Rhythm PharmaceuticalsRYTM
13F holders, Q1 2025 (March 31)228holders +25
43new positions
19sold out
8famous investors
$53.02avg. 13F price*
At the end of Q1 2025, 228 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 25 from Q4 2024. 43 opened new positions and 19 sold out. The largest holders were BlackRock, Inc. ($363.1M), Ra Capital Management, L.P. ($322.3M) and Primecap Management Co. ($306.6M). 8 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 43 | $128.1M |
| Exits | 19 | $17.7M |
All 13F filers, Q4 2024 → Q1 2025: 7,308,070 shares bought and 7,424,447 shares sold, net −116,377 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 228 holders
| BlackRock, Inc. | 0.01% | Reduce -1.4% | 6,854,755 | $363.1M |
| Ra Capital Management, L.P. | 5.39% | No change | 6,084,412 | $322.3M |
| Primecap Management Co. | 0.25% | Reduce -11.9% | 5,787,322 | $306.6M |
| Baker Bros. Advisors LP | 3.32% | Reduce -7.9% | 5,604,483 | $296.9M |
| Vanguard Group Inc. | 0.00% | Add +0.1% | 3,444,926 | $182.5M |
| NEA Management Company, LLC | 11.87% | No change | 2,909,956 | $154.1M |
| Perceptive Advisors LLC | 4.79% | Reduce -30.8% | 2,548,445 | $135.0M |
| State Street Corp. | 0.00% | Add +7.0% | 1,970,733 | $104.4M |
| Janus Henderson Group PLC | 0.05% | Add +35.7% | 1,655,350 | $90.7M |
| FMR LLC | 0.01% | Add +1392.7% | 1,688,375 | $89.4M |
| Goldman Sachs Group Inc. | 0.02% | Reduce -9.6% | 1,637,908 | $86.8M |
| Federated Hermes, Inc. | 0.18% | Add +2.7% | 1,591,871 | $84.3M |
| Driehaus Capital Management LLC | 0.74% | Add +12.9% | 1,458,022 | $77.2M |
| Westfield Capital Management Co. LP | 0.35% | New | 1,341,092 | $71.0M |
| Geode Capital Management, LLC | 0.01% | Add +2.5% | 1,287,168 | $68.2M |
| T. Rowe Price Associates Inc. | 0.01% | Add +75.0% | 1,199,053 | $63.5M |
| Checkpoint Capital L.P. | 26.37% | Add +24.6% | 907,240 | $48.1M |
| Rock Springs Capital Management LP | 2.54% | Reduce -28.3% | 834,188 | $44.2M |
| Alkeon Capital Management LLC | 0.26% | Reduce -30.0% | 817,700 | $43.3M |
| Frazier Life Sciences Management, L.P. | 1.65% | Reduce -63.7% | 678,760 | $36.0M |
| Hood River Capital Management LLC | 0.60% | Add +2.5% | 659,431 | $34.9M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -2.1% | 605,764 | $32.1M |
| Northern Trust Corp. | 0.00% | Reduce -1.7% | 536,206 | $28.4M |
| Marshall Wace, LLP | 0.04% | Reduce -22.8% | 535,103 | $28.3M |
| Morgan Stanley | 0.00% | Reduce -10.0% | 504,049 | $26.7M |
| Polar Capital Holdings Plc | 0.16% | Reduce -66.7% | 500,000 | $26.5M |
| Opaleye Management Inc. | 5.92% | Reduce -2.0% | 490,000 | $26.0M |
| Sofinnova Investments, Inc. | 1.78% | Add +12.4% | 446,839 | $23.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.2% | 445,429 | $23.6M |
| Voloridge Investment Management, LLC | 0.08% | Add +11.1% | 422,868 | $22.4M |
| Orbimed Advisors LLC | 0.48% | Reduce -5.0% | 380,000 | $20.1M |
| Balyasny Asset Management L.P. | 0.05% | Add +157.1% | 355,712 | $18.8M |
| Silverarc Capital Management, LLC | 3.74% | Add +23.3% | 337,605 | $17.9M |
| Franklin Resources Inc. | 0.01% | Add +21.6% | 326,160 | $17.3M |
| Candriam S.C.A. | 0.10% | Reduce -12.3% | 291,469 | $15.4M |
