Rhythm PharmaceuticalsRYTM

13F holders, Q1 2026 (March 31)
285holders +4
55new positions
51sold out
8famous investors
$87.31avg. 13F price*

At the end of Q1 2026, 285 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 4 from Q4 2025. 55 opened new positions and 51 sold out. The largest holders were Ra Capital Management, L.P. ($579.8M), BlackRock, Inc. ($542.4M) and Baker Bros. Advisors LP ($487.4M). 8 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Rhythm Pharmaceuticals Inc.
CUSIP
76243J105
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 167Q1 2024Q2 2024: 165Q2 2024Q3 2024: 176Q3 2024Q4 2024: 203Q4 2024Q1 2025: 228Q1 2025Q2 2025: 227Q2 2025Q3 2025: 264Q3 2025Q4 2025: 281Q4 2025Q1 2026: 285Q1 2026Q2 2026: 304Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions55$87.7M
Exits51$479.4M

All 13F filers, Q4 2025 → Q1 2026: 8,436,932 shares bought and 7,978,706 shares sold, net +458,226 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 285 holders

Ra Capital Management, L.P. 6.15% No change 6,666,837 $579.8M
BlackRock, Inc. 0.01% Reduce -1.0% 6,237,151 $542.4M
Baker Bros. Advisors LP 2.80% No change 5,604,483 $487.4M
Primecap Management Co. 0.23% Reduce -1.8% 3,417,509 $297.2M
Vanguard Portfolio Management LLC 0.01% — 3,040,718 $264.5M
Vanguard Capital Management LLC 0.01% — 2,967,825 $258.1M
Perceptive Advisors LLC 4.09% Reduce -6.8% 2,373,795 $206.4M
State Street Corp. 0.01% Add +3.3% 2,271,851 $197.6M
Goldman Sachs Group Inc. 0.02% Add +7.3% 1,965,432 $170.9M
Westfield Capital Management Co. LP 0.70% Add +52.2% 1,929,123 $167.8M
FMR LLC 0.01% Reduce -1.0% 1,689,671 $147.0M
T. Rowe Price Associates Inc. 0.02% Add +6.0% 1,654,876 $143.9M
Polar Capital Holdings Plc 0.61% Add +36.3% 1,615,586 $140.5M
Citadel Advisors 0.09% Add +825.3% 1,418,619 $123.4M
Geode Capital Management, LLC 0.01% Add +3.0% 1,416,269 $123.2M
JPMorgan Chase & Co. 0.01% Add +9.1% 1,553,644 $120.0M
Federated Hermes, Inc. 0.18% Reduce -20.8% 1,286,303 $111.9M
Checkpoint Capital L.P. 38.30% Add +23.7% 1,227,200 $106.7M
Alliancebernstein L.P. 0.03% Reduce -2.1% 910,413 $97.5M
Capital Research Global Investors 0.02% Add +13.2% 1,115,460 $97.0M
Janus Henderson Group PLC 0.04% Reduce -18.5% 918,153 $79.9M
Point72 Asset Management 0.13% Add +97.2% 846,801 $73.6M
Woodline Partners LP 0.25% Add +10.2% 758,891 $66.0M
Adage Capital Partners Gp, L.L.C. 0.10% Add +16.8% 725,744 $63.1M
Siren, L.L.C. 1.75% Add +45.1% 725,511 $63.1M
Morgan Stanley 0.00% Add +8.1% 703,978 $61.2M
Rock Springs Capital Management LP 3.54% Reduce -0.8% 689,748 $60.0M
Pictet Asset Management Holding SA 0.06% Add +8.5% 667,046 $57.3M
Bank of America Corp. 0.00% Add +180.1% 628,667 $54.7M
Franklin Resources Inc. 0.01% Reduce -9.9% 626,845 $54.5M
Clearbridge Investments, LLC 0.05% Add +20.4% 609,437 $53.0M
