
| New York State Common Retirement Fund | 0.00% | No change | 18,382 | $1.9M |
| SG Americas Securities, LLC | 0.00% | Reduce -9.5% | 18,097 | $1.9M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +0.6% | 17,092 | $1.8M |
| Amalgamated Bank | 0.01% | Reduce -1.2% | 16,852 | $1.8M |
| Envestnet Asset Management Inc. | 0.00% | Add +11.2% | 16,317 | $1.7M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,303 | $1.7M |
| Yousif Capital Management, LLC | 0.02% | Reduce -0.3% | 16,232 | $1.7M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | No change | 15,834 | $1.7M |
| STRS Ohio | 0.01% | Reduce -3.1% | 15,400 | $1.6M |
| Guggenheim Capital LLC | 0.01% | Reduce -50.9% | 15,280 | $1.6M |
| Baron Capital (BAMCO) | 0.00% | Add +80.7% | 15,000 | $1.6M |
| China Universal Asset Management Co., Ltd. | 0.12% | Add +8.2% | 14,923 | $1.6M |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.01% | Reduce -0.1% | 14,532 | $1.5M |
| Bellevue Group AG | 0.04% | Reduce -12.7% | 14,447 | $1.5M |
| Barclays PLC | 0.00% | Reduce -92.3% | 14,405 | $1.5M |
| Royce & Associates LP | 0.01% | Reduce -15.5% | 14,349 | $1.5M |
| Arizona State Retirement System | 0.01% | Reduce -2.0% | 13,738 | $1.4M |
| Oregon Public Employees Retirement Fund | 0.02% | Add +0.5% | 13,456 | $1.4M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +33.1% | 13,412 | $1.4M |
| Fifth Third Bancorp | 0.00% | Add +3937.3% | 13,202 | $1.4M |
| Intech Investment Management LLC | 0.01% | Reduce -42.2% | 13,006 | $1.4M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Reduce -48.8% | 13,000 | $1.4M |
| Bleakley Financial Group, LLC | 0.02% | New | 12,802 | $1.3M |
| Erste Asset Management GmbH | 0.01% | No change | 13,500 | $1.3M |
| WINTON GROUP Ltd | 0.05% | Add +10.5% | 12,673 | $1.3M |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 12,130 | $1.3M |
| ProShare Advisors LLC | 0.00% | Reduce -15.4% | 11,918 | $1.3M |
| AQR Capital Management | 0.00% | Add +70.8% | 11,874 | $1.3M |
| Franklin Street Advisors Inc. | 0.07% | Reduce -1.9% | 11,085 | $1.2M |
| Tidal Investments LLC | 0.00% | New | 11,034 | $1.2M |
| KLP Kapitalforvaltning As | 0.00% | Add +3.8% | 11,000 | $1.2M |
| Hussman Strategic Advisors, Inc. | 0.24% | Reduce -16.7% | 10,500 | $1.1M |
| Nomura Holdings Inc. | 0.01% | Reduce -40.2% | 10,479 | $1.1M |
| Cache Advisors, LLC | 0.12% | No change | 10,143 | $1.1M |
| Weiss Asset Management LP | 0.03% | New | 9,780 | $1.0M |
| J. Goldman & Co LP | 0.05% | Reduce -79.0% | 9,714 | $1.0M |
| Allianz Asset Management GmbH | 0.00% | Reduce -26.1% | 9,600 | $1.0M |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 1.46% | New | 9,334 | $984K |
| Glenmede Trust Co. NA | 0.00% | Reduce -27.6% | 9,235 | $973K |
| AlphaCentric Advisors LLC | 0.95% | Add +5.7% | 9,040 | $953K |
| Maryland State Retirement & Pension System | 0.02% | Reduce -0.4% | 8,567 | $903K |
| Cambria Investment Management, L.P. | 0.04% | Reduce -1.4% | 6,865 | $724K |
| Mutual of America Capital Management LLC | 0.01% | Add +0.1% | 6,725 | $709K |
| Teacher Retirement System of Texas | 0.00% | Reduce -12.3% | 6,448 | $680K |