| Siren, L.L.C. | 0.83% | New | 277,533 | $14.7M |
| UBS Group AG | 0.00% | Add +7.0% | 272,108 | $14.4M |
| Invesco Ltd. | 0.00% | Reduce -13.5% | 261,902 | $13.9M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -30.9% | 259,346 | $13.9M |
| Comerica Bank | 0.05% | Add +1330.2% | 244,754 | $13.0M |
| Norges Bank | 0.00% | Add +8.7% | 223,484 | $11.8M |
| Millennium Management | 0.01% | Add +1324.6% | 217,379 | $11.5M |
| Qube Research & Technologies Ltd | 0.02% | Add +127.0% | 216,193 | $11.5M |
| Cubist Systematic Strategies, LLC | 0.12% | New | 173,822 | $9.2M |
| Cormorant Asset Management, LP | 0.60% | Reduce -62.5% | 150,000 | $7.9M |
| Nuveen, LLC | 0.00% | — | 147,301 | $7.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.1% | 146,585 | $7.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -45.7% | 143,640 | $7.6M |
| Panagora Asset Management Inc. | 0.04% | New | 141,162 | $7.5M |
| Samsara Biocapital, LLC | 1.30% | Reduce -20.0% | 138,118 | $7.3M |
| Lord, Abbett & Co. LLC | 0.03% | Reduce -15.7% | 135,360 | $7.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -42.5% | 125,782 | $6.7M |
| Russell Investments Group, Ltd. | 0.01% | Add +11412.3% | 114,778 | $6.1M |
| Bank of America Corp. | 0.00% | Add +7.0% | 111,752 | $5.9M |
| Aberdeen Group plc | 0.01% | Add +34.3% | 108,129 | $5.7M |
| Lazard Asset Management LLC | 0.01% | Reduce -2.9% | 103,202 | $5.5M |
| PDT Partners, LLC | 0.38% | Add +134.5% | 102,195 | $5.4M |
| Barclays PLC | 0.00% | Reduce -25.2% | 101,217 | $5.4M |
| Ameriprise Financial Inc. | 0.00% | Add +84.2% | 98,281 | $5.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +22.4% | 93,105 | $4.9M |
| Jane Street Group, LLC | 0.01% | Add +56.0% | 91,118 | $4.8M |
| First Trust Advisors LP | 0.00% | Reduce -24.1% | 89,779 | $4.8M |
| Hennion & Walsh Asset Management, Inc. | 0.21% | Reduce -9.9% | 89,622 | $4.7M |
| Swiss National Bank | 0.00% | Reduce -1.0% | 89,300 | $4.7M |
| Citigroup Inc. | 0.00% | Add +23.6% | 86,206 | $4.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1.0% | 86,066 | $4.6M |
| Voya Investment Management LLC | 0.01% | Reduce -11.7% | 85,849 | $4.5M |
| Rhumbline Advisers | 0.00% | Add +3.6% | 85,719 | $4.5M |
| D. E. Shaw & Co. | 0.01% | Add +74.0% | 83,869 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Add +63.8% | 82,980 | $4.4M |
| Harbor Capital Advisors, Inc. | 0.19% | Add +155.5% | 77,297 | $4.1M |
| Wells Fargo & Company | 0.00% | Add +89.3% | 70,638 | $3.7M |
| Citadel Advisors | 0.00% | Add +73.3% | 70,068 | $3.7M |
| Neuberger Berman Group LLC | 0.00% | New | 67,939 | $3.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.4% | 64,386 | $3.4M |
| Point72 Asset Management | 0.01% | New | 63,842 | $3.4M |
| Alliancebernstein L.P. | 0.00% | No change | 61,470 | $3.3M |
| Algert Global LLC | 0.08% | Add +47.9% | 61,461 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Add +14.6% | 57,732 | $3.1M |
| Schonfeld Strategic Advisors LLC | 0.02% | Reduce -4.3% | 57,150 | $3.0M |
| Kennedy Capital Management LLC | 0.07% | New | 54,930 | $2.9M |
| Legal & General Group Plc | 0.00% | Reduce -1.3% | 51,158 | $2.7M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +730.3% | 50,557 | $2.7M |
