Rhythm PharmaceuticalsRYTM
13F holders, Q2 2025 (June 30)227holders −1
31new positions
32sold out
7famous investors
$63.19avg. 13F price*
At the end of Q2 2025, 227 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, down 1 from Q1 2025. 31 opened new positions and 32 sold out. The largest holders were BlackRock, Inc. ($396.0M), Baker Bros. Advisors LP ($354.1M) and Ra Capital Management, L.P. ($351.4M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 31 | $115.8M |
| Exits | 32 | $75.0M |
All 13F filers, Q1 2025 → Q2 2025: 7,625,763 shares bought and 5,899,495 shares sold, net +1,726,268 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 227 holders
| BlackRock, Inc. | 0.01% | Reduce -8.6% | 6,267,538 | $396.0M |
| Baker Bros. Advisors LP | 3.44% | No change | 5,604,483 | $354.1M |
| Ra Capital Management, L.P. | 5.92% | Reduce -8.6% | 5,561,359 | $351.4M |
| Primecap Management Co. | 0.24% | Reduce -15.7% | 4,878,037 | $308.2M |
| Vanguard Group Inc. | 0.00% | Add +4.2% | 3,589,114 | $226.8M |
| NEA Management Company, LLC | 13.84% | No change | 2,909,956 | $183.9M |
| Perceptive Advisors LLC | 5.73% | Reduce -5.1% | 2,418,299 | $152.8M |
| FMR LLC | 0.01% | Add +15.7% | 1,953,441 | $123.4M |
| State Street Corp. | 0.00% | Reduce -3.2% | 1,907,601 | $120.5M |
| Goldman Sachs Group Inc. | 0.02% | Add +5.8% | 1,733,722 | $109.6M |
| Federated Hermes, Inc. | 0.20% | Add +5.9% | 1,686,494 | $106.6M |
| Westfield Capital Management Co. LP | 0.43% | Add +21.5% | 1,629,468 | $103.0M |
| Janus Henderson Group PLC | 0.04% | Reduce -14.7% | 1,411,902 | $89.3M |
| T. Rowe Price Associates Inc. | 0.01% | Add +11.9% | 1,341,392 | $84.8M |
| Geode Capital Management, LLC | 0.01% | Add +1.9% | 1,311,253 | $82.9M |
| Driehaus Capital Management LLC | 0.64% | Reduce -12.9% | 1,269,952 | $80.2M |
| Polar Capital Holdings Plc | 0.42% | Add +150.2% | 1,250,870 | $79.0M |
| Checkpoint Capital L.P. | 31.21% | Add +16.8% | 1,060,000 | $67.0M |
| Alkeon Capital Management LLC | 0.31% | Add +24.5% | 1,017,700 | $64.3M |
| Rock Springs Capital Management LP | 3.40% | Add +3.2% | 861,153 | $54.4M |
| JPMorgan Chase & Co. | 0.00% | Add +445.5% | 783,559 | $49.5M |
| Loomis Sayles & Co. L P | 0.05% | Reduce -2.4% | 591,454 | $37.4M |
| Sofinnova Investments, Inc. | 2.52% | Add +31.1% | 586,010 | $37.0M |
| Franklin Resources Inc. | 0.01% | Add +66.7% | 543,802 | $34.4M |
| Hood River Capital Management LLC | 0.48% | Reduce -17.6% | 543,688 | $34.4M |
| Morgan Stanley | 0.00% | Add +4.0% | 524,480 | $33.1M |
| Woodline Partners LP | 0.17% | New | 514,381 | $32.5M |
| Northern Trust Corp. | 0.00% | Reduce -4.8% | 510,246 | $32.2M |
| Opaleye Management Inc. | 6.21% | Reduce -3.1% | 475,000 | $30.0M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +3.6% | 461,438 | $29.2M |
| Pictet Asset Management Holding SA | 0.03% | Add +60.5% | 416,115 | $26.3M |
| Siren, L.L.C. | 1.34% | Add +47.6% | 409,742 | $25.9M |
| Silverarc Capital Management, LLC | 5.18% | Add +18.7% | 400,772 | $25.3M |
| Marshall Wace, LLP | 0.03% | Reduce -29.7% | 376,242 | $23.8M |
| Barclays PLC | 0.01% | Add +247.0% | 351,198 | $22.2M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | New | 341,000 | $21.5M |
