Xenon PharmaceuticalsXENE
13F holders, Q4 2024 (December 31)209holders +6
23new positions
19sold out
6famous investors
$39.20avg. 13F price*
At the end of Q4 2024, 209 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, up 6 from Q3 2024. 23 opened new positions and 19 sold out. The largest holders were FMR LLC ($295.0M), Avoro Capital Advisors LLC ($222.1M) and Driehaus Capital Management LLC ($177.2M). 6 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Ron Baron (0.0% of Baron Capital (BAMCO)'s portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $62.0M |
| Exits | 19 | $23.6M |
All 13F filers, Q3 2024 → Q4 2024: 5,652,780 shares bought and 4,282,362 shares sold, net +1,370,418 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 209 holders
| FMR LLC | 0.02% | Add +8.8% | 7,525,290 | $295.0M |
| Avoro Capital Advisors LLC | 3.14% | No change | 5,666,666 | $222.1M |
| Driehaus Capital Management LLC | 1.46% | Reduce -1.6% | 4,520,595 | $177.2M |
| Wellington Management Group LLP | 0.03% | Reduce -1.7% | 3,777,611 | $148.1M |
| Braidwell LP | 5.10% | Add +7.6% | 2,913,964 | $114.2M |
| Janus Henderson Group PLC | 0.06% | Add +12.3% | 2,866,755 | $112.4M |
| Commodore Capital LP | 7.87% | Add +1.5% | 2,740,000 | $107.4M |
| Polar Capital Holdings Plc | 0.60% | Add +10.3% | 2,697,657 | $105.7M |
| Capital International Investors | 0.02% | Reduce -1.3% | 2,547,210 | $99.9M |
| Capital World Investors | 0.01% | Reduce -14.4% | 2,294,537 | $89.9M |
| BlackRock, Inc. | 0.00% | Reduce -0.0% | 2,105,236 | $82.5M |
| Adage Capital Partners Gp, L.L.C. | 0.13% | Reduce -10.6% | 1,863,473 | $73.0M |
| Pictet Asset Management Holding SA | 0.06% | Reduce -2.1% | 1,496,511 | $58.7M |
| Alliancebernstein L.P. | 0.02% | Add +1.3% | 1,443,180 | $56.6M |
| T. Rowe Price Investment Management, Inc. | 0.03% | Reduce -4.4% | 1,437,831 | $56.4M |
| JPMorgan Chase & Co. | 0.00% | Add +38.9% | 1,356,895 | $53.2M |
| Rock Springs Capital Management LP | 1.87% | Reduce -4.9% | 1,251,859 | $49.1M |
| Affinity Asset Advisors, LLC | 7.74% | Add +1.5% | 1,161,237 | $45.5M |
| First Light Asset Management, LLC | 4.35% | Reduce -1.8% | 1,160,580 | $45.5M |
| Westfield Capital Management Co. LP | 0.20% | Add +72.8% | 1,157,189 | $45.4M |
| Samlyn Capital, LLC | 0.64% | Reduce -0.2% | 1,017,838 | $39.9M |
| Baker Bros. Advisors LP | 0.42% | No change | 993,679 | $39.0M |
| Orbimed Advisors LLC | 0.77% | Add +4.0% | 947,877 | $37.2M |
| Marshall Wace, LLP | 0.04% | Reduce -24.7% | 899,718 | $35.3M |
| TimesSquare Capital Management, LLC | 0.48% | Add +9.1% | 848,850 | $33.3M |
| Vestal Point Capital, LP | 1.88% | Reduce -1.8% | 810,000 | $31.8M |
| Jennison Associates LLC | 0.02% | Add +39.0% | 801,553 | $31.4M |
| Siren, L.L.C. | 1.29% | No change | 743,769 | $29.2M |
| Loomis Sayles & Co. L P | 0.03% | Reduce -2.8% | 687,145 | $26.9M |
| First Turn Management, LLC | 4.81% | Add +110.6% | 684,986 | $26.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +51.2% | 663,704 | $26.0M |