| TD Asset Management Inc | 0.00% | Add +5.0% | 50,200 | $2.7M |
| Diadema Partners LP | 2.12% | Reduce -33.3% | 50,000 | $2.6M |
| Artia Global Partners LP | 0.78% | No change | 50,000 | $2.6M |
| Nan Fung Group Holdings Ltd | 2.12% | No change | 49,120 | $2.6M |
| Alps Advisors Inc. | 0.01% | Reduce -7.0% | 46,207 | $2.4M |
| Informed Momentum Co LLC | 0.41% | Reduce -28.5% | 45,108 | $2.4M |
| Deutsche Bank AG | 0.00% | Reduce -10.2% | 43,779 | $2.3M |
| California State Teachers Retirement System | 0.00% | Reduce -1.9% | 42,721 | $2.3M |
| Jump Financial, LLC | 0.03% | New | 41,760 | $2.2M |
| Aquatic Capital Management LLC | 0.06% | Add +349.7% | 41,476 | $2.2M |
| AQR Capital Management | 0.00% | Add +148.2% | 39,363 | $2.1M |
| Trexquant Investment LP | 0.02% | Add +396.6% | 38,724 | $2.1M |
| Principal Financial Group Inc. | 0.00% | Add +0.7% | 37,156 | $2.0M |
| Wedge Capital Management L L P | 0.04% | Reduce -23.6% | 36,984 | $2.0M |
| ADAR1 Capital Management, LLC | 0.39% | Add +19.2% | 36,890 | $2.0M |
| Walleye Capital LLC | 0.02% | Reduce -75.2% | 35,828 | $1.9M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +1.1% | 35,392 | $1.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +6.4% | 35,282 | $1.9M |
| HighVista Strategies LLC | 0.72% | Reduce -6.4% | 35,039 | $1.9M |
| Intech Investment Management LLC | 0.02% | Add +20.6% | 33,893 | $1.8M |
| Stempoint Capital LP | 0.57% | Reduce -83.7% | 33,816 | $1.8M |
| State of Wisconsin Investment Board | 0.00% | Add +2.4% | 33,025 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Reduce -3.2% | 32,414 | $1.7M |
| Sei Investments Co. | 0.00% | Reduce -3.4% | 32,381 | $1.7M |
| XTX Topco Ltd | 0.08% | Add +293.8% | 29,949 | $1.6M |
| Tudor Investment Corporation | 0.01% | Add +93.6% | 29,513 | $1.6M |
| Corebridge Financial, Inc. | 0.01% | Reduce -1.5% | 26,821 | $1.4M |
| Dark Forest Capital Management LP | 0.06% | Add +387.6% | 25,409 | $1.3M |
| Squarepoint Ops LLC | 0.00% | New | 24,413 | $1.3M |
| Wellington Management Group LLP | 0.00% | Reduce -7.8% | 23,558 | $1.2M |
| Assenagon Asset Management S.A. | 0.00% | New | 22,192 | $1.2M |
| Engineers Gate Manager LP | 0.02% | Add +14.1% | 21,883 | $1.2M |
| SG Americas Securities, LLC | 0.00% | New | 19,667 | $1.0M |
| Fox Run Management, L.L.C. | 0.16% | New | 19,172 | $1.0M |
| STRS Ohio | 0.00% | Add +12.8% | 18,500 | $980K |
| Stifel Financial Corp. | 0.00% | Reduce -5.3% | 18,487 | $979K |
| Schroder Investment Management Group | 0.00% | New | 17,618 | $965K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 17,659 | $935K |
| Captrust Financial Advisors | 0.00% | New | 17,357 | $919K |
| SummitTX Capital, L.P. | 0.04% | — | 17,343 | $919K |
| Victory Capital Management Inc. | 0.00% | Add +1.0% | 17,326 | $918K |
| Jefferies Financial Group Inc. | 0.02% | New | 17,100 | $906K |
| Quantinno Capital Management LP | 0.01% | Add +6.0% | 17,086 | $905K |
| Handelsbanken Fonder AB | 0.00% | No change | 17,021 | $902K |
| New York State Common Retirement Fund | 0.00% | No change | 16,850 | $893K |
| Leo Wealth, LLC | 0.12% | New | 16,000 | $848K |