Integral Health Asset Management, LLC 2.76% Add +26.3% 600,000 $52.2M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% Reduce -1.4% 541,450 $47.1M
Charles Schwab Investment Management Inc. 0.01% Reduce -1.1% 526,459 $45.8M
Northern Trust Corp. 0.01% Add +2.1% 498,514 $43.4M
Loomis Sayles & Co. L P 0.05% Reduce -7.7% 465,102 $40.4M
Candriam S.C.A. 0.21% Add +61.3% 464,340 $40.4M
Millennium Management 0.03% Add +142.0% 451,825 $39.3M
Sofinnova Investments, Inc. 1.96% Add +65.8% 450,096 $39.1M
Logos Global Management LP 2.02% Add +136.8% 450,000 $39.1M
Driehaus Capital Management LLC 0.28% Reduce -66.0% 436,546 $38.0M
Vanguard Fiduciary Trust Co. 0.01% — 421,911 $36.7M
Opaleye Management Inc. 4.65% Reduce -62.7% 123,000 $35.3M
Artisan Partners Limited Partnership 0.06% Add +48.2% 390,669 $34.0M
Ameriprise Financial Inc. 0.01% Add +47.0% 383,957 $33.4M
Invesco Ltd. 0.00% Add +25.1% 364,306 $31.7M
Lord, Abbett & Co. LLC 0.10% Reduce -43.7% 348,953 $30.3M
Orbimed Advisors LLC 0.62% Add +31.0% 314,100 $27.3M
Braidwell LP 1.03% New 310,628 $27.0M
Silverarc Capital Management, LLC 3.14% Add +125.1% 306,000 $26.6M
Bank of New York Mellon Corp 0.00% Reduce -2.6% 293,298 $25.5M
Qube Research & Technologies Ltd 0.03% Reduce -10.6% 277,943 $24.2M
Wellington Management Group LLP 0.00% Add +9.4% 273,757 $23.8M
Squarepoint Ops LLC 0.05% Add +701.0% 262,968 $22.9M
Renaissance Technologies 0.04% Reduce -24.4% 258,011 $22.4M
BNP Paribas Financial Markets 0.01% Add +50.6% 247,876 $21.6M
Hood River Capital Management LLC 0.21% Add +1.2% 239,912 $20.9M
Voya Investment Management LLC 0.02% Reduce -6.4% 233,810 $20.3M
UBS Group AG 0.00% Reduce -45.8% 231,650 $20.1M
ADAR1 Capital Management, LLC 1.11% Add +311.8% 211,450 $18.4M
SummitTX Capital, L.P. 0.46% Add +105.1% 165,599 $14.4M
Connor, Clark & Lunn Investment Management Ltd. 0.03% Add +1.6% 151,842 $13.2M
Deutsche Bank AG 0.00% Add +9.7% 141,601 $12.3M
M&G PLC 0.06% Add +1.1% 138,567 $12.1M
PFM Health Sciences, LP 1.27% Add +239.8% 136,621 $11.9M
NEXTBio Capital Management LP 5.09% Add +86.5% 126,078 $11.0M
New York State Common Retirement Fund 0.02% Add +33.7% 125,207 $10.9M
Nuveen, LLC 0.00% Add +1.2% 117,376 $10.2M
Schroder Investment Management Group 0.01% New 131,674 $10.2M
Russell Investments Group, Ltd. 0.01% Reduce -13.8% 115,712 $10.1M
Capital World Investors 0.00% No change 115,693 $10.1M
Swiss National Bank 0.01% Add +0.8% 112,200 $9.8M
Axiom Investors LLC 0.09% Add +9.8% 91,749 $8.0M
First Light Asset Management, LLC 0.68% Reduce -70.5% 87,181 $7.6M
First Trust Advisors LP 0.01% Reduce -3.4% 85,506 $7.4M
Aberdeen Group plc 0.01% New 79,357 $6.9M
Granahan Investment Management, LLC 0.33% Add +45.4% 77,709 $6.8M
Neuberger Berman Group LLC 0.00% Reduce -0.2% 73,434 $6.4M
WCM Investment Management, LLC 0.01% Add +79.9% 80,620 $6.2M
Rhumbline Advisers 0.01% Reduce -1.9% 69,858 $6.1M