| Quantinno Capital Management LP | 0.00% | Add +30.1% | 6,437 | $678K |
| Orion Porfolio Solutions, LLC | 0.01% | Add +45.8% | 6,407 | $675K |
| Palumbo Wealth Management LLC | 0.16% | Reduce -4.0% | 6,083 | $641K |
| E Fund Management Co., Ltd. | 0.02% | — | 6,033 | $636K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,001 | $633K |
| Bank of Montreal | 0.00% | Add +51.2% | 5,757 | $607K |
| Cerity Partners LLC | 0.00% | Reduce -37.1% | 5,693 | $600K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +58.8% | 5,672 | $598K |
| Xponance LLC | 0.00% | Add +19.3% | 5,472 | $577K |
| HighTower Advisors, LLC | 0.00% | Reduce -24.4% | 5,386 | $568K |
| Bridgewater Associates | 0.00% | New | 5,276 | $556K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -1.7% | 5,054 | $533K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +142.3% | 4,961 | $523K |
| Brooklyn Investment Group | 0.02% | Add +13.7% | 4,925 | $519K |
| Pacer Advisors, Inc. | 0.00% | New | 4,916 | $518K |
| Rockefeller Capital Management L.P. | 0.00% | Add +46.7% | 4,828 | $509K |
| Los Angeles Capital Management LLC | 0.00% | No change | 4,727 | $498K |
| Ameritas Investment Partners, Inc. | 0.02% | No change | 4,725 | $498K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -1.3% | 4,644 | $489K |
| Cynosure Group, LLC | 0.06% | New | 4,635 | $489K |
| Dymon Asia Capital (singapore) Pte. LTD. | 0.11% | Reduce -54.0% | 4,600 | $485K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 4,486 | $473K |
| Vident Advisory, LLC | 0.00% | Add +6.9% | 4,481 | $472K |
| Keybank National Association | 0.00% | New | 4,286 | $452K |
| Abel Hall, LLC | 0.10% | New | 4,258 | $449K |
| Amundi | 0.00% | New | 4,113 | $434K |
| Abacus Wealth Partners, LLC | 0.04% | Add +8.8% | 4,094 | $432K |
| King Wealth Management Group | 0.05% | No change | 4,000 | $422K |
| Seven Fleet Capital Management LP | 0.13% | Reduce -50.0% | 4,000 | $422K |
| PNC Financial Services Group, Inc. | 0.00% | Add +35.1% | 3,998 | $421K |
| US Bancorp \de | 0.00% | Reduce -10.9% | 3,914 | $413K |
| M&T Bank Corp | 0.00% | Add +2.8% | 3,858 | $407K |
| Nisa Investment Advisors, LLC | 0.00% | Add +0.6% | 3,802 | $401K |
| Vestcor Inc | 0.01% | No change | 3,765 | $397K |
| Hudson Bay Capital Management LP | 0.00% | Reduce -96.6% | 3,760 | $396K |
| Velan Capital Investment Management LP | 0.24% | No change | 3,700 | $390K |
| Jane Street Group, LLC | 0.00% | Reduce -89.5% | 3,607 | $380K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +2.9% | 3,657 | $380K |
| Crossmark Global Holdings, Inc. | 0.01% | Reduce -11.9% | 3,489 | $368K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +9.6% | 3,328 | $351K |
| Gabelli Funds LLC | 0.00% | New | 3,229 | $340K |
| Burney Co./ | 0.01% | Reduce -13.6% | 3,179 | $335K |
| Pinnacle Wealth Planning Services, Inc. | 0.03% | Add +9.4% | 3,132 | $330K |
| Swiss Life Asset Management Ltd | 0.00% | Add +27.7% | 3,104 | $327K |
| PSP Research LLC | 0.22% | Reduce -51.0% | 3,000 | $316K |
| CIBC Bancorp USA Inc. | 0.00% | — | 2,968 | $313K |
| Headlands Technologies LLC | 0.04% | Reduce -82.7% | 2,957 | $312K |