| Boxer Capital Management, LLC | 2.00% | — | 600,000 | $23.5M |
| Franklin Resources Inc. | 0.01% | Add +1.7% | 575,590 | $22.6M |
| Federated Hermes, Inc. | 0.05% | Reduce -24.1% | 558,500 | $21.9M |
| Fiera Capital Corp | 0.07% | Reduce -3.3% | 535,887 | $21.0M |
| Candriam S.C.A. | 0.11% | Add +6.1% | 492,181 | $19.3M |
| Avidity Partners Management LP | 1.85% | Reduce -42.0% | 474,000 | $18.6M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -10.7% | 410,246 | $16.1M |
| Stempoint Capital LP | 3.70% | New | 375,845 | $14.7M |
| Millennium Management | 0.01% | Add +65.5% | 346,040 | $13.6M |
| Vanguard Group Inc. | 0.00% | Reduce -0.5% | 342,779 | $13.4M |
| Citadel Advisors | 0.01% | Reduce -54.7% | 327,303 | $12.8M |
| Perceptive Advisors LLC | 0.36% | Reduce -38.0% | 325,324 | $12.8M |
| Saturn V Capital Management LP | 4.95% | New | 322,470 | $12.6M |
| Two Sigma Advisers, LP | 0.03% | Add +9.1% | 298,700 | $11.7M |
| Alyeska Investment Group, L.P. | 0.04% | No change | 288,843 | $11.3M |
| State Street Corp. | 0.00% | Add +3.3% | 288,722 | $11.3M |
| Altium Capital Management LLC | 3.52% | Reduce -20.1% | 288,000 | $11.3M |
| Aberdeen Group plc | 0.02% | Add +14.3% | 283,899 | $11.1M |
| DAFNA Capital Management LLC | 2.76% | No change | 273,739 | $10.7M |
| Two Sigma Investments, LP | 0.03% | Add +12.2% | 273,352 | $10.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -13.3% | 259,970 | $10.2M |
| Great Point Partners LLC | 4.53% | New | 245,272 | $9.6M |
| Algert Global LLC | 0.22% | Add +9.9% | 241,417 | $9.5M |
| Assenagon Asset Management S.A. | 0.02% | Add +12.4% | 238,522 | $9.4M |
| Walleye Capital LLC | 0.09% | Add +111.5% | 221,982 | $8.7M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -4.4% | 213,696 | $8.4M |
| Invesco Ltd. | 0.00% | Reduce -2.9% | 209,554 | $8.2M |
| DNB Asset Management AS | 0.03% | Add +6.6% | 203,243 | $8.0M |
| MPM Bioimpact LLC | 1.10% | Add +18.9% | 197,212 | $7.7M |
| Lord, Abbett & Co. LLC | 0.03% | Add +12.1% | 194,971 | $7.6M |
| Parkman Healthcare Partners LLC | 1.01% | Add +0.7% | 193,004 | $7.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +17.9% | 191,852 | $7.5M |
| AXA S.A. | 0.02% | Reduce -0.2% | 187,796 | $7.4M |
| Balyasny Asset Management L.P. | 0.02% | Add +119.2% | 184,580 | $7.2M |
| Granahan Investment Management, LLC | 0.30% | Reduce -9.2% | 182,333 | $7.1M |
| Schroder Investment Management Group | 0.01% | No change | 176,674 | $6.8M |
| Deep Track Capital, LP | 0.25% | New | 169,132 | $6.6M |
| Eversept Partners, LP | 0.63% | New | 155,540 | $6.1M |
| Bridger Management, LLC | 3.09% | No change | 146,800 | $5.8M |
| New York State Common Retirement Fund | 0.01% | No change | 132,521 | $5.2M |
| Ally Bridge Group (NY) LLC | 4.35% | Reduce -39.0% | 129,291 | $5.1M |
| Swiss National Bank | 0.00% | Add +1.0% | 126,600 | $5.0M |
| PFM Health Sciences, LP | 0.36% | Reduce -35.0% | 116,998 | $4.6M |