Kennedy Capital Management LLC 0.12% Add +65.0% 65,818 $5.7M
California State Teachers Retirement System 0.01% Add +22.9% 65,806 $5.7M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% Reduce -49.0% 62,936 $5.5M
Blue Owl Capital Holdings LP 1.44% New 61,455 $5.3M
XTX Topco Ltd 0.09% Add +470.3% 59,502 $5.2M
AQR Capital Management 0.00% Reduce -15.4% 59,279 $5.2M
Algert Global LLC 0.08% Reduce -33.7% 58,513 $5.1M
Atom Investors LP 0.35% Add +148.6% 57,000 $5.0M
Balyasny Asset Management L.P. 0.01% Reduce -26.7% 52,967 $4.6M
Castleark Management LLC 0.15% Reduce -18.9% 52,279 $4.5M
Susquehanna International Group, LLP 0.01% Add +1139.5% 50,784 $4.4M
Manufacturers Life Insurance Company, The 0.00% Reduce -14.8% 50,769 $4.4M
Picton Mahoney Asset Management 0.05% New 50,372 $4.4M
Rafferty Asset Management, LLC 0.02% Reduce -9.8% 50,105 $4.4M
Raymond James Financial Inc. 0.00% Add +21.4% 49,920 $4.3M
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 49,689 $4.3M
Nan Fung Group Holdings Ltd 3.52% No change 49,120 $4.3M
Harvest Investment Services, LLC 0.77% Add +10.3% 48,468 $4.2M
Legal & General Group Plc 0.00% Reduce -14.6% 47,032 $4.1M
Silvercrest Asset Management Group LLC 0.03% Add +37.4% 46,887 $4.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +1716.7% 43,872 $3.8M
Utah Retirement Systems 0.04% New 42,177 $3.7M
Sei Investments Co. 0.00% Add +8.7% 40,685 $3.5M
Exome Asset Management LLC 2.08% New 40,581 $3.5M
Hillsdale Investment Management Inc. 0.10% Reduce -4.7% 40,300 $3.5M
TD Asset Management Inc 0.00% Reduce -29.6% 38,778 $3.4M
State of Wisconsin Investment Board 0.01% Add +1.4% 36,571 $3.2M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -0.6% 34,677 $3.0M
EFG International AG 0.06% Add +16.8% 34,214 $3.0M
Wells Fargo & Company 0.00% Reduce -53.0% 34,108 $3.0M
Aspiriant, LLC 0.08% New 33,007 $2.9M
Lazard Asset Management LLC 0.00% Add +28.6% 32,888 $2.9M
D. E. Shaw & Co. 0.00% Add +4.1% 32,652 $2.8M
Alyeska Investment Group, L.P. 0.01% New 32,589 $2.8M
Harbor Capital Advisors, Inc. 0.21% Reduce -25.8% 30,353 $2.6M
Prudential Financial Inc. 0.00% Reduce -43.2% 30,190 $2.6M
Vanguard Global Advisers, LLC 0.00% — 29,700 $2.6M
Aquatic Capital Management LLC 0.07% New 29,671 $2.6M
STRS Ohio 0.01% Add +140.9% 28,914 $2.5M
MetLife Investment Management, LLC 0.01% Reduce -1.0% 28,889 $2.5M
PDT Partners, LLC 0.14% Reduce -54.2% 27,232 $2.4M
Wedge Capital Management L L P 0.04% Add +27.5% 24,535 $2.1M
Profund Advisors LLC 0.07% Add +8.3% 22,787 $2.0M
Mutual of America Capital Management LLC 0.02% New 22,529 $2.0M
Creative Planning 0.00% Reduce -16.4% 21,085 $1.8M
Liberty Mutual Group Asset Management Inc. 0.14% New 20,514 $1.8M
Victory Capital Management Inc. 0.00% Reduce -54.8% 20,504 $1.8M
Tudor Investment Corporation 0.01% New 19,646 $1.7M