| GAMMA Investing LLC | 0.01% | Add +8.6% | 2,901 | $306K |
| AE Wealth Management LLC | 0.00% | New | 2,888 | $304K |
| Virtus Investment Advisers, LLC | 0.08% | Add +2.5% | 2,860 | $301K |
| Evergreen Capital Management LLC | 0.01% | Add +0.3% | 2,820 | $297K |
| Norden Group LLC | 0.03% | New | 2,810 | $296K |
| LPL Financial LLC | 0.00% | Reduce -14.5% | 2,793 | $294K |
| Mariner, LLC | 0.00% | Reduce -63.6% | 2,775 | $292K |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Add +7.8% | 2,760 | $291K |
| Jones Financial Companies LLLP | 0.00% | Add +6254.4% | 2,923 | $289K |
| New Age Alpha Advisors, LLC | 0.01% | Reduce -2.8% | 2,706 | $285K |
| CIBC Asset Management Inc | 0.00% | No change | 2,667 | $281K |
| Eventide Asset Management, LLC | 0.00% | New | 2,795 | $279K |
| Lanark Financial, Inc. | 0.02% | Reduce -14.4% | 2,547 | $268K |
| Vise Technologies, Inc. | 0.01% | No change | 2,996 | $262K |
| O'shaughnessy Asset Management, LLC | 0.00% | Reduce -44.1% | 2,440 | $257K |
| GTS Securities LLC | 0.01% | New | 2,416 | $255K |
| Empowered Funds, LLC | 0.00% | New | 2,321 | $245K |
| DNB Asset Management AS | 0.00% | New | 2,244 | $237K |
| Choreo, LLC | 0.00% | New | 2,234 | $235K |
| TFB Advisors LLC | 0.12% | New | 2,191 | $231K |
| Concurrent Investment Advisors, LLC | 0.00% | New | 2,060 | $217K |
| Prelude Capital Management, LLC | 0.02% | New | 2,012 | $212K |
| Axiom Investment Management LLC | 0.16% | — | 2,000 | $211K |
| Shelton Capital Management | 0.00% | New | 1,908 | $201K |
| HSBC Holdings PLC | 0.00% | New | 1,907 | $201K |
| Captrust Financial Advisors | 0.00% | Reduce -30.4% | 1,902 | $200K |
| Oppenheimer & Co. Inc. | 0.00% | New | 1,900 | $200K |
| Royal Bank of Canada | 0.00% | Reduce -49.8% | 1,599 | $169K |
| KBC Group NV | 0.00% | No change | 1,574 | $166K |
| Quadrant Capital Group LLC | 0.00% | Reduce -2.6% | 1,429 | $151K |
| GF Fund Management Co. LTD. | 0.00% | Add +14.4% | 1,404 | $148K |
| Osaic Holdings, Inc. | 0.00% | Reduce -71.5% | 1,197 | $126K |
| Truvestments Capital LLC | 0.02% | No change | 1,161 | $122K |
| Federated Hermes, Inc. | 0.00% | New | 1,001 | $106K |
| Canton Hathaway, LLC | 0.02% | No change | 1,000 | $105K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +63.0% | 911 | $96K |
| Covestor Ltd | 0.06% | Reduce -39.1% | 875 | $92K |
| Hantz Financial Services, Inc. | 0.00% | Reduce -9.9% | 857 | $90K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -48.5% | 890 | $89K |
| Larson Financial Group LLC | 0.00% | Add +378.9% | 819 | $86K |
| Cwm, LLC | 0.00% | Add +32.5% | 737 | $78K |
| CFG Wealth Management Services, Inc. | 0.06% | Add +1.5% | 611 | $64K |
| Salomon & Ludwin, LLC | 0.01% | Add +36.5% | 595 | $62K |
| Kemnay Advisory Services Inc. | 0.01% | Add +187.8% | 521 | $55K |
| Sterling Capital Management LLC | 0.00% | Reduce -0.3% | 377 | $40K |
| UMB Bank, n.a. | 0.00% | Add +6.0% | 353 | $37K |
| Toronto Dominion Bank | 0.00% | New | 349 | $37K |
| Ameritas Advisory Services, LLC | 0.00% | New | 334 | $35K |
| Farther Finance Advisors, LLC | 0.00% | Add +12.1% | 333 | $35K |
| Allworth Financial LP | 0.00% | New | 313 | $33K |