| Bank of America Corp. | 0.00% | Reduce -16.1% | 106,906 | $4.2M |
| Nan Fung Group Holdings Ltd | 3.58% | No change | 106,680 | $4.2M |
| Baron Capital (BAMCO) | 0.01% | No change | 100,100 | $3.9M |
| State of Wisconsin Investment Board | 0.01% | Reduce -4.4% | 96,584 | $3.8M |
| Neuberger Berman Group LLC | 0.00% | New | 92,961 | $3.6M |
| Ameriprise Financial Inc. | 0.00% | Add +39.1% | 92,350 | $3.6M |
| D. E. Shaw & Co. | 0.00% | Reduce -57.5% | 86,973 | $3.4M |
| Atika Capital Management LLC | 0.37% | Reduce -42.4% | 72,600 | $2.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.1% | 69,529 | $2.7M |
| ExodusPoint Capital Management, LP | 0.03% | Reduce -73.8% | 68,884 | $2.7M |
| Morgan Stanley | 0.00% | Reduce -71.6% | 68,062 | $2.7M |
| HighVista Strategies LLC | 0.97% | Reduce -9.4% | 66,788 | $2.6M |
| Northern Trust Corp. | 0.00% | Add +51.5% | 65,783 | $2.6M |
| Voya Investment Management LLC | 0.00% | Add +32.3% | 62,415 | $2.4M |
| Ikarian Capital, LLC | 0.69% | Reduce -42.1% | 62,052 | $2.4M |
| Alps Advisors Inc. | 0.02% | Add +8.2% | 61,648 | $2.4M |
| Legal & General Group Plc | 0.00% | Add +9.6% | 60,406 | $2.4M |
| Royal Bank of Canada | 0.00% | Add +59.6% | 60,068 | $2.4M |
| Wells Fargo & Company | 0.00% | Reduce -1.6% | 59,520 | $2.3M |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 55,492 | $2.2M |
| Moore Capital Management, LP | 0.04% | No change | 55,000 | $2.2M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +11.2% | 54,033 | $2.1M |
| BIT Capital GmbH | 0.19% | New | 53,928 | $2.1M |
| Deutsche Bank AG | 0.00% | No change | 53,711 | $2.1M |
| Sphera Funds Management LTD. | 0.38% | New | 52,097 | $2.0M |
| ADAR1 Capital Management, LLC | 0.42% | Add +81.2% | 50,547 | $2.0M |
| Harbor Capital Advisors, Inc. | 0.09% | Add +3.6% | 49,818 | $2.0M |
| Erste Asset Management GmbH | 0.02% | No change | 50,000 | $1.9M |
| LMR Partners LLP | 0.04% | No change | 48,668 | $1.9M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -3.1% | 47,297 | $1.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -4.7% | 46,597 | $1.8M |
| Artia Global Partners LP | 0.63% | No change | 40,000 | $1.6M |
| Woodline Partners LP | 0.01% | New | 39,938 | $1.6M |
| Skandinaviska Enskilda Banken AB (publ) | 0.01% | No change | 40,376 | $1.6M |
| Prudential Financial Inc. | 0.00% | Add +177.7% | 39,000 | $1.5M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 39,000 | $1.5M |
| Rhenman & Partners Asset Management AB | 0.14% | No change | 35,000 | $1.4M |
| TLS Advisors LLC | 2.95% | No change | 32,956 | $1.3M |
| Thrivent Financial for Lutherans | 0.00% | Reduce -28.8% | 30,699 | $1.2M |
| Allostery Investments LP | 2.31% | — | 30,000 | $1.2M |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -84.0% | 26,094 | $1.0M |
| NJ State Employees Deferred Compensation Plan | 0.12% | No change | 25,000 | $980K |
| Rathbones Group PLC | 0.00% | No change | 23,666 | $928K |
| Natixis Advisors, LLC | 0.00% | Reduce -13.3% | 23,554 | $923K |