State of New Jersey Common Pension Fund D 0.01% Add +0.6% 19,386 $1.7M
Dimensional Fund Advisors LP 0.00% Reduce -40.2% 19,151 $1.7M
SG Americas Securities, LLC 0.00% Add +59.8% 18,760 $1.6M
Advisors Asset Management, Inc. 0.03% Add +1.1% 18,718 $1.6M
Captrust Financial Advisors 0.00% Reduce -1.0% 18,147 $1.6M
ExodusPoint Capital Management, LP 0.02% Reduce -76.3% 17,775 $1.5M
Handelsbanken Fonder AB 0.01% No change 17,521 $1.5M
HighVista Strategies LLC 0.40% Reduce -60.8% 16,796 $1.5M
Guggenheim Capital LLC 0.01% Add +33.5% 16,554 $1.4M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +25.4% 15,598 $1.4M
Knights of Columbus Asset Advisors LLC 0.08% Add +51.1% 15,589 $1.4M
Arizona State Retirement System 0.01% Reduce -1.1% 15,581 $1.4M
State Board of Administration of Florida Retirement System 0.00% No change 14,650 $1.3M
Police & Firemen's Retirement System of New Jersey 0.01% Add +2.9% 14,594 $1.3M
HSBC Holdings PLC 0.00% New 14,307 $1.2M
Vanguard Investments Australia, Ltd. 0.00% — 13,927 $1.2M
Jasper Ridge Partners, L.P. 0.03% Add +145.5% 13,845 $1.2M
Intech Investment Management LLC 0.01% Reduce -35.6% 13,739 $1.2M
KLP Kapitalforvaltning As 0.00% Add +4.2% 12,500 $1.1M
Bridgefront Capital, LLC 0.27% New 12,495 $1.1M
Stifel Financial Corp. 0.00% Reduce -6.8% 12,339 $1.1M
Citigroup Inc. 0.00% Reduce -3.0% 12,336 $1.1M
China Universal Asset Management Co., Ltd. 0.08% Add +11.4% 12,118 $1.1M
DNB Asset Management AS 0.00% Add +0.3% 11,195 $974K
ProShare Advisors LLC 0.00% Reduce -15.1% 10,720 $932K
Barclays PLC 0.00% Reduce -91.9% 10,652 $926K
Entropy Technologies, LP 0.04% Add +314.0% 10,318 $897K
Cannon Financial Strategists, Inc. 0.11% No change 10,000 $870K
Toth Financial Advisory Corp. 0.10% No change 10,000 $870K
Marshall Wace, LLP 0.00% New 9,628 $837K
AlphaCentric Advisors LLC 0.81% Add +84.0% 9,297 $809K
Los Angeles Capital Management LLC 0.00% Reduce -62.1% 9,219 $802K
Hudson Bay Capital Management LP 0.01% New 9,120 $793K
HighTower Advisors, LLC 0.00% New 9,058 $788K
CenterBook Partners LP 0.04% New 9,026 $785K
Exchange Traded Concepts, LLC 0.01% Add +39.2% 8,463 $736K
Prelude Capital Management, LLC 0.06% New 8,372 $728K
Tower Research Capital LLC (TRC) 0.02% Add +160.5% 7,715 $671K
Virtus Investment Advisers, LLC 0.18% Add +23.6% 7,434 $647K
Teacher Retirement System of Texas 0.00% Reduce -12.3% 7,330 $637K
PNC Financial Services Group, Inc. 0.00% Add +48.9% 6,938 $603K
IMC-Chicago, LLC 0.01% New 6,697 $582K
E Fund Management Co., Ltd. 0.02% — 6,453 $561K
LPL Financial LLC 0.00% Add +14.2% 6,198 $539K
Texas Treasury Safekeeping Trust Co. 0.09% New 6,154 $535K
Campbell & CO Investment Adviser LLC 0.03% New 5,958 $518K
CANADA LIFE ASSURANCE Co 0.00% No change 5,797 $507K
Blueshift Asset Management, LLC 0.15% Add +100.9% 5,787 $503K
Principal Financial Group Inc. 0.00% Reduce -9.1% 5,637 $490K