| Bellevue Group AG | 0.02% | Reduce -34.1% | 15,550 | $824K |
| HSBC Holdings PLC | 0.00% | Reduce -4.4% | 15,570 | $823K |
| Fiduciary Trust Co | 0.01% | Reduce -25.0% | 15,000 | $795K |
| Atom Investors LP | 0.10% | Add +28.9% | 14,962 | $793K |
| ProShare Advisors LLC | 0.00% | Reduce -19.8% | 14,704 | $779K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 14,670 | $777K |
| Renaissance Technologies | 0.00% | New | 14,112 | $748K |
| Voleon Capital Management LP | 0.06% | New | 13,819 | $732K |
| American Century Companies Inc. | 0.00% | Reduce -60.7% | 13,282 | $704K |
| Arizona State Retirement System | 0.00% | Reduce -0.8% | 13,181 | $698K |
| China Universal Asset Management Co., Ltd. | 0.06% | Reduce -2.7% | 12,682 | $672K |
| Profund Advisors LLC | 0.03% | Add +18.7% | 12,444 | $659K |
| Teacher Retirement System of Texas | 0.00% | Reduce -8.7% | 12,404 | $657K |
| Creative Planning | 0.00% | Add +20.6% | 12,333 | $653K |
| Cibc World Markets Corp. | 0.01% | Add +137.1% | 12,148 | $643K |
| Two Sigma Advisers, LP | 0.00% | Reduce -7.6% | 12,100 | $641K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -3.7% | 11,912 | $631K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | No change | 11,655 | $617K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 11,578 | $615K |
| Persistent Asset Partners Ltd | 0.54% | Reduce -37.2% | 11,501 | $609K |
| Advisors Asset Management, Inc. | 0.01% | Add +44.9% | 10,250 | $543K |
| Cannon Financial Strategists, Inc. | 0.09% | No change | 10,000 | $530K |
| KLP Kapitalforvaltning As | 0.00% | No change | 9,300 | $493K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -1.2% | 8,926 | $473K |
| Aigen Investment Management, LP | 0.07% | New | 7,701 | $408K |
| Point72 (DIFC) Ltd | 0.03% | New | 6,653 | $352K |
| AlphaQuest LLC | 0.04% | Add +660600.0% | 6,607 | $350K |
| Virtus Investment Advisers, LLC | 0.09% | New | 6,446 | $341K |
| Bridgefront Capital, LLC | 0.10% | Add +39.3% | 6,414 | $340K |
| Springhill Fund Asset Management (HK) Co Ltd | 1.59% | New | 6,277 | $332K |
| Allianz Asset Management GmbH | 0.00% | No change | 6,100 | $323K |
| Fieldview Capital Management, LLC | 0.05% | New | 6,037 | $320K |
| BIT Capital GmbH | 0.04% | New | 6,013 | $319K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +1.7% | 5,966 | $316K |
| Jasper Ridge Partners, L.P. | 0.01% | No change | 5,639 | $299K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,546 | $294K |
| Entropy Technologies, LP | 0.03% | New | 5,502 | $291K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,463 | $289K |
| E Fund Management Co., Ltd. | 0.01% | New | 5,396 | $286K |
| Quadrature Capital Ltd | 0.01% | New | 5,278 | $280K |
| Gsa Capital Partners LLP | 0.02% | New | 5,069 | $269K |
| Gotham Asset Management | 0.00% | Reduce -30.0% | 4,750 | $252K |
| Prudential Financial Inc. | 0.00% | Add +4.8% | 4,355 | $243K |
| Avior Wealth Management, LLC | 0.01% | New | 4,589 | $243K |
| Mariner, LLC | 0.00% | Add +1.3% | 4,585 | $243K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1386.2% | 4,518 | $239K |
| Verition Fund Management LLC | 0.00% | Reduce -45.0% | 4,424 | $234K |
| Xponance LLC | 0.00% | Add +4.7% | 4,365 | $231K |