| Handelsbanken Fonder AB | 0.00% | No change | 22,700 | $890K |
| Assetmark, Inc. | 0.00% | Add +9.7% | 21,585 | $846K |
| Sanders Morris Harris LLC | 0.13% | No change | 21,500 | $843K |
| Knott David M Jr | 0.30% | No change | 20,866 | $818K |
| Stifel Financial Corp. | 0.00% | Reduce -4.1% | 20,688 | $811K |
| TD Asset Management Inc | 0.00% | No change | 20,430 | $801K |
| Nebula Research & Development LLC | 0.09% | Reduce -16.1% | 20,360 | $798K |
| Raymond James Financial Inc. | 0.00% | — | 20,331 | $797K |
| Cibc World Market Inc. | 0.00% | No change | 19,835 | $778K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +17.5% | 19,274 | $756K |
| Teacher Retirement System of Texas | 0.00% | Add +18.6% | 19,083 | $748K |
| Brevan Howard Capital Management LP | 0.02% | Add +58.2% | 19,005 | $745K |
| Arizona State Retirement System | 0.00% | Add +1.1% | 18,666 | $732K |
| Prelude Capital Management, LLC | 0.06% | No change | 18,266 | $716K |
| Barclays PLC | 0.00% | Add +20.9% | 18,127 | $711K |
| J. Safra Sarasin Holding AG | 0.01% | New | 17,786 | $697K |
| Boothbay Fund Management, LLC | 0.02% | Reduce -42.3% | 17,395 | $682K |
| China Universal Asset Management Co., Ltd. | 0.06% | Add +10.9% | 16,166 | $634K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 15,911 | $623K |
| Schonfeld Strategic Advisors LLC | 0.00% | Add +11.5% | 15,150 | $594K |
| Nicholas Investment Partners, LP | 0.06% | No change | 14,658 | $575K |
| Renaissance Technologies | 0.00% | Reduce -68.9% | 13,700 | $537K |
| Orion Porfolio Solutions, LLC | 0.01% | Reduce -7.4% | 13,436 | $527K |
| Orion Portfolio Solutions, LLC | 0.01% | Reduce -7.4% | 13,436 | $527K |
| SG Americas Securities, LLC | 0.00% | Add +72.3% | 13,293 | $521K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -4.0% | 13,048 | $511K |
| KLP Kapitalforvaltning As | 0.00% | — | 12,800 | $502K |
| Allianz Asset Management GmbH | 0.00% | Add +53.1% | 12,400 | $486K |
| Occudo Quantitative Strategies LP | 0.08% | Add +5.8% | 11,441 | $448K |
| Trexquant Investment LP | 0.01% | Reduce -32.6% | 11,397 | $447K |
| Jane Street Group, LLC | 0.00% | New | 11,138 | $437K |
| Elmwood Wealth Management, Inc. | 0.17% | Add +44.7% | 11,007 | $431K |
| Supplemental Annuity Collective Trust of NJ | 0.13% | No change | 11,000 | $431K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 10,633 | $417K |
| Birchview Capital, LP | 0.32% | No change | 10,000 | $392K |
| Tudor Investment Corporation | 0.00% | Reduce -76.4% | 8,671 | $340K |
| Fox Run Management, L.L.C. | 0.06% | Reduce -56.3% | 8,621 | $338K |
| Verition Fund Management LLC | 0.00% | New | 8,297 | $325K |
| Aquatic Capital Management LLC | 0.01% | New | 8,260 | $324K |
| Bellevue Group AG | 0.01% | No change | 8,200 | $321K |
| XTX Topco Ltd | 0.03% | New | 8,054 | $316K |
| HRT Financial LP | 0.00% | Reduce -75.8% | 7,171 | $281K |
| UBS Group AG | 0.00% | Reduce -49.5% | 6,705 | $263K |