Public Employees Retirement Association of Colorado 0.00% No change 5,463 $475K
Fifth Third Bancorp 0.00% New 5,260 $457K
Xponance LLC 0.00% Add +16.9% 4,990 $434K
Gotham Asset Management 0.00% Reduce -0.1% 4,848 $422K
Rockefeller Capital Management L.P. 0.00% Reduce -58.9% 4,844 $421K
Avior Wealth Management, LLC 0.01% Add +30.2% 4,650 $404K
E. Ohman J:or Asset Management AB 0.01% Reduce -33.1% 4,409 $383K
Inceptionr LLC 0.09% New 4,379 $381K
Ameritas Investment Partners, Inc. 0.01% No change 4,365 $380K
Two Sigma Investments, LP 0.00% New 4,300 $374K
Jones Financial Companies LLLP 0.00% Add +2029.0% 4,918 $373K
Man Group plc 0.00% Reduce -57.9% 4,022 $350K
Amundi 0.00% New 4,017 $349K
Abel Hall, LLC 0.07% Add +87.6% 4,015 $349K
Centiva Capital, LP 0.02% New 4,000 $348K
Fox Run Management, L.L.C. 0.06% New 4,499 $348K
Ensign Peak Advisors, Inc 0.00% No change 3,859 $336K
Quantinno Capital Management LP 0.00% Add +0.5% 3,851 $335K
Bank of Montreal 0.00% New 3,801 $331K
Brevan Howard Capital Management LP 0.00% New 3,777 $328K
Freestone Capital Holdings, LLC 0.01% No change 3,700 $322K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +9.8% 3,562 $310K
Swiss Life Asset Management Ltd 0.00% Add +25.9% 3,341 $291K
Marex Group Ltd 0.00% New 3,288 $286K
Cerity Partners LLC 0.00% Reduce -12.3% 3,215 $280K
Vanguard Personalized Indexing Management, LLC 0.00% Add +30.4% 3,102 $270K
Leo Wealth, LLC 0.02% Reduce -55.6% 3,088 $269K
Chicago Partners Investment Group LLC 0.01% Add +14.1% 3,125 $266K
Ethic Inc. 0.00% New 3,003 $261K
Allianz Asset Management GmbH 0.00% Reduce -62.5% 3,000 $261K
Cim Investment Management Inc. 0.07% No change 2,993 $260K
CIBC Asset Management Inc 0.00% No change 2,848 $248K
MAI Capital Management 0.00% Add +135400.0% 2,710 $236K
CIBC Bancorp USA Inc. 0.00% — 2,663 $232K
Blackstone Inc. 0.00% New 2,600 $226K
DRW Securities, LLC 0.01% New 2,562 $223K
Two Sigma Securities, LLC 0.03% Reduce -48.5% 2,545 $221K
Cwm, LLC 0.00% Reduce -8.3% 2,536 $221K
Northwest & Ethical Investments L.P. 0.01% New 2,491 $217K
Integrated Wealth Concepts LLC 0.00% New 2,480 $216K
Cornerstone Partners Capital Management, LLC 0.53% New 2,462 $214K
Verdad Advisers, LP 0.24% New 2,445 $213K
Centaurus Financial, Inc. 0.01% Reduce -3.1% 2,314 $201K
Acadian Asset Management LLC 0.00% Reduce -63.7% 2,218 $192K
Elevation Wealth Partners, LLC 0.06% No change 1,971 $171K
Whittier Trust Co. 0.00% No change 1,811 $157K
KBC Group NV 0.00% No change 1,707 $148K
GF Fund Management Co. LTD. 0.00% Add +14.3% 1,498 $130K
Quantbot Technologies LP 0.00% New 1,363 $119K
Nisa Investment Advisors, LLC 0.00% Reduce -91.3% 1,138 $99K
US Bancorp \de 0.00% Add +9.2% 1,041 $91K
Bellevue Group AG 0.00% Reduce -86.5% 1,016 $88K
Mitsubishi UFJ Asset Management (UK) Ltd. 0.04% New 1,000 $87K