| Voloridge Investment Management, LLC | 0.08% | Reduce -19.9% | 338,804 | $21.4M |
| Renaissance Technologies | 0.03% | Add +2131.4% | 314,893 | $19.9M |
| Candriam S.C.A. | 0.11% | Add +7.2% | 312,452 | $19.7M |
| Clearbridge Investments, LLC | 0.02% | New | 312,445 | $19.7M |
| Comerica Bank | 0.07% | Add +23.3% | 301,661 | $19.1M |
| UBS Group AG | 0.00% | Reduce -7.2% | 252,582 | $16.0M |
| Orbimed Advisors LLC | 0.39% | Reduce -34.6% | 248,512 | $15.7M |
| Voya Investment Management LLC | 0.02% | Add +184.2% | 244,003 | $15.4M |
| Qube Research & Technologies Ltd | 0.02% | Add +11.2% | 240,345 | $15.2M |
| Assenagon Asset Management S.A. | 0.02% | Add +972.5% | 237,998 | $15.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +81.0% | 227,627 | $14.4M |
| Bank of America Corp. | 0.00% | Add +98.8% | 222,152 | $14.0M |
| Norges Bank | 0.00% | Reduce -7.2% | 207,389 | $13.1M |
| Lord, Abbett & Co. LLC | 0.04% | Add +50.9% | 204,275 | $12.9M |
| Millennium Management | 0.01% | Reduce -8.9% | 198,110 | $12.5M |
| Royal Bank of Canada | 0.00% | Add +149698.5% | 196,236 | $12.4M |
| Bank of New York Mellon Corp | 0.00% | Add +25.6% | 184,109 | $11.6M |
| Stempoint Capital LP | 3.60% | Add +422.7% | 176,752 | $11.2M |
| Artisan Partners Limited Partnership | 0.02% | New | 174,479 | $11.0M |
| Ameriprise Financial Inc. | 0.00% | Add +76.1% | 173,069 | $10.9M |
| Point72 Asset Management | 0.03% | Add +167.6% | 170,832 | $10.8M |
| Russell Investments Group, Ltd. | 0.01% | Add +14.1% | 130,998 | $8.3M |
| Logos Global Management LP | 1.10% | New | 130,000 | $8.2M |
| Nuveen, LLC | 0.00% | Reduce -17.3% | 121,855 | $7.7M |
| Integral Health Asset Management, LLC | 0.71% | New | 120,000 | $7.6M |
| Panagora Asset Management Inc. | 0.03% | Reduce -15.4% | 119,466 | $7.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Add +127.7% | 115,118 | $7.3M |
| BNP Paribas Financial Markets | 0.01% | Add +18.8% | 102,239 | $6.5M |
| Lazard Asset Management LLC | 0.01% | Reduce -3.6% | 99,445 | $6.3M |
| PDT Partners, LLC | 0.35% | Reduce -4.5% | 97,638 | $6.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +2.6% | 95,517 | $6.0M |
| Swiss National Bank | 0.00% | Add +1.5% | 90,600 | $5.7M |
| Rhumbline Advisers | 0.00% | Add +2.1% | 87,526 | $5.5M |
| Harbor Capital Advisors, Inc. | 0.23% | Add +12.0% | 86,546 | $5.5M |
| Neuberger Berman Group LLC | 0.00% | Add +26.8% | 86,139 | $5.4M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +36.5% | 77,983 | $4.9M |
| Susquehanna International Group, LLP | 0.01% | Reduce -6.9% | 77,262 | $4.9M |
| First Trust Advisors LP | 0.00% | Reduce -17.9% | 73,714 | $4.7M |
| Cinctive Capital Management LP | 0.25% | Add +1528.5% | 70,937 | $4.5M |
| Invesco Ltd. | 0.00% | Reduce -73.7% | 68,924 | $4.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +5.8% | 68,132 | $4.3M |
| Aberdeen Group plc | 0.01% | Reduce -37.4% | 67,657 | $4.3M |
| Cubist Systematic Strategies, LLC | 0.04% | Reduce -62.9% | 64,577 | $4.1M |
| Alliancebernstein L.P. | 0.00% | No change | 61,470 | $3.9M |
| Algert Global LLC | 0.08% | Reduce -2.0% | 60,219 | $3.8M |
| New York State Common Retirement Fund | 0.00% | Add +247.9% | 58,618 | $3.7M |