| Cinctive Capital Management LP | 0.02% | Reduce -94.7% | 4,356 | $231K |
| Mackenzie Financial Corp. | 0.00% | No change | 4,343 | $230K |
| Chicago Partners Investment Group LLC | 0.01% | Reduce -5.0% | 3,510 | $227K |
| LPL Financial LLC | 0.00% | Add +0.9% | 4,214 | $223K |
| SIH Partners, LLLP | 0.02% | New | 3,980 | $211K |
| JGP Global Gestao de Recursos Ltda. | 0.15% | Reduce -28.9% | 3,824 | $203K |
| Bayforest Capital Ltd | 0.07% | New | 3,134 | $166K |
| Cwm, LLC | 0.00% | Add +92.3% | 2,584 | $137K |
| KBC Group NV | 0.00% | No change | 2,251 | $119K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +3.3% | 2,116 | $116K |
| Elevation Wealth Partners, LLC | 0.05% | No change | 1,971 | $104K |
| Amalgamated Bank | 0.00% | Add +0.3% | 1,881 | $100K |
| Whittier Trust Co. | 0.00% | No change | 1,760 | $93K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,573 | $83K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -3.5% | 1,240 | $66K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -76.7% | 1,058 | $56K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 648 | $34K |
| Osaic Holdings, Inc. | 0.00% | Reduce -12.3% | 590 | $31K |
| Arax Advisory Partners | 0.00% | Add +14.1% | 518 | $27K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -30.0% | 466 | $25K |
| Ameriflex Group, Inc. | 0.01% | No change | 360 | $19K |
| GAMMA Investing LLC | 0.00% | Add +39.8% | 281 | $15K |
| Smartleaf Asset Management LLC | 0.00% | Add +32.1% | 255 | $14K |
| Jones Financial Companies LLLP | 0.00% | No change | 231 | $13K |
| Signaturefd, LLC | 0.00% | Add +0.9% | 224 | $12K |
| Daiwa Securities Group Inc. | 0.00% | No change | 203 | $11K |
| Optiver Holding B.V. | 0.00% | New | 155 | $8K |
| US Bancorp \de | 0.00% | Add +3.5% | 146 | $8K |
| Truvestments Capital LLC | 0.00% | No change | 138 | $7K |
| Royal Bank of Canada | 0.00% | Reduce -89.2% | 131 | $7K |
| Lindbrook Capital, LLC | 0.00% | Add +2.4% | 129 | $7K |
| Rothschild Investment LLC | 0.00% | Add +38.5% | 90 | $5K |
| Bessemer Group Inc. | 0.00% | Add +120.0% | 66 | $4K |
| SouthState Bank Corp | 0.00% | New | 71 | $4K |
| Allworth Financial LP | 0.00% | New | 50 | $3K |
| Sterling Capital Management LLC | 0.00% | Add +3.6% | 58 | $3K |
| True Wealth Design, LLC | 0.00% | New | 57 | $3K |
| Versant Capital Management, Inc | 0.00% | New | 55 | $3K |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 48 | $3K |
| Coldstream Capital Management Inc. | 0.00% | New | 30 | $2K |
| ORG Partners LLC | 0.00% | New | 24 | $1K |
| Stephens Consulting, LLC | 0.00% | New | 20 | $1K |
| Parkside Financial Bank & Trust | 0.00% | New | 20 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +58.3% | 19 | $1K |
| Parallel Advisors, LLC | 0.00% | No change | 19 | $1K |
| Farther Finance Advisors, LLC | 0.00% | No change | 14 | $700 |
| CVA Family Office, LLC | 0.00% | No change | 12 | $636 |
| Whipplewood Advisors, LLC | 0.00% | Add +18.2% | 13 | $583 |
| Hexagon Capital Partners LLC | 0.00% | Add +57.1% | 11 | $583 |
| Brooklyn Investment Group | 0.00% | New | 5 | $265 |
| Covestor Ltd | 0.00% | Reduce -40.0% | 6 | $0 |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.