Osaic Holdings, Inc. 0.00% Reduce -9.6% 939 $82K
Farther Finance Advisors, LLC 0.00% Add +0.5% 645 $57K
Kemnay Advisory Services Inc. 0.01% Add +171.5% 562 $49K
EverSource Wealth Advisors, LLC 0.00% Add +106.4% 549 $48K
Arax Advisory Partners 0.00% Reduce -3.4% 368 $32K
Sterling Capital Management LLC 0.00% Reduce -0.3% 343 $30K
SBI Securities Co., Ltd. 0.00% Reduce -11.9% 302 $26K
GAMMA Investing LLC 0.00% Reduce -26.0% 267 $23K
Covestor Ltd 0.01% Reduce -57.7% 245 $21K
Smartleaf Asset Management LLC 0.00% Reduce -33.8% 264 $20K
Signaturefd, LLC 0.00% Reduce -3.5% 224 $19K
E Fund Management (Hong Kong) Co., Ltd. 0.01% New 154 $13K
True Wealth Design, LLC 0.00% No change 147 $13K
Truvestments Capital LLC 0.00% No change 138 $12K
Essential Partners LLC 0.00% Reduce -46.2% 120 $10K
Sound Income Strategies, LLC 0.00% New 114 $10K
Basecamp Wealth Advisors LLC 0.00% Reduce -8.8% 114 $10K
Danske Bank A/S 0.00% Reduce -90.9% 100 $9K
Cassaday & Co Wealth Management LLC 0.00% New 93 $8K
Rothschild Investment LLC 0.00% Reduce -5.5% 86 $7K
Allworth Financial LP 0.00% Reduce -23.9% 83 $7K
WPG Advisers, LLC 0.00% No change 60 $5K
Harbour Investments, Inc. 0.00% No change 60 $5K
Eastern Bank 0.00% No change 59 $5K
Royal Bank of Canada 0.00% Reduce -96.3% 62 $5K
Larson Financial Group LLC 0.00% Reduce -32.5% 52 $5K
Cedar Mountain Advisors, LLC 0.00% New 51 $4K
Optiver Holding B.V. 0.00% Reduce -45.6% 50 $4K
IFP Advisors, Inc 0.00% Add +27.8% 46 $4K
Advisory Services Network, LLC 0.00% New 37 $3K
Ascentis Independent Advisors 0.00% New 37 $3K
Versant Capital Management, Inc 0.00% No change 36 $3K
First Horizon Corp. 0.00% Add +16.7% 35 $3K
Bessemer Group Inc. 0.00% Reduce -54.5% 30 $3K
Parkside Financial Bank & Trust 0.00% No change 33 $3K
Root Financial Partners, LLC 0.00% Reduce -27.9% 31 $3K
CVA Family Office, LLC 0.00% Add +133.3% 28 $2K
Parallel Advisors, LLC 0.00% No change 25 $2K
Physician Wealth Advisors, Inc. 0.00% No change 16 $1K
Bare Financial Services, Inc 0.00% Reduce -40.9% 13 $1K
Whipplewood Advisors, LLC 0.00% New 11 $957
Dogwood Wealth Management LLC 0.00% New 11 $957
Keating Financial Advisory Services, Inc. 0.00% Add +22.2% 11 $957
JFS Wealth Advisors, LLC 0.00% No change 10 $870
Fortitude Family Office, LLC 0.00% Add +50.0% 9 $783
Twin Peaks Wealth Advisors, LLC 0.00% New 6 $522
Toronto Dominion Bank 0.00% No change 6 $522
LRI Investments, LLC 0.00% New 6 $522
Huntington National Bank 0.00% New 5 $435
Godfrey Financial Associates, Inc. 0.00% New 3 $261
GHP Investment Advisors, Inc. 0.00% New 3 $261
DiNuzzo Private Wealth, Inc. 0.00% No change 3 $261
Pinnacle Wealth Planning Services, Inc. 0.00% New 2 $174
HFM Investment Advisors, LLC 0.00% Reduce -50.0% 1 $87
Bay Harbor Wealth Management, LLC 0.00% No change 1 $86

"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.