| Kennedy Capital Management LLC | 0.09% | Add +4.2% | 57,217 | $3.6M |
| TD Asset Management Inc | 0.00% | Add +11.6% | 56,000 | $3.5M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -84.8% | 54,088 | $3.4M |
| Legal & General Group Plc | 0.00% | Add +3.0% | 52,681 | $3.3M |
| Axiom Investors LLC | 0.03% | New | 52,460 | $3.3M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -10.6% | 51,611 | $3.3M |
| Hennion & Walsh Asset Management, Inc. | 0.13% | Reduce -43.0% | 51,079 | $3.2M |
| Samsara Biocapital, LLC | 0.65% | Reduce -63.5% | 50,476 | $3.2M |
| Nan Fung Group Holdings Ltd | 4.89% | No change | 49,120 | $3.1M |
| AQR Capital Management | 0.00% | Add +24.6% | 49,040 | $3.1M |
| Silvercrest Asset Management Group LLC | 0.02% | New | 48,775 | $3.1M |
| ADAR1 Capital Management, LLC | 0.47% | Add +23.0% | 45,390 | $2.9M |
| California State Teachers Retirement System | 0.00% | Add +0.5% | 42,917 | $2.7M |
| Wells Fargo & Company | 0.00% | Reduce -40.0% | 42,368 | $2.7M |
| Granahan Investment Management, LLC | 0.11% | New | 41,172 | $2.6M |
| Deutsche Bank AG | 0.00% | Reduce -16.0% | 36,779 | $2.3M |
| State of Wisconsin Investment Board | 0.01% | Add +8.1% | 35,708 | $2.3M |
| Dark Forest Capital Management LP | 0.09% | Add +37.1% | 34,829 | $2.2M |
| Citigroup Inc. | 0.00% | Reduce -60.2% | 34,324 | $2.2M |
| Alps Advisors Inc. | 0.01% | Reduce -26.0% | 34,178 | $2.2M |
| Sei Investments Co. | 0.00% | Add +2.4% | 33,145 | $2.1M |
| MetLife Investment Management, LLC | 0.01% | Reduce -0.1% | 32,395 | $2.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -8.3% | 32,351 | $2.0M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -14.2% | 30,373 | $1.9M |
| Wedge Capital Management L L P | 0.03% | Reduce -18.9% | 29,991 | $1.9M |
| HighVista Strategies LLC | 0.65% | Reduce -19.9% | 28,068 | $1.8M |
| Intech Investment Management LLC | 0.02% | Reduce -19.0% | 27,443 | $1.7M |
| SummitTX Capital, L.P. | 0.07% | Add +46.8% | 25,452 | $1.6M |
| Readystate Asset Management LP | 0.12% | New | 24,666 | $1.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -71.0% | 24,278 | $1.5M |
| Wellington Management Group LLP | 0.00% | Reduce -4.8% | 22,425 | $1.4M |
| Bellevue Group AG | 0.03% | Add +34.4% | 20,906 | $1.3M |
| Stifel Financial Corp. | 0.00% | Reduce -1.7% | 18,177 | $1.1M |
| Engineers Gate Manager LP | 0.01% | Reduce -19.2% | 17,676 | $1.1M |
| Jump Financial, LLC | 0.01% | Reduce -57.7% | 17,671 | $1.1M |
| Ensign Peak Advisors, Inc | 0.00% | No change | 17,659 | $1.1M |
| Schroder Investment Management Group | 0.00% | No change | 17,618 | $1.1M |
| Captrust Financial Advisors | 0.00% | Add +0.7% | 17,471 | $1.1M |
| STRS Ohio | 0.00% | Reduce -6.0% | 17,400 | $1.1M |
| Creative Planning | 0.00% | Add +39.6% | 17,222 | $1.1M |
| Victory Capital Management Inc. | 0.00% | Reduce -6.3% | 16,241 | $1.0M |
| Handelsbanken Fonder AB | 0.00% | Reduce -8.8% | 15,521 | $981K |
| Harvest Investment Services, LLC | 0.22% | New | 15,466 | $977K |
| Atom Investors LP | 0.08% | Reduce -0.6% | 14,866 | $939K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 14,670 | $927K |
| Arizona State Retirement System | 0.01% | Add +5.0% | 13,834 | $874K |