| Squarepoint Ops LLC | 0.00% | Reduce -12.7% | 6,554 | $257K |
| Citigroup Inc. | 0.00% | Add +76.8% | 6,448 | $253K |
| Guggenheim Capital LLC | 0.00% | Reduce -41.9% | 6,177 | $242K |
| Tema ETFs LLC | 0.10% | — | 6,111 | $240K |
| NEOS Investment Management LLC | 0.01% | New | 6,111 | $240K |
| HighMark Wealth Management LLC | 0.14% | Add +22.0% | 6,100 | $239K |
| Vident Advisory, LLC | 0.00% | New | 5,413 | $212K |
| Magnetar Financial LLC | 0.01% | New | 5,363 | $210K |
| PNC Financial Services Group, Inc. | 0.00% | Add +3.6% | 5,140 | $201K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +0.4% | 5,019 | $197K |
| BNP Paribas Financial Markets | 0.00% | Reduce -4.0% | 3,332 | $131K |
| KBC Group NV | 0.00% | Add +39.8% | 2,742 | $107K |
| Avior Wealth Management, LLC | 0.00% | New | 2,569 | $101K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.3% | 2,541 | $99K |
| Quarry LP | 0.02% | New | 2,000 | $78K |
| Concourse Financial Group Securities, Inc. | 0.00% | No change | 2,000 | $78K |
| IFP Advisors, Inc | 0.00% | Reduce -1.0% | 1,958 | $77K |
| Virtus Advisers, LLC | 0.03% | Reduce -25.7% | 1,802 | $71K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,601 | $63K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -68.0% | 647 | $25K |
| US Bancorp \de | 0.00% | Reduce -3.3% | 586 | $23K |
| Signaturefd, LLC | 0.00% | Add +140.9% | 571 | $22K |
| State of Wyoming | 0.00% | No change | 544 | $21K |
| Parallel Advisors, LLC | 0.00% | Add +22.3% | 466 | $18K |
| Osaic Holdings, Inc. | 0.00% | Add +0.9% | 463 | $18K |
| First Horizon Advisors, Inc. | 0.00% | No change | 370 | $15K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 276 | $11K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -12.5% | 252 | $10K |
| Blue Trust, Inc. | 0.00% | Reduce -75.4% | 248 | $10K |
| National Bank of Canada | 0.00% | No change | 235 | $9K |
| Lindbrook Capital, LLC | 0.00% | Reduce -1.8% | 225 | $9K |
| Clearstead Advisors, LLC | 0.00% | No change | 218 | $9K |
| Spire Wealth Management | 0.00% | New | 200 | $8K |
| Bell Investment Advisors, Inc | 0.00% | Add +54.7% | 99 | $4K |
| Amundi | 0.00% | New | 89 | $4K |
| Quadrant Capital Group LLC | 0.00% | New | 66 | $3K |
| Principal Securities, Inc. | 0.00% | Add +28.9% | 58 | $2K |
| Cwm, LLC | 0.00% | Add +314.3% | 58 | $2K |
| GAMMA Investing LLC | 0.00% | Reduce -13.6% | 51 | $2K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | Add +2.8% | 37 | $1K |
| CVA Family Office, LLC | 0.00% | No change | 33 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -92.8% | 30 | $1K |
| Rhumbline Advisers | 0.00% | No change | 29 | $1K |
| Continuum Advisory, LLC | 0.00% | No change | 27 | $1K |
| Allworth Financial LP | 0.00% | No change | 12 | $471 |
| J.Safra Asset Management Corp | 0.00% | No change | 11 | $424 |
| C M Bidwell & Associates Ltd. | 0.00% | No change | 9 | $353 |
| Hexagon Capital Partners LLC | 0.00% | New | 6 | $235 |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.