| Signaturefd, LLC | 0.00% | Add +76.7% | 288 | $30K |
| Keating Financial Advisory Services, Inc. | 0.00% | Add +11100.0% | 224 | $24K |
| Clearstead Advisors, LLC | 0.00% | Reduce -9.9% | 200 | $21K |
| Twin Peaks Wealth Advisors, LLC | 0.00% | New | 173 | $18K |
| E Fund Management (Hong Kong) Co., Ltd. | 0.01% | New | 156 | $16K |
| Sound Income Strategies, LLC | 0.00% | Reduce -45.1% | 156 | $16K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +5.0% | 125 | $13K |
| Parallel Advisors, LLC | 0.00% | Add +12.8% | 123 | $13K |
| Cedar Mountain Advisors, LLC | 0.00% | New | 113 | $12K |
| Rothschild Investment LLC | 0.00% | Add +24.4% | 107 | $11K |
| WPG Advisers, LLC | 0.01% | Add +1.0% | 97 | $10K |
| Bare Financial Services, Inc | 0.00% | Reduce -13.6% | 95 | $10K |
| Bell Investment Advisors, Inc | 0.00% | No change | 81 | $9K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 81 | $9K |
| Annis Gardner Whiting Capital Advisors, LLC | 0.00% | No change | 76 | $8K |
| Parkside Financial Bank & Trust | 0.00% | Reduce -9.5% | 76 | $8K |
| SBI Securities Co., Ltd. | 0.00% | No change | 70 | $7K |
| Raffa Wealth Management, LLC | 0.00% | No change | 60 | $6K |
| Sankala Group LLC | 0.01% | No change | 60 | $6K |
| Hollencrest Capital Management | 0.00% | New | 45 | $5K |
| MCF Advisors LLC | 0.00% | New | 40 | $4K |
| Wolff Wiese Magana LLC | 0.00% | No change | 35 | $4K |
| Farmers & Merchants Investments Inc. | 0.00% | No change | 35 | $4K |
| Huntington National Bank | 0.00% | No change | 35 | $4K |
| Torren Management, LLC | 0.00% | Reduce -23.1% | 30 | $3K |
| Marquette Asset Management, LLC | 0.00% | No change | 28 | $3K |
| Versant Capital Management, Inc | 0.00% | No change | 27 | $3K |
| Ascentis Independent Advisors | 0.00% | New | 27 | $3K |
| Picton Mahoney Asset Management | 0.00% | No change | 25 | $3K |
| Zions Bancorporation, National Association | 0.00% | New | 23 | $2K |
| Whipplewood Advisors, LLC | 0.00% | New | 22 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 21 | $2K |
| Pension & Wealth Management Advisors, Inc. | 0.00% | New | 20 | $2K |
| Harbour Investments, Inc. | 0.00% | Add +850.0% | 19 | $2K |
| Triumph Capital Management | 0.00% | No change | 18 | $2K |
| Advisory Services Network, LLC | 0.00% | New | 18 | $2K |
| Private Wealth Management Group, LLC | 0.00% | New | 16 | $2K |
| MAI Capital Management | 0.00% | Reduce -85.6% | 14 | $1K |
| Ankerstar Wealth, LLC | 0.00% | No change | 12 | $1K |
| Gilpin Wealth Management, LLC | 0.00% | Add +80.0% | 9 | $949 |
| Rossby Financial, LCC | 0.00% | New | 9 | $933 |
| Trust Co | 0.00% | No change | 7 | $738 |
| Hughes Financial Services, LLC | 0.00% | Add +200.0% | 6 | $632 |
| Kilter Group LLC | 0.00% | No change | 4 | $422 |
| DecisionPoint Financial, LLC | 0.00% | No change | 4 | $422 |
| Prestige Wealth Management Group LLC | 0.00% | New | 3 | $317 |
| Root Financial Partners, LLC | 0.00% | No change | 3 | $316 |
| Abound Wealth Management | 0.00% | Reduce -50.0% | 2 | $211 |
"% of holder's portfolio" is PTGX's weight in each manager's 13F, not the share of Protagonist Therapeutics Inc. the manager owns.