| Advisors Asset Management, Inc. | 0.02% | Add +32.6% | 13,596 | $859K |
| ProShare Advisors LLC | 0.00% | Reduce -7.9% | 13,536 | $855K |
| Leo Wealth, LLC | 0.07% | Reduce -16.0% | 13,445 | $850K |
| Point72 (DIFC) Ltd | 0.07% | Add +97.6% | 13,149 | $831K |
| Principal Financial Group Inc. | 0.00% | Reduce -64.8% | 13,067 | $826K |
| China Universal Asset Management Co., Ltd. | 0.08% | Add +0.8% | 12,778 | $807K |
| Teacher Retirement System of Texas | 0.00% | Add +3.0% | 12,772 | $807K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +6.0% | 12,359 | $781K |
| Allianz Asset Management GmbH | 0.00% | Add +98.4% | 12,100 | $765K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 11,578 | $733K |
| Profund Advisors LLC | 0.03% | Reduce -9.6% | 11,254 | $711K |
| Raymond James Financial Inc. | 0.00% | New | 10,546 | $666K |
| KLP Kapitalforvaltning As | 0.00% | Add +9.7% | 10,200 | $645K |
| Cannon Financial Strategists, Inc. | 0.10% | No change | 10,000 | $632K |
| Toth Financial Advisory Corp. | 0.07% | New | 10,000 | $632K |
| Fiduciary Trust Co | 0.01% | Reduce -33.3% | 10,000 | $632K |
| Two Sigma Advisers, LP | 0.00% | Reduce -19.8% | 9,700 | $613K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +8.1% | 9,652 | $610K |
| E. Ohman J:or Asset Management AB | 0.01% | New | 8,213 | $519K |
| Caption Management, LLC | 0.04% | New | 7,540 | $476K |
| Trexquant Investment LP | 0.01% | Reduce -81.7% | 7,083 | $448K |
| Virtus Investment Advisers, LLC | 0.15% | Add +9.4% | 7,052 | $446K |
| Cibc World Markets Corp. | 0.00% | Reduce -44.8% | 6,706 | $424K |
| Prudential Financial Inc. | 0.00% | Add +62.9% | 7,095 | $423K |
| SG Americas Securities, LLC | 0.00% | Reduce -68.5% | 6,185 | $391K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +477.6% | 6,111 | $386K |
| Gsa Capital Partners LLP | 0.03% | Add +20.3% | 6,097 | $385K |
| E Fund Management Co., Ltd. | 0.02% | Add +6.8% | 5,761 | $364K |
| Jasper Ridge Partners, L.P. | 0.01% | No change | 5,639 | $356K |
| Avior Wealth Management, LLC | 0.01% | Add +22.8% | 5,635 | $356K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,546 | $350K |
| PNC Financial Services Group, Inc. | 0.00% | Add +22.7% | 5,543 | $350K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 5,463 | $345K |
| Gotham Asset Management | 0.00% | Add +2.1% | 4,851 | $307K |
| LPL Financial LLC | 0.00% | Add +14.0% | 4,805 | $304K |
| Axq Capital, LP | 0.09% | New | 4,560 | $288K |
| Mackenzie Financial Corp. | 0.00% | Add +1.6% | 4,411 | $279K |
| Chicago Partners Investment Group LLC | 0.01% | Reduce -11.3% | 3,115 | $274K |
| Mariner, LLC | 0.00% | Reduce -5.8% | 4,321 | $273K |
| Xponance LLC | 0.00% | Reduce -2.1% | 4,272 | $270K |
| Tudor Investment Corporation | 0.00% | Reduce -85.5% | 4,272 | $270K |
| Aigen Investment Management, LP | 0.04% | Reduce -45.3% | 4,214 | $266K |
| Aquatic Capital Management LLC | 0.01% | Reduce -90.5% | 3,953 | $250K |
| Jain Global LLC | 0.00% | New | 3,908 | $247K |
| Los Angeles Capital Management LLC | 0.00% | New | 3,872 | $245K |
| JGP Global Gestao de Recursos Ltda. | 0.12% | No change | 3,824 | $242K |
| Freestone Capital Holdings, LLC | 0.01% | New | 3,700 | $234K |
| O'shaughnessy Asset Management, LLC | 0.00% | New | 3,476 | $220K |
| Cwm, LLC | 0.00% | Add +19.6% | 3,091 | $195K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +16.2% | 2,458 | $155K |
| Elevation Wealth Partners, LLC | 0.05% | No change | 1,971 | $125K |
| Amalgamated Bank | 0.00% | No change | 1,881 | $119K |
| Whittier Trust Co. | 0.00% | No change | 1,760 | $111K |
| KBC Group NV | 0.00% | Reduce -24.2% | 1,707 | $108K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,573 | $99K |
| AlphaQuest LLC | 0.01% | Reduce -77.8% | 1,470 | $93K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1.1% | 1,254 | $79K |
| State of Wyoming | 0.01% | New | 1,065 | $67K |
| Osaic Holdings, Inc. | 0.00% | Add +65.9% | 979 | $62K |
| Clearstead Advisors, LLC | 0.00% | New | 590 | $37K |
| Arax Advisory Partners | 0.00% | Add +7.7% | 558 | $35K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 421 | $27K |
| Global Retirement Partners, LLC | 0.00% | — | 400 | $25K |
| Ameriflex Group, Inc. | 0.01% | No change | 360 | $22K |
| Compagnie Lombard Odier SCmA | 0.00% | New | 250 | $16K |
| Jones Financial Companies LLLP | 0.00% | No change | 231 | $14K |
| Signaturefd, LLC | 0.00% | No change | 224 | $14K |
| Daiwa Securities Group Inc. | 0.00% | Add +12.8% | 229 | $14K |
| Optiver Holding B.V. | 0.00% | Add +42.6% | 221 | $14K |
| GAMMA Investing LLC | 0.00% | Reduce -24.9% | 211 | $13K |
| First Horizon Advisors, Inc. | 0.00% | New | 200 | $13K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -64.0% | 168 | $11K |
| True Wealth Design, LLC | 0.00% | Add +157.9% | 147 | $9K |
| US Bancorp \de | 0.00% | No change | 146 | $9K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -43.1% | 145 | $9K |
| Truvestments Capital LLC | 0.00% | No change | 138 | $9K |
| Sterling Capital Management LLC | 0.00% | Add +127.6% | 132 | $8K |
| Essential Partners LLC | 0.00% | — | 120 | $8K |
| Bayforest Capital Ltd | 0.00% | Reduce -96.3% | 116 | $7K |
| Rothschild Investment LLC | 0.00% | Add +16.7% | 105 | $7K |
| SouthState Bank Corp | 0.00% | No change | 71 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +242.1% | 65 | $4K |
| Allworth Financial LP | 0.00% | Add +28.0% | 64 | $4K |
| Bessemer Group Inc. | 0.00% | No change | 66 | $4K |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 58 | $4K |
| WPG Advisers, LLC | 0.00% | New | 57 | $4K |
| Versant Capital Management, Inc | 0.00% | Reduce -34.5% | 36 | $2K |
| Parkside Financial Bank & Trust | 0.00% | Add +65.0% | 33 | $2K |
| Farther Finance Advisors, LLC | 0.00% | Add +107.1% | 29 | $2K |
| ORG Partners LLC | 0.00% | No change | 24 | $2K |
| Brooklyn Investment Group | 0.00% | Add +320.0% | 21 | $1K |
| Parallel Advisors, LLC | 0.00% | No change | 19 | $1K |
| IFP Advisors, Inc | 0.00% | New | 15 | $1K |
| Physician Wealth Advisors, Inc. | 0.00% | New | 16 | $1K |
| CVA Family Office, LLC | 0.00% | No change | 12 | $758 |
| Whipplewood Advisors, LLC | 0.00% | Reduce -15.4% | 11 | $695 |
| Bare Financial Services, Inc | 0.00% | New | 10 | $632 |
| Twin Peaks Wealth Advisors, LLC | 0.00% | New | 5 | $482 |
| Covestor Ltd | 0.00% | Reduce -16.7% | 5 | $0 |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.